Canis lupus familiaris (dog): 607879 Help Entry 607879            CDS       T01007                                  Symbol ESPL1 Name (RefSeq) separin   KO K02365   separase [EC:3.4.22.49] Organism cfa  Canis lupus familiaris (dog) Pathway cfa04110   Cell cycle cfa04114   Oocyte meiosis cfa05166   Human T-cell leukemia virus 1 infection Brite KEGG Orthology (KO) [BR:cfa00001]  09140 Cellular Processes   09143 Cell growth and death    04110 Cell cycle     607879 (ESPL1)    04114 Oocyte meiosis     607879 (ESPL1)  09160 Human Diseases   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     607879 (ESPL1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:cfa01002]     607879 (ESPL1)   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:cfa03036]     607879 (ESPL1) Enzymes [BR:cfa01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.49  separase      607879 (ESPL1) Peptidases and inhibitors [BR:cfa01002]  Cysteine peptidases   Family C50: separase family    607879 (ESPL1) Chromosome and associated proteins [BR:cfa03036]  Eukaryotic type   Sister chromatid separation proteins    Separase     607879 (ESPL1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Separin_C Motif Other DBs NCBI-GeneID:  607879 NCBI-ProteinID:  XP_005636831 Ensembl:  ENSCAFG00000007030 VGNC:  40475 UniProt:  A0A8C0TIR5 A0A8I3S1V2 LinkDB All DBs Position 27:44314872..44338083 Genome browser AA seq 2108 aa AA seqDB search MRSFKGIDFGTLLSNPKEAEELLPDLKEFLSKLPAGSPSCRSDAERRRACDAILRACNQQ LTARLACPRHLESLLDLAELACDGYVVFTPQRSPLYLERILFIFLRNIATQGIPEATLRF AQPLHACLVQCSRQAAPQDYEAVARGSFSLLWKAAEGLEDQRAAFSARLKALSFLVLLED ESTPCEVPYFASPTAYRVAVAHQLFDATGHDLNEADADFLDDLLSRHVIKALVGEGGGPP GPLSPQRALCLLELTLEHCRRLCWSCHHAKATRVVEKAHEYLRDTDLAPSLQLCQLVVEL LQTGEGEPQALAKLLITASTILNNSVEAPSPPLRALCDSCQFFLSALERGIKRRYGPDAV LGLFAFLRGYYSLIRQLQDSVGGDSSKQRQSLIQMQFQGLHLYTVVVYDFAQGCQVAQVA DLAQLVESCKSTVAWMLEVLQSLSGQELTDYLGMTASYTSNLAYSFYSHKLYAEACAISE PLCQHLGLAKLGTYPELPPEKLHRCFRLHGESLKKLGKQAEGCTMVTLWLAALRPCGPQH MAEPVTFWVRVKMDAARAGDKELQLRTLRDSLSAWDPETLVFLLREELQAYKAVRADTGQ ERFNVICDLLELSPEETPAGAWARATHLVELAQVLCYHDFAQQTNCSALDAIQEALQLLE SVRPETQAQDQLLDDKAQALLWLYICTLEAKMQEGIERDRRAQAPNNLEEFEVNDLNYED KLQEDRFLYSNIAFNLAADAAQSKCLDQALALWKEVLTKAQAPAVRCLQQTLASLQTLAA LYQLAAKPLQALEVLQLVRIVSQRLEDHAKAAGSSCHTTQLLLTLGCPSYAQLHLEKADA SLKLLDHTTDTYLLLSLTCDLLRSHLYCVHQKVPEGAALLLSVLRDPALQRPSKAWYLLR VQALQLVACYLGLSSHSLPAPLREQLCTQGWQTPEIALIDSHKLLRSIILLLMGSDVLST QKAAVETPFLDSGENLVQKWQVLTEVLSCSETLVSRLGQLGSVSEAKAFCLEALKLTTKL QMPRQCALFLVLKAELELARNDLDLCQSDLQQVLFLLESCTDFGGLAQPLDSVKKVHLQK GKQQAQAHRPPELPEEEPFLRGPALELVATVAKEPGPVVPSTNSSPILKVRTPPSAGFLT HLPTCDCLLCASPVLSAVCLRWALVTARVRLATGHQAQGLDLLQAVLNGCPAATERLTQA LQASLNHKAPLSPVPRLLDEILAQAYTQLALEGLSRPSNKSLGKVLQSALRFVAAQAPHL EPWRASLLWVRALAKLAALNCCAAQLFASSWGWQPPSVKSPPGSEPSKPRSQKHSGREHQ QAASCTPSLRNTSLKGPEGGGLPCTPKPRGQARQAGPRVPFTVFEEVLSTKSKPEVPKAP RVQQRVQTRLKVNFSDDSDLEDRVSVEAQLAEGPKRRGTASQGRGRARKGSGLKTVSVAA PASAPRRPGLSGRSQRAKKVTPGHREELGPEIMRTIPAEEMTDDQMELSFEILRGSDGED STLDGKAPAPGPDTAIGECEVLRRDSSKEELPIPRPDKERDKDFGPRLRLPSAPTAIGVS TLDSICDLLTVAFRGVSHCPPSGLYAHLCRILALCLGHRDPCATACLVTESVSITCRHQL LTHLHRQLSKAQKHRGSLEMAEELQRLSLEEKPRDVPLARIQHLFSFGASGSGQFPEPEK ESFQERLALIPRGVTVCVLALATLQPGTVGNTLLLTRLEKDNPPVTVQIPTAQSKLPLSA ALKEFDAIQKEQKENSNCTDKREWWTGRLELDHRMEALITSLEKHVLGCWRGLLLPSSDD PGPAQEASRLQELLQECGWKYPDPTLLKIMLHSARTLAPEDIQTLAYGLCPAQPERAQEL LSEAVGRLQGQTVPSNRHLVLVLDKDLQKLPWESMPSLRALSVTRLPSFRFLLSYSIIKE SGASSVLSQGVDPRNTFYVLNPHNNLSSTEEQFRANFSSEAGWKGVVGERPSPEQIQAAL TEHDLYIYAGHGAGARFLDGQAVLRLSCRAVALLFGCSSAALAVHGSLEGAGIVLKYIMA GCPLFLGNLWDVTDRDIDRYTEALLQGWLRAGPGAPLLYYVNQARQAPRLKHLIGAAPVA YGLPVCLR NT seq 6327 nt NT seq  +upstreamnt  +downstreamnt atgagaagcttcaaaggaatcgacttcgggaccttgctaagcaacccaaaggaggctgaa gaattgctgcctgacttgaaggagttcctgtccaagcttccagctggttcacccagctgc cgatctgatgccgagaggagacgagcatgtgatgccatcttgagggcttgcaaccagcag ctgacagccaggctggcttgccctaggcacctggagagtctgctggacctggcagagctg gcttgcgatggctacgtggtgttcaccccccagcgctcacccctctacctggaacgaatt ctcttcatctttcttcggaacattgccacacagggaatcccagaggccacacttcgattc gcgcagcccctccatgcctgtttggtgcagtgctctcgccaagctgctccccaggactat gaggctgtggcccgcggcagcttttctctgctttggaaggcggcagaaggcctggaggat cagcgggctgcattctcggctcggctgaaggccttgagttttctggtgctcttggaggat gaaagtaccccttgtgaggttccctactttgcttctccaacagcctatcgagtggcagtt gcccatcagctatttgatgccactgggcatgatctgaatgaagcagatgctgatttccta gatgacctgctctccaggcatgtgatcaaagccttggtgggtgagggagggggtcctcct ggtcctctctctccccagagggccctctgtctcttggaactcaccctggaacactgccgt cgcctctgctggagctgccaccatgccaaggctaccagggtagtggagaaggcccacgaa tacctaagggacaccgatttggcccccagcctccagttatgccagcttgtggttgaactg ctacagaccggggagggagaacctcaggctctggccaagcttctgatcacggcatcaact atcctgaacaacagcgtggaggccccatcaccccctctgcgggcattgtgtgacagctgc cagttcttcctctcagccctggagcgaggcatcaagaggcgctatggacctgatgctgtt ctgggcctctttgcttttctcaggggctactattctctcatccggcagctgcaggacagt gtcggtggggactcctccaagcagcggcagtctttaatccagatgcagtttcagggactt catctctacactgtagtggtttatgactttgcgcaaggctgtcaggtagctcaagtggct gacctggcccagctagtggaaagttgcaaatctactgtggcctggatgctggaggtctta cagagcctgtcaggccaagagctgactgactacctgggcatgactgcctcctacaccagt aacttggcctacagcttctatagtcacaagctgtacgccgaggcctgtgccatctctgag cccctctgtcagcacctgggcttggcgaagctgggcacctatcctgagttgcctcctgag aagttgcacagatgcttccggctgcacggagagagtttgaagaaactgggtaagcaggcc gagggctgcacgatggtgactttgtggctggcggccctgcggccctgtggcccccagcac atggctgagccagtcaccttctgggttcgggtcaagatggatgcagccagagcaggagac aaggagctacagctgaggaccctgcgagacagcctgagtgcctgggacccggagaccctg gtcttcctgctgagggaagagctgcaggcctataaggctgtgcgagcggacacggggcag gagcggttcaacgtcatctgtgacctgttggaactgagccctgaggagacaccggctggg gcctgggctcgagccacccacctggtggaactggctcaggtgctctgctaccacgacttt gcccagcagaccaactgctctgccctggatgctatccaggaagccctgcagcttctagag tctgtgaggcccgagacccaggcccaggatcagcttctagatgataaagcacaggccctg ctgtggctctacatctgcactctggaggccaagatgcaggagggtatcgagcgggatcgg agagcccaggcccctaataacctggaggaatttgaagtcaatgacctgaactatgaagat aaactgcaggaagaccgcttcctgtacagtaacatcgccttcaacctcgctgcagatgct gctcagtccaaatgcctggaccaagccctggccctgtggaaggaggtgcttacgaaggca caggcgcctgctgtccgttgtctccagcagacactggcctctctgcagaccctagcagcc ctctatcagctggcggcaaagcccctgcaggccctggaggtcctccagcttgttcggatc gtctcccagaggttggaagatcacgcaaaggcagctggctcctcctgccacactacccag ctgctcctgacgctcggctgtcccagctatgcccagctgcacctggaaaaggcagacgcc agcctgaagcttctggatcacaccactgacacgtacttgctcctttcgctgacctgtgac ctgcttcgaagtcacctctactgtgttcaccagaaggtgcccgagggcgccgctctgctg ctgtccgtgctgcgggaccccgccctccagcggccgtccaaggcctggtatctgctgcgt gtccaggccctgcagctggtggcctgctacctcggcctctcgtcacacagcctgccggcc cccctgcgggagcagctctgcacccaaggctggcagacacccgagattgcactcatcgac tcgcataagctcctccgaagcatcatcctcctgcttatgggcagcgacgtgctctcgacg cagaaggcagctgtggagaccccgttcctggactccggggaaaatctggttcagaagtgg caggttctgaccgaggtgctgagctgctcagagacgctggtctcccgcctgggccagctg ggcagcgtgagcgaagccaaggccttttgcttggaggccctgaaactcacgacgaagctg cagatgccacgccagtgcgccctgttcctggtgctgaaggcggagctggagctggcacgc aacgacctcgacctctgccagtcggacctgcagcaggttctgttcttgctggagtcttgc acagactttgggggactagcccagcccctggactctgtgaagaaggtgcacctgcagaag ggcaagcagcaggcccaggcacaccgtcctccggagcttccagaagaggagcccttcctc agaggccctgctctggagctggtagccactgtggccaaggagcctggccccgtagtgcct tctactaactcttcccctatcctgaaggtgaggaccccgcccagcgccggcttcctgacc cacctgcccacgtgtgactgcctcctctgtgccagccctgtcctctcggcagtctgtctg cgctgggcattggtcaccgcgagggtgcggctggccacgggccatcaggcccagggtctg gatctgctgcaggccgtgctgaacggatgccctgcagccaccgagcgcctcacccaagct ctgcaggcttccctgaatcacaaagcacccctgtcccctgtcccgaggcttctggatgag atcctggctcaggcctacacacagctggcactggaggggctgagccgcccgtcaaacaag agcctggggaaggtcctgcagtcagcgctgaggtttgtggcagcgcaggctccccacctg gagccttggcgagccagcctgctctgggttcgggccctggcaaagctggctgccctcaac tgttgcgcggcccaactttttgcaagctcctggggctggcagcccccgtccgtgaaatcg cccccaggctcagagccgtctaagcctcggagtcaaaaacattctggaagagagcatcaa caggcagcctcttgcaccccgtccctccgtaacacctctctgaaaggtccggaaggtgga ggactgccctgcacacctaagccccggggccaggccaggcaggcaggccctcgtgtccct ttcaccgtgtttgaggaagtcctctctacaaagagcaagcctgaggttcccaaggccccc agggtacaacagagggtccagacgcgactcaaggtgaacttcagcgatgacagtgacttg gaagaccgggtctcagttgaggcacagcttgcagaggggcccaagagacggggcactgct tcccagggccggggccgggccaggaagggctcgggcttgaagactgtttcagtggcagcc ccagctagtgccccccggcgccctggcctcagtggcaggagccagagggccaagaaggtg acaccagggcaccgtgaagagctgggccctgagatcatgaggaccatccccgcggaggaa atgactgacgaccagatggaactgagctttgagatccttaggggctctgatggagaagac tctaccttagatgggaaggcacccgctccaggacctgacacggccataggcgaatgtgag gtgttgagacgtgattccagcaaagaggagctgcccatcccacgcccagacaaggagaga gacaaggacttcggtcctcggctccggctcccctcagcccctacagccattggtgtgtcc accctggattccatctgtgacttgctgaccgttgctttccgtggggtgagtcactgccct ccgagtgggctctatgctcatctctgccgcatcctggctttgtgcttggggcaccgggat ccctgtgccactgcctgcctcgtcaccgagtctgtgtccatcacctgtcgccaccaactg ctcacccacctccacaggcagctcagcaaggcccagaagcaccggggatcactcgaaatg gcagaggagctacagaggctgagcctggaggagaagcctagagatgtccccctggcccgc atccagcacctcttttccttcggggcttcgggttccggtcaattccctgagcccgagaag gagagtttccaggagcgcctggcgctcatccccaggggcgtgactgtgtgtgtgttggct ctggccacgctccagcctggaactgtgggcaacaccctgctgctgacccggctggaaaaa gacaatcccccagtcactgtgcagatccccactgcccagagcaagcttcctctgagcgca gccctgaaagagttcgacgccatccagaaggaacagaaggagaacagcaactgtacagac aaacgagaatggtggactgggcggctagaactggaccacaggatggaggctctcatcact tccctggagaagcatgtgttgggctgctggaggggactgttgctaccatccagtgacgac cctggccctgcacaggaggcctcccgcctacaagagttgctgcaggaatgcggctggaaa tatcctgacccaactctgctgaaaatcatgctccatagtgccagaacccttgctcccgag gacattcagaccctggcctatgggctgtgcccagcccagccagaacgagcccaggagctt ctgagtgaggccgtaggacgtctgcagggtcagacggtaccaagcaacaggcaccttgtc ttagtgctagacaaggacctgcaaaagctgccatgggagagcatgcccagcctccgggcg ctgtccgtcactcggctgccctccttccgcttcctactcagttactccatcatcaaagag tctggggcctcgtcagtgctaagccaaggggtggatccacgcaataccttctatgtcctg aaccctcacaataacctgtccagcacagaggagcaatttcgagccaattttagcagtgaa gctggctggaaaggtgtggttggggaaaggccaagcccagaacaaatacaggcggccttg acggagcacgacttatatatctacgcagggcacggggctggggcccgcttcctggacgga caggccgtcctccggctgagctgccgggcggtggccctgctgttcggctgcagcagcgcg gccctggctgtccacgggagcctggagggagctggcattgtgctcaagtacatcatggcc ggctgtcccctgtttctgggtaatctctgggatgtgactgaccgagacattgaccgctac acggaggctctgctgcagggctggctgcgggcaggcccaggagccccgcttctgtactac gtcaaccaggcccgccaggctccccgactcaagcatcttattggggctgcacctgtggcg tacggcttgcccgtctgcctgcggtga

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