Canis lupus familiaris (dog): 488508
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Entry
488508 CDS
T01007
Symbol
ERBB4
Name
(RefSeq) receptor tyrosine-protein kinase erbB-4 isoform X3
KO
K05085
receptor tyrosine-protein kinase erbB-4 [EC:
2.7.10.1
]
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa04010
MAPK signaling pathway
cfa04012
ErbB signaling pathway
cfa04020
Calcium signaling pathway
cfa04151
PI3K-Akt signaling pathway
cfa05014
Amyotrophic lateral sclerosis
cfa05205
Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
488508 (ERBB4)
04012 ErbB signaling pathway
488508 (ERBB4)
04020 Calcium signaling pathway
488508 (ERBB4)
04151 PI3K-Akt signaling pathway
488508 (ERBB4)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
488508 (ERBB4)
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
488508 (ERBB4)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
cfa01001
]
488508 (ERBB4)
Enzymes [BR:
cfa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
488508 (ERBB4)
Protein kinases [BR:
cfa01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
488508 (ERBB4)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
TM_ErbB1
Kinase-like
Haspin_kinase
ABC1
Motif
Other DBs
NCBI-GeneID:
488508
NCBI-ProteinID:
XP_003434325
Ensembl:
ENSCAFG00000023258
VGNC:
40437
UniProt:
A0A8C0NVA0
LinkDB
All DBs
Position
37:complement(19902993..21014297)
Genome browser
AA seq
1292 aa
AA seq
DB search
MKLAAGPWVWVSLLLAAGTVQPNASQSVCAGTENKLSSLSDLEQQYRALRKYYENCEVVM
GNLEITSIEHNRDLSFLRSIREVTGYVLVALNQFRYLPLENLRIIRGTKLYEDRYALAVF
LNYRKDGNFGLQELGLKNLTEILNGGVYVDQNKFLCYTDTIHWQDIVRNPWPSNLTLVST
NGSSGCGRCHKSCTGRCWGPTENHCQTLTRTVCAEQCDGRCYGPYVSDCCHRECAGGCSG
PKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNFNAKYTYGAFCVKKCPHNFVVD
SSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLMSAQTVDSSNIDKFINCT
KINGNLIFLVTGIHGDPYNAIEAIDPEKLNVFRTVREITGFLNIQSWPPNMTDFSVFSNL
VTIGGRVLYSGLSLLILKQQGITSLQFQSLKEISAGNIYITDNSNLCYYHTINWTTLFST
INQRIVIRDNRKAENCTAEGMVCNHLCSSDGCWGPGPDQCLSCRRFSRGRSCIESCNLYD
GEFREFENGSICVECDPQCEKMEDGILTCHGPGPDNCTKCSHFKDGPNCVEKCPDGLQGA
NSFIFKYADQDRECHPCHPNCTQGCSGPTSHDCIYYPWTGHSTLPQHARTPLIAAGVIGG
LFILVIVGLTFAVYVRRKSIKKKRALRRFLETELVEPLTPSGTAPNQAQLRILKETELKR
VKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHL
VRLLGVCLSPTIQLVTQLMPHGCLLDYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLV
HRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQ
SDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMID
ADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSKFFQNLLDEEDLEDMMDAE
EYLVPQAFNIPPPIYTSRARIDSNRNQFVYRDGGFAAEQGVPVPYRATTSTIPEAPVAQG
ATAEIFDDSCCNGTLRKPVAPHVQEDSSTQRYSADPTVFAPERSPRGELDEEGYMTPMRD
KPKQEYLNPVEENPFVSRRKNGDLQALDNPEYHNASNGPPKAEDEYVNEPLYLNTFANAL
GNAEYLKNNVLSVPEKAKKAFDNPDYWNHSLPPRSTLQHPDYLQEYSTKYFYKQNGRIRP
IVAENPEYLSEFSLKPGTVLPPPPYRHRNTVV
NT seq
3879 nt
NT seq
+upstream
nt +downstream
nt
atgaagctggcggcaggaccgtgggtctgggtgagccttctgctggcagcggggaccgtc
cagcccaacgcctcccagtcagtgtgtgcaggaacagagaacaagctgagctctctctct
gacctggagcagcagtatcgagctttgcgcaaatactatgagaactgtgaggtggtcatg
ggcaacctggagataaccagcatcgagcacaaccgggacctctcctttctgcggtctatt
cgggaagtcacaggctacgtgttagtggctcttaatcagtttcgttacctgcctctggag
aatttacgcattatccgtgggacaaaactttatgaggatcgatatgccttggcagtattt
ttaaactacagaaaagatgggaactttggacttcaagaacttggattgaagaatttgaca
gaaatccttaatggtggagtatatgtagaccagaacaaatttctctgttacacagacaca
attcattggcaagatattgttcggaatccatggccttccaacttgactctggtatcaaca
aatggtagctcaggatgtggacgttgtcataagtcctgtactggccgatgctggggaccc
acagaaaatcattgccagaccttgacaaggacggtgtgtgcagaacagtgtgatggcagg
tgctatgggccctatgtcagtgactgctgtcatagagaatgtgctgggggctgctcagga
cctaaggacacagactgctttgcctgcatgaatttcaatgacagtggagcatgtgttact
cagtgtcctcaaacttttgtctataatccaaccacctttcaactggagcataacttcaat
gcaaagtatacatatggagcattttgtgtcaagaaatgtccacataactttgtggtggat
tccagttcttgtgtgcgtgcctgccctagttccaagatggaagtagaagaaaatgggatt
aaaatgtgtaaaccttgcactgatatttgcccaaaagcttgtgatggcatcggcacagga
tcattgatgtcggctcagactgtggattccagtaacattgacaaattcataaactgcacc
aaaatcaatgggaatttgatcttccttgtcactggtattcatggggacccttacaatgca
attgaagccatagacccagagaaactgaatgtcttccgcacagttcgagagataacgggt
ttcttgaacatacagtcatggcctccaaacatgaccgacttcagtgttttttccaacctg
gtgaccattggtggaagagtactctatagtggcctctccttgcttatccttaagcaacag
ggcatcacttctctacaattccaatccctgaaggaaatcagtgcgggaaacatctatatt
actgacaacagcaacctgtgttattaccataccattaattggacaacactcttcagcact
atcaaccaaagaatagtgatccgggataacaggaaagctgaaaactgtactgctgaagga
atggtgtgcaaccatctgtgttcaagcgatggctgttggggacctggccccgaccagtgc
ctgtcctgccgtcgcttcagcagaggaaggagctgcatagagtcttgtaacctctatgac
ggtgaatttcgagagtttgagaatggctccatctgtgtggagtgtgacccccagtgtgag
aagatggaagatggcatcctcacctgccatggaccgggacctgacaactgcacaaagtgc
tcccattttaaggatggcccgaactgtgtggaaaaatgtccagatggcttacagggggca
aacagttttattttcaagtatgctgatcaggatcgggagtgccacccatgtcatccaaac
tgcacccaagggtgtagcggtcccactagtcatgactgcatttattatccttggacgggc
cattccactttaccacaacatgctagaactcctctaattgcagcgggagtcatcggtggg
ctcttcatcctggtcatcgtgggtctaacatttgcagtttatgttagaaggaagagcatt
aaaaagaaaagagccttgagaaggtttctggaaacagagttggtagaacccttaactccc
agtggcacggcgcccaatcaagctcaacttcgtattttgaaagaaactgagcttaaaaga
gtgaaagtacttggctcaggtgcttttggaacagtttataaaggtatctgggtacctgaa
ggagaaacagtaaagattcctgtggctattaaaattcttaatgaaacaactggtcccaaa
gccaatgtggaattcatggatgaagctttgatcatggcaagtatggaccatccacactta
gtccggttattgggtgtgtgtctgagcccaaccattcagctggttacacagcttatgccc
catggttgcctgttggattatgtccatgaacacaaggataacattggatcccagctgctg
cttaactggtgtgtccagatagctaaggggatgatgtacctggaagaaagacgacttgtt
catcgggacttggcagcccgaaatgtcttagtgaaatctccaaaccatgtgaaaatcaca
gattttggactagccagactcttagaaggagatgaaaaagagtataatgctgatggagga
aagatgccaattaaatggatggctctcgagtgtatacactatagaaaattcacccatcag
agtgatgtttggagctatggagtcactatatgggaactgatgacatttggaggaaaaccc
tacgatggaattccaacccgagaaatccctgatttattagagaaaggagaacgtttgccg
cagcctcctatctgcactattgacgtttacatggtcatggtcaaatgttggatgattgat
gctgacagtaggcctaaatttaaggaactggctgctgagttttcgaggatggctcgagac
cctcaaagatatctagtcattcagggtgacgatcgcatgaagcttcccagtccaaatgac
agcaagttctttcagaatctcttggatgaagaggatttggaagacatgatggatgctgag
gaatacttggtccctcaggcgttcaacattccacctcccatctacacttccagagcaaga
attgactcaaataggaaccagtttgtataccgagatgggggttttgctgcagaacaagga
gtgcctgtgccctacagagccacgaccagcacgattccagaagctccagttgctcagggg
gctacagctgagatttttgatgactcctgttgtaatggcaccctacgcaagccagtggca
ccccatgtccaagaggatagcagcacccagaggtacagcgctgatcccactgtgtttgcc
ccagaacgaagcccacgaggagagctggatgaagaaggttacatgacccctatgcgagat
aaacctaaacaagaatacttgaaccctgtggaggagaacccttttgtttctcggaggaag
aatggagaccttcaagctttggataatcccgaatatcacaatgcttccaatggtccaccc
aaggcagaggatgagtatgtgaatgagccactgtacctcaacacctttgccaacgcattg
gggaatgccgaatacctgaagaacaatgtactgtctgtgccagagaaggccaagaaagca
ttcgacaaccctgactactggaaccacagcctgccacctcggagcacccttcagcaccca
gactacctgcaggagtacagcacaaaatatttttataaacaaaatggacggatccggcct
attgtggcagagaatcctgaatacctctctgagttctcgctgaagccaggcactgtgctg
cctcctccaccctacagacaccgaaatactgtggtgtaa
DBGET
integrated database retrieval system
