Canis lupus familiaris (dog): 494010 Help Entry 494010            CDS       T01007                                  Symbol CYP1A2 Name (RefSeq) cytochrome P450 1A2 precursor   KO K07409   cytochrome P450 family 1 subfamily A2 [EC:1.14.14.1] Organism cfa  Canis lupus familiaris (dog) Pathway cfa00140   Steroid hormone biosynthesis cfa00232   Caffeine metabolism cfa00380   Tryptophan metabolism cfa00591   Linoleic acid metabolism cfa00830   Retinol metabolism cfa00980   Metabolism of xenobiotics by cytochrome P450 cfa00982   Drug metabolism - cytochrome P450 cfa01100   Metabolic pathways cfa05204   Chemical carcinogenesis - DNA adducts cfa05207   Chemical carcinogenesis - receptor activation cfa05208   Chemical carcinogenesis - reactive oxygen species Brite KEGG Orthology (KO) [BR:cfa00001]  09100 Metabolism   09103 Lipid metabolism    00140 Steroid hormone biosynthesis     494010 (CYP1A2)    00591 Linoleic acid metabolism     494010 (CYP1A2)   09105 Amino acid metabolism    00380 Tryptophan metabolism     494010 (CYP1A2)   09108 Metabolism of cofactors and vitamins    00830 Retinol metabolism     494010 (CYP1A2)   09110 Biosynthesis of other secondary metabolites    00232 Caffeine metabolism     494010 (CYP1A2)   09111 Xenobiotics biodegradation and metabolism    00980 Metabolism of xenobiotics by cytochrome P450     494010 (CYP1A2)    00982 Drug metabolism - cytochrome P450     494010 (CYP1A2)  09160 Human Diseases   09161 Cancer: overview    05204 Chemical carcinogenesis - DNA adducts     494010 (CYP1A2)    05207 Chemical carcinogenesis - receptor activation     494010 (CYP1A2)    05208 Chemical carcinogenesis - reactive oxygen species     494010 (CYP1A2)  09180 Brite Hierarchies   09181 Protein families: metabolism    00199 Cytochrome P450 [BR:cfa00199]     494010 (CYP1A2) Enzymes [BR:cfa01000]  1. Oxidoreductases   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen    1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor     1.14.14.1  unspecific monooxygenase      494010 (CYP1A2) Cytochrome P450 [BR:cfa00199]  Cytochrome P450, animal type   CYP1 family    494010 (CYP1A2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  p450 Sec8_N Motif Other DBs NCBI-GeneID:  494010 NCBI-ProteinID:  NP_001008720 Ensembl:  ENSCAFG00000017941 VGNC:  50333 UniProt:  Q5R2U2 LinkDB All DBs Position 30:37751388..37757086 Genome browser AA seq 512 aa AA seqDB search MALSQMATELLLASTIFCLVLWVVKAWQPRLPKGLKSPPGPWGWPLLGNVLTLGKSPHLA LSRLSQRYGDVLQIRIGSTPVLVLSGLDTIRQALVRQGDDFKGRPDLYSFSLVTDGQSLT FSPDSGPVWAARRRLAQNALNTFSIASDPASSCSCYLEEHVSKEAEALLSRLQEQMAEVG RFDPYNQVLMSVANVIGAMCFGHHFSQRSEEMLPLLMSSSDFVETVSNGNPVDFFPILQY MPNSALQRFKNFNQTFVQSLQKIVQEHYQDFDERSVQDITGALLKHNEKSSRASDGHIPQ EKIVNLINDIFGAGFDTVTTAISWSLMYLVANPEIQRKIQKELDTVIGRARQPRLSDRPQ LPLMEAFILEIFRHTSFVPFTIPHSTTKDTTLKGFYIPKECCVFINQWQVNHDQQVWGDP FAFRPERFLTADGTAINKTLSEKVMLFGMGKRRCIGEVLAKWEIFLFLAILLQRLEFSVP AGVRVDLTPIYGLTMKHTRCEHVQARPRFSIK NT seq 1539 nt NT seq  +upstreamnt  +downstreamnt atggcattgtcccagatggccacagagcttctcctggcctccaccatcttctgcttggta ctctgggtggtcaaggcctggcagcctcggcttcccaaaggcctgaagagtccaccgggg ccctggggctggcccctgctcgggaacgtgctgaccttgggcaagagcccccacctggcg ctgtccaggctgagccagcgttatggggacgtgctgcagatccgcatcggctccaccccc gtgctggtgctcagtggcctggacaccatccggcaggccctggtgcgccagggggatgat ttcaagggccggcccgacctctacagcttctctctggtgaccgacggccaaagcctgacc ttcagcccagactccggaccagtgtgggctgcgcgcaggcgcctggctcagaacgcgctc aacaccttctccattgcctccgacccggcttcctcgtgctcttgctacctggaagagcat gtgagcaaggaggccgaggcccttctcagcaggctgcaggagcagatggcagaggttggg cgctttgatccctacaaccaagtgctgatgtcagtggccaatgtcattggtgcaatgtgc tttgggcaccacttctctcagagaagtgaggaaatgctccccctcctaatgagctccagt gattttgtggagaccgtctccaacgggaacccggtggactttttccccattctccaatat atgcccaactcagccctgcagagattcaagaacttcaaccagacgttcgtgcagtccctg cagaaaattgtccaggaacactatcaagactttgatgagcgcagtgtccaggacatcaca ggcgccctcttgaagcacaatgagaagagctccagggctagtgatggccacatcccccaa gagaagattgtcaaccttatcaacgacatttttggggccggatttgacactgtcacaacg gccatttcctggagtcttatgtaccttgtggcaaaccctgagatacagagaaagatccag aaggagttggacacggtgattggcagggcacggcagcctcgcctctctgacaggccccag ctgcccttaatggaggccttcatcctggagatcttccgacacacctcctttgtccccttc accatcccccacagcacaacaaaggacacaaccttaaagggcttctacatccccaaggaa tgctgtgtcttcataaaccagtggcaggtcaatcatgaccaacaggtgtggggggatcca tttgcattccggccagagcgattcctcactgcagatggcaccgccatcaacaagaccttg agtgagaaggtgatgctctttggcatgggcaagcgccggtgcataggagaggtcctggcc aagtgggagatcttcctcttcctagccatcttgctgcagcggctggagttcagcgtgcca gcaggtgtgagagtagacctaacccccatctatgggctgaccatgaagcacacccgctgt gagcatgtccaggcacggccacgcttctccatcaagtga

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