Canis lupus familiaris (dog): 483378 Help Entry 483378            CDS       T01007                                  Symbol FASN Name (RefSeq) fatty acid synthase   KO K00665   fatty acid synthase, animal type [EC:2.3.1.85] Organism cfa  Canis lupus familiaris (dog) Pathway cfa00061   Fatty acid biosynthesis cfa01100   Metabolic pathways cfa01212   Fatty acid metabolism cfa04152   AMPK signaling pathway cfa04910   Insulin signaling pathway cfa04936   Alcoholic liver disease Module cfa_M00082   Fatty acid biosynthesis, initiation cfa_M00083   Fatty acid biosynthesis, elongation Brite KEGG Orthology (KO) [BR:cfa00001]  09100 Metabolism   09103 Lipid metabolism    00061 Fatty acid biosynthesis     483378 (FASN)  09130 Environmental Information Processing   09132 Signal transduction    04152 AMPK signaling pathway     483378 (FASN)  09160 Human Diseases   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     483378 (FASN)  09180 Brite Hierarchies   09181 Protein families: metabolism    01004 Lipid biosynthesis proteins [BR:cfa01004]     483378 (FASN)   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:cfa04147]     483378 (FASN) Enzymes [BR:cfa01000]  2. Transferases   2.3  Acyltransferases    2.3.1  Transferring groups other than aminoacyl groups     2.3.1.85  fatty-acid synthase system      483378 (FASN) Lipid biosynthesis proteins [BR:cfa01004]  Fatty acid synthase   Animal type    483378 (FASN) Exosome [BR:cfa04147]  Exosomal proteins   Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)    483378 (FASN)   Exosomal proteins of breast milk    483378 (FASN)   Exosomal proteins of colorectal cancer cells    483378 (FASN)   Exosomal proteins of bladder cancer cells    483378 (FASN) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Acyl_transf_1 ketoacyl-synt Thioesterase KR KAsynt_C_assoc Ketoacyl-synt_C FAS_pseudo-KR ADH_zinc_N_2 ADH_zinc_N PKS_DH_N PP-binding Methyltransf_12 adh_short PS-DH Methyltransf_11 Thiolase_N DUF7080 Methyltransf_31 Methyltransf_25 Methyltransf_23 AlaDh_PNT_C ACP_syn_III Motif Other DBs NCBI-GeneID:  483378 NCBI-ProteinID:  XP_038478874 Ensembl:  ENSCAFG00000006006 VGNC:  40736 LinkDB All DBs Position 9:835096..852365 Genome browser AA seq 2530 aa AA seqDB search MEEVVIAGMSGKLPESDNMEEFWANLIGSVDMVTDDDRRWKAGLYGLPRRSGKLKDLSRF DASFFGVHPKQAHTMDPQLRLLLEVAYEAILDGGINPASLRGTRTGVWVGVSGSEASEAL SRDPETLLGYSMVGCQRAMMANRLSFFFDFKGPSVALDTACSSSLMALHSAYQAIRSGEC PCAIVGGINILLKPNTSVQFMKLGMLSPEGICKSFDEAGAGYCRAEAVVAMLLTKKSLAR RVYATILNAGTNTDGFKEQGVTFPSGEVQEQLIRSLYEPAGLAPESLEYIEAHGTGTKVG DPQELNSIDRALCSTRREPLLIGSTKSNMGHPEPASGLAALAKVLLSLEHGLWAPNLHFH SPNPEILALQDGRLQVVDRPRPVRGGNVGINSFGFGGSNVHVVLQPNTRPPRPTTPHITL PRLLRASGRTPEAVRCLLEKGQQHSRDVAFVTMLNDIAASSPSAMPFRGYTVLGSEDGSH EVQEVQQLPAGRRPLWFICSGMGAQWRCMGSSLLRLSSFHNSILRSSEALKPLGLQLPEL LLSTDETTFDDIVHAFVSLTAIQIALIDLLTSMGLRPDGIIGHSLGEVACGYADGCLSQE EAVLTAYWRGQCIKEASIPPGAMAAVGLTWEECKRRCPPGVVPACHNSEDTVTISGPQAE VAAFLEELRQEGVFAKEVRTGGMAFHSYFMESIAPTLLKALKKVIREPKPRSARWLSTSI PEAQWQGSLARMCSAEYSVNNLVSPVLFQEALCHVPEHAVVVEIAPHALLQAVLKRGLKP SCAIIPLMKKEQKDNLEFFLRNTGKLHLLGMDANPNGLFPPMDFPVPRGTPLISPHIKWD HSQIWDVPAAEDFPNGSTGSSAATICKIDTSPESPDHYLVDHCIDGRVLFPATGYLCLAW KMLARALNQNMEEMPVVFEDVTLHQATILPKTGTMALEVRLLEASQSFEVSENGNLIVSG KVYQWEDPDPKLFDLHGGADPVDPTDPTDPMAAFRLTQGDVYKELRLRGYDYGPHFQGIL ETNLEGKAGQLLWKDNWVVFLDAMLQTSILGNPQRTLCLPTRITSIHIDPALHQQKVYSL KGDARVVDVKVSSCLNSTVAGGALILGLHASVAPRRQQEQHAPILEKFSFTPYMEGGVLA GNAALQEELQLCRGLAQALQTKVAQQGLKMVVPGLDGAQVPREFPQGGLPQLLAAACQLQ LNGNLQLELAQLLAQQRSLLHDDPLLCGLLDSSALKACTDTALENMTSLRMHIVEVLAGD GRLYTRIPTLLSTQPLLQLDYTATDRHPQALEAAQTKLQELGMAQGQWDPTQPAPSNLGT ADLLVCNCAVATLPDPASALSHMVAAVREGGFLLLHALLRGHPLGETVAFLTGPEQQQQQ QQLGGSQSLLSQDEWERVFAGASLHLVALKRSFYGSALFLCRRPGPQDSPVFLPVEDTSF RWVDSLKNVLADSSSRPVWLTATNCITSGVVGMVNCLRKEPSGHRVRCILVSNLSSTSPI PKMDPSSSELQKVLQGDLVMNIYRDGSWGAFRHFPLEHGLPEEQTEHAFVNVLTRGDLSS IRWVCSPLRHAQLTEPGVQLCTVYYASLNFRDIMLATGKLSPDAIPGKWAARDCMLGMEF SGRDASGKRVMGLVPAEGLATSVLLSPDFLWDVPSSWTLEEAATVPVVYTTAYYSLVVRG RVQRGETVLIHSGSGGVGQAAIAIALSLGCRVFTTVGSAEKKAYLQARFPQLSDTSFANS RDTSFEQHVLRHTAGKGVDLVLNSLAEEKLQASVRCLAQHGRFLEIGKFDLSNNHLLGMA VFLKNVTFHGILLDALFDEAGHGWREVAALLQAGIRDGVVRPLKRTVFPKNQVEDAFRFM AQGKHIGKVVVQVLEEEQEAALQVTRPTMMTAVSKTFCPAHKSYVITGGLGGFGLQLAQW LVLRGAQKLVLTSRSGIRTGYQAKLIREWRRQGVQVLVSTSNIGSLDGAQSLIAEAAQLG PVGGVFNLAVVLRDAMLENQTPEFFQDVNKPKYSGTVNLDRVTRAACPELDYFVAFSSVS CGRGNAGQTNYGFANSTMERVCEKRRHDGLPGLAVQWGAIGDVGIILEMMGSNDTIVGGT LPQRMTSCLEVLDLFLNQPHPVLSSFVLAEKKAAAQGDGSTQHDLMKAVAHILGIRDLAT VNLDSTLADLGLDSLMGVEVRQMLEREHDLVLSMRDIRQLTLRKLQELSSKAGMADERGV PTPKQDSPTYQQAQLNLSTLLVNPEGPTLTRLNSVQSSERPLFLVHPIEGSITVFHSLAA KLSIPTYGLQCTRAAPLDSIQSLAAYYIECIRQVQPEGPYRIAGYSYGACVAFEMCSQLQ AAQQSPAPTHNSLFLFDGSHSYVLAYTQSYRAKMTPGCEAEAEAEAMCFFVQQFTDMEHD KVLEALLPLGSLEERVVASVDLIQHSHAGLDPRELSFAARSFYHKLRAAEQYTPQATYHG NVTLLRAKTGSMYGEGLGADYNLSQVCDGKVSVHVIEGDHRTLLEGSGLESILSIIHSSL AEPRVSVREG NT seq 7593 nt NT seq  +upstreamnt  +downstreamnt atggaggaggtggtgattgctggcatgtccgggaagttgcccgagtcggacaacatggag gagttctgggccaatctcatcggctctgtggacatggtgacagacgacgacaggaggtgg aaggcagggctttacggcctgcccaggaggtccggcaaactgaaggacctgtcccggttc gacgcctccttcttcggggtccaccccaagcaggcccacacgatggacccgcagctgcgc ctgctgctagaggtcgcgtacgaggccatcttggacggaggcatcaacccagcgtcactc cgagggacacgcaccggtgtctgggtgggcgtgagtggctctgaggcctcagaggccctc agccgagaccccgagaccctcttgggctacagcatggtgggctgccagcgcgccatgatg gccaaccgcctctccttcttctttgattttaaagggcccagcgtcgctctagacacggcc tgctcctccagcctgatggctctgcacagcgcctaccaggccatccgcagcggggagtgc ccgtgtgccatcgtgggtggcattaacatcctgctcaagcccaacacttctgtacagttc atgaagctgggtatgctgagtccagagggcatctgcaagtccttcgatgaggctggagcc ggctactgccgggcggaggccgtggtggccatgctgctgaccaagaagtccctggcccgg cgagtgtacgctaccatcctgaatgccggcaccaacacggatggcttcaaggaacaaggt gtgaccttcccgtccggggaggtacaagagcagctcatccgctccctgtacgagccggcg gggctggccccggagtccctcgagtacatcgaagcccacggcacaggcaccaaggtgggc gacccccaggagctgaacagcatcgaccgagccctttgcagcacccgccgggagcccctg ctgatcgggtccacaaagtccaacatggggcacccagagcccgcctcggggctcgcggct ctggccaaggtgctgctgtctctggaacacgggctctgggctcccaacctgcacttccac agcccgaaccctgagatcctggcactccaggatgggcggctacaggtggtggaccggccc cggccggtccgcggaggcaacgtgggcatcaactccttcggctttggcggctccaatgtg cacgtcgtcctccagcccaacacgcggccacccaggccgaccaccccacacatcactttg ccccgtctgctgcgggccagcgggcggaccccagaggccgtgcggtgcctgctggaaaag ggccagcagcacagccgggacgtggccttcgtgaccatgctcaatgacatcgcggccagc tccccctccgccatgcccttccggggctacactgtgctgggcagcgaggacggcagccac gaggtgcaggaggtgcagcagctgcctgccggccggcgtcccctctggttcatctgctct gggatgggtgcacagtggcgctgcatggggtcgagcctcttgcgcctgagcagcttccac aattccatcctgcgctccagtgaggccctgaagcccctgggcctacagctgcctgagctg ctgctgagcacagacgagaccacttttgacgacatcgtccatgccttcgtgagcctcacc gccatccagattgccctcatagacctgctgacctccatgggcctgcgacccgacggcatc atcgggcactccctgggggaggtggcctgcggctacgcagatggctgcctttctcaggag gaggccgtcctcactgcctactggaggggccagtgcatcaaggaggccagcatcccacca ggggccatggcagccgtgggcctaacctgggaggagtgtaaacggcgctgtccccctggc gttgtgcccgcctgccacaactccgaagacacagtgaccatctcgggacctcaggctgag gtggccgcgtttctggaggagctgaggcaggagggcgtgtttgccaaggaggtgcgcacg ggcggcatggccttccactcctacttcatggagtccatcgcccccacgctgctgaaggcc ctcaagaaggtgatccgggagccaaagccccgctccgcacgctggctcagcacatccatc cccgaggcccagtggcagggcagcctggcccgcatgtgctcggcggagtacagtgtcaac aacctggtgagccccgtgctgttccaggaggcgctgtgccacgtgcctgagcacgccgtg gtggtggagatcgcacctcacgccctgctgcaggccgtcctgaagagaggcctcaagccc agctgcgccatcatccccctgatgaagaaggagcagaaggacaacctggagttcttcctc aggaacacgggcaagctgcatctgctgggcatggacgccaaccccaacggcctgttccca cccatggacttcccggttccccgggggacccctctcatctccccccacatcaagtgggac cacagtcagatctgggacgtgcctgccgccgaggacttccccaacggctccaccggctcg tccgctgccaccatctgcaagattgacaccagccccgagtcccctgaccactacctggtg gaccactgcatcgatggccgtgtcctcttccctgccaccggctacctgtgcctggcctgg aagatgctggcacgtgccttgaaccaaaacatggaggagatgcccgtggtgtttgaggac gtgacgctgcaccaggccaccatcttgcccaagaccgggaccatggccctagaagtgcgg cttctagaggcttcccagagctttgaggtgtctgagaatggcaacctgatagtgagcgga aaggtgtaccagtgggaggaccctgaccccaagctgttcgacctccatggtggcgcagac cccgtggaccccacggaccccacggaccccatggccgcgttccgcctcacccagggggac gtgtacaaggagctgcggctgcgtggctatgactacggcccccactttcagggcatcctg gagaccaaccttgaaggcaaagccggccagctgctgtggaaggacaactgggtggtcttc ctggacgccatgctgcagacgtccatcctgggcaatccacagcgcaccctgtgcctgccc acccgcatcacctccatccacatcgaccccgcccttcaccagcagaaagtgtactcgctg aagggcgatgcccgagtggtcgacgtgaaggtgagcagctgcctgaacagcacggtagcc ggcggtgccctcatcttgggcctgcacgcttctgtggccccaagacggcagcaggagcag catgcacccatcctagagaagttctccttcaccccctacatggagggaggcgtcctggct ggaaacgcagccctgcaggaggagctgcagctgtgtagggggctggcacaagcactgcag accaaggtggcccagcagggcctgaagatggtggtacccgggctggatggggcccaggtc ccccgcgagttcccacagggaggcctgcctcagttgctggccgctgcctgccagctgcag ctcaatggcaacctgcagctggagctggcccagctcctggcccagcagaggtccctgctg cacgatgatcccctgctctgcggtcttctggactcctcggcgttgaaggcgtgcacggac accgccctggagaatatgaccagtctcaggatgcacatagtggaggtgctggctggtgat ggtcgcctgtacacccgcatccccacgctgctcagcacccagcccttgctgcagctggac tacacagccaccgaccgccaccctcaggccctggaggccgcccagaccaaactgcaggag ctcgggatggcccagggccagtgggaccccacccagcccgcccccagcaacctgggcacg gccgacctgctggtgtgcaactgtgcggtggccaccctccccgacccagcctcggccctc agccacatggtggccgctgtcagggagggcggcttcttgctgctgcacgccctgctcagg ggacaccccctgggagagaccgtcgccttcctcacgggccctgagcagcagcagcagcag cagcagctggggggcagccagagcctcctgagccaggacgagtgggaacgagtgtttgcg ggcgcgtcgctgcacctggtggccctgaagaggtccttctacggttccgcgctcttcctg tgccgccggccaggcccccaggacagccccgtcttcctgcctgtggaggacaccagcttc cgatgggtggactcactgaagaacgttctggctgacagctcctcccgacccgtgtggctg acagccactaactgcatcacgtcgggcgtcgtgggcatggtgaactgtctccgcaaagag cccagtgggcaccgggttcgatgcatcctggtgtccaacctgagcagcacatcccccatc cccaagatggaccccagctcctcagagttgcagaaggtgttacagggggacctcgtgatg aacatctaccgggatgggtcctggggagccttccgccatttcccactggagcacggccta ccagaggagcagactgagcacgccttcgtgaatgtcctcacccggggggacctctcctcc atccgctgggtctgctctcctctgcgtcatgcccagctcactgagcctggggtccagctc tgcaccgtctactacgcctcccttaacttccgagacatcatgttggccacgggcaagctc tcccctgatgccatcccaggaaagtgggccgcgcgggactgcatgctgggcatggagttc tccggccgagacgccagtggcaagcgtgtgatgggactggtgcccgctgaaggcctggcc acctccgttctgctgtctccggacttcctgtgggacgtgccatccagctggaccctagag gaggcagcgaccgtgcccgtggtgtacaccaccgcctactactcgctggtggtgcggggg cgcgtgcagcgtggggagacggtgctcatccactcgggctcgggcggcgtgggccaggcc gccatcgccatcgccctgagcctgggctgccgcgtcttcaccaccgtgggctcggccgag aagaaggcatacctccaggccaggttcccccagctcagtgacaccagctttgccaactcc cgggacacgtcctttgaacagcacgtgctgcggcacacggccgggaagggtgtcgacctg gttctgaactctctggccgaagagaagctgcaggccagtgtgcggtgcctggcccagcac ggccgcttcctggaaatcggcaaattcgacctttccaacaaccacttactgggcatggcc gtcttcctgaagaacgtgaccttccacgggattctgctggacgcgctctttgacgaagca ggccacggctggcgggaggtggccgcgctgctgcaggcgggcatccgggatggtgtagtg cggcccctcaagcgcaccgtgttccccaagaaccaggtggaggacgccttccgcttcatg gcccaagggaagcacatcggcaaagtggtcgtgcaggtgctcgaagaggagcaggaggcg gcgctacaggtgaccaggcccaccatgatgacagccgtgtccaagaccttctgcccggcc cataagagctacgtcatcaccgggggcctgggcggtttcggcctgcagctggcccagtgg ctcgtgttgcgaggagcccagaaactcgtgctgacctcccgctctggaatccgcacaggc taccaggccaagctcatccgtgagtggaggcgccagggcgtgcaggtccttgtgtccacc agcaacatcggctcgctagatggagcccagagcctcatcgctgaggccgcacagctgggg cctgtgggaggagtcttcaacctggccgtggtcctgagagatgccatgctggagaaccaa actcctgagttcttccaggacgtcaacaagcccaagtacagtgggaccgtgaacttggac agggtgacacgggcggcatgccccgagctggactactttgtggccttctcgtctgtgagc tgcgggcgcggcaacgctggccagaccaactacggcttcgccaactccaccatggagcgc gtgtgtgagaagcgccggcatgatggcctcccaggcctcgccgtgcagtggggcgccatc ggtgacgtgggcatcatcctggagatgatgggttccaacgacacgatcgtcggtgggacg ctgcctcagcggatgacctcctgcttggaggtgctggacctcttcctgaaccagcctcac cccgtcctgagcagcttcgtgctggctgagaagaaggccgccgcccagggtgatggcagc acccagcacgacctcatgaaggctgtggcccacatcctgggcatccgggacctggccacc gtcaacctggacagcacactggcggacctgggcctggactcgctcatgggcgtggaggtg cgccagatgctggagcgcgagcacgacctggtgctgtccatgcgggacatccgccagctc acgctccggaagctgcaggagctttcgtcgaaggctggcatggctgacgagcggggggtg cccacacccaagcaggacagccccacctatcagcaggcgcagctgaacctcagcaccctg ctggtgaacccggagggccccaccctgacgcgactgaactccgtgcagagctcagagcgg cctctgttcctggtgcaccccatcgaaggctccatcaccgtgttccacagcctggccgcc aagctcagcatccccacctatggcttgcaatgcacccgagctgcacccctggacagcatc cagagtctggctgcctactacatcgagtgcatccggcaggtgcagcccgaggggccctac cgcattgccggctactcctacggggcctgtgtggccttcgagatgtgctcgcaactgcag gcggcacagcagagtccagcccccacacacaacagcctcttcctgtttgatggctcacac agctatgtgctggcctacacgcagagctaccgagccaagatgacccccggctgcgaggcg gaggccgaggcggaggccatgtgcttctttgtgcagcagttcaccgacatggagcacgac aaggtgctggaggcactgctgccccttgggagcctggaggagcgcgtggtggcctccgtg gacctgatccagcacagccacgcgggcctggacccccgcgagctgagcttcgccgcgcgc tccttctaccacaagctgcgcgccgccgagcagtacacgccgcaggccacctaccacggc aatgtgacgctgctgcgcgccaagacgggcagcatgtacggcgagggcctgggcgccgac tacaacctgtcccaggtgtgcgatggcaaggtgtccgtgcacgtgatcgagggtgaccac cgcacgctgctggagggcagcggcctagagtccatcctcagcatcatccacagctccctg gccgagccgcgcgtcagcgtgcgggagggctag

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