Canis lupus familiaris (dog): 486025
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Entry
486025 CDS
T01007
Symbol
FLT3
Name
(RefSeq) receptor-type tyrosine-protein kinase FLT3 precursor
KO
K05092
fms-related tyrosine kinase 3 [EC:
2.7.10.1
]
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa04010
MAPK signaling pathway
cfa04014
Ras signaling pathway
cfa04151
PI3K-Akt signaling pathway
cfa04640
Hematopoietic cell lineage
cfa05200
Pathways in cancer
cfa05202
Transcriptional misregulation in cancer
cfa05221
Acute myeloid leukemia
cfa05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
486025 (FLT3)
04014 Ras signaling pathway
486025 (FLT3)
04151 PI3K-Akt signaling pathway
486025 (FLT3)
09150 Organismal Systems
09151 Immune system
04640 Hematopoietic cell lineage
486025 (FLT3)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
486025 (FLT3)
05202 Transcriptional misregulation in cancer
486025 (FLT3)
05230 Central carbon metabolism in cancer
486025 (FLT3)
09162 Cancer: specific types
05221 Acute myeloid leukemia
486025 (FLT3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
cfa01001
]
486025 (FLT3)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
cfa04090
]
486025 (FLT3)
Enzymes [BR:
cfa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
486025 (FLT3)
Protein kinases [BR:
cfa01001
]
Receptor tyrosine kinases (RTK)
PDGFR family [OT]
486025 (FLT3)
CD molecules [BR:
cfa04090
]
Proteins
486025 (FLT3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
ig
Ig_3
I-set
Ig_2
Haspin_kinase
APH
Motif
Other DBs
NCBI-GeneID:
486025
NCBI-ProteinID:
NP_001018647
Ensembl:
ENSCAFG00000006716
VGNC:
40908
UniProt:
Q4ZHV8
LinkDB
All DBs
Position
25:11657250..11733707
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AA seq
993 aa
AA seq
DB search
MPALARRGGRLPLLVVFSAMIFEAITNQDLPVIKCVLINHKNNDSSLGLSSSYPTASEPP
EDLGCALKPESTEAVYGAATVEVDMSASITLQVLVNTPGNISCLWVFKHSSLNCQPHFDL
QNRGVVSMVILKMTETQAGEYLLFIQSGATNYTILFTVSIRNTLLYTLRRPYFRKMENQD
ALVCISESIPEPTVEWVFCDSQSESCKGESPAVVTKEESVLHELFGTDIRCCARNELGRE
CTKLFTIDLNQTPQTTPPQLFLKVGEPLWIRCKAVHINHGFGLTWELENKALEEGSYFEM
STYSTNRTMIRILFAFVSSVGRNDTGYYTCSSSEHPSKSALVTILEKGFINASKSSEDYE
IDQYEEFCFSVRFKAYPQIRCTWTFSRKSFPCEQSGLDDGYSISKFCNHKHQPGEYIFHA
ENDDAEFTKMFTLNIRRKPQVQANTSASQASCSSDGYPLPSWTWKKCSDKSPNCTEEITE
GIWNKKANRKVFGQWTSSSTLNMSEAVKGFLVKCCAYNSLGTSCETILLNSPGPFPFIQD
NVSFYATVGLCLPFIAILTMLICHKYKKQFRYESQLQMVQVTGSLDNEYFYIDFREYEYD
LKWEFPRENLEFGKVLGSGAFGKVMNATAYGISKTGVSIQVAVKMLKEKADSSEREALMS
ELKMMTHLGNHENIVNLLGACTLSGPIYLIFEYCCYGDLLNYLRNKREKFHRTWTEIFKE
HNFSFYPTFQSHPNSSMPGSREVQIQQDLDHISGLNGNSFQSEDEIEYENQKRLEEEEDL
NVLTFEDLLCFAYQVAKGMEFLEFKSCVHRDLAARNVLVTHGKVVKICDFGLARDIMSDS
NYVIRGNARLPVKWMAPESLFEGIYTIKSDVWSYGILLWEIFSLGVNPYPGIPVDANFYK
LIQSGFKMDQPFYATEEIYFIMQSCWAFDSRKRPSFPNLTSFLGCQLADAEEAMYQNMDG
HVSDRPSVYQNRRPYSREVDSGLLAPQAHVEES
NT seq
2982 nt
NT seq
+upstream
nt +downstream
nt
atgccggcgttggcgcgccgcggcggccggctgccgctgctcgttgttttttcagcaatg
atatttgaggctattacaaatcaagatctgcctgtgatcaagtgtgttttaatcaatcat
aagaacaatgattcatcactgggattatcatcatcttatcccacggcatcagaaccccca
gaagacctcgggtgtgccctgaagcctgagagcacagaggcagtgtatggagcagccact
gtggaagtggacatgtctgcatccatcacactgcaagtactggtcaacaccccggggaac
atttcctgtctctgggtctttaaacacagttccctgaattgccagccccactttgattta
caaaacagaggagttgtttccatggtcattttgaaaatgacagaaacccaagctggagaa
tatctactcttcattcagagtggagctaccaattacacaatattgtttacagtgagtata
agaaatacactgctttacacattaaggagaccttactttagaaaaatggaaaatcaggat
gccctagtctgcatatccgagagcattccagaaccgactgtggaatgggtgttctgcgat
tcacagagtgaaagctgtaaaggggaaagtccagctgttgttacaaaggaggaaagcgta
cttcatgaactgtttggaacagacataaggtgctgtgcaagaaatgagctgggcagggag
tgtaccaagctgttcacaatagatctaaatcaaactcctcagaccaccccgccacaatta
tttcttaaggtaggggagcccttatggataaggtgcaaagctgttcacataaaccacgga
ttcggactcacatgggagctagaaaataaagccctggaggagggcagctactttgagatg
agtacctattccacaaacagaactatgatacggattctgtttgcttttgtatcatcagtg
ggaagaaacgacactggctattacacttgttcctcttcagaacatcccagtaaatcagct
ttggttaccatcctagaaaagggatttataaatgcttccaaatcaagtgaggattatgag
attgaccagtatgaagagttttgtttttctgtcaggtttaaagcatacccacagatcaga
tgtacatggaccttctctcgaaaatcgtttccttgtgaacaaagtggcctcgatgatggg
tacagcatatctaagttttgcaaccataaacaccagccaggagaatatatattccatgca
gaaaatgatgatgccgaattcacaaaaatgttcacactgaacataagaaggaaacctcag
gtgcaagccaacacatcagcaagtcaggcttcttgctcctctgatggatacccattacca
tcttggacctggaagaaatgttcagacaagtctcccaactgcacggaggaaatcacagaa
ggaatttggaataaaaaggctaacagaaaagtatttggacagtggacatcgagcagtact
cttaacatgagtgaagctgtaaaaggattcctggtgaagtgctgtgcatacaattccctt
ggcacatcttgtgaaacaatccttttaaactcaccagggcccttccctttcatccaagac
aacgtctcgttctatgcaacagttgggctctgtcttcccttcattgcaattctaaccatg
cttatttgtcacaagtacaaaaagcaatttaggtatgaaagccagctgcagatggtacag
gtgacgggctctttggataatgagtacttctacattgatttcagagaatatgaatatgat
ctcaaatgggagtttcccagagaaaatttagaatttgggaaggtactaggatcaggtgct
tttggaaaagtgatgaatgcaacagcttatggaattagtaaaacaggagtctccatccag
gtggcagtcaaaatgctgaaagaaaaggcagacagttctgaaagagaggctctcatgtct
gaactcaaaatgatgactcacctgggaaaccacgagaatatcgtgaatctactgggggca
tgcacgctgtcaggaccaatttacttgatttttgaatattgttgctatggtgatcttctc
aactatttaagaaataaaagagaaaagtttcacaggacatggacggaaattttcaaggaa
cacaatttcagtttttaccccactttccaatcacatccaaattccagtatgcctggttca
agagaagttcagatacaacaggacttggatcacatctcagggctcaatgggaattcattt
caatctgaagatgaaatagaatatgaaaaccaaaaaaggctggaggaagaggaggaccta
aatgtgctgacatttgaagaccttctttgcttcgcatatcaagttgccaaaggaatggaa
tttctggaatttaagtcgtgtgttcacagagacctggcagccaggaatgtgctcgtgacc
catgggaaagtggtgaagatctgtgattttggattggctcgagatattatgagcgactcc
aactatgttatcaggggcaatgcccgtctgcctgtaaagtggatggcccctgaaagctta
tttgaagggatctacaccataaagagtgacgtctggtcatatggaatattactctgggaa
atattctctcttggtgtcaatccttaccctggtattccagttgatgctaacttctataaa
ctcattcaaagtggatttaagatggatcagccattttatgctacagaagaaatatacttt
ataatgcaatcctgctgggcttttgactcaaggaaacggccgtccttccccaacttaact
tcctttttaggatgtcagctggcggatgcagaagaagcgatgtatcagaacatggatggc
catgtttcagaccgtccttccgtctaccaaaacaggcgaccttacagcagagaggtggat
tcagggctacttgctccacaggctcatgttgaagagtcctag
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