Canis lupus familiaris (dog): 483009 Help Entry 483009            CDS       T01007                                  Symbol CAD Name (RefSeq) CAD protein isoform X1   KO K11540   carbamoyl-phosphate synthase / aspartate carbamoyltransferase / dihydroorotase [EC:6.3.5.5 2.1.3.2 3.5.2.3] Organism cfa  Canis lupus familiaris (dog) Pathway cfa00220   Arginine biosynthesis cfa00240   Pyrimidine metabolism cfa00250   Alanine, aspartate and glutamate metabolism cfa01100   Metabolic pathways cfa01240   Biosynthesis of cofactors Module cfa_M00051   De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP Brite KEGG Orthology (KO) [BR:cfa00001]  09100 Metabolism   09104 Nucleotide metabolism    00240 Pyrimidine metabolism     483009 (CAD)   09105 Amino acid metabolism    00250 Alanine, aspartate and glutamate metabolism     483009 (CAD)    00220 Arginine biosynthesis     483009 (CAD)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:cfa01002]     483009 (CAD) Enzymes [BR:cfa01000]  2. Transferases   2.1  Transferring one-carbon groups    2.1.3  Carboxy- and carbamoyltransferases     2.1.3.2  aspartate carbamoyltransferase      483009 (CAD)  3. Hydrolases   3.5  Acting on carbon-nitrogen bonds, other than peptide bonds    3.5.2  In cyclic amides     3.5.2.3  dihydroorotase      483009 (CAD)  6. Ligases   6.3  Forming carbon-nitrogen bonds    6.3.5  Carbon-nitrogen ligases with glutamine as amido-N-donor     6.3.5.5  carbamoyl-phosphate synthase (glutamine-hydrolysing)      483009 (CAD) Peptidases and inhibitors [BR:cfa01002]  Cysteine peptidases   Family C26: gamma-glutamyl hydrolase family    483009 (CAD)  Metallo peptidases   Family M38: beta-aspartyl dipeptidase family    483009 (CAD) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  CPSase_L_D2 GATase CPSase_sm_chain OTCace_N OTCace CPSase_L_D3 ATP-grasp Dala_Dala_lig_C MGS ATPgrasp_Ter Amidohydro_1 ATP-grasp_3 Peptidase_C26 GARS_A Motif Other DBs NCBI-GeneID:  483009 NCBI-ProteinID:  XP_005630306 Ensembl:  ENSCAFG00000004767 VGNC:  106593 UniProt:  A0A8C0MM07 LinkDB All DBs Position 17:21090639..21113701 Genome browser AA seq 2242 aa AA seqDB search MAALMLEDGSVLRGQPFGAAVSTAGEVVFQTGMVGYPEALTDPSYKAQILVLTYPLIGNY GIPTDEVDEFGLSKWFESSGIHVAGLVVGECCPTPSHWSATRTLHQWLQQHGIPGLQGVD TRELTKKLREQGSLLGKLVQDGTEPSALPFLDPNARPLVPEVSIKAPRVFNAGGTPRILA LDCGLKYNQIRCLCQRGAEVTVVPWDHTLDSQEYEGVFLSNGPGDPASYPSVVSTLSRVI SEPNPRPVFGICLGHQLLALAIGAKTYKMRYGNRGHNQPCLLVGSGRCFLTSQNHGFAVE TDSLPAGWLPLFTNANDRSNEGIVHDSLPFFSVQFHPEHQAGPSDMELLFDIFLETVKEA TAGNPGGWTVRERLIERLCPPGIPTPGSGLPPPRKVLILGSGGLSIGQAGEFDYSGSQAI KALKEENIQTLLINPNIATVQTSQGLADKVYFLPITPHYVTQVIRNERPDGILLTFGGQT ALNCGVELTKAGVLARYGVRVLGTPVETIELTEDRRAFASRMAEIGEHVAPSEAASSLEQ AQAAAERLGYPVLVRAAFALGGLGSGFASNRDELSALVAPAFAHTSQVLVDKSLKGWKEI EYEVVRDAYGNCVTVCNMENLDPLGIHTGESIVVAPSQTLNDREYQLLRQTAIKVTQHLG IVGECNVQYALNPESEQYYIIEVNARLSRSSALASKATGYPLAYVAAKLALGIPLPELRN SVTGGTAAFEPSLDYCVVKIPRWDLSKFLRVSTKIGSCMKSVGEVMGIGRSFEEAFQKAL RMVDENCVGFDHTVKPVSDMELETPTDKRIFVVAAALWAGYSVERLYQLTRIDRWFLHRM KRIIAHAQLLEQHRGQPLPPDLLHQAKRLGFSDKQIALAVLSTELAVRKLRQELGICPAV KQIDTVAAEWPAQTNYLYLTYWGTTHDLTFRTPHVLVLGSGVYRIGSSVEFDWCAVGCIR QLRKMGYKTIMVNYNPETVSTDYDMCDRLYFDEISFEVVMDIYELENPEGVILSMGGQLP NNMAMALHRQQCRVLGTSPEAIDSAENRFKFSRLLDTIGISQPQWRELSDLESARQFCQT VGYPCVVRPSYVLSGAAMNVAYTDGDLERFLSSAAAVSKEHPVVISKFIQEAKEIDVDAV ARDGVVAAIAISEHVENAGVHSGDATLVTPPQDITAKTLERIKAIVHAVGQELQVTGPFN LQLIAKDDQLKVIECNVRVSRSFPFVSKTLGVDLVALATRVIMGEEVEPVGLMTGSGVVG VKVPQFSFSRLAGADVVLGVEMTSTGEVAGFGESRCEAYLKAMLSTGFKIPKKNILLTIG SYKNKSELLPTVRLLESLGYSLYASLGTADFYTEHGVKVTAVDWHFEEAVDGECPPQRSI LEQLAENHFELVINLSMRGAGGRRLSSFVTKGYRTRRLAADFSVPLIIDIKCTKLFVEAL GQIGPAPPLKVHVDCMTSQKLVRLPGLIDIHVHLREPGGTHKEDFASGTAAALAGGITMV CAMPNTRPPIIDAPALALAQKLAEAGARCDFTLFLGASSENAGTLGAVAGSAAGLKLYLN ETFSELRLDNVAQWMEHFETWPSHLPIVAHAERQNVAAILMVAQLTQRSVHICHVARKEE ILLIKAAKARGLPVTCEVAPHHLFLSCDDLERLGPGKGEVRPELGSRQDVEALWENMAVI DCFASDHAPHTLEEKCGPRPPPGFPGLETMLPLLLTAVSEGRLSLDDLLQRLHHNPRRIF HLPPQEDTYVEVDLEHEWTIPSHMPFSKAHWTPFEGQKVKGTVRRVVLRGEVAYIDGQVL VPPGYGQDVRKWPQGTVPQLAPPAPAASEITTTPERPRRAVPGLPDGRFHLPPRIHRASD PGLPAVFLRPGAGIPRGSRTWAEEPKEKSSRKAAEPELMGTLDGTCYPPPPVPRQASPQN LGTPGLLHPQTSPLLHSLVGQHILSVQQFTKDQMSHLFNVAHTLRMMVQKERSLDILKGK VMASMFYEVSTRTSSSFAAAMARLGGAVLSFSEATSSVQKGESLADSVQTMSCYADVVVL RHPQPGAVELAAKHCRRPVINAGDGVGEHPTQALLDIFTIREELGTVNGMTITMVGDLKH GRTVHSLACLLTQYRVSLRYVAPPSLRMPSNVRAFVAARGTKQEEFESIEEALPDTDVLY MTRIQKERFESSQEYEACFGQFILTPHIMTRAKKKMVVMHPMPRVNEISVEVDSDPRAAY FRQAENGMYIRMALLATVLGRF NT seq 6729 nt NT seq  +upstreamnt  +downstreamnt atggcggccctgatgttggaagatgggtcggtcctgcggggccagccctttggggccgct gtgtcgactgccggggaagtggtgtttcaaaccggtatggtcggctaccccgaggctctc actgacccttcctacaaagcacaaatcttagtgctgacatatcctctgatcggcaactat ggcatccccacagatgaagtggatgagttcggtctcagtaagtggtttgaatcctcgggg atccatgtggcaggactggtggtgggagagtgctgtcccacgcccagccactggagtgcc acccgcaccctgcaccagtggctgcaacagcatggcatacctggcctgcaaggagtggat actcgagagctgactaagaagttgcgagagcaagggtctctgctgggaaagctggtccag gatgggacagagccttcagccctgccattcttggaccccaatgcccgtcccctggtgcca gaggtctcaattaaggctccaagggtattcaatgcagggggcactcctcggatccttgct ttggattgtggccttaagtataatcagatccgatgcctgtgccagcgtggagctgaggtc actgtggtaccttgggaccacacattagacagccaggagtatgagggtgtcttcctgagt aatggccctggtgaccctgcctcctatcccagtgtggtatccacactgagccgtgtcata tctgagcctaatccccgacctgtcttcgggatctgtctgggacaccagctgttggcctta gccattggggccaagacatacaagatgagatacggaaaccgaggacataatcagccatgc ttgctggtaggctctgggcgctgctttctgacatcccagaaccatgggtttgctgtggaa acagactcattgccagcaggatggcttccactctttaccaacgccaatgatcgttccaat gaaggcattgtacatgatagcctgccattcttcagtgtccagtttcacccagagcaccaa gctggtccttcagatatggagcttctttttgatatctttctggaaactgtgaaagaagcc acagctgggaaccctgggggctggacagttcgtgagcggctcattgagcgtctctgtccg cctggaattcctacccccggctctgggcttccaccaccacgaaaggttctgattttaggc tctgggggcctctccattggccaagctggagagtttgactactcaggctctcaggcaatt aaggccctaaaggaggaaaacatccagacattgctgatcaaccccaacattgccacagtg cagacttcccaggggctggctgacaaagtctatttccttcccataacacctcactatgta actcaggtgatccgcaatgagcgcccagatggcatattactgacttttgggggccaaaca gctctgaactgtggtgtggagctgaccaaggccggagtattagcgcggtatggggtccgg gtcctgggcacacctgtggaaaccattgaactgactgaagatcggcgtgcctttgcctcc aggatggcagagattggagaacatgtggcccccagtgaggcggctagttctcttgaacag gcccaagcagctgctgagcggctggggtatccagtgctggtgcgtgcagcctttgccctg ggtggcctgggctctggctttgcctctaacagggacgagctctctgctcttgtggctccc gcttttgcccataccagccaggtgctggtagacaagtccctgaagggatggaaggagatt gaatatgaggtggtgagagatgcctatggcaactgtgtcacggtgtgtaacatggagaat ttggacccattgggcatccatactggtgagtccatagtggtggctccaagccagacgctg aatgacagggaataccagctcctgcggcagacagccatcaaggtgacgcagcaccttgga attgttggcgagtgcaacgtgcagtatgcattgaaccccgaatccgagcagtattacatt attgaagtgaatgccaggctctcccgcagctccgccctggccagtaaggccacaggttat ccactggcctatgtggcagccaaactagctctgggcatccctctgcctgagctcaggaac tccgtgacagggggaacagcagcctttgaacccagcctggattactgtgtggtgaagatc cctcgctgggacctcagcaagttccttcgtgtcagcacaaagatcgggagctgcatgaag agcgttggtgaagttatgggcattgggcgttcttttgaggaggccttccagaaggctctt cgcatggtggatgagaactgtgtgggctttgatcacacagtaaagccggtcagtgatatg gagttggagacaccaactgataagcggatctttgtggtggcagctgctctgtgggctggc tattcggtggagcggctgtaccaactcacgcgcatcgaccgctggttcctgcaccggatg aagaggattatagcacatgcccagctgctggaacagcatcgtggacagcctttgccccca gacctgctgcaccaggccaagcgccttggcttctcagacaagcagattgcccttgctgtt ctgagcacagagctggctgttcgcaagctgcgtcaggaactggggatctgcccggcggtg aaacagattgacacagttgcagctgagtggccagcccagacaaattatttgtacctgaca tactggggaaccacgcacgacctcacctttcgaacgccacacgtcctggtccttggctct ggcgtctaccgtataggctccagcgttgagtttgactggtgtgctgtgggctgcatccgg cagctccgaaagatgggatataagaccatcatggtgaactacaacccagagacagtcagc actgattatgacatgtgtgaccgactctactttgatgagatctcttttgaggtggtgatg gacatctatgagctagagaaccctgaaggcgtgatcctgtccatgggtgggcagctgccc aacaacatggccatggctttgcatcggcagcagtgccgggtgctgggcacttctccggaa gccatcgactcagctgagaaccgtttcaaattctcccggctcctagataccattggtatc agccagcctcagtggagggagctcagtgacctagagtctgctcgccagttctgccagacg gtggggtacccctgcgttgtgcgcccctcctatgtgctaagcggcgctgctatgaatgtg gcctacaccgatggggacctggagcgtttcctgagcagtgcggcagccgtctctaaggag caccctgtggtcatctctaagttcatccaggaggccaaggagattgacgtggatgctgtg gcccgtgatggtgtggtggcagccattgccatctctgagcatgtggagaatgcaggtgta cattcaggtgatgccacgctggtgaccccacctcaagacatcactgccaaaaccctggag cggattaaagccatcgtgcacgctgtgggccaggagctgcaggtcacaggacccttcaat ctgcagctcattgccaaggatgaccaactgaaagtcatcgaatgcaacgtgcgtgtctct cgctccttccctttcgtctccaagacacttggtgtggacctagtagcactggccacccgg gtcatcatgggggaagaagtggaacctgtggggctcatgactggctccggagtcgtgggg gtgaaggtccctcagttctcgttttcccgtctggcgggtgctgatgtggtgttgggtgtg gagatgaccagtaccggggaagtggctggctttggggagagccgctgcgaggcatacctc aaggccatgctaagcactggctttaagatccccaagaagaacatcttgctgaccattggc agctataagaacaaaagtgagctgctcccaaccgtgcggctgctggagagccttggctac agcctttacgccagtctgggcactgctgacttctatacggagcacggcgtcaaggtaaca gctgtggactggcactttgaggaggcagtggatggtgaatgcccaccacagcgaagcatc ttggagcagctggctgagaatcactttgaactagtgataaacctatcgatgcgtggggct gggggccggcgtctttcttccttcgtcaccaagggctaccgcacccggcgcctggctgct gacttctccgtgcccctcatcattgatatcaagtgcaccaaactgtttgtggaggcacta ggccagattgggccagcccctcctttgaaggtgcacgttgactgtatgacctcccaaaag ctcgtgcgactacctggattaattgacatccatgtgcaccttcgggaaccagggggcaca cacaaggaggactttgcctcaggcacggctgctgccctggctgggggcattactatggta tgcgccatgccaaacacccggccccccatcattgatgcaccagccctggccctggcccag aagctggcagaagctggtgcccgctgtgactttaccttatttctcggagcctcgtcagaa aatgcagggaccctgggtgctgtggctgggtctgctgctgggttaaagctctacctcaac gagaccttctctgagcttcggttggacaatgtggcccagtggatggagcactttgagaca tggccatcccacctccccatcgtggcccacgcagagaggcagaatgtcgctgccatcctc atggtggcccaactgacccagagatcagtacacatatgtcacgtggctcggaaggaggag atcctgctgattaaagctgcaaaggcacgggggctgccagtgacttgtgaggtggcaccc caccatctatttctgagctgcgatgacctggaacgcttggggccagggaagggggaggtc cggccggagcttgggtcccgccaggacgtggaggccctatgggagaacatggctgtcatc gactgcttcgcctcagaccatgcccctcacaccttggaggagaagtgtgggccccggcct ccccctggcttcccagggctggaaaccatgctgccactgctgctgacagcagtcagtgag ggccggctgagtctggatgacctgctgcagcggctgcaccacaatccccgccggatcttc cacctgcctccgcaggaggacacctatgtggaggtggatctggagcacgaatggaccatc cccagccacatgcccttctccaaggcgcactggacaccctttgaagggcagaaggtgaag ggcaccgtccgccgtgtggtcctccgaggagaggtggcctatatcgacgggcaggtcttg gtgcccccgggctatggacaggatgtccgcaagtggcctcagggaactgttccccagctg gcacccccagcccctgccgccagtgagatcaccacgacgcctgagagaccccgtcgggca gtcccagggcttcctgatggccgcttccacctgccaccccgaattcaccgagcctctgat ccaggtctgccagctgtgttcctccgcccgggagctgggatcccacggggcagcagaacg tgggctgaggagccaaaggaaaagtcgtctcggaaggcagctgagccagagctgatggga actcttgatggcacctgctaccctccaccaccagtacctagacaggcgtcaccccagaac ctggggacccctggcctgctgcacccccagacctcacccctgctgcactcattagtgggt caacatatcctgtctgtccagcaattcaccaaggatcagatgtctcacctgttcaatgtg gcacacacgctgcgtatgatggtacagaaggagcgaagcctcgacatactcaaggggaag gtaatggcctccatgttctacgaggtgagcacacgcaccagcagctcctttgctgcagcc atggcccggctggggggcgctgtgctcagcttctcagaagccacatcttcggtccagaag ggtgaatccctggctgactcagtgcagaccatgagctgctatgccgacgtcgtcgtgctt cggcatccccagcctggagcagtggagctggcagccaagcactgccggaggccagtgatc aatgctggggatggggttggagagcatcccacccaggccctgctggacatcttcaccatc cgggaggagcttgggactgtcaatggcatgacgatcacaatggtgggggacctgaagcat ggacgcacagtgcattctctggcctgcctgctcacccagtaccgtgtcagcctgcgttat gtggcccctcccagcctgcgcatgccatccaatgtgcgggcctttgtggcggcccgtggc accaagcaggaggaatttgagagcattgaggaagccctgcccgacactgatgtgctctac atgactcgaatccagaaggaacgctttgagtctagccaggagtatgaagcttgctttggc cagttcatcctcactccccacatcatgacacgggccaagaagaagatggtggtgatgcac ccaatgcctcgagtcaatgagatcagtgtggaggtggactcagacccccgagcagcctac ttccgccaggccgagaatggcatgtacatacgcatggctctgttagccactgtgctgggc cgcttctag

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