Canis lupus familiaris (dog): 484990 Help Entry 484990            CDS       T01007                                  Symbol INSR Name (RefSeq) insulin receptor isoform X3   KO K04527   insulin receptor [EC:2.7.10.1] Organism cfa  Canis lupus familiaris (dog) Pathway cfa04010   MAPK signaling pathway cfa04014   Ras signaling pathway cfa04015   Rap1 signaling pathway cfa04022   cGMP-PKG signaling pathway cfa04066   HIF-1 signaling pathway cfa04068   FoxO signaling pathway cfa04072   Phospholipase D signaling pathway cfa04081   Hormone signaling cfa04150   mTOR signaling pathway cfa04151   PI3K-Akt signaling pathway cfa04152   AMPK signaling pathway cfa04211   Longevity regulating pathway cfa04213   Longevity regulating pathway - multiple species cfa04520   Adherens junction cfa04910   Insulin signaling pathway cfa04913   Ovarian steroidogenesis cfa04923   Regulation of lipolysis in adipocytes cfa04930   Type II diabetes mellitus cfa04931   Insulin resistance cfa04932   Non-alcoholic fatty liver disease cfa04960   Aldosterone-regulated sodium reabsorption cfa05010   Alzheimer disease cfa05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:cfa00001]  09130 Environmental Information Processing   09132 Signal transduction    04014 Ras signaling pathway     484990 (INSR)    04015 Rap1 signaling pathway     484990 (INSR)    04066 HIF-1 signaling pathway     484990 (INSR)    04068 FoxO signaling pathway     484990 (INSR)    04072 Phospholipase D signaling pathway     484990 (INSR)    04022 cGMP-PKG signaling pathway     484990 (INSR)    04151 PI3K-Akt signaling pathway     484990 (INSR)    04152 AMPK signaling pathway     484990 (INSR)    04150 mTOR signaling pathway     484990 (INSR)   09133 Signaling molecules and interaction    04081 Hormone signaling     484990 (INSR)  09150 Organismal Systems   09152 Endocrine system    04923 Regulation of lipolysis in adipocytes     484990 (INSR)    04913 Ovarian steroidogenesis     484990 (INSR)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     484990 (INSR)   09149 Aging    04211 Longevity regulating pathway     484990 (INSR)    04213 Longevity regulating pathway - multiple species     484990 (INSR)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     484990 (INSR)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     484990 (INSR)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     484990 (INSR)    04932 Non-alcoholic fatty liver disease     484990 (INSR)    04931 Insulin resistance     484990 (INSR)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:cfa01001]     484990 (INSR)   09183 Protein families: signaling and cellular processes    04090 CD molecules [BR:cfa04090]     484990 (INSR) Enzymes [BR:cfa01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.1  receptor protein-tyrosine kinase      484990 (INSR) Protein kinases [BR:cfa01001]  Receptor tyrosine kinases (RTK)   INSR family [OT]    484990 (INSR) CD molecules [BR:cfa04090]  Proteins   484990 (INSR) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase Recep_L_domain Furin-like Insulin_TMD fn3 Ig_DSCAM-DSCAML_C Kinase-like B2 DUF4476 Motif Other DBs NCBI-GeneID:  484990 NCBI-ProteinID:  XP_022262798 Ensembl:  ENSCAFG00000018170 VGNC:  42043 LinkDB All DBs Position 20:complement(51822227..51957301) Genome browser AA seq 1186 aa AA seqDB search MRCFPGGAKGTPNKVEPCPRGDFCPTICKSHGCTAEGLCCHSECLGNCSEPDDPTKCVAC RNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHNKCKNSRRQGCHQYVIHNNKCIPEC PSGYTMNSSNLMCTPCLGPCPKVCHILEGEKTIDSVTSAQELRGCTVVNGSLIINIRGGN NLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETLEIGNYSFYALDNQNL RQLWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQERNDIALKTNGDQASC ENELLKFSYIRTSYDKILLKWEPYWPPDFRDLLGFMLFYKEAPYQNVTEFDGQDACGSNS WTVVDIDPPLRSNDPKSQNHPGWLMRGLKPWTQYAIFVKTLVTFSDERRTYGAKSDIIYV QTDATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVFWERQAEDSELYELDYCL KGLKLPSRTWSPPFEAEGSQKHNQSEYEESAGECCSCPKTDSQILKELEESSFRKTFEDY LHNVVFVPRKSSSSPGAEDTRPSRKRRALSDAGNVTAAIPTVPGFPNTSTSTPTSPEEHK PFEKVVNKESLVISGLRHFTGYRIELQACNQDSPEERCSVAAYVSARTMPEAKADDIVGP VTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHLCVSRRHFALERGCRLRGL PPGNYSVRVRATSLAGNGSWTEATYFYVTDYLDVPSNIAKIIIGPLIFVFLFSVVIGSIY LFLRKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVPDEWEVPREKITLLRELGQGSFGM VYEGNARDIVKGEPETRVAVKTVNESASLRERIEFLNEASVMKGFTCHHVVRLLGVVSKG QPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMAAEIADGMAYLNAKKFV HRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMAPESLKDGVFTTS SDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQPDNCPERVTDLMRMCWQFN PKMRPTFLEIVDLLKDDLHPSFPEVSFFHSEENKAPESEELEMEFEDMESVPLDRASHSQ REEAGGRDAGSSLGLKRSYEEHIPYTHMNGGKKNGRILTLPRSNPS NT seq 3561 nt NT seq  +upstreamnt  +downstreamnt atgaggtgttttcctgggggtgcaaaggggacacccaacaaggtggagccgtgtccccgt ggagacttttgtccgaccatctgcaagtcgcatggctgcaccgccgagggcctctgctgc cacagcgagtgtttaggcaactgctccgagcccgacgaccccaccaagtgcgtggcctgt cgcaacttctacctggatggcaggtgcgtggagacctgcccacccccgtactaccacttc caagactggcgctgcgtgaacttcagcttctgccaggacctgcacaacaaatgcaagaac tcccggagacagggctgccaccagtacgtcatccacaataacaagtgcatccccgagtgc ccctctggctacacgatgaattccagcaacctgatgtgcactccgtgcctgggcccctgt cccaaggtctgccacattctggaaggcgagaagaccatcgactcagtgacgtctgcccag gagcttcgaggctgcactgttgtcaacggaagtctaatcatcaacattcgagggggcaac aacctggcggccgagctggaggccaacctcggactcattgaagagatttccgggtacctg aaaatccggagatcctatgctcttgtgtctctttcctttttccggaagttgcggctgatt cgaggggagaccttggagatcgggaactactctttctatgccttggacaaccagaaccta aggcagctatgggactggagcaaacacaacctcaccatcactcaggggaaactcttcttc cactataatcccaaactctgcttgtctgagatccacaagatggaggaagtctcaggaacc aaggggcgccaggagaggaacgacattgccctgaagaccaacggggaccaggcgtcttgt gaaaacgaactacttaaattttcttacattcggacgtcttatgacaagatcttgctgaaa tgggagccctactggccccctgacttccgagacctcctggggttcatgctcttctacaaa gaggccccttatcagaatgtgaccgagtttgatgggcaggacgcgtgtggctccaacagc tggacggtggtggacattgacccacctctgcggtccaacgaccccaaatcgcagaaccac ccggggtggctgatgcggggtctcaagccctggacccaatatgccatctttgtcaagacc ttggtcaccttttctgatgaacgccgcacgtatggagccaagagtgacatcatctatgtg cagacagatgccactaatccttccgtccccctggatccaatctcggtttcgaattcctcg tcccagattattctgaagtggaagcctccctctgaccccaatggcaatatcacgcactac ctggttttctgggagaggcaggccgaagacagtgagctctatgagttggattattgcctc aaagggttgaagctgccctcccggacctggtctccgccgttcgaggccgagggctcccag aagcacaaccagagtgaatacgaggagtctgccggcgaatgctgctcctgccccaaaacg gactctcagatcctcaaggagctagaggagtcctcttttaggaagacgtttgaggattac ctgcacaacgtggtgtttgtccccagaaaatcctcttcgagccctggtgctgaggacact aggccatcgaggaaacgcagggcgctcagtgatgctggcaacgtgacagcagctataccc acagttcccggtttccccaacacctcgaccagcacgcccacgagcccggaggagcacaag cccttcgagaaagtggtgaacaaagaatctctggtcatctccggtctgcgccacttcact ggctaccgcatcgagctgcaggcttgcaaccaagactcccccgaggagaggtgcagcgtg gcggcctatgtcagcgccaggaccatgcccgaagccaaggcagacgacatcgttggcccc gtgacccacgaaatcttcgagaacaatgtcgttcacttgatgtggcaggagccaaaggaa cccaatggtctgatcgtgctttatgaagtgagttaccgacggtatggcgatgaggagctt cacctgtgtgtctcccggaggcattttgctctggagcgtggctgcaggctacgcgggctg cctccggggaattacagcgtgcgagtccgggccacctccctggcgggtaatggctcctgg acagaagccacctatttctacgtgacagactatttagatgtcccatcgaatattgcaaaa attatcatcggccccctcatctttgtctttctcttcagtgttgtgattggaagtatttac ctgttcctgagaaagaggcagccggatgggccactgggaccgctgtatgcttcttcaaac cctgagtacctcagtgccagtgatgtgtttccatgttctgtgtatgtgccggacgagtgg gaggtgccgcgggagaagatcaccctcctgcgcgagctggggcaaggctccttcggcatg gtgtacgagggcaacgccagggacatcgtcaagggtgagcccgagacccgcgtggccgtc aagaccgtcaacgagtccgccagcctgcgagagaggatcgagtttctcaatgaggcatca gtcatgaagggcttcacctgtcaccacgtggtccgcctcctgggggtggtgtccaaaggc caaccgacgctggtggtgatggagctgatggctcatggagacctgaagagctacctccgc tccctgcggccggaggctgagaataaccccggccgccctccgcctaccctgcaagagatg attcagatggcggcggagatcgccgacgggatggcctacctgaacgccaagaagtttgtg caccgggatctagcagcccgaaactgcatggtcgcccacgatttcactgtcaaaattgga gactttgggatgaccagagacatctatgagacggattactatcggaaaggaggcaagggt ctgctccccgtgcggtggatggcaccggagtccctgaaggacggggtctttaccacttct tctgacatgtggtcctttggcgtggtcctttgggaaatcaccagcttggcagagcagcct taccaaggcctgtctaatgaacaggtgttgaaatttgtcatggacggagggtatctggat caacccgacaattgtccagagagagtcactgacctgatgcgcatgtgctggcagttcaat cccaagatgcggcccaccttcctggagattgtcgacctgctcaaggatgatctgcacccc agctttccagaagtttccttcttccacagcgaggagaacaaggcacccgagagcgaggag ttggagatggagtttgaggacatggagagtgtccctctggatcgggcctcacactctcag agggaggaggccgggggccgggatgcagggtcctcgctgggcctaaagcggagctacgag gagcacatcccctacactcacatgaacgggggcaagaaaaatggacggattctgactctg ccaaggtcgaatccttcctaa

DBGET integrated database retrieval system