Camelus ferus (Wild Bactrian camel): 102524299
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Entry
102524299 CDS
T02979
Symbol
ITCH
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog isoform X1
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
cfr
Camelus ferus (Wild Bactrian camel)
Pathway
cfr04120
Ubiquitin mediated proteolysis
cfr04144
Endocytosis
cfr04330
Notch signaling pathway
cfr04668
TNF signaling pathway
cfr04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
cfr00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
102524299 (ITCH)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
102524299 (ITCH)
04668 TNF signaling pathway
102524299 (ITCH)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
102524299 (ITCH)
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
102524299 (ITCH)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
cfr04131
]
102524299 (ITCH)
04121 Ubiquitin system [BR:
cfr04121
]
102524299 (ITCH)
Enzymes [BR:
cfr01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
102524299 (ITCH)
Membrane trafficking [BR:
cfr04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
102524299 (ITCH)
Ubiquitin system [BR:
cfr04121
]
Ubiquitin ligases (E3)
HECT type E3
102524299 (ITCH)
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
102524299
NCBI-ProteinID:
XP_006190838
UniProt:
A0A8B7KDW7
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Position
19:37425794..37520549
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AA seq
862 aa
AA seq
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MSDSGSQLGSMGSLTMKSQLQITVISAKLKENKKNWFGPSPYVEVTVDGQSKKTEKCNNT
NSPKWKQPLTVIVTPVSKLHFRVWSHQTLKSDVLLGTAALDIYETLKSNNMKFEEVVVTL
QLVGDKEPTETIGDLSICLDGLQLDSEVVTNGETTCSQSASQNDDGSRPKDETRVNTNGS
DEPEDAGSGENRRVNGNNSPSLSNGSFKPSRPPRPSRPPPPTPRRPASVNGSPSTTSESD
GSSTGSLPPMNTNSNTSEGATSGLIIPLTISGGSGPRPLNPVPQATLPPGWEQRVDQHGR
IYYVDHVEKRTTWDRPEPLPPSWERRVDNMGRIYYVDHFTRTTTWQRPTLESVRNYEQWQ
LQRSQLQGAMQQFNQRFIYGNQDLFATSQNKEFDPLGPLPPGWEKRTDSNGRVYFVNHNT
RITQWEDPRNQGQLNEKPLPEGWEMRFTVDGIPYFVDHNRRTTTYIDPRTGKSALDNGPQ
IAYVRDFKAKVQYFRFWCQQLAMPQHIKITVTRKTLFEDSFQQIMSFSPQDLRRRLWVIF
SGEEGLDYGGIAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFI
GRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESVDPEFYNSLIWVKENNIEECGL
EMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGF
NEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYTRTSKQIVWFWQFVKEIDN
EKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPPYK
SYEQLKEKLLFAIEETEGFGQE
NT seq
2589 nt
NT seq
+upstream
nt +downstream
nt
atgtctgacagtggatcacagcttggttcaatgggtagcctgaccatgaaatcacaactt
cagattactgtcatttcagcaaaacttaaagaaaataaaaagaattggtttggaccaagt
ccgtatgtggaagtcactgtagatggacagtcaaagaagacagaaaaatgcaacaatacg
aacagtcccaaatggaagcagcctcttacagttattgttacccctgtgagtaaattacat
tttcgtgtgtggagtcaccagacactgaaatctgatgttttgttgggaactgctgcatta
gatatctatgaaacattaaagtcaaacaatatgaaatttgaggaagtagttgtgacttta
cagctggtaggtgacaaagaaccaacagagacaataggagatttgtcgatttgtcttgat
gggctgcagttagattcagaagttgttactaacggtgaaactacgtgttcacaaagtgct
tcacagaatgatgatggctccagacccaaggatgaaacaagagtgaacacaaatggatct
gacgaacctgaggatgcagggtctggtgaaaataggagagtcaatgggaacaattctcca
tcactctcaaatggcagttttaaaccttctaggcctccaagaccttcacgaccacctcca
cctaccccacgtagaccagcatctgtcaatggttcaccatcaaccacttctgaaagtgat
ggctctagtacgggctctctgccaccaatgaatacaaattcaaatacatctgaaggagca
acatctggattaataattcctcttactatatctggaggctcaggccctagaccattaaat
cctgtacctcaagctaccctcccacctggttgggagcagagagtggaccagcatggacga
atttactatgtagatcatgttgaaaaaagaacaacatgggatagaccagaacctctacct
cctagttgggaacggcgggttgacaacatgggacgtatttattacgttgaccatttcaca
agaacaacgacgtggcagaggccaacattggaatctgtccggaactatgaacaatggcag
ctccaacgaagtcaacttcaaggagctatgcagcagtttaaccagagattcatttatggg
aatcaagatttgtttgctacatcacaaaataaagaatttgatcccctcggtcccctgcca
cctggatgggagaagagaacggacagcaatggtagagtatattttgtcaaccacaacact
cgtattacacaatgggaggaccccagaaatcaaggtcaattaaatgaaaagcccttacct
gaaggctgggaaatgagatttacagtggatggaattccatattttgtggaccacaataga
agaacaaccacttatatagatccccgcactggaaaatctgccttagacaatggaccccag
atagcctatgtacgggacttcaaggcaaaggttcagtatttccggttctggtgtcagcaa
ctggccatgccacagcatataaagattaccgtgacaagaaaaacattgtttgaggattct
tttcagcagataatgagcttcagtccccaagatctgcgaagacgtttgtgggtgattttt
tcaggagaagaaggtttagattatggaggtatagcaagagaatggttctttcttttgtca
catgaggtgttgaacccaatgtattgcctgtttgaatatgcagggaaggataactactgc
ctacagataaatcctgcttcttacatcaatccggatcacctgaaatattttcgttttatt
ggcaggtttattgctatggctctgttccatgggaaattcatagacacaggtttttctttg
ccattctataagcgtatcttgaacaaaccagttggactcaaggatttagaatctgttgat
ccagaattttacaattctctcatctgggttaaagaaaacaatattgaggagtgtggtttg
gaaatgtatttttccgtcgataaagaaattttgggtgaaatcaagagtcatgatttgaaa
cccaatggcggcaatattcttgtaacagaagaaaataaagaggaatatatcagaatggta
gctgaatggaggttgtctcgtggtgttgaagaacagacacaagctttctttgagggcttt
aacgaaattcttccccagcagtatttgcaatattttgatgcaaaggaattagaggtcctt
ctgtgtggaatgcaagagattgatttgaatgactggcaaagacatgccatctaccgtcat
tacactaggacaagcaaacaaatcgtgtggttttggcagtttgttaaagaaatcgataat
gagaagagaatgagacttttgcagtttgttactggaacctgccgattaccagtcggagga
tttgctgacctcatggggagcaatggaccacagaaattctgcattgaaaaagttgggaaa
gaaaactggttacccagaagtcatacctgttttaaccgcctggacctgccaccctataag
agctatgagcaactgaaggaaaagctgttatttgccattgaagaaacagaaggatttgga
caagagtga
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