Canis lupus familiaris (dog): 476215
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Entry
476215 CDS
T01007
Symbol
MAP3K5
Name
(RefSeq) mitogen-activated protein kinase kinase kinase 5
KO
K04426
mitogen-activated protein kinase kinase kinase 5 [EC:
2.7.11.25
]
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa01524
Platinum drug resistance
cfa04010
MAPK signaling pathway
cfa04071
Sphingolipid signaling pathway
cfa04141
Protein processing in endoplasmic reticulum
cfa04210
Apoptosis
cfa04530
Tight junction
cfa04668
TNF signaling pathway
cfa04714
Thermogenesis
cfa04722
Neurotrophin signaling pathway
cfa04932
Non-alcoholic fatty liver disease
cfa04936
Alcoholic liver disease
cfa05010
Alzheimer disease
cfa05012
Parkinson disease
cfa05014
Amyotrophic lateral sclerosis
cfa05016
Huntington disease
cfa05017
Spinocerebellar ataxia
cfa05022
Pathways of neurodegeneration - multiple diseases
cfa05208
Chemical carcinogenesis - reactive oxygen species
cfa05417
Lipid and atherosclerosis
cfa05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
476215 (MAP3K5)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
476215 (MAP3K5)
04668 TNF signaling pathway
476215 (MAP3K5)
04071 Sphingolipid signaling pathway
476215 (MAP3K5)
09140 Cellular Processes
09143 Cell growth and death
04210 Apoptosis
476215 (MAP3K5)
09144 Cellular community - eukaryotes
04530 Tight junction
476215 (MAP3K5)
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
476215 (MAP3K5)
09159 Environmental adaptation
04714 Thermogenesis
476215 (MAP3K5)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
476215 (MAP3K5)
09164 Neurodegenerative disease
05010 Alzheimer disease
476215 (MAP3K5)
05012 Parkinson disease
476215 (MAP3K5)
05014 Amyotrophic lateral sclerosis
476215 (MAP3K5)
05016 Huntington disease
476215 (MAP3K5)
05017 Spinocerebellar ataxia
476215 (MAP3K5)
05022 Pathways of neurodegeneration - multiple diseases
476215 (MAP3K5)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
476215 (MAP3K5)
05418 Fluid shear stress and atherosclerosis
476215 (MAP3K5)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
476215 (MAP3K5)
04932 Non-alcoholic fatty liver disease
476215 (MAP3K5)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
476215 (MAP3K5)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
cfa01001
]
476215 (MAP3K5)
Enzymes [BR:
cfa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.25 mitogen-activated protein kinase kinase kinase
476215 (MAP3K5)
Protein kinases [BR:
cfa01001
]
Serine/threonine kinases: STE group
STE11 family
476215 (MAP3K5)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
MAP3K_TRAF_bd
Pkinase
HisK-N-like
PK_Tyr_Ser-Thr
ASK_PH
TPR-S
DRHyd-ASK
Kinase-like
Pkinase_fungal
Motif
Other DBs
NCBI-GeneID:
476215
NCBI-ProteinID:
XP_533420
Ensembl:
ENSCAFG00000000251
VGNC:
42975
UniProt:
A0A8C0RVK6
A0A8I3RT53
LinkDB
All DBs
Position
1:complement(29990542..30188619)
Genome browser
AA seq
1366 aa
AA seq
DB search
MSAEAGEGITFSVPPFAEGGSCRRGGAAAPAEGPESQLPPPPPGSFWNVESAAAPGAGCP
AATSASSATRCRGSSGGGGGRRTTVAYVINEASQGQLVVAESEALQSLREACETVGATLE
TLHFGKLDFGETTVLDRFYNADIAVVEMSDAFRQPSLFYHLGVRESFSMANNIILYCDNN
SDSLQSLKEIICQKNTMCTGNYTFVPYMITPHNKVYCCDSSFMKGLTELMQPNFELLLGP
ICLPLVDRFIQLLKVAQASSSQYFRESILNDIRKARNLYTGKELAAELARIRQRVDNIEV
LTADIVINLLLSYRDIQDYDSIVKLVETLEKLPTFDLASHHHVKFHYAFALNRRNLPGDR
AKALDVMIPLVQSEGQVASDMYCLVGRIYKDMFLDSNFLDTESRDHGASWFKKAFESEPS
LQSGINYAVLLLAAGHQFESSFELRKVGVKLSSLLGKKGNLEKLQSYWEVGFFLGASVLA
NDHMRVIQASEKLFKLKTPAWYLKSIVETILIYKHFVKLTTDQPVAKQELVDFWMDFLVE
ATKTDVTVVRFPVLILEPTKIYQPSYLSINNEVEEKTISIWHVLPDDKKGIHEWNFSASS
VRGVSISKFEERCCFLYVLHNSDDFQIYFCTELHCKKFFEMVNTITEEKGRSTEEGDCET
DSLEYDYEYDENGDRVVLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLHEEIAL
HKHLKHKNIVQYLGSFSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQIL
EGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCTETFTGTLQYMAP
EIIDKGPRGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKVHPEIPESMS
AEAKAFILKCFEPDPDKRACANDLLIDEFLKVSSKKKKTQPKLSALSAGSNEYLRSISLP
VPVLVEDTSSSSEYGSVSPDTELRVDPFSFKMRAKSCGERDVKGIRTLFLGIPDENFEDH
SAPPSPEEKDSGFFMLRKDSERRATLHRILTEDQDKVVRNLMESLAQGPEEPKLKWEHIT
TLIASLREFVRSTDRKIIATTLSKLKLELDFDSHGISQVQVVLFGFQDAVNKVLRNHNIK
PHWMFALDSIIRKAVQTAITILVPELRPHFSLASESDTADQEDLDAEDDHEEQPSSQTVR
RPHAVIEDAVATSGVSTLSSTVSHDSQNAHRSLNVQLGRMKIETNRLLEELVQKEKELQA
LLHQAIEEKDQEIKHLKLKSQPIEIPGLPVCPRDSPGTNTEESELTEWLRDKGADEDTIS
RFLAEDYSLEDVLYYVTRDDLKCLRLRGGMLCTLWKAITDFRDTQA
NT seq
4101 nt
NT seq
+upstream
nt +downstream
nt
atgagcgccgaggcgggcgagggcatcactttctccgtgccacccttcgccgagggcggc
agctgccggaggggaggagcggcggcgccggccgagggcccggagagccaactaccaccg
ccgccgccgggcagcttctggaacgtggagagtgccgccgccccgggcgccggctgtccg
gctgccacctctgcgagcagcgccacccggtgccggggcagctctggtggcggaggcggc
cgacggaccacggtggcttatgtgatcaacgaagcgagccaggggcagctggtggtggcc
gagagcgaggccctgcagagcctgcgggaggcgtgcgagacggtgggcgccaccctggag
accctgcattttggcaaactggacttcggggaaaccacggtgctggaccgcttttacaac
gcagatattgctgtggtggagatgagtgatgccttccggcagccgtccttgttttaccac
ctgggagtgagagaaagtttcagcatggccaacaacatcatcctctactgtgataataat
tcagactctctgcagtcactgaaggaaatcatttgccagaagaatactatgtgcactggg
aactacacattcgtcccttacatgataactccacataacaaggtctactgctgtgatagc
agcttcatgaaagggttgacagagctcatgcaaccgaacttcgagctgcttctgggaccc
atatgcttacctcttgtggaccgtttcattcagcttctgaaggtggcacaagcaagttct
agccagtacttccgggaatctatactcaatgatatcaggaaagctcgtaatttatacact
ggtaaagaattggcagctgaattggcaagaattcggcagcgagtagacaatattgaagtc
ttgacagcagatattgtcataaacctgttactttcctacagagatatccaggactatgat
tctattgtgaagctggtagagacgttagaaaaactgccaacttttgatttggcttcccat
caccatgtgaagtttcattatgcatttgcactgaataggagaaacctccctggagataga
gcaaaagctcttgatgttatgatccccttggtgcaaagtgaagggcaggttgcttcagat
atgtattgcctagttggtcgaatctacaaagatatgtttttggactctaatttcctggac
actgagagtagagaccatggagcttcttggttcaaaaaggcatttgaatctgagccatca
ctacagtcaggaattaattatgcagtccttctcctggcagctgggcaccagtttgaatct
tcctttgagctccggaaagttggagtgaagctgagtagcctccttggtaaaaagggaaac
ttagaaaaactccagagctactgggaagttggattttttctgggtgccagtgtcttggcc
aatgatcacatgagagtcatccaagcatctgaaaagctttttaagctgaagacacccgca
tggtacctcaaatctattgtagagacaattttgatatataagcattttgtgaaactgact
acagaccagcctgtggccaaacaggagctcgtggacttctggatggatttcctggttgaa
gccacaaagacagatgttaccgtagttaggtttccagtattaatattagaaccaaccaaa
atctatcagccttcatatttgtctatcaacaatgaagttgaggaaaagaccatatctatt
tggcacgtgcttcctgatgacaagaaaggtatacatgagtggaattttagtgcttcttct
gtcaggggagtgagtatttctaaatttgaagaacgatgctgttttctttatgtgcttcat
aattctgatgatttccaaatctacttctgtacagaacttcattgtaaaaagttttttgaa
atggtgaacaccatcactgaagagaaggggagaagcacagaggaaggtgattgtgaaact
gactccctggagtatgactatgaatatgatgagaatggtgacagagtcgttctagggaaa
ggcacttatgggatcgtctacgcaggccgagacctgagcaaccaagtcagaatcgctata
aaggaaatcccagagagagatagcagatactctcagcctctacatgaagaaatagcattg
cataagcatctgaagcacaaaaatattgtccagtatctgggctctttcagtgagaatggt
ttcatcaaaatcttcatggagcaggtcccaggaggaagtctttctgctctccttcgttcc
aaatggggcccattgaaggacaatgagcaaacaattggcttttatacaaagcaaatactt
gaaggattaaaatacctccatgacaatcaaatagtccaccgagatataaagggcgacaac
gtgttgattaatacctatagtggtgttctcaagatctcggacttcgggacatcaaagagg
ctcgctggcataaacccatgtactgaaacttttactggtactcttcagtacatggcacca
gagatcatagacaaaggaccacgaggctacgggaaagcagcagacatctggtctttgggc
tgcacaatcatcgaaatggccacagggaaaccacctttctatgaactgggagaaccacaa
gcagctatgttcaaggtgggaatgtttaaagtccacccggagattccagagtccatgtca
gcagaggccaaggcattcatactgaagtgttttgaaccagaccctgacaagagagcctgt
gctaacgacttgcttattgatgaattcttaaaagtttcaagcaaaaagaaaaagacacaa
cctaagctttcagccctctcagctggatcaaatgagtatcttagaagcatatccttgccg
gtgcctgtcctggtggaagacacgagcagcagcagcgagtacggctcggtttcccccgac
acggagttaagggtggaccccttctctttcaaaatgagagccaaatcctgtggagagaga
gatgtaaaaggaatacggacactctttttgggcattccggatgaaaattttgaagaccac
agtgctcccccttcccctgaagaaaaagattctggattctttatgctgagaaaggacagt
gagagacgggccacccttcataggatcctgactgaagaccaagacaaagtcgtgagaaac
ttaatggaatctttggcccaggggcctgaagaacctaagctaaaatgggaacatatcaca
accctcatcgcaagcctcagagagtttgtgagatccactgaccgaaaaatcatagccacc
acactgtccaagctgaagctggaacttgactttgacagccatggcattagtcaagtacag
gtggtgctcttcggctttcaggatgctgtcaataaagttcttcggaatcataatatcaag
ccacactggatgtttgccttagacagtatcatccgaaaggcagtgcagacggccattacc
attctggttccagaactgaggccacacttcagccttgcatctgagagtgataccgctgat
caagaagacttggatgcagaagatgaccatgaagagcagccttccagccaaactgtccga
agacctcatgctgtcattgaagatgctgtggctacctcaggggtgagcacgctcagttct
actgtatcccacgactcccagaatgctcaccgctcactcaatgtgcagctcggaaggatg
aaaatagaaactaatagactactggaagaattggttcagaaagagaaagaattacaggca
ctccttcatcaagcaattgaagaaaaagaccaagaaattaaacatctgaaacttaagtcc
caaccaatagagattccgggattgccagtatgcccccgggattctcctggcacaaatact
gaagaatctgaacttactgagtggctgagagacaagggagctgatgaagacactataagt
cggtttttggctgaggattattcactagaggatgttctctactatgttacacgtgatgat
ttaaaatgcctgagactaaggggagggatgctctgcacactgtggaaggccatcaccgac
tttcgagacacacaggcttga
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integrated database retrieval system
