KEGG   Cricetulus griseus (Chinese hamster): 100689028
Entry
100689028         CDS       T02813                                 
Symbol
Dhfr
Name
(RefSeq) dihydrofolate reductase
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
cge  Cricetulus griseus (Chinese hamster)
Pathway
cge00670  One carbon pool by folate
cge00790  Folate biosynthesis
cge01100  Metabolic pathways
cge01240  Biosynthesis of cofactors
cge01523  Antifolate resistance
cge04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:cge00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    100689028 (Dhfr)
   00670 One carbon pool by folate
    100689028 (Dhfr)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    100689028 (Dhfr)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    100689028 (Dhfr)
Enzymes [BR:cge01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     100689028 (Dhfr)
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-GeneID: 100689028
NCBI-ProteinID: NP_001230945
UniProt: P04753 A0A9J7CH09
LinkDB
Position
2:311116057..311139836
AA seq 187 aa
MVRPLNCIVAVSQNMGIGKNGDFPWPMLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFS
IPEKNRPLKDRINIVLSRELKEPPQGAHFLAKSLDDALKLIEQPELADKVDMVWIVGGSS
VYKEAMNQPGHLRLFVTRIMQEFETDTFFPEIDLEKYKLLPEYPRVLPEVQEEKGIKYKF
EVYEKKG
NT seq 564 nt   +upstreamnt  +downstreamnt
atggttcgaccgctgaactgcatcgtggccgtgtcccagaatatgggcatcggcaagaac
ggagattttccctggccaatgctcaggaacgaattcaagtacttccaaagaatgaccacc
acctcctcagtggaaggtaaacagaacttggtgattatgggccggaaaacttggttctcc
attcctgagaagaatcgacctttaaaggacagaattaatatagttctcagtagagagctc
aaggaaccaccacaaggagctcattttcttgccaaaagtctggacgatgccttaaaactt
attgaacaaccagagttagcagataaagtggacatggtttggatagttggaggcagttcc
gtttacaaggaagccatgaatcagccaggccatctcagactctttgtgacaaggatcatg
caggaatttgaaactgacacgttcttcccagaaattgatttggagaaatataaacttctc
ccagagtacccaagggtccttcctgaagtccaagaggaaaaaggcatcaagtataaattt
gaagtctatgagaagaaaggctaa

DBGET integrated database retrieval system