KEGG   Camelus ferus (Wild Bactrian camel): 102520923
Entry
102520923         CDS       T02979                                 
Symbol
PIK3R1
Name
(RefSeq) phosphatidylinositol 3-kinase regulatory subunit alpha isoform X2
  KO
K02649  phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
Organism
cfr  Camelus ferus (Wild Bactrian camel)
Pathway
cfr01521  EGFR tyrosine kinase inhibitor resistance
cfr01522  Endocrine resistance
cfr01524  Platinum drug resistance
cfr04012  ErbB signaling pathway
cfr04014  Ras signaling pathway
cfr04015  Rap1 signaling pathway
cfr04024  cAMP signaling pathway
cfr04062  Chemokine signaling pathway
cfr04066  HIF-1 signaling pathway
cfr04068  FoxO signaling pathway
cfr04070  Phosphatidylinositol signaling system
cfr04071  Sphingolipid signaling pathway
cfr04072  Phospholipase D signaling pathway
cfr04081  Hormone signaling
cfr04140  Autophagy - animal
cfr04150  mTOR signaling pathway
cfr04151  PI3K-Akt signaling pathway
cfr04152  AMPK signaling pathway
cfr04210  Apoptosis
cfr04211  Longevity regulating pathway
cfr04213  Longevity regulating pathway - multiple species
cfr04218  Cellular senescence
cfr04360  Axon guidance
cfr04370  VEGF signaling pathway
cfr04380  Osteoclast differentiation
cfr04510  Focal adhesion
cfr04550  Signaling pathways regulating pluripotency of stem cells
cfr04611  Platelet activation
cfr04613  Neutrophil extracellular trap formation
cfr04620  Toll-like receptor signaling pathway
cfr04625  C-type lectin receptor signaling pathway
cfr04630  JAK-STAT signaling pathway
cfr04650  Natural killer cell mediated cytotoxicity
cfr04660  T cell receptor signaling pathway
cfr04662  B cell receptor signaling pathway
cfr04664  Fc epsilon RI signaling pathway
cfr04666  Fc gamma R-mediated phagocytosis
cfr04668  TNF signaling pathway
cfr04670  Leukocyte transendothelial migration
cfr04722  Neurotrophin signaling pathway
cfr04725  Cholinergic synapse
cfr04750  Inflammatory mediator regulation of TRP channels
cfr04810  Regulation of actin cytoskeleton
cfr04910  Insulin signaling pathway
cfr04914  Progesterone-mediated oocyte maturation
cfr04915  Estrogen signaling pathway
cfr04917  Prolactin signaling pathway
cfr04919  Thyroid hormone signaling pathway
cfr04923  Regulation of lipolysis in adipocytes
cfr04926  Relaxin signaling pathway
cfr04929  GnRH secretion
cfr04930  Type II diabetes mellitus
cfr04931  Insulin resistance
cfr04932  Non-alcoholic fatty liver disease
cfr04933  AGE-RAGE signaling pathway in diabetic complications
cfr04935  Growth hormone synthesis, secretion and action
cfr04960  Aldosterone-regulated sodium reabsorption
cfr04973  Carbohydrate digestion and absorption
cfr05010  Alzheimer disease
cfr05017  Spinocerebellar ataxia
cfr05020  Prion disease
cfr05100  Bacterial invasion of epithelial cells
cfr05135  Yersinia infection
cfr05142  Chagas disease
cfr05146  Amoebiasis
cfr05160  Hepatitis C
cfr05161  Hepatitis B
cfr05162  Measles
cfr05163  Human cytomegalovirus infection
cfr05164  Influenza A
cfr05165  Human papillomavirus infection
cfr05166  Human T-cell leukemia virus 1 infection
cfr05167  Kaposi sarcoma-associated herpesvirus infection
cfr05168  Herpes simplex virus 1 infection
cfr05169  Epstein-Barr virus infection
cfr05170  Human immunodeficiency virus 1 infection
cfr05171  Coronavirus disease - COVID-19
cfr05200  Pathways in cancer
cfr05203  Viral carcinogenesis
cfr05205  Proteoglycans in cancer
cfr05206  MicroRNAs in cancer
cfr05207  Chemical carcinogenesis - receptor activation
cfr05208  Chemical carcinogenesis - reactive oxygen species
cfr05210  Colorectal cancer
cfr05211  Renal cell carcinoma
cfr05212  Pancreatic cancer
cfr05213  Endometrial cancer
cfr05214  Glioma
cfr05215  Prostate cancer
cfr05218  Melanoma
cfr05220  Chronic myeloid leukemia
cfr05221  Acute myeloid leukemia
cfr05222  Small cell lung cancer
cfr05223  Non-small cell lung cancer
cfr05224  Breast cancer
cfr05225  Hepatocellular carcinoma
cfr05226  Gastric cancer
cfr05230  Central carbon metabolism in cancer
cfr05231  Choline metabolism in cancer
cfr05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
cfr05415  Diabetic cardiomyopathy
cfr05417  Lipid and atherosclerosis
cfr05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:cfr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    102520923 (PIK3R1)
   04014 Ras signaling pathway
    102520923 (PIK3R1)
   04015 Rap1 signaling pathway
    102520923 (PIK3R1)
   04370 VEGF signaling pathway
    102520923 (PIK3R1)
   04630 JAK-STAT signaling pathway
    102520923 (PIK3R1)
   04668 TNF signaling pathway
    102520923 (PIK3R1)
   04066 HIF-1 signaling pathway
    102520923 (PIK3R1)
   04068 FoxO signaling pathway
    102520923 (PIK3R1)
   04070 Phosphatidylinositol signaling system
    102520923 (PIK3R1)
   04072 Phospholipase D signaling pathway
    102520923 (PIK3R1)
   04071 Sphingolipid signaling pathway
    102520923 (PIK3R1)
   04024 cAMP signaling pathway
    102520923 (PIK3R1)
   04151 PI3K-Akt signaling pathway
    102520923 (PIK3R1)
   04152 AMPK signaling pathway
    102520923 (PIK3R1)
   04150 mTOR signaling pathway
    102520923 (PIK3R1)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    102520923 (PIK3R1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    102520923 (PIK3R1)
  09143 Cell growth and death
   04210 Apoptosis
    102520923 (PIK3R1)
   04218 Cellular senescence
    102520923 (PIK3R1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    102520923 (PIK3R1)
   04550 Signaling pathways regulating pluripotency of stem cells
    102520923 (PIK3R1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    102520923 (PIK3R1)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    102520923 (PIK3R1)
   04613 Neutrophil extracellular trap formation
    102520923 (PIK3R1)
   04620 Toll-like receptor signaling pathway
    102520923 (PIK3R1)
   04625 C-type lectin receptor signaling pathway
    102520923 (PIK3R1)
   04650 Natural killer cell mediated cytotoxicity
    102520923 (PIK3R1)
   04660 T cell receptor signaling pathway
    102520923 (PIK3R1)
   04662 B cell receptor signaling pathway
    102520923 (PIK3R1)
   04664 Fc epsilon RI signaling pathway
    102520923 (PIK3R1)
   04666 Fc gamma R-mediated phagocytosis
    102520923 (PIK3R1)
   04670 Leukocyte transendothelial migration
    102520923 (PIK3R1)
   04062 Chemokine signaling pathway
    102520923 (PIK3R1)
  09152 Endocrine system
   04910 Insulin signaling pathway
    102520923 (PIK3R1)
   04923 Regulation of lipolysis in adipocytes
    102520923 (PIK3R1)
   04929 GnRH secretion
    102520923 (PIK3R1)
   04915 Estrogen signaling pathway
    102520923 (PIK3R1)
   04914 Progesterone-mediated oocyte maturation
    102520923 (PIK3R1)
   04917 Prolactin signaling pathway
    102520923 (PIK3R1)
   04926 Relaxin signaling pathway
    102520923 (PIK3R1)
   04935 Growth hormone synthesis, secretion and action
    102520923 (PIK3R1)
   04919 Thyroid hormone signaling pathway
    102520923 (PIK3R1)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    102520923 (PIK3R1)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    102520923 (PIK3R1)
  09156 Nervous system
   04725 Cholinergic synapse
    102520923 (PIK3R1)
   04722 Neurotrophin signaling pathway
    102520923 (PIK3R1)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    102520923 (PIK3R1)
  09158 Development and regeneration
   04360 Axon guidance
    102520923 (PIK3R1)
   04380 Osteoclast differentiation
    102520923 (PIK3R1)
  09149 Aging
   04211 Longevity regulating pathway
    102520923 (PIK3R1)
   04213 Longevity regulating pathway - multiple species
    102520923 (PIK3R1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102520923 (PIK3R1)
   05206 MicroRNAs in cancer
    102520923 (PIK3R1)
   05205 Proteoglycans in cancer
    102520923 (PIK3R1)
   05207 Chemical carcinogenesis - receptor activation
    102520923 (PIK3R1)
   05208 Chemical carcinogenesis - reactive oxygen species
    102520923 (PIK3R1)
   05203 Viral carcinogenesis
    102520923 (PIK3R1)
   05230 Central carbon metabolism in cancer
    102520923 (PIK3R1)
   05231 Choline metabolism in cancer
    102520923 (PIK3R1)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    102520923 (PIK3R1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    102520923 (PIK3R1)
   05212 Pancreatic cancer
    102520923 (PIK3R1)
   05225 Hepatocellular carcinoma
    102520923 (PIK3R1)
   05226 Gastric cancer
    102520923 (PIK3R1)
   05214 Glioma
    102520923 (PIK3R1)
   05221 Acute myeloid leukemia
    102520923 (PIK3R1)
   05220 Chronic myeloid leukemia
    102520923 (PIK3R1)
   05218 Melanoma
    102520923 (PIK3R1)
   05211 Renal cell carcinoma
    102520923 (PIK3R1)
   05215 Prostate cancer
    102520923 (PIK3R1)
   05213 Endometrial cancer
    102520923 (PIK3R1)
   05224 Breast cancer
    102520923 (PIK3R1)
   05222 Small cell lung cancer
    102520923 (PIK3R1)
   05223 Non-small cell lung cancer
    102520923 (PIK3R1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    102520923 (PIK3R1)
   05170 Human immunodeficiency virus 1 infection
    102520923 (PIK3R1)
   05161 Hepatitis B
    102520923 (PIK3R1)
   05160 Hepatitis C
    102520923 (PIK3R1)
   05171 Coronavirus disease - COVID-19
    102520923 (PIK3R1)
   05164 Influenza A
    102520923 (PIK3R1)
   05162 Measles
    102520923 (PIK3R1)
   05168 Herpes simplex virus 1 infection
    102520923 (PIK3R1)
   05163 Human cytomegalovirus infection
    102520923 (PIK3R1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    102520923 (PIK3R1)
   05169 Epstein-Barr virus infection
    102520923 (PIK3R1)
   05165 Human papillomavirus infection
    102520923 (PIK3R1)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    102520923 (PIK3R1)
   05100 Bacterial invasion of epithelial cells
    102520923 (PIK3R1)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    102520923 (PIK3R1)
   05142 Chagas disease
    102520923 (PIK3R1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    102520923 (PIK3R1)
   05017 Spinocerebellar ataxia
    102520923 (PIK3R1)
   05020 Prion disease
    102520923 (PIK3R1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    102520923 (PIK3R1)
   05418 Fluid shear stress and atherosclerosis
    102520923 (PIK3R1)
   05415 Diabetic cardiomyopathy
    102520923 (PIK3R1)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    102520923 (PIK3R1)
   04932 Non-alcoholic fatty liver disease
    102520923 (PIK3R1)
   04931 Insulin resistance
    102520923 (PIK3R1)
   04933 AGE-RAGE signaling pathway in diabetic complications
    102520923 (PIK3R1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    102520923 (PIK3R1)
   01524 Platinum drug resistance
    102520923 (PIK3R1)
   01522 Endocrine resistance
    102520923 (PIK3R1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:cfr04131]
    102520923 (PIK3R1)
Membrane trafficking [BR:cfr04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    102520923 (PIK3R1)
SSDB
Motif
Pfam: PI3K_P85_iSH2 SH2 SH2_1 AAA_13 CCDC113_CCDC96_CC Laminin_I PI_PP_I Syntaxin Transcrip_act
Other DBs
NCBI-GeneID: 102520923
NCBI-ProteinID: XP_006185241
UniProt: A0A8B6YFU2
LinkDB
Position
3:45623851..45706845
AA seq 454 aa
MYNTVWNMEELDLDYAKTDINCGTDLMFYIEMDPPALPPKPPKPTTVANNGMNNNMSLQD
AEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKY
GFSDPLTFNSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKLH
EYNTQFQEKSREYDRLYEDYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIE
KFKREGNEKEIQRIMHNYEKLKSRISEIVDSRRRLEEDLKKQAAEYREIDKRMNSIKPDL
IQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSSN
RNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYGS
LKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR
NT seq 1365 nt   +upstreamnt  +downstreamnt
atgtacaacactgtttggaatatggaagagctggatttagactatgctaagacagatata
aattgtggcacagacttgatgttttatatagaaatggatccaccagcactgcctcctaaa
ccaccaaaacccactactgtagccaacaacggtatgaataacaatatgtccttacaagat
gctgaatggtactggggcgatatctcgagggaagaagtgaatgaaaaacttcgagataca
gccgacgggacctttttggtacgagatgcgtctactaaaatgcatggtgattatactctt
acactaaggaaaggaggaaataacaaattaatcaaaatatttcaccgagatgggaaatat
ggcttctctgacccattaaccttcaattctgtggttgaactaataaaccactaccggaat
gaatctctagctcagtataatcccaaactggatgtgaaattactgtatccagtgtccaaa
taccaacaggatcaagttgtcaaagaagataatattgaagctgtagggaaaaaattacat
gaatataacactcaatttcaagaaaagagtcgggaatatgatagattatatgaagattat
acccgtacttcccaggaaatccaaatgaaaagaacagctattgaagcatttaatgaaact
ataaaaatatttgaagaacagtgccaaactcaggagcggtacagcaaagaatacatagag
aagtttaaacgtgaaggcaatgagaaagaaatacaaaggattatgcataattatgaaaaa
ttaaagtctcgaatcagtgaaattgtcgacagcaggcgaaggctggaggaggacttgaag
aagcaggcggccgagtaccgcgagattgacaagcgcatgaacagcattaaacccgacctt
attcagctgagaaagaccagagaccaatacttgatgtggttgactcagaaaggtgttcgg
cagaagaagctgaatgagtggctgggcaatgagaacactgaagaccaatattcgctggtg
gaagatgacgaggacttgccccaccacgatgagaagacctggaacgtgggaagcagcaac
cgaaacaaagccgaaaacctactgcgggggaaacgagacggaacttttctggtccgggaa
agcagtaaacagggctgctacgcctgctctgtggtggtggacggcgaggtcaagcactgc
gtcatcaacaagacggccacgggctacggcttcgcggagccctacaacctgtacggctcc
ctcaaggagctggtgctccactaccagcacacgtccctcgtgcagcacaacgactccctc
aacgtcacactggcctacccggtgtacgcgcaacagcggcgatga

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