Canis lupus familiaris (dog): 479476
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Entry
479476 CDS
T01007
Symbol
ALOX12
Name
(RefSeq) polyunsaturated fatty acid lipoxygenase ALOX12
KO
K00458
arachidonate 12-lipoxygenase [EC:
1.13.11.31
]
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa00590
Arachidonic acid metabolism
cfa01100
Metabolic pathways
cfa04726
Serotonergic synapse
cfa04750
Inflammatory mediator regulation of TRP channels
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09100 Metabolism
09103 Lipid metabolism
00590 Arachidonic acid metabolism
479476 (ALOX12)
09150 Organismal Systems
09156 Nervous system
04726 Serotonergic synapse
479476 (ALOX12)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
479476 (ALOX12)
Enzymes [BR:
cfa01000
]
1. Oxidoreductases
1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
1.13.11 With incorporation of two atoms of oxygen
1.13.11.31 arachidonate 12-lipoxygenase
479476 (ALOX12)
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Motif
Pfam:
Lipoxygenase
PLAT
Motif
Other DBs
NCBI-GeneID:
479476
NCBI-ProteinID:
XP_536613
Ensembl:
ENSCAFG00000015949
VGNC:
49900
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Position
5:32164885..32176845
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AA seq
663 aa
AA seq
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MGRYCVRVTTGAWLFSGSHNRVQLWLVGARGDAELELQLRPARGQEEEFDLDIPKDLGPL
QFVKLCKHHSLVDDAWFCDLITVRGPGASEEAAFPCYQWVQGQGVLSLPEGTARLAGDNA
LDVFQKHREKELKERQKLYCWDTWKEGLPLTIAAGCQDDLPPNMRFHEDKRLDFEWALKA
GALEMVLKRIYTLLSSWNHLEDFDQIFWGQKSILAEKVHQCWQDDELFGYQFLNGANPML
LRRSACLPSRLVLPPGMEALRAQLERELQNGSLFEADFILLDGLPTNVIRGEKQYLAAPL
VLLKMEPNGKLLPMLIQIQPPGPSSPTSPLFLPSDPPLAWLLAKVWVRNSDFQLHQLQYH
LLNTHLVAEVMAVATMRCLPGLHPVFKLLIPHIRYTMEINTRARTQLISEGGIFDKVVST
GGGGHVQLLRRAMAQLTYRSLCPPDDLADRGLLGIPSALYAHDALRLWGIIAQYVEGIVH
LFYHRDDVVRGDSELQAWCREITEVGLCHAQERGFPISFQSRKQLCHFLTMCIFTCTAQH
GAINQGQLDWYAWVPNAPCTMRMPPPTTKEEVKMATVMGSLPDVRQACLQMTITWHLGRR
QPDMVPLGHHKEKYFSSPKAKAVLNQFQTDLENLEREITARNEQLDLPYDYLKPSRIENS
VTI
NT seq
1992 nt
NT seq
+upstream
nt +downstream
nt
atgggccgctactgcgtccgcgtgaccaccggggcttggctcttctcaggctcgcataac
cgcgtgcagctctggctggtcggggcgcgcggggacgcggagctggagctgcagctgcgg
ccggcgcggggtcaggaggaggagtttgatctcgacattcccaaggacctggggcccctg
cagttcgtgaagttgtgcaaacaccactccctggtggacgacgcctggttctgcgacctc
atcacggtgcggggcccgggagcctccgaggaggccgccttcccctgctaccaatgggtg
cagggccagggcgtgctgagcctgccggagggcaccgcacgcctggcaggagataatgca
ctggatgtgttccagaagcatcgagagaaagaactgaaggaaagacaaaagctgtactgc
tgggacacctggaaggaggggctgcccctgacaattgcagccgggtgtcaggatgatctg
cctccaaatatgagattccatgaggacaagaggctggacttcgagtgggcactgaaggcg
ggggcgctggagatggtcctcaaacgcatctacactctcctgagctcctggaaccacctg
gaggattttgatcagatcttctggggccagaagagcattctggctgagaaggttcaccag
tgctggcaggatgatgagctttttggctaccagttcctcaatggcgccaaccccatgctg
ttgagacgctctgcctgcctgccctcccgtctagtgctgcccccagggatggaggcactt
cgggcccagctggagagagagctccagaatggttctctgttcgaggctgacttcatcctc
ctggatggacttccaaccaatgtgatccggggagagaagcagtacctggctgcccccctc
gtcctgctgaagatggaacccaatgggaagctgctgcccatgcttatccagatccagcct
cccggccccagctcccccacctcgccgctgttcctgccctcagaccccccacttgcctgg
ctcctggcaaaggtctgggtccgaaattcagatttccaactgcaccagctccagtatcac
ctgctaaacactcatctggtggccgaggtcatggctgtggccaccatgaggtgcctcccg
gggctgcaccctgtcttcaagctcctgatcccgcatatccgctacaccatggagatcaac
acgcgggccagaacccagctcatctcagaagggggaatattcgataaggtggtgagcacg
ggtggagggggccatgtgcagctgctccgtcgggccatggctcagctgacctaccgttcc
ctctgtcctcctgatgacctggctgaccggggcctgctggggatcccaagtgccctctat
gcccacgatgctctacggctctgggggatcattgcccagtacgtggagggcattgtccac
ctcttctaccaccgggatgacgtcgtgagaggggactctgagctgcaggcctggtgtcgg
gagatcactgaggtggggctgtgccacgcccaggagcgaggtttccccatctccttccag
tcccggaagcaactgtgccacttccttaccatgtgcatcttcacatgcactgctcagcac
ggggccatcaaccagggccagctggactggtatgcctgggtccctaatgccccatgcaca
atgcggatgcccccacctaccaccaaggaagaggtgaaaatggctacagtgatgggctca
ctacctgatgtccgacaggcttgtcttcaaatgaccatcacgtggcatctgggtcgccgc
cagccagacatggtgcctctgggacatcacaaagaaaagtatttctcaagccccaaggcc
aaggctgtattaaaccaattccaaacagatttggaaaacctagaaagagagattacagcc
cggaatgagcagctcgacctgccctatgattacctgaaacccagccgcatagagaatagt
gtcactatctga
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