Canis lupus familiaris (dog): 479190 Help Entry 479190            CDS       T01007                                  Symbol MTR Name (RefSeq) methionine synthase isoform X2   KO K00548   5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13] Organism cfa  Canis lupus familiaris (dog) Pathway cfa00270   Cysteine and methionine metabolism cfa00450   Selenocompound metabolism cfa00670   One carbon pool by folate cfa01100   Metabolic pathways cfa01230   Biosynthesis of amino acids cfa01523   Antifolate resistance cfa04980   Cobalamin transport and metabolism cfa04981   Folate transport and metabolism Brite KEGG Orthology (KO) [BR:cfa00001]  09100 Metabolism   09105 Amino acid metabolism    00270 Cysteine and methionine metabolism     479190 (MTR)   09106 Metabolism of other amino acids    00450 Selenocompound metabolism     479190 (MTR)   09108 Metabolism of cofactors and vitamins    00670 One carbon pool by folate     479190 (MTR)  09150 Organismal Systems   09154 Digestive system    04981 Folate transport and metabolism     479190 (MTR)    04980 Cobalamin transport and metabolism     479190 (MTR)  09160 Human Diseases   09176 Drug resistance: antineoplastic    01523 Antifolate resistance     479190 (MTR) Enzymes [BR:cfa01000]  2. Transferases   2.1  Transferring one-carbon groups    2.1.1  Methyltransferases     2.1.1.13  methionine synthase      479190 (MTR) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Met_synt_B12 S-methyl_trans Pterin_bind B12-binding_2 B12-binding CdhD Motif Other DBs NCBI-GeneID:  479190 NCBI-ProteinID:  XP_005618839 Ensembl:  ENSCAFG00000010464 VGNC:  43491 UniProt:  A0A8I3MG95 A0A8P0NCJ6 LinkDB All DBs Position 4:complement(3267770..3375365) Genome browser AA seq 1265 aa AA seqDB search MSPALPALTPSASVKKSLQDEIEAILRERIMVLDGGMGTMIQRHKLSEEDFRGHEFQDHA RSLKGNNDILSITQPNVIYQIHKDYLLAGADIIETNTFSSTNVAQADYGLEHLAYQMNKC SAGVARKAAEEVSFQTGIKRFVAGALGPTNKTLSVSPSVEKPDYRNITFDELVEAYKEQA KGLLDGGVDILLIETIFDTANAKAALFALQTLFEEEYSPRPIFISGTIIDKSGRTLSGQT GEAFVISVSHASPLCIGLNCALGAAEMRPFIETIGKCTTAYVLCYPNAGLPNTFGDYDET PQMMAMQLKDFAMDGLVNIVGGCCGTSPDHIREIAKAVKNCKPRVPPATVFEEHMLLSGL EPFRIGPYTNFVNIGERCNVAGSRKFAKLVMAGNYEEALSVAKAQVEMGAQVLDINMDDG MLDGPSAMTKFCNFIASEPDIAKVPLCIDSSNFAVIEAGLKCCQGKCIVNSISLKEGEDD FLEKARKIKKFGAAVVVMAFDEEGQATETDTKIRVCIRAYHLLVNKLGFNPNDIIFDPNI LTIGTGMEEHNLYAVNFIHATKIIKETLPGVRVSGGLSNLSFSFRGMEAIREAMHGVFLY HAIKFGMDMGIVNAGSLPVYDDIHKELLQLCEDLIWNKDPEATEKLLRYAQTHGKGGKKV IQTDEWRNGPIEERLEYALVKGIEKHIIEDTEEARLNQEKYPRPLNIIEGPLMNGMKVVG DLFGAGKMFLPQVIKSARVMKKAVGHLIPFMEEEREKNKTHAGTMEEEDPYQGTIVLATV KGDVHDIGKNIVGVVLGCNNFRVIDLGVMTPCDKILKAALDHKADIIGLSGLITPSLDEM IFVAKEMERLAIKIPLLIGGATTSRTHTAVKIAPRYSAPVIHVLDASKSVVVCSQLLDEN LKDEYFEEIMEEYEDIRQDHYESLKERRYLTLSQARKNGFHIDWLSEPPPVKPTFLGTRV FEDYDLQKLVAYIDWKPFFDVWQLRGKYPNRSFPKIFKDKAVGEEAKKVYDDAQNMLKVL ISQKKLQARGVVGFWPAQSVQDDIHLYAEDAAPQAAEPIATFHGLRQQAEKDSASTDPYH CLSDFIAPLHSGVRDYLGLFAVACFGVEELSKAYEQECDDYSSIMVKALGDRLAEAFAEE LHERVRRELWAYCSCEQLDVVDLRRLRYEGIRPAPGYPSQPDHSEKLTMWKLANVEQCTG IRLTESLAMAPASAVSGLYFSNLKSKYFAVGKISKDQIEDYALRKNMSVAEVEKWLGPIL GYDTE NT seq 3798 nt NT seq  +upstreamnt  +downstreamnt atgtccccggcgctgcccgcgctgacgccttccgcaagtgtgaagaaaagcctgcaggat gagattgaagccattctgcgggagaggattatggtactggatggagggatggggaccatg atccagaggcacaagctgagtgaagaagacttccgaggtcacgaatttcaagatcatgcc aggtcactgaaaggcaacaatgacattttaagtataactcaacccaatgtcatttaccaa atccataaggattacttgctggccggggcagatatcattgaaacaaatacttttagtagc actaatgttgcccaagctgactatggcctcgaacacttggcctaccagatgaacaagtgc tctgcaggagtggccagaaaagcagccgaggaggtatctttccagacgggaattaagaga tttgtggcaggagcactgggtccaactaataagacactgtctgtgtccccgtcggtggaa aaaccagattataggaatattacattcgatgagcttgttgaagcatacaaagagcaggcc aaagggctcctggatggtggagttgatatcttactcattgaaactatttttgatactgcc aatgccaaggcagccttgtttgcactccaaacactttttgaagaggagtattcccccagg cctatcttcatttcggggacaattattgataaaagtgggcgaactctttctggacagaca ggagaggcatttgtcatcagtgtgtctcatgcaagcccactctgtatcggattaaactgt gctctgggtgcggctgaaatgagaccttttattgaaacaattggaaaatgtacaacagcc tatgtcctctgttatcccaatgcaggtcttcccaacacatttggtgactacgatgaaact ccgcaaatgatggccatgcagctaaaggactttgctatggatggcttggtcaatatagtt ggtggttgctgtggtacgtcaccagatcatatcagggagattgctaaagctgtgaaaaac tgtaagcctagagttccaccagccactgtttttgaggagcatatgttactatctggtcta gaacccttcaggattggaccgtacaccaactttgttaacattggagagcgctgtaacgtg gcaggatccaggaagtttgctaaactcgtcatggcaggaaactatgaagaagcactgagt gttgccaaagcacaggtggaaatgggagcgcaggtgttggatatcaacatggatgatggc atgcttgatggtccgagtgccatgaccaaattttgcaactttatcgcttcggagcctgac attgccaaggtgcccctgtgcattgactcttccaattttgctgtgattgaagctggcttg aagtgctgccagggaaaatgcattgtcaacagcattagtctgaaggagggagaggatgac ttcttggagaaggctaggaagattaagaagtttggagctgctgtggtggtcatggctttt gatgaagaagggcaggcgacagaaacagacacaaaaatcagagtgtgcatccgggcctac catctacttgtgaataaactgggctttaatccaaatgacatcatctttgaccccaatatc ctcaccattggcactgggatggaagagcacaacttgtatgctgttaattttattcacgca acaaaaatcattaaagaaacattacctggagtcagagtaagtggcggtctttccaacttg tccttctcctttcgcggcatggaagccattcgagaagcaatgcatggtgttttcctttac catgcaatcaagtttggtatggacatggggatagtgaatgccggaagcctccccgtctat gacgacatccataaggaactcctccagctctgtgaagacctcatctggaataaagaccct gaggctacggagaagctcctacgctatgctcagactcacggcaaaggagggaagaaagtc atccagactgatgagtggaggaatggccccattgaagagcgccttgagtacgccctcgtg aagggtattgaaaaacatattattgaggacactgaggaagccaggttaaaccaggaaaaa tatccccggcctctgaatatcattgaagggcctctgatgaatggcatgaaagttgttggt gacctttttggagctggaaaaatgtttctgcctcaggttataaaatcagctcgagtcatg aagaaggctgttggccaccttattcctttcatggaagaagaaagagaaaaaaataagacg catgctggcacaatggaagaagaggacccataccagggcaccattgtgctggccactgtg aaaggtgatgtgcacgatataggcaagaacatagttggtgtcgtccttggctgcaataat tttagagttattgacttaggagtcatgactccctgtgataagattctgaaagctgctctt gaccacaaagcagatataattggcctatcaggacttatcactccttccctggatgaaatg atttttgttgccaaggaaatggagagactggctataaagattccactgctgattggagga gccaccacatcaagaacccatacagcagtgaaaatagctccaagatacagcgcgcctgta atccatgtcctggatgcatccaagagtgtggtggtgtgctcgcaactattagatgagaat ctaaaggatgaatattttgaggagatcatggaagagtatgaagatattagacaggaccat tacgaatctctcaaggagagaagatatttaaccttaagtcaagctagaaaaaatggtttc catattgactggctgtcagagccgcctccagtgaagcccacgttccttgggactcgagtc tttgaagactacgacctgcaaaagctggtggcctacatcgactggaaacccttctttgat gtctggcagctccggggcaaatacccgaatcgaagctttcccaagatatttaaggacaaa gctgtaggcgaagaggccaaaaaagtctatgatgatgcccaaaacatgctgaaagtgctc atcagtcagaagaagctgcaagccaggggtgtggtagggttttggccagcgcagagtgtg caagacgacattcacctgtacgcagaggatgcagcgccgcaggccgcagagcccatagcc accttccatgggctaaggcagcaggccgagaaggactctgccagcacagacccctaccac tgcctctccgacttcattgctcccctgcattcgggcgtccgcgactacctgggcctcttt gccgttgcctgctttggggtggaagagctgagcaaggcctatgagcaggagtgtgatgac tacagcagcatcatggtcaaggctctgggagaccggctggctgaggcctttgcggaggag ctccacgagcgggtccgcagggagctgtgggcgtactgcagctgtgagcagctggatgtt gtggacctgcggaggctgcgctacgaaggcatccgcccggcccccggctaccccagccag cctgaccacagcgagaagctcaccatgtggaagctcgccaacgtggaacagtgcacaggc attaggttaacagaatccttagcaatggcacctgcttcagcagtatccggcctttacttc tccaatttgaagtccaaatactttgcagtggggaagatttccaaggaccagattgaagat tatgctctgaggaagaacatgtctgtggctgaggttgagaaatggctgggacccattctg ggatatgatacagagtaa

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