Camelus ferus (Wild Bactrian camel): 102503866 Help Entry 102503866         CDS       T02979                                  Symbol JAK3 Name (RefSeq) tyrosine-protein kinase JAK3   KO K11218   Janus kinase 3 [EC:2.7.10.2] Organism cfr  Camelus ferus (Wild Bactrian camel) Pathway cfr04062   Chemokine signaling pathway cfr04151   PI3K-Akt signaling pathway cfr04217   Necroptosis cfr04550   Signaling pathways regulating pluripotency of stem cells cfr04630   JAK-STAT signaling pathway cfr04658   Th1 and Th2 cell differentiation cfr04659   Th17 cell differentiation cfr05161   Hepatitis B cfr05162   Measles cfr05166   Human T-cell leukemia virus 1 infection cfr05169   Epstein-Barr virus infection cfr05200   Pathways in cancer cfr05203   Viral carcinogenesis cfr05223   Non-small cell lung cancer cfr05340   Primary immunodeficiency Brite KEGG Orthology (KO) [BR:cfr00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     102503866 (JAK3)    04151 PI3K-Akt signaling pathway     102503866 (JAK3)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     102503866 (JAK3)   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     102503866 (JAK3)  09150 Organismal Systems   09151 Immune system    04658 Th1 and Th2 cell differentiation     102503866 (JAK3)    04659 Th17 cell differentiation     102503866 (JAK3)    04062 Chemokine signaling pathway     102503866 (JAK3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102503866 (JAK3)    05203 Viral carcinogenesis     102503866 (JAK3)   09162 Cancer: specific types    05223 Non-small cell lung cancer     102503866 (JAK3)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     102503866 (JAK3)    05161 Hepatitis B     102503866 (JAK3)    05162 Measles     102503866 (JAK3)    05169 Epstein-Barr virus infection     102503866 (JAK3)   09163 Immune disease    05340 Primary immunodeficiency     102503866 (JAK3)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:cfr01001]     102503866 (JAK3) Enzymes [BR:cfr01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      102503866 (JAK3) Protein kinases [BR:cfr01001]  Non-receptor tyrosine kinases   JAK family [OT]    102503866 (JAK3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase FERM_F2 SH2_1 FERM_F1 Jak1_Phl Kdo ABC1 FERM_C_FAK1 Haspin_kinase Motif Other DBs NCBI-GeneID:  102503866 NCBI-ProteinID:  XP_006174867 UniProt:  A0A8B6Y7E6 LinkDB All DBs Position 22:16504476..16520061 Genome browser AA seq 1104 aa AA seqDB search MAPPSEEMPLIPQRSCSLSSSEAGALHVLLPPRGPGPPQRLSFSFGDHSAEELCVRAAKA SGILPVYHSLFALATEDLSCWFPPSHIFSVEDVGTQVLVYRLRFYFPNWFGLEKCHRFGL RKDLACAILDLPVLEHLFAQHRNDLVSGCLPVGLSLKEQGECLSLAVLDLARMALEQAQR PEELLKTISYKVCLPPGLRDLIQGLSFVTRKRIRRTVRRALRRVAACQADRHSLMAKYIM DLERLDPGRAAETFRVGLPGTAGGQDAPGLLRVAGGSGIAWSPGEQEVLQPFCDFPEIVD ISIKQAPRFGPAGEHRLVTVTRTDNQILEAEFPGLPAALSFVALVDGYFRLTTDSQHFFC KEVAPPRLLEEVAEQCYGPITLDFAINKLKTGGSLPGSYVLRRSPQDFDSFLLTICVQTP LGPDYKGCLIRCDPSGTFSLAGLGRPHSSLRELLAACWDSGLHVDGIELNLTFCCTPRPK EKSNLIVVRRGCSLPTSCPVQPQSQCQLSQMTFHKIPADSLEWHENLGHGSFTKIYRGCR HETVDGEARETEVLLKVMDVKHKNCMESFLEAASLMSQVSYQHLVLLHGVCMAGDSIMVQ EFVHLGALDTYLRKSGHLVPASWKLQVIKQLAYALNYLEDKGLPHGNVSARKVLLAREGA DGNPPFIKLSDPGVSPTVLSLEMLTDRIPWVAPECLQEARTLGLEADKWGFGATVWEVFS GVMMPISTLDPAKKLQFYEERQQLPAPKWMELALLIQQCMAYEPGQRPSFRAVIRDLNSL ITSDYELLSDPTPGALAPRDGLWNGAQLYACQDPTIFEERHLKYISQLGKGNFGSVELCR YDPLGDNTGALVAVKQLQHSGPEQQKDFQREIQILKALHSDFIVKYRGVSYGPGRQSLRL VMEYLPSGCLRDFLQRHRARLDAGRLLLFASQICKGMEYLGSRRCVHRDLAARNILVENE THVKIADFGLAKLLPLDKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSFGVVLYEL FTYSDKSCSPSAEFLRMMGCERDVPALCRLLELLAEGQRLPAPPACPGEVHELMKLCWAP SPQDRPPFSALGPQLDALWSGSQG NT seq 3315 nt NT seq  +upstreamnt  +downstreamnt atggcacctccaagtgaggagatgcccttgatccctcagcgttcctgcagcctctcctct tcagaggctggcgccctgcacgtgctgctgccccctcggggccctggacccccacagcgc ctatccttctcttttggggaccactcagctgaagagctgtgtgttcgagctgctaaggcc agtggtatcctgcccgtgtaccactccctctttgctctggccacggaggacctatcctgt tggttccccccgagccacatcttctccgtggaagacgtgggcacccaggtccttgtctac aggctccgcttttacttccccaactggtttgggctagaaaagtgccaccgctttgggcta cgaaaggacttagcctgcgccatccttgacctgccagtcctggagcacctatttgctcag caccgaaatgacctggtgagcggctgcctcccagtgggcctcagcctcaaggagcagggt gagtgtctcagcttggctgtgctggacctggcccgcatggctctcgagcaggctcagcgg cccgaggagctgctgaagaccatcagctacaaggtctgcctgccccccggcctgcgcgac ctgatccagggcctgagtttcgtgacacgaaagcgtatccgaaggacagtgcgcagggct ttgcgccgcgtggccgcctgccaggctgacaggcattcactcatggccaagtacatcatg gatctcgaacggctggacccaggcagggccgccgagaccttccgcgtgggcctccccggg acggctggtggtcaggatgcgccagggctgctccgcgtggctggtggcagcggcatagcc tggagcccaggagaacaagaggtccttcagcccttctgcgactttccagaaattgtggat atcagcatcaagcaggccccgcgctttggcccggctggggagcaccgcctggtcaccgtc accaggacggacaaccagatcctggaggccgagttcccggggctgcccgccgccttgtcc ttcgtggcactcgtggatggctacttcaggctgaccaccgactcccagcacttcttctgc aaggaggtggcgccgccgcggctgctggaggaggtggctgagcagtgctatggccccatc accctggattttgccatcaacaaactcaagactgggggctcgcttcccggctcctacgtt ctccgtcgcagcccccaggattttgacagcttcctcctaactatctgtgtccagaccccc ctgggccctgattacaaaggctgcctcattcggtgtgacccttcgggaactttctccctg gctggccttggccgtccccacagcagtcttcgagagctcctggcagcctgttgggatagt gggttgcatgtggatgggattgagctgaacctcaccttctgctgcacccccagacccaaa gaaaaatccaacctgatagtggtccggagaggttgcagcctgcccacgtcatgccctgtt cagccccaatctcagtgccagctgagtcagatgacgtttcacaagatccctgctgacagc ctggagtggcatgagaatcttggtcacgggtctttcaccaagatttaccgcggctgtcga catgagaccgtggatggggaggcccgggagacagaggtgctgctcaaagtgatggatgtc aagcacaagaactgcatggagtcattcctggaagcagcgagcttgatgagccaagtgtca taccagcatcttgtgttgctccatggcgtgtgcatggctggagacagcatcatggtgcag gagtttgtacacctgggagcactggacacgtatctgcgcaagagtggccacctggtgcct gccagctggaagctacaggtgatcaaacagctggcctatgccctcaactatctggaagac aaaggtctccctcatggcaatgtctcagcccggaaagtgctcctggcccgggagggggct gatgggaacccacccttcatcaaactgagtgaccctggtgtcagccccactgtgctaagt ctggagatgctcactgacaggattccctgggtggcccctgagtgtctccaggaggcccga acacttggcttggaagctgacaagtggggctttggtgccacagtctgggaggtgttcagc ggtgtcatgatgcccatcagcaccctggatccagccaagaagctccagttttacgaggaa cgtcagcagctgcccgcccccaagtggatggagctggccctgctgatccaacagtgcatg gcgtacgagccgggccagaggccctccttccgtgctgtcatccgtgacctgaacagcctc atcacttcagattatgagctcctctcagaccccacacctggtgccttggcaccccgtgac gggctttggaatggtgcccagctctatgcctgccaggaccctaccatctttgaggagaga cacctcaagtatatctcacagctgggcaagggcaactttggcagcgtggaactatgccgc tatgacccactgggcgacaacacaggcgccctggtggctgtgaagcagctgcagcacagt gggccagaacagcagaaggacttccagcgggagatccagatcctcaaagccctgcacagc gacttcattgtcaagtaccgaggtgtcagctatggtccaggccgccagagcctgcggctg gtcatggagtacctgcccagcggctgtctgcgcgacttcctgcagcggcaccgtgcccgc ctcgacgctggccgcctgctcctctttgcctcgcagatctgcaagggcatggagtacctg ggctcccgccgctgcgtgcaccgcgacctggcagcccgtaacatcctggtggagaacgag acgcacgtcaagatcgcagacttcggcctcgccaagcttctgccgctcgacaaagactac tacgtggtccgcgagcccggccaaagtcccatcttctggtatgccccagagtccctctca gataacatcttctcgcgccagtcggatgtctggagcttcggggtcgtcctgtatgagctc ttcacctacagtgacaagagctgtagcccctcagctgagttcctgcggatgatgggatgt gagcgagatgtcccagccctctgccgcctcctggagctgctggctgagggccagaggctg cccgcacctcctgcctgccctggtgaggttcatgagctcatgaagctatgctgggcccct agcccacaagaccggccaccattcagtgctctgggtccccagctggatgcactgtggagt ggaagccagggatag

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