Canis lupus familiaris (dog): 489159
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Entry
489159 CDS
T01007
Symbol
ITK
Name
(RefSeq) tyrosine-protein kinase ITK/TSK isoform X1
KO
K07363
IL2-inducible T-cell kinase [EC:
2.7.10.2
]
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa04062
Chemokine signaling pathway
cfa04660
T cell receptor signaling pathway
cfa04670
Leukocyte transendothelial migration
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09150 Organismal Systems
09151 Immune system
04660 T cell receptor signaling pathway
489159 (ITK)
04670 Leukocyte transendothelial migration
489159 (ITK)
04062 Chemokine signaling pathway
489159 (ITK)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
cfa01001
]
489159 (ITK)
Enzymes [BR:
cfa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
489159 (ITK)
Protein kinases [BR:
cfa01001
]
Non-receptor tyrosine kinases
TEC family
489159 (ITK)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
SH2
PH
SH3_1
BTK
SH3_9
SH3_10
SH3_2
PH_8
SH3_3
SH3_4
ABC1
Motif
Other DBs
NCBI-GeneID:
489159
NCBI-ProteinID:
XP_546277
Ensembl:
ENSCAFG00000017565
VGNC:
42149
UniProt:
A0A8C0N2M8
A0A8I3MMK2
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Position
4:complement(52795128..52858373)
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AA seq
620 aa
AA seq
DB search
MNNFILLEEQLIKKSQQKRRTSPSNFKVRFFVLTKTSLAYFENRHGKKRTLKGSIELSRI
KCVEIVKSDISIPCHYKYPFQVVHDNYLLYVFAPDRESRQRWVLALKEETKNNNSLVPMY
HPNFWMDGRWRCCAQMEKLAVGCAQYDPTKNASKKPLPPTPEDNRRSLREPEETIVIALY
DYQTNDPQELMLQRNEEYYLLDSSEIHWWRVQDRNGHEGYVPSSYLVEKSPNSLETYEWY
NKSISRDKAEKLLLDTGKEGAFMVRDSRTPGTYTVSVFTKAIVSENNPCIKHYHIKETND
NPKRYYVAEKYVFDSIPLLINYHQHNGAGLVTRLRHPVCSWRQKAPVTAGLRYGKWVIDP
TELTFVQEIGSGQFGLVHLGYWLNKDKVAIKTIQEGAMSEEDFIEEAEVMMKLSHPKLVQ
LYGVCLEQAPICLVFEFMEHGCLSDYLRNQRGLFAAETLLGMCLDVCEGMAYLEEACVIH
RDLAARNCLVGENQVIKVSDFGMTRFVLDDQYTSSTGTKFPVKWASPEVFSFSRYSSKSD
VWSFGVLMWEVFSEGKIPYENRSNSEVVEDITTGFRLYKPRLASSNIYQIMNHCWKEKPE
DRPPFCRLLSQLAEIAESGL
NT seq
1863 nt
NT seq
+upstream
nt +downstream
nt
atgaacaactttatcctcctggaagaacaactcatcaagaaatcacaacaaaagagaaga
acttctccctcaaactttaaagtccgtttctttgttttaaccaaaaccagcctggcatac
tttgagaatcgtcacgggaaaaagcgcacattgaagggctccattgaactctcccgaatc
aaatgtgtcgagattgtgaaaagtgacattagcatcccatgccactataaatatccattt
caggttgtgcatgacaactacctcctctatgtgtttgctccagaccgtgagagccggcag
cgctgggttctggcccttaaagaagaaacaaagaataacaacagtttggtgcccatgtac
catcctaatttctggatggatgggaggtggaggtgctgtgctcagatggagaagcttgca
gtgggctgtgctcagtacgatccaaccaagaatgcttcaaagaagcctcttcctcctact
cctgaagacaacaggcgatcacttcgggaacccgaagaaaccattgtcattgccttgtat
gactaccaaacaaatgacccacaggaactcatgctacaacgcaatgaggagtactacctg
ctggacagttccgagattcactggtggagggtacaggacaggaatgggcatgaaggatat
gtaccaagcagttatctggtggaaaagtctccaaatagcctggaaacctatgagtggtac
aataagagtatcagtcgagacaaagctgaaaaacttcttttagacacaggcaaagaagga
gccttcatggtacgagattccagaactccaggaacatatactgtatctgttttcaccaaa
gccattgtaagtgagaacaacccctgtatcaagcactatcacattaaagaaacaaatgac
aaccccaagcgatattatgtggctgagaagtacgtgtttgactccattcctctcctcatc
aattatcaccaacacaatggagcaggtctggtcactagactccggcacccagtttgttct
tggaggcagaaagcaccagtcactgcgggactgagatacgggaaatgggtgattgatccc
actgagctcacttttgtgcaggagattggcagtggacagtttgggctggtgcatcttggc
tactggcttaacaaggacaaggtggccatcaaaaccattcaagaaggggctatgtcagaa
gaggacttcatagaggaggctgaagtcatgatgaaactctctcaccccaaactggtccag
ctgtatggggtatgcctagagcaagctcccatctgcctggtgtttgagttcatggaacac
ggctgcctgtcagattatcttcgcaaccagcggggactctttgctgcagaaaccctactg
ggcatgtgcctggatgtgtgtgaaggcatggcctacttggaggaggcatgtgtcatccac
agagacctggctgccagaaattgtttagtgggagaaaaccaagtcatcaaggtgtccgac
tttgggatgacaaggtttgtccttgatgatcaatacaccagttccacaggcaccaagttc
ccggtgaagtgggcatccccagaagtcttctccttcagtcgctatagcagcaagtcagat
gtgtggtcatttggtgtgctaatgtgggaagtcttcagtgaaggcaaaatcccgtatgaa
aatagaagcaactcagaagtggtggaagacatcactactggatttcgcttatacaagccc
cggctggcctcctcgaatatctaccagataatgaatcattgctggaaagagaaaccagag
gaccggccacctttctgcagactcttgagtcaactggctgaaattgcagaatcgggactt
tag
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