Canis lupus familiaris (dog): 490382 Help Entry 490382            CDS       T01007                                  Symbol PSEN2 Name (RefSeq) presenilin-2   KO K04522   presenilin 2 [EC:3.4.23.-] Organism cfa  Canis lupus familiaris (dog) Pathway cfa04330   Notch signaling pathway cfa04722   Neurotrophin signaling pathway cfa05010   Alzheimer disease cfa05022   Pathways of neurodegeneration - multiple diseases Brite KEGG Orthology (KO) [BR:cfa00001]  09130 Environmental Information Processing   09132 Signal transduction    04330 Notch signaling pathway     490382 (PSEN2)  09150 Organismal Systems   09156 Nervous system    04722 Neurotrophin signaling pathway     490382 (PSEN2)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     490382 (PSEN2)    05022 Pathways of neurodegeneration - multiple diseases     490382 (PSEN2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:cfa01002]     490382 (PSEN2) Peptidases and inhibitors [BR:cfa01002]  Aspartic peptidases   Family A22: presenilin family    490382 (PSEN2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Presenilin Motif Other DBs NCBI-GeneID:  490382 NCBI-ProteinID:  NP_001271394 Ensembl:  ENSCAFG00000016039 VGNC:  45086 UniProt:  M1V4F1 LinkDB All DBs Position 7:complement(37629753..37654335) Genome browser AA seq 448 aa AA seqDB search MLTFMASDSEEEVCDERTSLMSAESPPPRCCQEARQGLEDGENAAQWRSQDSEEDFEDDA DHYVCGGVPGQPSGLEEELTLKYGAKHVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQLI YTPFTEDTPSVGQRLLNSVLNTLIMISVIVAMTIFLVVLYKYRCYKFIHGWLIMSSLMLL FLFTYIYLGEVLKTYNVAMDYPTLFLTVWNFGAVGMVCIHWKGPLVLQQAYLIMISALMA LVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVW TVGMAKLDPSSQGALQLPYDPEMEEDSYDSFREPSYPEVFEPPLPGYPGDELEEEEERGV KLGLGDFIFYSVLVGKAAATGSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALPISI TFGLIFYFSTDNLVRPFMDTLASHQLYI NT seq 1347 nt NT seq  +upstreamnt  +downstreamnt atgctcacattcatggcctctgacagtgaggaagaagtgtgtgacgagaggacatccctg atgtcggctgagagccccccgccacgctgctgccaggaggccaggcagggcctggaggat ggagaaaatgctgcccagtggagaagccaggacagcgaggaggactttgaggatgatgct gaccactacgtctgcggcggggtacctgggcagccgtcgggcctggaggaggagctgacc ctcaagtatggggcaaagcacgtgatcatgctctttgtgccggtcaccctgtgcatgatt gtggtggtggccaccatcaagtccgtgcgcttctacacagagaagaacggacagctcatc tacacaccattcaccgaggacacgccctctgtgggccagcgcctcctcaactctgtgctc aacaccctcatcatgatcagcgtcattgtggccatgaccatcttcttggtcgtgctctac aagtaccgctgctacaagtttatccatggctggttgatcatgtcatccttgatgctcctg ttccttttcacctatatctacctcggggaagtgcttaagacctacaacgtggccatggac taccctaccctgttcctgactgtctggaactttggggcagtgggcatggtgtgcatccat tggaaaggccccttggtgttgcagcaagcctacctcatcatgatcagtgccctcatggcc ttggtgttcatcaagtacctccccgaatggtctgcctgggtcattctgggcgccatctct gtgtacgatctagtggctgtgctgtgccccaaagggcctctgaggatgctggtggagacc gcccaggagagaaacgagcccatatttcctgccctgatatactcctctgccatggtgtgg acagtgggcatggccaagctggacccctcctcccagggagccctgcagctgccctacgac ccagagatggaagaagactcgtatgacagttttagggagccctcgtacccggaagtcttt gagccccccctgcctggttacccaggggacgaactggaggaagaggaggaaaggggcgtg aagctcggcctgggggacttcatcttctacagtgtgctggtgggcaaggcagcggccaca ggcagcggggactggaacaccacgctggcgtgcttcgtggccatcctcattggtttgtgt ctgaccctcctgctgcttgctgtgttcaagaaggcactgcctgccctccccatttccatc acatttgggctcatcttttacttctccacggacaacttggtgcgtccgttcatggatacc ttggcctcccatcagctctacatctga

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