Canis lupus familiaris (dog): 484401 Help Entry 484401            CDS       T01007                                  Symbol SPHK2 Name (RefSeq) sphingosine kinase 2 isoform X1   KO K04718   sphingosine kinase [EC:2.7.1.91] Organism cfa  Canis lupus familiaris (dog) Pathway cfa00600   Sphingolipid metabolism cfa01100   Metabolic pathways cfa04020   Calcium signaling pathway cfa04071   Sphingolipid signaling pathway cfa04072   Phospholipase D signaling pathway cfa04148   Efferocytosis cfa04370   VEGF signaling pathway cfa04371   Apelin signaling pathway cfa04666   Fc gamma R-mediated phagocytosis cfa05152   Tuberculosis Module cfa_M00100   Sphingosine degradation Brite KEGG Orthology (KO) [BR:cfa00001]  09100 Metabolism   09103 Lipid metabolism    00600 Sphingolipid metabolism     484401 (SPHK2)  09130 Environmental Information Processing   09132 Signal transduction    04370 VEGF signaling pathway     484401 (SPHK2)    04371 Apelin signaling pathway     484401 (SPHK2)    04020 Calcium signaling pathway     484401 (SPHK2)    04072 Phospholipase D signaling pathway     484401 (SPHK2)    04071 Sphingolipid signaling pathway     484401 (SPHK2)  09140 Cellular Processes   09141 Transport and catabolism    04148 Efferocytosis     484401 (SPHK2)  09150 Organismal Systems   09151 Immune system    04666 Fc gamma R-mediated phagocytosis     484401 (SPHK2)  09160 Human Diseases   09171 Infectious disease: bacterial    05152 Tuberculosis     484401 (SPHK2) Enzymes [BR:cfa01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.91  sphingosine kinase      484401 (SPHK2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  DAGK_cat YegS_C Motif Other DBs NCBI-GeneID:  484401 NCBI-ProteinID:  XP_005616401 Ensembl:  ENSCAFG00000003961 VGNC:  46737 UniProt:  A0A8P0S9M6 A0A8I3MH69 LinkDB All DBs Position 1:complement(107202917..107211393) Genome browser AA seq 674 aa AA seqDB search MASGEGTSGPAPIPSLESRRPDAQRPDQELTWSWGHRPRSALDRAEAMAPPPPPPLAAST PLLHGEFGSYPARGSRFALTLTPQALHIQRLRPKPEARPRGGLVLLAEVSGCCTLRSRSL SDSAAYFCIYTYPQGRRGGRLGGRRRAPRTFRADGAATYEENRAEAQRWATALMCLLRGV PLPGDGEITPELLPRPPRLFLLVNPFGGRGLAWQWCKNHVLPMISEAGLSFNLIQTERQN HARELVQGLNLSEWDGIVTVSGDGLLFEVLNGLLGRPDWEEAVKTPVGILPCGSGNALAG AVNQHGGFEPALGVDLLLNCSLLLCRGGSRPLDLLSVTLASGSRCFSFLSVAWGFVSDVD IQSERFRALGSARFTLGTVLGLANLHTYRGRLSYLPAAVEPASPTPAHGLPRAKSELTLA PAPAPAPPVAHSPLHRSVSDLPLPLPMPQPALTSPGSPEPLPILSLNGGGPELAGDWGGA GDAPLSPDPLLPSPPSSPKAALLSPITEGVPEMPASSGLPPPTPDAPEAISTGGPPDHLL PPLGTPLPPGWVTLEGDFVLMLAISPSHLGADLVAAPHARFDDGLVHLCWVRGGISRAAL LRLFLAMERGSHFNLGCPQLGYAAARAFRLEPLTPRGVLTVDGEQVEYGPLQAQMHPGLG TLLTGPPGCPGREP NT seq 2025 nt NT seq  +upstreamnt  +downstreamnt atggcctctggggaggggacctcaggcccggctcccatcccctccctggagagcaggcgg ccagacgcccagaggccagaccaggagctgacctggagctggggccacaggcctagaagc gccctggacagggccgaggccatggcccccccaccgccgccaccattggccgccagcacc ccgctcctgcatggcgagtttggctcctacccagcccgcggctcccgcttcgccctcact ctcacaccacaggccctgcacatacagcggctgcgtccgaagcctgaagcccggccccgg ggcggcttggtcctgttggccgaggtgtctggttgctgcacccttcggagccgcagcctc tcagactcagcagcctacttctgcatctacacctacccgcagggccggcgcgggggccgg cttgggggccggcgcagagcccctcgcacctttcgggccgacggggcagccacctacgag gagaaccgcgctgaggcccagcgctgggccactgccctcatgtgtctgctccgtggagtg ccactgcctggggatggggaaataacccctgagcttctgccaaggccaccccgattgttt ctactggtcaatcccttcggggggcggggtctggcctggcagtggtgtaagaaccacgtg ctgcccatgatctctgaagccgggctgtccttcaacctcatccagacagaacggcagaac cacgcccgggagctggttcagggactgaacctgagtgagtgggacggcatcgtgacagtc tcaggagacgggctgctgtttgaggtgctgaacgggctcctaggccgccctgattgggaa gaagctgtgaagacacctgtgggcattctcccctgtggctcaggcaatgccctggctgga gctgtgaaccagcatggggggtttgaacctgccctgggtgtcgacctgctgctcaactgc tcactgctcctctgccggggtggcagccgcccgctggatctgctctctgtgacactggcc tcgggttcccgctgtttctccttcctgtccgtggcctggggcttcgtgtcagatgtggac atccagagcgagcgcttcagggccctgggcagtgcccgcttcacactgggcacggtgctg ggccttgccaacctgcacacataccgcggacgcctctcctacctccctgccgctgtggaa cctgcctcacccacccctgctcacggcctgccccgtgccaagtcagagctgactctggcc ccagccccggccccagccccacccgtggcacactcacccctgcatcgctcggtatctgac ctgcccctgccactgcccatgccccagcctgccctgacctcccctggctcacctgagccc ctgcccatcctgtctctcaacggtgggggcccagagttggctggggactggggtggggct ggggatgccccactgtccccagacccactgctgccctcaccacctagttcccctaaggca gctttattgtcccccatcaccgagggggttccagaaatgccagcctcctctgggctccca cctcccacccctgatgccccggaagcgatctctactgggggcccacctgaccacctgctc cctcctctgggcacccccctccccccaggctgggtgacgctggagggggactttgtgctt atgttggccatctcacccagccacctgggggctgatctggtggcagctccccacgcgcgc tttgacgacggcctggtgcacctgtgctgggtgcggggcggcatctcgcgagctgcgctg ctgcgcctttttctggccatggagcgagggagccacttcaacctgggctgtccgcagctg ggctatgccgcggcccgtgccttccgcctcgagcctctcacgcctcggggcgtgctcact gtggacggagagcaggtggagtatgggccactgcaggcgcagatgcatccaggcctgggt acactgctcaccgggcctccgggctgcccaggtcgggagccttga

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