Canis lupus familiaris (dog): 483021
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Entry
483021 CDS
T01007
Symbol
ALK
Name
(RefSeq) ALK tyrosine kinase receptor isoform X2
KO
K05119
anaplastic lymphoma kinase [EC:
2.7.10.1
]
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa05200
Pathways in cancer
cfa05223
Non-small cell lung cancer
cfa05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
483021 (ALK)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
483021 (ALK)
09162 Cancer: specific types
05223 Non-small cell lung cancer
483021 (ALK)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
cfa01001
]
483021 (ALK)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
cfa04090
]
483021 (ALK)
Enzymes [BR:
cfa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
483021 (ALK)
Protein kinases [BR:
cfa01001
]
Receptor tyrosine kinases (RTK)
ALK family
483021 (ALK)
CD molecules [BR:
cfa04090
]
Proteins
483021 (ALK)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
MAM
ALK_LTK_GRD
Ldl_recept_a
FXa_inhibition
Motif
Other DBs
NCBI-GeneID:
483021
NCBI-ProteinID:
XP_038308902
Ensembl:
ENSCAFG00000005297
VGNC:
37802
LinkDB
All DBs
Position
17:complement(22797195..23482846)
Genome browser
AA seq
1632 aa
AA seq
DB search
MGSVGLLGLLLLRLSVTASGSGAGTGSGTGSGTGTGTGQLVGSPATGPALQPREPLSYSR
LQRKSLAVDFVVPSLFRVYARDLLLPPWSSSEPRAGWTEARGSLALDCAPLLRLLGPPPG
VSWAEGASSPAPAQARTLTRVLKGGSVRKLRRAKQLVLELGEEAILEGCVGPSPEEVTAG
LLQFNLSELFSWWIRHGEGRLRIRLMPEKKASAVGREGRLSAAIRASQPRLLFQILGTGH
SSLESPTSLPSPPPDPFAWNLTWIMKDSFPFLSHRSRYGLECSFDFPCELEYSPPLHDLG
NQSWSWRRVPSEEASQMDLLDGPETEHSKEMPRGSFLLLNTSANSKHTILSPWMRSSSEH
CKLAVSVHRHLQPSGRYVAQLLPHNEPGREILLVPTPGKHGWTVLQGRIGRPENPFRVAL
EYISSGNRSLSAVDFFALKNCSEGTSPGSKMALQSSFTCWNGTVLQLGQACDFHQDCAQG
EDEGQLCSQLPAGFYCNFENGFCGWSQGILTPHNPRWQVRTLKDARVQDHRGHALSLSTT
DVPTSESATVTSATFPAPMKNSPCEASLAWEVHGIFRGKSPFGLVENKTGRNKQMRLAWY
LYAHQGLSWEWPHRLPIIEHSDRFWLQIVAWWGQGSRATVAFDNISISLDCYLTISGEEK
MLQNTAPKSRNLFERNPNKDPRPWENTRETPVFDPTVHWLFTTCGASGPHGPTQAQCNNA
YRNSNLSVVVGSEGPLKGIQTWKVPATDTYSISGYGAAGGKGGKNTMMRSHGVSVLGIFN
LEKGDTLYILVGQQGEDACPSTNRLIQKVCIGENNVIEEEIRVNRSVHEWAGGGGGGGGA
TYVFKMKDGVPVPLIIAAGGGGRAYGAKTDTFHPERLENNSSVLGLNGNSGAAGGGGGWN
DNTSLLWSGKSLLEGATGGHSCPQAMKKWGWETRGGFGGGGGGCSSGGGGGGYIGGNAAS
NNDPEMDGEDGVSFISPLGILYTPALKVMEGHGEVNIKHYLNCSHCEGDECHMDPESHKV
ICFCDHGTVLAEDGVSCIVSPTPEPHLPLSLVLSVVTSALVAALVLAFSGIMIVYRRKHQ
ELQAMQMELQSPEYKLSKLRTSTIMTDYNPNYCFAGKTSSISDLKEVPRKNITLIRGLGH
GAFGEVYEGQVSGVPSDPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIG
VSLQALPRFILLELMAGGDLKSFLRETRPRPNQPSSLAMLDLLHVAQDIACGCQYLEENH
FIHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEG
IFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQ
CWQHQPEDRPNFAIILERIEYCTQDPDVINTALPVEYGPLMEEEEKVPMRPQDPEGIPPL
LVSPPQAKREEGPDPAAPPPLPSTSSGKAAKKPTAAELSGRVTRGPAVEGGHVNMAFSQS
NPASELHKVQGSRNKPTSLWNPTYGSWFTEKPTKKNNPPATKGHHDRGNLGREGSCTVPP
NVAAGRLPGASLLLEPSSLTASMKEVPLFRLRHFPCGNVNYGYQQQGLPFEGTTAPGSSQ
YEDALLKTPPGP
NT seq
4899 nt
NT seq
+upstream
nt +downstream
nt
atgggatccgtagggctcctagggctgctgctgctgcggctctcagtgacagcctcgggc
tccggggccgggaccgggagcgggaccgggagcgggaccgggaccgggaccggccagctc
gtgggttcacccgccacggggccggctctgcagcctcgggagccgctcagctactcacgt
ctgcagaggaagagcctggcggtggactttgtcgtgccctcgctcttccgcgtctacgcc
cgggacctgctgctgccgccttggtcctcctcggagcccagggccggctggacggaggcg
cgcggctccctggccctcgactgcgccccgctgcttcggctgctggggccaccgcccggg
gtctcctgggccgaaggcgccagctcgccggccccggcccaggctcggacgctgaccagg
gtgctgaagggcggctcggtccgcaagctccgacgcgccaagcagctggtgctggagctg
ggagaggaggcgatccttgagggctgcgtcgggccctcccccgaggaggtgactgcggga
ctgctccagttcaacctcagcgagctgttcagctggtggattcgccacggcgaaggacgg
ctgaggatccgcctgatgcctgagaagaaggcttcggcagtgggcagagagggaaggctg
tccgcggcgatccgcgcctcccagccccgccttctcttccagatcttggggaccggtcac
agctccttggaatccccaacaagcctgccttctcctcctcctgatccttttgcatggaat
ctgacctggataatgaaagattccttccctttcctgtctcatcgcagtcgatatggtctg
gagtgcagctttgactttccctgtgagctggagtattccccgcccctacacgaccttggc
aaccagagctggtcctggcgccgcgtcccctctgaggaggcctcccagatggacctgttg
gatgggcctgagacagagcactccaaggagatgcccagaggctctttcctcctcctcaat
acctcagcaaactccaagcacaccatcctgagcccgtggatgaggagcagcagtgagcac
tgcaagctggctgtctccgtgcacaggcatctgcaaccttctgggaggtacgtcgcccag
ctgctgccccacaacgagcctggaagagagatcctcctggtacccactccaggaaagcat
ggttggacagtgctccagggaagaattgggcgcccagagaatcccttccgagtggccctg
gaatacatctcgagtggcaaccgaagcttgtctgcagtggacttctttgccctgaagaac
tgcagtgaaggaacatccccaggctccaagatggccttgcagagctccttcacctgctgg
aatgggacggtgctccagctaggccaggcctgtgacttccaccaggactgcgcccaggga
gaagacgagggccagctgtgcagtcaactccctgctggcttttactgcaacttcgagaat
ggcttctgtggctggagccagggcatactcacaccccacaacccccggtggcaggtcagg
actctgaaggatgcccgggtccaggatcatcgaggccacgccctgtcgctcagcaccact
gacgtccctacttctgaaagtgctacagtgaccagtgctacgtttcctgccccaatgaag
aactctccatgtgaggcaagtcttgcttgggaagttcatggtatctttaggggaaagtct
ccttttgggctggtggaaaacaaaacgggaaggaacaaacaaatgagacttgcctggtac
ctatatgcacatcagggactctcttgggagtggccccacaggcttcccatcattgaacac
agtgataggttctggctgcagattgttgcgtggtgggggcaaggatccagagccaccgtg
gcttttgacaatatctccatcagcctggactgctacctcaccatcagtggagaggagaag
atgctacagaatacagcacccaaatcaagaaatctatttgagagaaacccaaacaaggac
ccaagaccctgggaaaatacaagagagacccccgtctttgaccctacagttcactggctg
ttcaccacgtgtggggccagtgggccccatggccccacacaggcccagtgtaacaacgcc
taccggaattccaacctgagcgtggtggtggggagcgagggccccctgaagggcatccag
acctggaaggtgccagccaccgacacctacagcatctcaggctacggagctgctggtggg
aaaggcgggaagaacaccatgatgcggtcccacggtgtgtctgtgctgggcatcttcaac
cttgagaaaggcgacacattgtacatcttggttgggcagcagggggaagacgcctgcccc
agcacaaaccgattaatccagaaagtctgcattggagagaacaacgtgatagaagaagaa
atccgcgtgaacagaagtgtgcatgagtgggcaggagggggcggaggaggaggtggagcc
acctacgtatttaagatgaaggacggcgtgccagtgcccctgatcattgcagccggcggg
ggcggcagggcctacggcgccaagacagacacgttccacccagagagactggagaataac
tcctcggtcctggggctgaacggcaactccggagcggcaggtggtggaggtggctggaat
gataatacttccttgctctggtctggaaaatctttgctggagggtgccaccggaggacat
tcctgcccccaggccatgaagaagtgggggtgggagacaagagggggtttcggagggggt
ggcggggggtgctcctcaggtggaggaggcggaggatatataggcggcaacgcggcctca
aacaatgaccccgagatggacggggaggacggggtttccttcatcagtccgctgggcatc
ctgtacaccccagctttaaaagtgatggagggccacggggaagtgaatattaagcattat
ctaaactgcagccactgtgagggagacgagtgccacatggacccagaaagccacaaggtc
atctgcttctgtgatcacgggacagtgctggctgaggatggcgtctcctgcatcgtatcc
cccaccccagagccccacctgccactctcactggtcctgtccgtcgtgacctcagccctc
gtggccgccctggtcctggctttctccggcatcatgattgtgtaccgccggaaacaccag
gagctgcaggccatgcagatggagctccagagccccgagtataagctgagcaagctccgt
acctcgaccatcatgactgactacaaccccaactactgctttgctggcaagacctcgtcc
atcagtgacctgaaggaggtgcctcggaaaaacatcaccctcatccggggactgggccac
ggtgcgtttggggaggtgtatgagggtcaggtgtctggagtgcccagcgacccgagcccc
ctgcaagtggccgtaaagacgctgcctgaggtgtgttctgaacaggacgaactggatttc
ctcatggaagccctgataatcagcaaattcaaccaccagaacatcgtgcgctgtatcggg
gtgagtctgcaagccctgcctcgatttatcctcctggagctcatggcaggaggagacctc
aagtccttcctccgggagacccgccctcgcccgaaccagccttcctccctggccatgctg
gaccttctgcatgtggctcaggacatcgcctgtggctgtcagtatttggaggaaaatcac
ttcatccaccgggacattgctgccagaaactgcctcttaacctgtccaggccctggcaga
gtggccaagattggagactttggaatggcccgggacatctacagagcgagctactaccga
aaaggaggctgtgcaatgctgccagtcaaatggatgcctcccgaggccttcatggaaggg
atctttacctctaaaacagacacctggtcctttggagtgctgctgtgggaaatattttct
cttggatacatgccataccctagcaaaagcaaccaggaagttctggagttcgtcaccagc
ggaggacggatggacccacctaagaactgtcctgggcctgtgtaccggataatgacccag
tgctggcaacatcagcctgaagataggcccaactttgccattattttggagaggattgaa
tactgtacccaggacccagatgtgatcaacactgctttgcccgtagagtatggcccactc
atggaagaggaggagaaggtgcccatgaggccccaagaccctgagggaattcctcctcta
ctcgtctctcctccacaagctaaacgggaggaagggccagatccagctgccccgcctccc
ctgccttccacttcctctggcaaagctgccaagaagcccacggctgcggagctctctggt
cgagtcactaggggaccagctgtggaaggaggacacgtgaacatggcattctctcagtcc
aacccagcgtcagagctgcacaaagtccagggatccagaaacaaacccaccagcctatgg
aacccaacttacggctcatggtttacagagaaacccaccaaaaagaacaatcctccagca
acgaaggggcaccacgacagggggaacctggggcgtgagggaagctgtactgtcccacct
aacgtggcagctggcagactcccaggtgcctctctgctcctagaaccatcctcgctgact
gccagcatgaaggaagtgcctctgttcaggctgcgtcacttcccgtgtggcaacgtcaac
tacggctaccagcaacagggcttacccttcgagggcaccaccgcgcccggaagcagccag
tacgaggacgccctcctgaaaaccccacctgggccctga
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integrated database retrieval system
