Camelus ferus (Wild Bactrian camel): 102522017 Help Entry 102522017         CDS       T02979                                  Symbol INSR Name (RefSeq) insulin receptor isoform X1   KO K04527   insulin receptor [EC:2.7.10.1] Organism cfr  Camelus ferus (Wild Bactrian camel) Pathway cfr04010   MAPK signaling pathway cfr04014   Ras signaling pathway cfr04015   Rap1 signaling pathway cfr04022   cGMP-PKG signaling pathway cfr04066   HIF-1 signaling pathway cfr04068   FoxO signaling pathway cfr04072   Phospholipase D signaling pathway cfr04081   Hormone signaling cfr04150   mTOR signaling pathway cfr04151   PI3K-Akt signaling pathway cfr04152   AMPK signaling pathway cfr04211   Longevity regulating pathway cfr04213   Longevity regulating pathway - multiple species cfr04520   Adherens junction cfr04910   Insulin signaling pathway cfr04913   Ovarian steroidogenesis cfr04923   Regulation of lipolysis in adipocytes cfr04930   Type II diabetes mellitus cfr04931   Insulin resistance cfr04932   Non-alcoholic fatty liver disease cfr04960   Aldosterone-regulated sodium reabsorption cfr05010   Alzheimer disease cfr05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:cfr00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     102522017 (INSR)    04014 Ras signaling pathway     102522017 (INSR)    04015 Rap1 signaling pathway     102522017 (INSR)    04066 HIF-1 signaling pathway     102522017 (INSR)    04068 FoxO signaling pathway     102522017 (INSR)    04072 Phospholipase D signaling pathway     102522017 (INSR)    04022 cGMP-PKG signaling pathway     102522017 (INSR)    04151 PI3K-Akt signaling pathway     102522017 (INSR)    04152 AMPK signaling pathway     102522017 (INSR)    04150 mTOR signaling pathway     102522017 (INSR)   09133 Signaling molecules and interaction    04081 Hormone signaling     102522017 (INSR)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04520 Adherens junction     102522017 (INSR)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     102522017 (INSR)    04923 Regulation of lipolysis in adipocytes     102522017 (INSR)    04913 Ovarian steroidogenesis     102522017 (INSR)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     102522017 (INSR)   09149 Aging    04211 Longevity regulating pathway     102522017 (INSR)    04213 Longevity regulating pathway - multiple species     102522017 (INSR)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     102522017 (INSR)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     102522017 (INSR)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     102522017 (INSR)    04932 Non-alcoholic fatty liver disease     102522017 (INSR)    04931 Insulin resistance     102522017 (INSR)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:cfr01001]     102522017 (INSR)   09183 Protein families: signaling and cellular processes    04090 CD molecules [BR:cfr04090]     102522017 (INSR) Enzymes [BR:cfr01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.1  receptor protein-tyrosine kinase      102522017 (INSR) Protein kinases [BR:cfr01001]  Receptor tyrosine kinases (RTK)   INSR family [OT]    102522017 (INSR) CD molecules [BR:cfr04090]  Proteins   102522017 (INSR) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Recep_L_domain Pkinase Furin-like Insulin_TMD fn3 Ig_DSCAM-DSCAML_C Kinase-like B2 DUF4476 Motif Other DBs NCBI-GeneID:  102522017 NCBI-ProteinID:  XP_032322128 UniProt:  A0A8B8RVZ4 LinkDB All DBs Position 22:22545513..22660003 Genome browser AA seq 1382 aa AA seqDB search MGAGGGRGAAAVPLLVAVAALLVGAAGHLYPGEVCPGMDIRNNLTRLHELANCSVIEGHL QILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYAL VIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNE ECGDICPGTAKGKTNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHSECL GNCSEPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHNKCKNSRRQG CHQYVIHNNKCIPECPSGYTMNSSNLMCTPCLGPCPKVCHLLEGEKTIDSVTSAQELRGC TIVNGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETL EIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQE RNDIALKTNGDQASCENELLKFSYIRTSHDKILLKWEPYWPPDFRDLLGFMLFYKEAPYQ NVTEFDGQDACGSNSWTVVDIDPPMRSNDPKSQNHPGWLMRGLKPWTQYAIFVKTLVTFS DERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVFWE RQAEDSELYELDYCLKGLKLPSRTWSPPFESEGSQKHNQTEYEEAAGECCSCPKTDSQIL KELEESSFRKTFEDYLHNVVFIPRKSSSGPGAEDTRPSRRRRALADIGNGTAAVPTLPGF PNASSTSAPTSSEEHRPFEKVVSKESLVISGLRHFTGYRIELQACNQDAPEERCSVAAYV SARTMPEAKADDIVGPVTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHLCV SRRHFALERGCRLRGLPPGNYSVRVRATSLAGNGSWTEATYFYVTDYLDVPSNIAKIIIG PLIFVFLFSVVIGSIYLFLRKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVPDEWEVPR EKIALLRELGQGSFGMVYEGNARDIVKGEAETRVAVKTVNESASLRERIEFLNEASVMKG FTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMA AEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPV RWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQPDN CPDRVTNLMRMCWQFNPKMRPTFLEIVDLLKDDLHPSFPEVSFFHSEENKAPESEELDME FEDMESVPLDRSAHSQREEAGGRDAGSALGLKRGYEEHIPYTHMNGGKRNGRILTLPRSD PS NT seq 4149 nt NT seq  +upstreamnt  +downstreamnt atgggcgccgggggcgggcggggggcggcggccgtgccgctgctggtggccgttgccgcg ctgctggtgggcgccgcgggccacctgtaccctggagaggtgtgccccggcatggacatc cggaacaacctcacccggctgcacgagctggccaactgctccgtcatcgaaggacatctg cagatactgctgatgttcaaaacgaggcctgaggatttccgagacctcagtttccccaaa ctcatcatgatcaccgattacttgctgctcttccgggtctacgggctggagagcctgaag gacctgttccccaacctcacggtcatccggggctcccgcctcttcttcaactatgcgctg gtcatcttcgagatggttcatctgaaggagcttggcctctacaatttgatgaacattacg cggggctcggtccgcatcgagaagaacaatgagctctgctacctggccaccatcgactgg tcgcgcatcctggactccgtggaggataattacatcgtgctgaacaaagatgacaacgag gaatgtggggacatttgtccaggcactgccaagggcaaaaccaactgccctgccactgtc atcaatgggcaatttgtcgagcggtgttggacgcacagccactgtcagaaagtttgtccg accatctgcaagtcgcacggctgcaccgcggagggcctctgctgccacagcgagtgcttg ggtaactgctccgagcccgacgaccccaccaagtgcgtggcctgccgcaacttctacctg gacggccgctgcgtggagacctgcccgcccccctactaccacttccaagactggcgctgc gtgaacttcagcttctgccaggatctgcacaacaaatgcaagaactctcggaggcagggc tgccaccagtacgtcattcacaataacaagtgcatccccgagtgtccctctgggtacacg atgaattccagcaacttgatgtgcactccatgcctgggcccctgtcccaaggtctgccac ctcctggaaggcgagaagaccatcgactcagtgacgtccgcccaggagctccgaggctgc accattgtcaacgggagcttaatcatcaacattcgagggggcaacaatctggcagctgag ctggaggccaaccttggactcattgaagaaatttcagggtacctgaaaatccgccggtcc tacgccctcgtgtcactttccttcttccggaagttacgtctgattcgaggagagaccttg gagattgggaactactccttctacgccttggacaaccagaacctaaggcagctgtgggac tggagcaaacacaacctcaccatcacgcaggggaaactgttcttccactataaccccaag ctctgcttgtcagaaattcacaagatggaggaagtttcaggaaccaaggggcgccaggag agaaacgacattgccctgaagaccaatggggaccaggcgtcctgtgaaaatgaattactt aaattctcttacattcggacatctcatgacaagatcttgctgaaatgggagccctattgg ccccctgacttccgagatctcttggggttcatgcttttctacaaagaggccccttatcag aacgtgacagagttcgatggacaggatgcgtgcggctccaacagctggacggtggtggac attgacccgccgatgaggtccaatgaccccaagtcacagaaccaccccgggtggctgatg cggggtctcaagccctggacccagtacgccatctttgtcaagaccttggtcaccttttct gacgaacgccgcacgtacggggccaagagcgacatcatctatgtccagacagatgccact aatccttccgtcccactggatcccatctcggtttctaattcctcatcccagattattctg aagtggaagcctccctctgaccccaacggcaacatcacacactacctggttttctgggag aggcaggcggaagacagcgagctgtatgaattggattattgcctcaaagggctgaagctg ccgtcccggacctggtctccgccgtttgagtctgagggctcccagaagcacaatcagacc gagtacgaggaggctgccggagagtgctgctcctgcccgaagaccgactctcagatcctg aaggagctggaggaatcctcgttccggaagacatttgaggattacctgcacaatgtggtt ttcatccccagaaaatcctcttcaggccctggcgcggaggacaccaggccgtcgcggaga cgcagggccctggctgacatagggaatggcacagcggccgtgcccacgctcccggggttc cccaacgcctcctccaccagcgcacccaccagctcggaggagcacagacccttcgagaaa gtggtgagcaaagagtcactggtcatctcggggctgcgtcactttaccggctaccgcatc gagctgcaggcttgcaaccaagatgcccccgaggagcggtgcagcgtggccgcctacgtc agcgccaggaccatgcccgaagccaaggccgatgatattgtgggccccgtgacccacgaa atcttcgagaacaacgtcgtccacctgatgtggcaggagcccaaggaacccaacggtctg atcgtgctctatgaagtgagctaccgacgatacggcgatgaggagctgcacctgtgcgtc tctcgaaggcatttcgctctggagcggggctgcaggctgcgcgggctgccgcccgggaat tacagcgtgagagttcgggccacctccctggcgggcaacggctcctggacagaagccact tatttctatgtgacagattatttagacgtcccatcaaatattgcaaagattatcatcggc cccctcatctttgtatttctcttcagtgttgtgattgggagtatttatctgttcctgaga aagaggcagccggatgggccactgggaccactgtatgcttcttcgaaccccgagtacctc agtgccagcgatgtgttcccgtgttctgtgtacgtgccggacgagtgggaggtgccccgg gagaagatcgcgctgctgcgagagctcgggcagggctccttcggcatggtgtacgagggc aacgccagggacatcgtcaagggcgaggcggagacccgcgtggcggtgaagacggtcaac gagtcggccagcctgcgagaacggattgagtttctcaacgaggcctcggtcatgaagggc ttcacctgccaccacgtggtccgcctcctgggggtggtgtccaaaggccagccgacactg gtggtgatggagttgatggctcacggagacttaaagagctacctccgttccctgcggccg gaggccgagaataaccctggtcgccctccccctacgctgcaagagatgattcagatggcg gcggagattgccgatgggatggcgtacctgaacgccaagaagttcgtgcaccgggacctc gcagctcggaactgcatggtcgctcatgattttaccgtcaaaatcggagactttggaatg accagagacatctacgaaacggactactaccggaaagggggcaagggcctgctccccgtg cggtggatggcacccgaatccctgaaggacggggtcttcaccacttcttccgacatgtgg tccttcggcgtggtcctctgggaaattaccagcttggcagaacagccttaccaaggccta tctaatgagcaggtgttgaaattcgtcatggatggagggtatctggatcaacctgacaac tgtccagacagagtcaccaacctgatgcgcatgtgctggcagttcaaccccaagatgcgg ccgaccttcctggagatcgtcgacctgctcaaggacgacctgcaccccagctttcccgaa gtttccttcttccacagcgaggagaacaaggcgccggagagcgaggagctggacatggag tttgaggacatggagagcgtcccgctggaccggtcggcacactcgcagcgggaggaggcc gggggccgggacgcggggtcggcgctggggctgaagcggggctacgaggagcacatcccc tacacccacatgaacgggggcaagaggaacggccgcatcctgaccctgccgcggtccgac ccttcctaa

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