Canis lupus familiaris (dog): 610004
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Entry
610004 CDS
T01007
Symbol
JAK3
Name
(RefSeq) tyrosine-protein kinase JAK3 isoform X1
KO
K11218
Janus kinase 3 [EC:
2.7.10.2
]
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa04062
Chemokine signaling pathway
cfa04151
PI3K-Akt signaling pathway
cfa04217
Necroptosis
cfa04550
Signaling pathways regulating pluripotency of stem cells
cfa04630
JAK-STAT signaling pathway
cfa04658
Th1 and Th2 cell differentiation
cfa04659
Th17 cell differentiation
cfa05161
Hepatitis B
cfa05162
Measles
cfa05166
Human T-cell leukemia virus 1 infection
cfa05169
Epstein-Barr virus infection
cfa05200
Pathways in cancer
cfa05203
Viral carcinogenesis
cfa05223
Non-small cell lung cancer
cfa05340
Primary immunodeficiency
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
610004 (JAK3)
04151 PI3K-Akt signaling pathway
610004 (JAK3)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
610004 (JAK3)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
610004 (JAK3)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
610004 (JAK3)
04659 Th17 cell differentiation
610004 (JAK3)
04062 Chemokine signaling pathway
610004 (JAK3)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
610004 (JAK3)
05203 Viral carcinogenesis
610004 (JAK3)
09162 Cancer: specific types
05223 Non-small cell lung cancer
610004 (JAK3)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
610004 (JAK3)
05161 Hepatitis B
610004 (JAK3)
05162 Measles
610004 (JAK3)
05169 Epstein-Barr virus infection
610004 (JAK3)
09163 Immune disease
05340 Primary immunodeficiency
610004 (JAK3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
cfa01001
]
610004 (JAK3)
Enzymes [BR:
cfa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
610004 (JAK3)
Protein kinases [BR:
cfa01001
]
Non-receptor tyrosine kinases
JAK family [OT]
610004 (JAK3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
SH2_1
FERM_F1
Jak1_Phl
Kdo
ABC1
FERM_C_FAK1
Haspin_kinase
SH2
Motif
Other DBs
NCBI-GeneID:
610004
NCBI-ProteinID:
XP_005632774
Ensembl:
ENSCAFG00000015159
VGNC:
42177
UniProt:
A0A8P0NSD5
LinkDB
All DBs
Position
20:44963131..44980402
Genome browser
AA seq
1103 aa
AA seq
DB search
MAPPSEETPLIPQRSCSLSSSEAGALHVLLPPRGPGPPQRLSFSFGDHSAEELCVWAAKA
SGILPVYHSLFALATEDLSCWFPPSHIFSMEDSGTQVLVYRLRFYFPNWFGLEKCHRFGL
RKDLASAILDLPVLEHLFAQHRNDLVSGRFSVGLSLKEQDEYLSLAVLDLARMAREQAQQ
PEELLKTVSYKVCLPPDLRDLIQGLSFVTRKRIRRMVRRALRRVTACQADRHSLMAKYIM
DLERLDPARAVETFLVSFPGAAGGQDAQGLLRVAGDRGIAWSPGGQEALQPFCDFPEIVD
ISIKQAPRAGPAGEHRLVTVTKTDKQILEAEFPGLPAALSFVALVDGYFRLTSDSRHFFC
KEVAPPRLLEEVAEQCHGPITLDFAINKLKTGGSLPGSYVLRRSPQDFDSFLLTVCVQTP
LGPDYKGCLIRCDPTGTFSLAGLGRPHSSLRELLTACWDGGLHMDGAALNLTFCCTPRPK
EKSNLIVVRRGCNPPTSSPVQPQSQCQLSQMTFHKIPADSLEWHENLGHGSFTKIYRGCR
HEVVDGEARETEVLLKVMDAKHKNCMESFLEAASLMSQVSYQHLVLLHGVCMAGDSIMVQ
EFVHLGALDTYLRKSGHLVPASWKLQVIKQLAYALNYLEDKGLLHGNVSARKVLLAREGA
DGNLPFIKLSDPGVSPTVLSLEMLTDRIPWVAPECFQEARTLGLEADKWGFGATVWEVFS
GIPMPISTLDPAKKLQFYEERQQLPAPKWMELAVLIQQCMAYEPGQRPSFRAIIRDLNSL
ITSDYELLSDPTPGALAPRDGLWNGAQLYAYQDPTIFEERHLKYISQLGKGNFGSVELCR
YDPLGDNTGALVAVKQLQHSGPDQQRDFQREIQILKALHSDFIVKYRGVSYGPGRQSLRL
VMEYLPSGCLRDFLQRHRARLDAGRLLLYASQICKGMEYLGSCRCVHRDLAARNILVESE
THVKIADFGLAKLLPLDKDYYVVRGPGQNPIFWYSPESLSDNIFSCQSDVWSFGVVLYEL
FTYGNKSCSPSAEFLRIMGCERDVPALCRLVELLAEGQRLPAPPACPGEVHELMKLCWAP
SPKDRPTFSALGPQLDALWRGVA
NT seq
3312 nt
NT seq
+upstream
nt +downstream
nt
atggcacctccaagcgaggagacgcccctgatcccccagcgttcctgcagcctctcgtct
tcagaggctggtgccctgcacgtgctgctgccccctcggggccctggacccccacagcgc
ctatccttctcctttggggaccattcagctgaagagctctgtgtctgggctgctaaggcc
agtggcatcctgcctgtgtaccactccctctttgctctggccacggaggacctgtcctgc
tggttccccccaagccacatcttctccatggaggactcgggcacccaagtcctggtctac
aggctccgcttttacttccccaactggtttgggctagagaagtgccaccgcttcgggcta
cgaaaggacttggccagtgccatccttgacctgccagtcctggagcacctctttgcccag
caccgaaatgacctggtgagcggccgcttctccgtgggcctcagtctcaaggagcaagat
gaatatctcagcctggcggtgctggacctggcccggatggcccgcgagcaggctcagcag
ccggaggagctgctgaagactgtcagctacaaggtctgcctgccccccgacctgcgcgac
ctgatccagggcctgagcttcgtgacgcggaagcgcatccggaggatggtgcgccgggcc
ctgcgccgcgtgaccgcctgccaggctgaccggcactcgctcatggccaagtacatcatg
gacctggagaggctcgacccggccagggctgtcgagaccttcctcgtgagcttccccggg
gctgctggtggtcaggatgcgcaggggctgctccgagtggccggtgaccgcggcatcgcc
tggagtcccggaggacaggaggccctccagcccttctgcgactttccagaaattgtggac
atcagcatcaagcaggctccgcgtgctggcccggccggggagcaccgcctggtcaccgtc
accaagacggacaagcagatcctggaggccgagttcccggggctgcccgccgcattgtcc
ttcgtggcgctcgtcgacggatacttccggctgacctccgactccaggcacttcttctgc
aaggaggttgcgccgccgcggctgctggaggaggtggccgagcagtgccacggccccatc
acgctggattttgccatcaacaagctcaagactgggggctcacttcctggctcttacgtt
ctccgccgcagtcctcaagattttgacagcttccttctcactgtctgtgtccagaccccc
ttgggtcctgattacaagggctgcctgatccggtgtgaccccacgggaaccttctccctg
gctgggcttggccgtccccacagcagccttcgagaactcttgacagcttgctgggatggc
gggctgcacatggacggagctgcattgaacctcaccttctgctgcacccccagacccaaa
gaaaagtccaacctgattgtggtgcggaggggttgcaacccacccacatcatcccctgtt
cagccccaatcccaatgccagctcagtcagatgacatttcacaagatccctgctgacagc
ctggagtggcatgagaacctgggtcatgggtccttcaccaagatctaccggggttgtcgc
catgaggtcgtggatggggaggcccgggagacagaggtattgctcaaagtgatggatgcc
aagcacaaaaactgcatggagtcatttctggaagcagcgagtttgatgagccaagtgtca
taccagcatctcgtgttgctccatggcgtgtgcatggctggagacagtatcatggtgcag
gaatttgtacacctgggagcgctggacacatacctgcgcaagtctggccacctggtgcca
gccagctggaagctgcaggtgatcaaacagctggcatatgccctcaactacctggaagac
aaaggcctcctccatggcaatgtctcagcccggaaggtcctcctggctcgggagggggcc
gatgggaacctgcccttcatcaagctgagtgaccctggtgtcagccccactgtgctaagc
ctggagatgctcactgacaggatcccctgggtggcccctgagtgtttccaggaggcccga
acacttggcttggaagctgacaagtggggttttggtgccacagtctgggaagtgttcagc
gggatcccgatgcccatcagcaccctggatccagccaagaagctccagttttatgaggaa
cggcagcagctgcctgctccgaagtggatggagctggctgtcctgatccaacagtgcatg
gcctatgagccaggccagaggccctccttccgtgccatcatccgtgacctgaacagcctc
atcacttcagattatgagcttctctcagatcccacacctggtgccttggcaccccgcgat
gggctgtggaacggtgcccagctctatgcctaccaggaccctaccatttttgaggagaga
cacctcaagtacatctcacagctgggcaagggcaactttgggagcgtggaactgtgccgc
tatgacccactgggtgacaacacgggcgccctagtggctgtgaagcagctgcagcacagc
gggccagaccagcagagggacttccagagggagatccagatcctcaaagccctccacagc
gacttcattgtcaagtaccgcggagtcagctatggcccaggccgccagagcctgcggctg
gtgatggagtacctgcccagcggctgcctgcgcgacttcctgcagcggcaccgcgcgcgc
ctcgacgccggccgcctgctcctctacgcctcgcagatctgcaagggcatggagtacctg
ggctcctgccgctgcgtgcaccgcgacctggcagcccgcaacatcctggtggagagcgag
acgcacgtcaagatcgccgactttggcctcgccaagctgctgcccctcgacaaagactac
tacgtggtccgcgggcccggccagaaccccatcttctggtactccccagagtccctctct
gacaacatcttctcgtgccagtcggacgtctggagcttcggggttgtcctgtacgagctt
ttcacctatggcaacaagagttgcagcccctcagccgagttcctgaggataatgggatgt
gagcgagatgtcccggccctctgccgcctggtggagctgctggctgagggccagaggctg
cctgcgcctcctgcctgccctggtgaggttcacgagctcatgaagctgtgctgggccccc
agcccgaaagaccggccaacattcagtgccctgggcccccagctggatgcactctggcgt
ggagtagcatag
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integrated database retrieval system
