KEGG   ENZYME: 1.17.3.2
Entry
EC 1.17.3.2                 Enzyme                                 
Name
xanthine oxidase;
hypoxanthine oxidase;
hypoxanthine:oxygen oxidoreductase;
Schardinger enzyme;
xanthine oxidoreductase;
hypoxanthine-xanthine oxidase;
xanthine:O2 oxidoreductase;
xanthine:xanthine oxidase
Class
Oxidoreductases;
Acting on CH or CH2 groups;
With oxygen as acceptor
Sysname
xanthine:oxygen oxidoreductase
Reaction(IUBMB)
xanthine + H2O + O2 = urate + H2O2 [RN:R02107]
Reaction(KEGG)
Substrate
xanthine [CPD:C00385];
H2O [CPD:C00001];
O2 [CPD:C00007]
Product
urate [CPD:C00366];
H2O2 [CPD:C00027]
Comment
An iron-molybdenum flavoprotein (FAD) containing [2Fe-2S] centres. Also oxidizes hypoxanthine, some other purines and pterins, and aldehydes, but is distinct from EC 1.2.3.1, aldehyde oxidase. Under some conditions the product is mainly superoxide rather than peroxide: RH + H2O + 2 O2 = ROH + 2 O2.- + 2 H+. The mammalian enzyme predominantly exists as an NAD-dependent dehydrogenase (EC 1.17.1.4, xanthine dehydrogenase). During purification the enzyme is largely converted to the O2-dependent xanthine oxidase form (EC 1.17.3.2). The conversion can be triggered by several mechanisms, including the oxidation of cysteine thiols to form disulfide bonds [4,5,7,10] [which can be catalysed by EC 1.8.4.7, enzyme-thiol transhydrogenase (glutathione-disulfide) in the presence of glutathione disulfide] or limited proteolysis, which results in irreversible conversion. The conversion can also occur in vivo [4,6,10].
History
EC 1.17.3.2 created 1961 as EC 1.2.3.2, transferred 1984 to EC 1.1.3.22, modified 1989, transferred 2004 to EC 1.17.3.2, modified 2011
Pathway
ec00230  Purine metabolism
ec00232  Caffeine metabolism
ec00983  Drug metabolism - other enzymes
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K00106  xanthine dehydrogenase/oxidase
Genes
HSA7498(XDH)
PTR470347(XDH)
PPS100986628(XDH)
GGO101138402(XDH)
PON100454383(XDH)
NLE100594931(XDH)
MCC708046(XDH)
MCF102116275(XDH)
CSAB103220539(XDH)
CATY105578407(XDH)
PANU101025208(XDH)
TGE112604828(XDH)
RRO104659929(XDH)
RBB108516631(XDH)
TFN117062505(XDH)
PTEH111546045(XDH)
CJC100414932(XDH)
SBQ101044169(XDH)
CSYR103277239(XDH)
MMUR105884462(XDH)
OGA100964035(XDH)
MMU22436(Xdh)
MCAL110312137(Xdh)
MPAH110335495(Xdh)
RNO497811(Xdh)
MCOC116080025(Xdh)
MUN110557067(Xdh)
CGE100766626(Xdh)
PLEU114696109(Xdh)
NGI103748365(Xdh)
HGL101708017(Xdh)
CPOC100731391(Xdh)
CCAN109701710(Xdh)
DORD105983773(Xdh)
DSP122122529(Xdh)
NCAR124963278
OCU100144327(XDH)
OPI101525501(XDH)
TUP102477455(XDH)
CFA483028(XDH)
VVP112933009(XDH)
VLG121491027(XDH)
AML100465942(XDH)
UMR103671606(XDH)
UAH113240940(XDH)
UAR123799862(XDH)
ELK111154104
LLV125108404
MPUF101682887(XDH)
ORO101376175(XDH)
EJU114219619(XDH)
ZCA113937113(XDH)
MLX118007742(XDH)
FCA105259797 493692(XDH)
PYU121044311(XDH)
PBG122497284(XDH)
PTG102969928
PPAD109261405 109262396(XDH)
AJU106967886(XDH)
HHV120227484(XDH)
BTA280960(XDH)
BOM102264420(XDH)
BIU109565958(XDH)
BBUB102406968(XDH)
CHX100861280(XDH)
OAS780499(XDH)
ODA120851644(XDH)
CCAD122441533(XDH)
SSC100515259(XDH)
CFR102523581(XDH)
CBAI105063890(XDH)
CDK105095605(XDH)
VPC102535276(XDH)
BACU103004564(XDH)
LVE103084498(XDH)
OOR101284574(XDH)
DLE111174909(XDH)
PCAD102980160(XDH)
PSIU116763997(XDH)
ECB100054601 100054641 100054688
EPZ103547521(XDH) 103561661 103567354
EAI106847214 106847249 106847250
MYB102262378(XDH)
MYD102773370(XDH)
MMYO118669132(XDH)
MLF102441222(XDH)
MNA107541765(XDH)
HAI109395899
DRO112297809(XDH)
SHON119001296(XDH)
AJM119050452(XDH)
PDIC114499974(XDH)
PHAS123813617 123822476(XDH)
MMF118630749(XDH)
RFQ117033444 117033445
PALE102884734(XDH)
PGIG120621538(XDH)
PVP105299158(XDH)
RAY107505738(XDH)
MJV108404078(XDH)
TOD119259422(XDH)
SARA101546315(XDH)
LAV100672640(XDH)
TMU101349074
DNM101430447(XDH)
MDO100031481(XDH)
GAS123233504(XDH)
SHR100933358(XDH)
PCW110198166(XDH)
OAA100073679 100078272 100078307 100078335 100078370 100085630 100681543 114806406
GGA396025(XDH)
PCOC116235286(XDH)
MGP100544067(XDH)
CJO107310773(XDH)
NMEL110395607(XDH)
APLA101799192(XDH)
ACYG106031596(XDH)
AFUL116487376(XDH)
TGU100222890(XDH)
LSR110473976(XDH)
SCAN103821303(XDH)
PMOA120505896(XDH)
OTC121346920(XDH)
PRUF121357042(XDH)
GFR102040336(XDH)
FAB101819038(XDH)
PHI102106931(XDH)
PMAJ107201507(XDH)
CCAE111926289(XDH)
CCW104685575(XDH)
ETL114073409(XDH)
ZAB102067540(XDH)
FPG101918653(XDH)
FCH102052812(XDH)
CLV102092037(XDH)
EGZ104134615(XDH)
NNI104019267(XDH)
ACUN113478412(XDH)
TALA104360092(XDH)
PADL103925004(XDH)
ACHC115350051(XDH)
AAM106482734(XDH)
AROW112963417(XDH)
NPD112954835(XDH)
DNE112980054(XDH)
ASN102374197(XDH)
AMJ102564016(XDH)
CPOO109319793(XDH)
GGN109304651(XDH)
PSS102461631(XDH)
CMY102945230(XDH)
CPIC101953114(XDH)
TST117874524(XDH)
CABI116835408(XDH)
MRV120400858(XDH)
ACS100566790(xdh)
PVT110087557(XDH)
SUND121924204(XDH)
PBI103056546(XDH)
PMUR107297206(XDH)
TSR106538731(XDH)
PGUT117671370(XDH)
VKO123026876(XDH)
PMUA114594599(XDH)
ZVI118083239(XDH)
GJA107112582(XDH)
STOW125439847(XDH)
XLA108716095(xdh.L) 108717383(xdh.S)
XTR100497499(xdh)
NPR108796807(XDH)
RTEM120937824(XDH)
BBUF120999630(XDH)
BGAR122936166(XDH)
DRE560486(xdh)
SRX107733164 107752765
SANH107674096 107697780(xdh)
SGH107592779 107594783
CCAR109084316 109107555(xdh)
CAUA113060638 113091723 113117257
PPRM120481705(xdh)
MAMB125269090(xdh)
IPU108269840(xdh)
PHYP113533982(xdh)
SMEO124390465(xdh)
TFD113651189(xdh)
AMEX103031284(xdh)
EEE113583665(xdh)
TRU101073141(xdh)
TNGGSTEN00012569G001
LCO104938633
CGOB115004954(xdh)
ELY117250086(xdh)
PLEP121962722
SLUC116064651(xdh)
GAT120817414
PPUG119212539(xdh)
MSAM119884977 119906674(xdh)
CUD121506507
MZE101478907(xdh)
ONL100706331(xdh)
OAU116325034(xdh)
OLA101162508(xdh)
OML112156738(xdh)
XMA102231285(xdh)
XCO114140507(xdh)
XHE116715626(xdh)
PRET103481416(xdh)
PFOR103150941(xdh)
PLAI106950380(xdh)
PMEI106910105(xdh)
GAF122826981(xdh)
CVG107104320(xdh)
CTUL119791561(xdh)
GMU124861394(xdh)
NFU107384577(xdh)
KMR108251278(xdh)
ALIM106531265(xdh)
NWH119428826(xdh)
AOCE111587270(xdh)
CSEM103389795(xdh)
SSEN122765558(xdh)
HHIP117772694(xdh)
LCF108877173(xdh)
SDU111235538(xdh)
SLAL111646897(xdh)
XGL120797967(xdh)
HCQ109510392(xdh)
BPEC110166494(xdh)
SASA100380763(xdh)
OTW112262239(xdh)
OMY110498216(xdh)
OGO124001236(xdh)
ONE115118700
SALP112071841
SNH120059710(xdh)
ELS105031569(xdh)
SFM108923027(xdh)
PKI111834729(xdh)
AANG118223068
LOC102695048(xdh)
PSPA121315990(xdh)
ARUT117402411(xdh)
CMK103182679 103187630(xdh)
RTP109913754(xdh) 109930681
BFO118404231 118416437 118422838 118425672 118425674 118426141
BBEL109467339 109470035 109472408 109484060
CIN100181207 100181350 100181761
SCLV120338173 120340015 120342206 120342361 120342964 120343470
SPU115918813 576712 585597 588814 756453
APLC110973665 110973746 110976709 110976819 110981399
SKO100367784 100369948 100370093 100370241 100371837 100374085 100374238 100374711 102807482 102808189
DMEDmel_CG18516(AOX4) Dmel_CG18519(AOX2) Dmel_CG18522(AOX1) Dmel_CG6045(AOX3) Dmel_CG7642(ry)
DER6553059 6553130 6553131 6553132 6553738
DSE6606230 6606231 6606232 6606233 6606582
DSIDsimw501_GD18875(Dsim_ry) Dsimw501_GD20335(Dsim_GD20335) Dsimw501_GD20336(Dsim_GD20336) Dsimw501_GD20337(Dsim_GD20337) Dsimw501_GD20338(Dsim_GD20338)
DYADyak_GE26236(Dyak_ry) Dyak_GE26365 Dyak_GE26366 Dyak_GE26367 Dyak_GE26368
DAN6499278 6499279 6499281 6499282 6499283 6507958
DSR110187649 110191806 110191860 110191876 110191877
DPODpse_GA14970 Dpse_GA14971 Dpse_GA14972 Dpse_GA19318 Dpse_GA20500(Dpse_ry) Dpse_GA24746 Dpse_GA26139
DPE6587207 6590894 6594489 6594490 6594491 6594492 6594493
DMN108153844 108154180 108156882 108156883 108156958 108156959 108160859
DWI6647368 6647369 6647370 6648051
DGR6563012 6563013 6563145 6563146 6563390 6563581 6563583 6570992
DMODmoj_GI10152 Dmoj_GI22594 Dmoj_GI23360(Dmoj_Xdh)
DAZ108616762 108620959
DNV108657347 108660187 108660287
DHE111593322 111594552 111604826 111604856
DVI116650298 6629800 6632895 6633223 6633224
CCAT101450812 101450997 101454827(Xdh) 101456672
BOD106616535 106619481 106623490 106623495
MDE101897226 101898542 101900980 101901154 101901324
SCAC106082379 106082452 106082772 106082773 106082775 106087981 106088014
LCQ111674521 111674526 111681636
AGAAgaP_AGAP005636 AgaP_AGAP005637 AgaP_AGAP005638 AgaP_AGAP006220 AgaP_AGAP006221 AgaP_AGAP006224 AgaP_AGAP006225 AgaP_AGAP006226 AgaP_AGAP007918
ACOZ120951441 120951442 120952638 120953808 120953811 120953812 120953813 120953814 120956350 120956351
AARA120894535 120897231 120902756 120902793 120902945 120902946 120907621 120908477 120908478
AAG23687731 5564528 5567568 5573274 5573280 5573282 5573294 5573295 5573296 5573297 5575671
AALB109398275 109403004 109403005 109403053 109403074 109408659 109408662 109408663 109408675 109408692 109408694 109408695 109413809 109421851 109421858 109429794 115268902
CQUCpipJ_CPIJ004121 CpipJ_CPIJ004365 CpipJ_CPIJ013919 CpipJ_CPIJ013920 CpipJ_CPIJ013921 CpipJ_CPIJ013922 CpipJ_CPIJ013934 CpipJ_CPIJ016888 CpipJ_CPIJ016889 CpipJ_CPIJ017835 CpipJ_CPIJ017836
CPII120412669 120423364 120423365 120424639 120424640 120424641 120424642 120424648 120426098 120426101 120430097 120430099 120430127 120430136 120432483
CNS116338360 116341334 116349268
AME724718 724933
ACER107992582 108003909
ALAB122716316 122717249
BIM100741462 100745073
BBIF117204638 117214341
BVK117242522 117243463
BVAN117161180 117163355
BTER100645396 100650366
BPYO122571097 122576656
CCAL108630201 108630202
OBB114872175 114878382
MGEN117218864 117227018
NMEA116432714 116433044
CGIG122397030 122401038
SOC105194140 105194920 105194921 105195075 105200154
MPHA105828703 105828704 105831295 105835087 105835225
AEC105147363 105150087 105150088 105150095
ACEP105621442 105621443 105621444 105624849
PBAR105428843 105428975 105433344
VEM105560955 105565564 105570086 105570087
HST105181992 105181993 105187386
DQU106748485 106751775
CFO105254319 105258610
FEX115235679 115237047
LHU105669451 105671669
PGC109853916 109856224
OBO105277675 105285080
PCF106785781 106786804 106790306
PFUC122514548 122520138 122520139
VPS122630437 122634010
NVI100120307 100122636 100123235 100123244 116738587
CSOL105360975 105361160 105362635 105362748
TPRE106650835 106650936 106652196 106652199 106652303
MDL103568824 103577717
CGLO123260022 123267458
FAS105266387 105266485 105270848 105271268
DAM107036813 107036814 107041335 107045032 107045033
AGIF122851194
CCIN107269143 107270342
TCA655982 656059 656621 656938
DPA109536954
SOY115875246 115875264 115885157
ATD109598932 109598934 109599933 109600365 109602553 109602563 109604513 109605896
CSET123314351 123322847 123322850
AGB108904576 108906838 108909767 108909768 108909769
LDC111502823 111508569 111509937 111509938 111514068
NVL108556639 108558270 108564547
APLN108745232 108745235 112906752
PPYR116165573 116176375 116176415 116176470 116176584 116177444
OTU111413388 111425273 111425274
BMOR100126537(Aox2) 100126538(Aox1) 101736569 101738209 101738479 101738607 101738746 101739179 101741112 692751(Xdh1) 692757(Xdh2)
BMAN114244354 114244356 114244361 114244393 114248223 114248644 114248648 114250054 114250056 114250075
MSEX115440452 115440464 115447187 115447190 115447203 115451583 115451584 115451585 115451586 115451588 115452966 115453444 115453445 115453584 115453587 115453828 115453829 115454300 115454344 119188979 119189033 119191151 119191222 119192447
DPLKGM_200223 KGM_204714 KGM_205480 KGM_205813 KGM_205814 KGM_208006 KGM_210883
BANY112045001 112045016 112054404 112054752 112054753 112054754 112054755 112054756 112054759 112054791 112054963 112057810 112057811 112057812 112057839 112057840 112057841 112057856
PMAC106710091 106710107 106710109 106710136 106711951 106714714 106715021 106717766 106717831 106719818 106720051
PPOT106101429 106101431 106101450 106101589 106101627 106101631 106102803 106102857 106106642 106106652
PXU106113607 106113736 106113818 106113820 106113821 106113900 106113906 106116114 106125300 106126443
PRAP110991669 110991684 110991702 110991712 110992974 110992986 110994009 110994024 111002738 123689272
ZCE119832790 119832800 119832806 119832807 119832832 119832842 119833037 119834532 119834570
HAW110370678 110370752 110372104 110372128 110372130 110372133 110372181 110372197 110380988 110380991 110381338 110381339 110381341
TNL113497333 113497732 113503713 113503720 113503722 113503729 113503763 113503779 113503796 113503838 113503843 113503874 113503882 113503884 113503919 113503921 113503932 113503934 113503935 113503936 113503938 113503973 113506576
SLIU111348447 111348462 111353324 111356384 111356385 111356424 111356425 111356552 111356719 111356722 111356789 111356791 111356793 111356887 111356892 111362286 111362287
OFU114354018 114354019 114355388 114355432 114355434 114357816 114357817 114364650 114364654 114364657 114366400
PXY105382860 105383538 105383938 105384208 105389900 105390506 105392377
API100169249
DNX107172284
AGS114119532
RMD113550991
BTAB109038855 109038856 109038857 109043878
DCI103505953 103506383 103506446
CLEC106667598 106667714 106667742 106669696 106669697
HHAL106678177 106678423 106679843 106684762 106685392 106685394 106685395 106689827 112211197
NLU111047233 111048124 111055221 111055387 111056736 111057942 111060901
PHUPhum_PHUM299090
FOC113202160 113208696
ZNE110830577 110831923 110834599
CSEC111862067 111863409 111871103
FCD110842136 110845042 110845123 110846051 110846885 110850366 110850372 110851258 110853954 110856936 110859404 110860745
DPXDAPPUDRAFT_303976 DAPPUDRAFT_308494 DAPPUDRAFT_313254
DMK116932201 116935997
PVM113803334 113807596 113816325 113816330 113818250 113820698 113821249 113822117
PJA122244700 122246368 122253058 122253059 122254912 122257079 122258314 122266166
PCHN125030592 125030783 125042430 125042725 125045715 125045892 125045928 125046051 125047242
HAME121855940 121863052 121873153
PCLA123760653 123761435 123764494 123764597 123769025 123772069
PTRU123502998 123503217 123503640 123506534
HAZT108666840 108669464 108671723 108673679 108676789 108682927
EAF111706059 111707581 111710914 111711437 111711542 111711549 111715053
LSM121122557 121123168 121124867 121129430
CELCELE_F55B11.1(xdh-1)
CBRCBG_21624
NAINECAME_12304
HROHELRODRAFT_110470 HELRODRAFT_77403
LGILOTGIDRAFT_131803 LOTGIDRAFT_142910 LOTGIDRAFT_160669 LOTGIDRAFT_221063 LOTGIDRAFT_226623 LOTGIDRAFT_231915
PCAN112558481 112558482 112558485 112558486 112558487 112558498 112558796 112558798 112558805 112558811 112560136 112560812 112570128 112570129 112570981 112571030
BGT106053189 106054344 106054458 106055410 106056807 106056890 106056891 106059682 106059685 106061888 106062035
GAE121370649 121371427 121371431 121371433 121379110 121381254
HRF124121495 124123849 124123859 124126580 124129232 124129233 124131799 124131800 124131802 124131803 124138159 124138160 124138161 124138163 124138164 124138211 124138597 124138599 124142279 124142280 124142353 124145701 124146369
HRJ124268728 124268729 124268730 124268731 124268793 124268795 124268796 124268798 124280457 124280458 124283166 124283210 124283229 124284107 124290733 124290734
CRG105320492 105320513 105320852 105322104 105338956
MYI110445033 110450249 110456211 110456221 110461878 110465502 110466688
PMAX117314925 117317704 117321650 117324561 117335971 117336390
MMER123523256 123523267 123535767 123535779 123536060 123536061 123544928 123558173 123561824
LAK106150636 106154083 106154084 106155380 106156363 106164024 106165802 106168247 106168374 106168375 106171242 106176707 112042293
NVE5502195 5503264 5505020 5505093 5507602 5517059
EPA110233962 110236355 110236358 110242287
ATEN116292241 116293509 116298401 116306789 116308284
ADF107328902 107337555 107348750 107355055
AMIL114963640 114975650 114975704
PDAM113664414 113669307 113684296
SPIS111323187 111323199 111324914 111344894
DGT114519687 114519708 114523124 114534119 114534120 114539283
XEN124443144
TADTRIADDRAFT_26553 TRIADDRAFT_26606 TRIADDRAFT_27111 TRIADDRAFT_57138
AQU100631413 100631668 100631741 100632280 100636568 100638049 100639167 100640399
ATHAT4G34890(XDH1) AT4G34900(XDH2)
ALY9305190 9310998
CRB17877660
CSAT104716647 104721300 104729731
EUSEUTSA_v10024224mg
BRP103833679 103836769
BNA106345323 106365498 106375286 106434738 111200820
BOE106318433 106341371
RSZ108827124 108842495
THJ104817905
CPAP110811823
CIT102622737
CICCICLE_v10014051mg
PVY116140064
MINC123208797
TCC18589817
GRA105799411
GHI107889340 107891396
GAB108456712
DZI111301841
EGR104421526 104421529
GMX100800309 100816689
GSJ114375926 114388605
PVUPHAVU_005G148000g
VRA106759191
VAR108333356
VUN114185523
CCAJ109805880 109806687
APRC113854968
MTRMTR_2g098030
CAM101495267
LJALj3g3v1694660.1(Lj3g3v1694660.1)
ADU107461425
AIP107610263 107624665
AHF112706649 112771662
LANG109351322
FVE101298861
RCN112202499
PPER18780893
PMUM103326686
PAVI110760280
PDUL117624343
MDM103440363 103447973
PXB103965536
ZJU107412613
MNT21398385
CSV101211977
CMO103492036
BHJ120070770
MCHA111021441
CMAX111485375
CMOS111461442
CPEP111779652
RCU8274436
JCU105648267
HBR110633863 110639025
MESC110617223
POP7467360
PEU105126367
PALZ118035122
JRE109003655
QSU112000762 112010557 112035226
QLO115975629
TWL119996112
VVI100248547
VRI117915551
SLY101252457 101252744
SPEN107004608 107005062
SOT102596284
CANN107853580
NTA107762161 107795439
NSY104224061
NTO104111014
NAU109241093
INI109160132
ITR116003533
SIND105163571
OEU111404472
EGT105950632
SSPL121753030 121792706
HAN110866903
ECAD122602516 122602642
LSV111899848 111899849
CCAV112511831
DCR108226793
CSIN114256370
BVG104889971
SOE110801608
CQI110696014 110696015 110736203
NNU104603426
MING122070457 122070465 122071657
TSS122641860
PSOM113320865 113321339
NCOL116255762
OSA4333171
DOSAOs03t0429800-01(Os03g0429800)
OBR102707013
BDI100827961
ATS109737702 109742032
TDC119272045 119337084
TAES123049061 123125438 123143571 123181425
SBI110434890
ZMA100384368
SITA101785503
SVS117836203 117867000
PVIR120690993
PHAI112874507
PDA103715913
EGU105056188
MUS103989027
DCT110115026
PEQ110018507
AOF109822654 109834378
ATR18432832 18439972
SMOSELMODRAFT_172098(XDH-2) SELMODRAFT_443347 SELMODRAFT_444585 SELMODRAFT_83922(XDH-1)
PPP112273311 112278906
CRECHLRE_12g545101v5
VCNVOLCADRAFT_63971
CSLCOCSUDRAFT_53984
CVRCHLNCDRAFT_136969
APROF751_6411
BPGBathy11g02970
MISMICPUN_83794
GSLGasu_62880
CCPCHC_T00006216001
PPAPAS_chr2-2_0112
SLBAWJ20_3928(AOH2)
BBRXBRETT_001708
NCRNCU03350(xdh-1)
NTENEUTE1DRAFT130703(NEUTE1DRAFT_130703)
SMPSMAC_04084
PANPODANSg6463
TTTTHITE_2123410
MTMMYCTH_2311689
CTHRCTHT_0001520
MGRMGG_12738
PPEIPpBr36_06397
TMNUCRPA7_4126 UCRPA7_883
SSCKSPSK_00201
FGRFGSG_01561
FPUFPSE_00773
FVRFVEG_09642 FVEG_12680
FOXFOXG_11147 FOXG_15354
NHENECHADRAFT_74201 NECHADRAFT_93123
TRETRIREDRAFT_78797
TRRM419DRAFT_78829
MAWMAC_05768
MAJMAA_01730
CMTCCM_08980
PLJVFPFJ_07309
VALVDBG_05801
VDAVDAG_07735
CFJCFIO01_04805
CHIGCH63R_10755
SAPOSAPIO_CDS0916
ELAUCREL1_7929
PFYPFICI_08825
SSLSS1G_08428 SS1G_14350
BFUBCIN_12g02310 BCIN_14g05060
MBEMBM_00517
PSCOLY89DRAFT_706582 LY89DRAFT_781300
GLZGLAREA_08868 GLAREA_09632
ANIAN5613.2 AN9178.2
AFMAFUA_4G11220
ACTACLA_050310
NFINFIA_094210 NFIA_105140
AORAO090003001099
ANGANI_1_1056034(An03g01530) ANI_1_902184(An04g05440)
AFVAFLA_000570
ALUCAKAW2_10106S AKAW2_51514S
ACHEACHE_10608S ACHE_30019A
APUUAPUU_31650S APUU_40979S
PCSPc22g06330
PDPPDIP_33700
TMFPMAA_040820
TRGTRUGW13939_02782 TRUGW13939_07238
CIMCIMG_01495
CPWCPC735_049500
UREUREG_05104
PBLPAAG_02640 PAAG_03629
PBNPADG_01660 PADG_06197
ABEARB_02280
TVETRV_04973
AJEHCAG_01659 HCAG_06867
BGHBDBG_03499 BDBG_09398
PNOSNOG_04191 SNOG_07509
PTEPTT_04424 PTT_07497
BZECOCCADRAFT_5375 COCCADRAFT_89627
BSCCOCSADRAFT_105648 COCSADRAFT_172265
BORCOCMIDRAFT_6414 COCMIDRAFT_82012
AALTCC77DRAFT_1065456 CC77DRAFT_946656
ZTRMYCGRDRAFT_53902
PFJMYCFIDRAFT_45300 MYCFIDRAFT_48128
FFUCLAFUR5_01414
BCOMBAUCODRAFT_577650
NPAUCRNP2_5272 UCRNP2_9149
HIRHETIRDRAFT_154846
UMAUMAG_03264
PFPPFL1_06549
MBRMONBRDRAFT_16701
SREPTSG_04607
DDIDDB_G0291047(xdh)
DPPDICPUDRAFT_96745
DFADFA_00340(xdh)
ACANACA1_045720 ACA1_052830 ACA1_275400
PTIPHATRDRAFT_15968
FCYFRACYDRAFT_209625(XDH)
TPSTHAPSDRAFT_270071
AAFAURANDRAFT_36810 AURANDRAFT_71657
PIFPITG_02284
PSOJPHYSODRAFT_295142
SPARSPRG_01095 SPRG_14003
EHXEMIHUDRAFT_109218 EMIHUDRAFT_226032 EMIHUDRAFT_461094 EMIHUDRAFT_469173 EMIHUDRAFT_50708
GTTGUITHDRAFT_164776
NGRNAEGRDRAFT_62716
TVATVAG_416300 TVAG_433470
 » show all
Reference
1
  Authors
Avis, P.G., Bergel, F. and Bray, R.C.
  Title
Cellular constituents. The chemistry of xanthine oxidase. Part I. The preparation of a crystalline xanthine oxidase from cow's milk.
  Journal
J Chem Soc (Lond) 1100-1105 (1955)
Reference
2  [PMID:6960894]
  Authors
Battelli MG, Lorenzoni E.
  Title
Purification and properties of a new glutathione-dependent thiol:disulphide oxidoreductase from rat liver.
  Journal
Biochem J 207:133-8 (1982)
DOI:10.1042/bj2070133
Reference
3
  Authors
Bray, R.C.
  Title
Xanthine oxidase.
  Journal
In: Boyer, P.D., Lardy, H. and Myrback, K. (Eds.), The Enzymes, 2nd ed., vol. 7, Academic Press, New York, 1963, p. 533-556.
Reference
4  [PMID:4342395]
  Authors
Corte ED, Stirpe F.
  Title
The regulation of rat liver xanthine oxidase. Involvement of thiol groups in the conversion of the enzyme activity from dehydrogenase (type D) into oxidase (type O) and purification of the enzyme.
  Journal
Biochem J 126:739-45 (1972)
DOI:10.1042/bj1260739
Reference
5  [PMID:3459393]
  Authors
Ikegami T, Nishino T
  Title
The presence of desulfo xanthine dehydrogenase in purified and crude enzyme preparations from rat liver.
  Journal
Arch Biochem Biophys 247:254-60 (1986)
DOI:10.1016/0003-9861(86)90582-5
Reference
6  [PMID:3294898]
  Authors
Engerson TD, McKelvey TG, Rhyne DB, Boggio EB, Snyder SJ, Jones HP
  Title
Conversion of xanthine dehydrogenase to oxidase in ischemic rat tissues.
  Journal
J Clin Invest 79:1564-70 (1987)
DOI:10.1172/JCI112990
Reference
7  [PMID:2610112]
  Authors
Saito T, Nishino T, Tsushima K
  Title
Interconversion between NAD-dependent and O2-dependent types of rat liver xanthine dehydrogenase and difference in kinetic and redox properties between them.
  Journal
Adv Exp Med Biol 253B:179-83 (1989)
DOI:10.1007/978-1-4684-5676-9_27
Reference
8  [PMID:2350174]
  Authors
Carpani G, Racchi M, Ghezzi P, Terao M, Garattini E.
  Title
Purification and characterization of mouse liver xanthine oxidase.
  Journal
Arch Biochem Biophys 279:237-41 (1990)
DOI:10.1016/0003-9861(90)90487-J
Reference
9  [PMID:11092937]
  Authors
Eger BT, Okamoto K, Enroth C, Sato M, Nishino T, Pai EF, Nishino T.
  Title
Purification, crystallization and preliminary X-ray diffraction studies of xanthine dehydrogenase and xanthine oxidase isolated from bovine milk.
  Journal
Acta Crystallogr D Biol Crystallogr 56 Pt 12:1656-8 (2000)
DOI:10.1107/S0907444900012890
Reference
10 [PMID:18513323]
  Authors
Nishino T, Okamoto K, Eger BT, Pai EF, Nishino T
  Title
Mammalian xanthine oxidoreductase - mechanism of transition from xanthine dehydrogenase to xanthine oxidase.
  Journal
FEBS J 275:3278-89 (2008)
DOI:10.1111/j.1742-4658.2008.06489.x
Other DBs
ExplorEnz - The Enzyme Database: 1.17.3.2
IUBMB Enzyme Nomenclature: 1.17.3.2
ExPASy - ENZYME nomenclature database: 1.17.3.2
UM-BBD (Biocatalysis/Biodegradation Database): 1.17.3.2
BRENDA, the Enzyme Database: 1.17.3.2
CAS: 9002-17-9
LinkDB

DBGET integrated database retrieval system