KEGG   Canis lupus familiaris (dog): 479875
Entry
479875            CDS       T01007                                 
Symbol
PDPK1
Name
(RefSeq) 3-phosphoinositide-dependent protein kinase 1 isoform X3
  KO
K06276  3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa01524  Platinum drug resistance
cfa03320  PPAR signaling pathway
cfa04068  FoxO signaling pathway
cfa04071  Sphingolipid signaling pathway
cfa04140  Autophagy - animal
cfa04150  mTOR signaling pathway
cfa04151  PI3K-Akt signaling pathway
cfa04152  AMPK signaling pathway
cfa04210  Apoptosis
cfa04360  Axon guidance
cfa04510  Focal adhesion
cfa04660  T cell receptor signaling pathway
cfa04664  Fc epsilon RI signaling pathway
cfa04722  Neurotrophin signaling pathway
cfa04910  Insulin signaling pathway
cfa04919  Thyroid hormone signaling pathway
cfa04931  Insulin resistance
cfa04960  Aldosterone-regulated sodium reabsorption
cfa05145  Toxoplasmosis
cfa05205  Proteoglycans in cancer
cfa05208  Chemical carcinogenesis - reactive oxygen species
cfa05213  Endometrial cancer
cfa05215  Prostate cancer
cfa05223  Non-small cell lung cancer
cfa05231  Choline metabolism in cancer
cfa05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    479875 (PDPK1)
   04071 Sphingolipid signaling pathway
    479875 (PDPK1)
   04151 PI3K-Akt signaling pathway
    479875 (PDPK1)
   04152 AMPK signaling pathway
    479875 (PDPK1)
   04150 mTOR signaling pathway
    479875 (PDPK1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    479875 (PDPK1)
  09143 Cell growth and death
   04210 Apoptosis
    479875 (PDPK1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    479875 (PDPK1)
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    479875 (PDPK1)
   04664 Fc epsilon RI signaling pathway
    479875 (PDPK1)
  09152 Endocrine system
   04910 Insulin signaling pathway
    479875 (PDPK1)
   03320 PPAR signaling pathway
    479875 (PDPK1)
   04919 Thyroid hormone signaling pathway
    479875 (PDPK1)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    479875 (PDPK1)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    479875 (PDPK1)
  09158 Development and regeneration
   04360 Axon guidance
    479875 (PDPK1)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    479875 (PDPK1)
   05208 Chemical carcinogenesis - reactive oxygen species
    479875 (PDPK1)
   05231 Choline metabolism in cancer
    479875 (PDPK1)
  09162 Cancer: specific types
   05215 Prostate cancer
    479875 (PDPK1)
   05213 Endometrial cancer
    479875 (PDPK1)
   05223 Non-small cell lung cancer
    479875 (PDPK1)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    479875 (PDPK1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    479875 (PDPK1)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    479875 (PDPK1)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    479875 (PDPK1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:cfa01001]
    479875 (PDPK1)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:cfa04131]
    479875 (PDPK1)
Enzymes [BR:cfa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     479875 (PDPK1)
Protein kinases [BR:cfa01001]
 Serine/threonine kinases: AGC group
  PDK1 family
   479875 (PDPK1)
Membrane trafficking [BR:cfa04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Acrosomal exocytosis proteins
    479875 (PDPK1)
SSDB
Motif
Pfam: Pkinase PH_3 PK_Tyr_Ser-Thr Kinase-like Pkinase_fungal ABC1 Haspin_kinase APH Kdo
Other DBs
NCBI-GeneID: 479875
NCBI-ProteinID: XP_005621734
Ensembl: ENSCAFG00000019358
VGNC: 54055
LinkDB
Position
6:complement(39665293..39744671)
AA seq 555 aa
MGRIEYDTVPIQSSVVLCSCPSPSMVRTQTESGTAPGIPSGGSRQAPTMDSTAAESRPST
NSLQHTTQPPPQPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKE
NKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETC
TRFYTAEMVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANS
FVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDF
PEKFFPKARDLVEKLLVLDATKRLGCEEMGGYSPLRAHPFFESITWENLQHQTPPKLTAY
LPAMSEDDEDCYGNYDNLLSQFGCMQVSSSSSSHSLSASDAGLPQMAGSNIEQYIHDLDT
NSFELDLEFSEDEKRLLLEKQASGNPWHQFVENNLILKMGPVDKRKGLFARRRQLLLTEG
PHLYYVDPVNKVLKGEIPWSQELRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKWCKKIQE
VWRHRYQSHPDAAVQ
NT seq 1668 nt   +upstreamnt  +downstreamnt
atggggagaatagaatatgacaccgttcctatccagtccagtgtggtgttatgttcttgc
ccgtccccatcaatggtgaggacccagactgagtccggcacggcccccggcattcccagt
ggtggtagcagacaggcccccaccatggacagcaccgcggctgagtctcgaccgagcacc
aactcgctgcaacacaccacacagccgccaccacagcctcggaagaaacggcctgaagac
ttcaaatttgggaaaattcttggtgaaggctctttttccacagttgttctagcccgagaa
ctggcaacctcaagggaatatgctattaaaattctagagaaacgtcacattatcaaagag
aacaaggtcccgtatgtaaccagagagagagacgtgatgtcacgcctggatcacccgttc
tttgttaaactttacttcacatttcaggatgatgaaaagctgtactttggtcttagttat
gccaaaaatggagaactacttaaatatattcgcaaaattggctcattcgatgagacatgc
acccggttttacacggccgagatggtgtcagctctggagtacttgcatggcaagggcatc
attcacagggacctgaaaccagaaaacattttgttaaatgaagacatgcacatccagatc
acagattttggaactgcaaaagtactatccccggagagtaaacaagccagggccaactcg
tttgtcggaacagcccagtatgtgtctccagaactgctcacagagaaatcggcgtgtaag
agttcagacctttgggctctcggatgtataatataccagctcgtggcaggactgccgcct
tttcgagcaggaaatgaatatcttatatttcagaagatcattaagttggagtatgacttt
cctgaaaaattcttccctaaggcaagagaccttgtggaaaaacttttggttttagatgcc
acgaagcgattaggctgtgaggaaatgggagggtacagccccctgcgagctcatccattc
ttcgagtccatcacatgggagaacctgcagcatcagacgcctccaaagctcactgcctac
ctgccagcgatgtcggaggatgatgaggactgctacggaaactatgacaacctcctgagc
cagtttggctgtatgcaggtgtcttcgtcttcctcctcccactccctgtccgcctcggac
gcaggcctgccgcagatggcgggcagcaacatcgagcagtatatccatgatctggacact
aattcttttgaactggacttagagttctccgaagatgagaagaggttgttactggagaag
caggccagtggaaacccttggcaccagtttgtagaaaataacttaatactaaagatgggt
cccgtagataagcgaaagggcttgtttgcacgacgacgacagttactgctcacagaaggg
ccacacttgtattatgtggatcctgtcaacaaagtcctgaaaggtgaaattccatggtca
caagaactccgaccagaggccaagaactttaaaaccttctttgtgcacacgccaaacagg
acgtattacctgatggacccgagtgggaatgctcacaaatggtgcaaaaagatccaggaa
gtgtggagacacagataccagagccacccagatgccgccgtgcagtga

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