KEGG   Canis lupus familiaris (dog): 483028
Entry
483028            CDS       T01007                                 
Symbol
XDH
Name
(RefSeq) xanthine dehydrogenase/oxidase isoform X2
  KO
K00106  xanthine dehydrogenase/oxidase [EC:1.17.1.4 1.17.3.2]
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa00230  Purine metabolism
cfa00232  Caffeine metabolism
cfa00983  Drug metabolism - other enzymes
cfa01100  Metabolic pathways
cfa01232  Nucleotide metabolism
cfa04146  Peroxisome
Module
cfa_M00958  Adenine ribonucleotide degradation, AMP => Urate
cfa_M00959  Guanine ribonucleotide degradation, GMP => Urate
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    483028 (XDH)
  09110 Biosynthesis of other secondary metabolites
   00232 Caffeine metabolism
    483028 (XDH)
  09111 Xenobiotics biodegradation and metabolism
   00983 Drug metabolism - other enzymes
    483028 (XDH)
 09140 Cellular Processes
  09141 Transport and catabolism
   04146 Peroxisome
    483028 (XDH)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:cfa04147]
    483028 (XDH)
Enzymes [BR:cfa01000]
 1. Oxidoreductases
  1.17  Acting on CH or CH2 groups
   1.17.1  With NAD+ or NADP+ as acceptor
    1.17.1.4  xanthine dehydrogenase
     483028 (XDH)
   1.17.3  With oxygen as acceptor
    1.17.3.2  xanthine oxidase
     483028 (XDH)
Exosome [BR:cfa04147]
 Exosomal proteins
  Exosomal proteins of breast milk
   483028 (XDH)
SSDB
Motif
Pfam: MoCoBD_2 MoCoBD_1 FAD_binding_5 Ald_Xan_dh_C Fer2_2 CO_deh_flav_C Fer2
Other DBs
NCBI-GeneID: 483028
NCBI-ProteinID: XP_005630370
Ensembl: ENSCAFG00000005609
VGNC: 48448
LinkDB
Position
17:complement(24694965..24754929)
AA seq 1332 aa
MTADELVFFVNGKKVVEKNADPETTLLAYLRRKLRLSGTKLGCGEGGCGACTVMLSKYDR
FQNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKSRLHPVQERIAKSHGSQCGFCTPGI
VMSMYTLLRNQPEPTIEEIENAFQGNLCRCTGYRPILQGFRTFAKDGGCCGGSRDNPNCC
LNQKKDCSRVILSPSLFNPEEFMPLDPTQEPIFPPELLRLKDVPQKQLCFKGERVTWIQA
STLKELLDLKAQHPEAKLVVGNTEIGIEMKFKNRLFPMIVCPAWIPELNAVEHGLEGISF
GAACPLSIVEKTLHDAVNKLPAYKTEVFKGVLEQLRWFAGKQVKSVASIGGNIINASPIS
DLNPVFMASEAKLTIVSRGIKRTVRMDHTFFPGYRKTLLAPEEILLSIEIPYSREGEFFS
AFKQASRREDDIAKVTSGMRVLFHPGTAQVKELALCYGGMDDRTISALKTTRKQVENLWN
EDLLQNVCAGLAEELKLSPDAPGGMVDFRRTLTLSFFFKFYLTVLQKLERGNLENCGKLD
PTYASATLLFQKDPPANVQLFQEVPEGQSEEDMVGRPLPHLAAAMQASGEAVYCDDIPRY
ENELSLRLVTSTRAHAKIKSIDTSEAEKVPGFVCFLSFNDVPGSNKTGIFNDETIFAEDE
VTCIGHIIGAVVTDTPEHAQRAAQGVKITYEELPAIITIEDAIKNNSFYGSELKIEKGEL
TKGFSEADNVVSGEVYIGGQEHFYLETHCTIAVPKGEEGELELFASTQNTMKTQAFVANM
LGVPINRILVRVKRMGGGFGGKETRSTLVSTVVALAAYKTGRPVRCMLDRDEDMLITGGR
HPFLAKYKVGFMKTGKVVALEVEHYSNAGNTLDLSQSIMERALFHMDNCYKIPNIRGTGR
LCKTNLPSNTAFRGFGGPQGMLIAEYWMSEVAMTCGLPAEEVRRKNMYKEGDLTHFNQKL
EGFTLSRCWEECLASSQYHARKSEVDKFNEENYWKKRGLCIIPTKFGISFTLSFLNQAGA
LIHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSPTAA
SVSADINGQAVYEACKTILKRLEPFKKKNPSGSWEDWVIDAYENTVSLSATGFYRTPNLG
YSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAF
VQGLGLFTLEELHYSPEGSLQTRGPSTYKIPAFGNIPTEFRVSLLRDCPNKKAIYASKAV
GEPPLFLAASVFFAIKDAVRAARARNSDCKTKLFRLDSPATPEKIRNACVDEFTTLCVTG
IPENCKPWSVRV
NT seq 3999 nt   +upstreamnt  +downstreamnt
atgacagctgacgaattggttttcttcgtgaatggcaaaaaggtggtggagaaaaatgca
gatccagaaacaacccttttggcctacctgagaagaaaattgcggctgagtgggaccaag
ctgggctgtggagaagggggctgtggggcttgtaccgtgatgctttccaagtacgatcgt
ttccagaacaagatcgtccacttttctgccaatgcctgcctggcccccatctgctctttg
catcatgttgctgtgactaccgtggaaggaataggaagcaccaaatccaggctgcatcct
gtgcaggagagaattgccaaaagccatggctcccagtgtgggttctgcacccctggcatc
gtcatgagcatgtacacgctgctccggaaccagcctgagcccaccattgaggagatcgag
aacgccttccaaggaaacctgtgccgctgcacgggctacagacccatcctccagggcttc
cggaccttcgccaaggatggtgggtgctgtggagggagcagggacaaccccaactgctgc
ctgaaccagaagaaagactgctcacgggtcattctctcgccatctttgttcaacccagaa
gagttcatgccactggaccccacccaggagcccatcttccctccagagctgctgaggctg
aaagatgttcctcagaagcagctgtgttttaaaggcgagcgagtgacctggatccaggcc
tccaccctgaaggagctgctggacctcaaagcccagcaccccgaggccaagctggtggtg
gggaacacggagattggcattgagatgaagttcaagaacaggctgtttcctatgattgtc
tgcccagcctggatccctgagctgaatgcagtggagcacggactggagggtatctccttt
ggagctgcttgccccttgagcattgtggaaaagacactgcatgatgccgttaacaaactt
cctgcctacaaaacagaggtgttcaaaggtgtcctggagcagttgcgctggtttgctggg
aagcaggtcaagtctgtggcgtccattggagggaacatcatcaatgccagccccatctct
gacctcaatcctgtgttcatggccagtgaggccaagctgaccatcgtgtccagaggcatc
aagagaacagttcggatggaccacaccttcttccctggctacaggaagaccctactagcc
ccggaggagatcctgctttccatcgagatcccctacagcagggagggtgagtttttctca
gcattcaagcaggcctctcggagggaagatgacatagccaaggtgaccagtggcatgaga
gtcctgttccatccaggaaccgcacaggtaaaggagctggccctttgctatggcggaatg
gatgacagaaccatctcagctctcaagaccacacggaagcaggtggaaaatttatggaat
gaggatctgctgcagaacgtgtgtgcaggcctggcagaggagctgaagctgtcccccgat
gcccctggcggcatggtggactttcggcggaccctcaccctcagcttcttcttcaaattc
tacctgacagtgcttcagaaattagagagagggaacttagaaaattgtgggaagctggac
cccacctatgccagtgccaccttactctttcagaaagaccctccagccaacgtccagctc
ttccaagaggtgcctgagggtcagtctgaagaggacatggtgggccggcccctgccccac
ctggctgcggccatgcaggcctccggggaggctgtgtactgtgatgacatccctcgctac
gagaacgagctgtccctccgactggtcaccagcacccgggcccatgccaagatcaagtcc
atagatacttcagaagctgagaaggtgccagggttcgtttgctttctctcttttaatgat
gttcctgggagtaataaaactggaatttttaacgatgaaacaatctttgcagaggatgag
gtgacttgtattgggcacatcattggtgctgtggtcaccgacactccagaacatgcacag
agagctgctcagggggtgaaaatcacctatgaagaacttccagccattattacaattgag
gatgctataaaaaacaattccttttatgggtctgagctgaagatcgagaagggagaactc
acgaaggggttttcagaagcagacaacgttgtttcaggcgaagtgtacataggtgggcaa
gagcacttctacctggagactcactgcaccatcgccgtcccgaaaggtgaggaaggggag
ttggagctctttgcgtctacacagaacaccatgaagacccaggccttcgtggcaaacatg
ttgggggttccaataaaccggattttggtccgagtgaagagaatgggaggaggctttgga
gggaaagagacccggagcaccctggtgtccacggtagtagccctggctgcatacaagact
ggccgccctgtgcgctgcatgctggatcgtgatgaggacatgctgataactggtggcaga
catcccttcttagccaaatacaaggttggcttcatgaagactgggaaggtggtggctctg
gaggtggagcactacagcaatgctgggaataccctggatctctcccagagtataatggaa
cgagccctattccacatggacaactgctataaaatacccaatatccggggcactgggcgg
ctctgcaagaccaacctgccctccaacacggccttccggggctttgggggaccccagggc
atgctcattgctgagtattggatgagtgaagtcgcgatgacctgtgggctgcctgcagag
gaagtgcggaggaaaaacatgtataaggaaggggacctgacacacttcaaccagaagctt
gaggggttcaccttgtccaggtgctgggaggaatgcctagcaagctctcagtatcacgcc
cggaagagtgaggttgacaagttcaatgaggagaattattggaagaagagaggattgtgt
ataattcctaccaagtttggaataagcttcactctttcttttctgaatcaggcaggagcc
ctgattcatgtgtacacagatggctctgtgctgctgacccatgggggcactgagatgggc
caaggcctacacaccaagatggtccaggtggccagcagagctctgaaaatccctacctct
aagatttacatcagtgagacaagcacgaacactgtgcccaacacctctcccacggccgcc
tccgtcagcgctgacatcaatggacaggctgtctatgaagcttgtaagaccatcctgaaa
agactggagcccttcaagaaaaagaatcctagtggctcctgggaagattgggtcatagac
gcctacgagaacacagtgagcttgtctgcgactgggttttataggacacccaaccttggc
tacagctttgagactaactcggggaatcccttccactacttctcctatggggtggcttgc
tctgaagtggagatcgattgcttaaccggggatcacaaaaacctccgtaccgacattgtc
atggatgttggttccagtctgaaccctgccattgatattggacaggtggaaggagcattt
gtgcagggccttggcctcttcaccctggaggagctgcactactccccagaggggagcctg
cagacccgtggccccagcacctataagatccctgcgtttggcaacatccccactgagttc
agagtgtccctgctccgcgactgccccaacaagaaggccatctatgcgtccaaggccgtc
ggggagccgcccctcttcctggcagcctctgtcttctttgccatcaaggacgccgtccgt
gcagctcgtgctaggaactcagattgtaaaacgaagcttttccggctagacagccctgca
accccagaaaagatccgcaatgcctgcgtggacgagttcaccacactgtgtgtcactggc
ataccagaaaactgtaagccctggtcggtgagggtctga

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