Cricetulus griseus (Chinese hamster): 100689369 Help Entry 100689369         CDS       T02813                                  Symbol Casp8 Name (RefSeq) caspase-8   KO K04398   caspase 8 [EC:3.4.22.61] Organism cge  Cricetulus griseus (Chinese hamster) Pathway cge01524   Platinum drug resistance cge04115   p53 signaling pathway cge04210   Apoptosis cge04215   Apoptosis - multiple species cge04217   Necroptosis cge04620   Toll-like receptor signaling pathway cge04621   NOD-like receptor signaling pathway cge04622   RIG-I-like receptor signaling pathway cge04623   Cytosolic DNA-sensing pathway cge04625   C-type lectin receptor signaling pathway cge04657   IL-17 signaling pathway cge04668   TNF signaling pathway cge04932   Non-alcoholic fatty liver disease cge04936   Alcoholic liver disease cge05010   Alzheimer disease cge05016   Huntington disease cge05022   Pathways of neurodegeneration - multiple diseases cge05132   Salmonella infection cge05134   Legionellosis cge05142   Chagas disease cge05145   Toxoplasmosis cge05152   Tuberculosis cge05160   Hepatitis C cge05161   Hepatitis B cge05162   Measles cge05163   Human cytomegalovirus infection cge05164   Influenza A cge05165   Human papillomavirus infection cge05167   Kaposi sarcoma-associated herpesvirus infection cge05168   Herpes simplex virus 1 infection cge05169   Epstein-Barr virus infection cge05170   Human immunodeficiency virus 1 infection cge05200   Pathways in cancer cge05203   Viral carcinogenesis cge05416   Viral myocarditis cge05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:cge00001]  09130 Environmental Information Processing   09132 Signal transduction    04668 TNF signaling pathway     100689369 (Casp8)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     100689369 (Casp8)    04215 Apoptosis - multiple species     100689369 (Casp8)    04217 Necroptosis     100689369 (Casp8)    04115 p53 signaling pathway     100689369 (Casp8)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     100689369 (Casp8)    04621 NOD-like receptor signaling pathway     100689369 (Casp8)    04622 RIG-I-like receptor signaling pathway     100689369 (Casp8)    04623 Cytosolic DNA-sensing pathway     100689369 (Casp8)    04625 C-type lectin receptor signaling pathway     100689369 (Casp8)    04657 IL-17 signaling pathway     100689369 (Casp8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100689369 (Casp8)    05203 Viral carcinogenesis     100689369 (Casp8)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     100689369 (Casp8)    05161 Hepatitis B     100689369 (Casp8)    05160 Hepatitis C     100689369 (Casp8)    05164 Influenza A     100689369 (Casp8)    05162 Measles     100689369 (Casp8)    05168 Herpes simplex virus 1 infection     100689369 (Casp8)    05163 Human cytomegalovirus infection     100689369 (Casp8)    05167 Kaposi sarcoma-associated herpesvirus infection     100689369 (Casp8)    05169 Epstein-Barr virus infection     100689369 (Casp8)    05165 Human papillomavirus infection     100689369 (Casp8)   09171 Infectious disease: bacterial    05132 Salmonella infection     100689369 (Casp8)    05134 Legionellosis     100689369 (Casp8)    05152 Tuberculosis     100689369 (Casp8)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     100689369 (Casp8)    05142 Chagas disease     100689369 (Casp8)   09164 Neurodegenerative disease    05010 Alzheimer disease     100689369 (Casp8)    05016 Huntington disease     100689369 (Casp8)    05022 Pathways of neurodegeneration - multiple diseases     100689369 (Casp8)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     100689369 (Casp8)    05416 Viral myocarditis     100689369 (Casp8)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     100689369 (Casp8)    04932 Non-alcoholic fatty liver disease     100689369 (Casp8)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     100689369 (Casp8)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:cge01002]     100689369 (Casp8) Enzymes [BR:cge01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.61  caspase-8      100689369 (Casp8) Peptidases and inhibitors [BR:cge01002]  Cysteine peptidases   Family C14: caspase family    100689369 (Casp8) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Peptidase_C14 DED COG3_C PYRIN Motif Other DBs NCBI-GeneID:  100689369 NCBI-ProteinID:  NP_001233725 UniProt:  B2CMK5 LinkDB All DBs Position 2:413111289..413138540 Genome browser AA seq 481 aa AA seqDB search MDFRNCLYKIAENLDSSELAALKFLCLDYIPQKKQEPIKDALMLFQVLQEKGLLEEDNLS FLKELIFLINRLDLLSNTLNSSKEEMVRELQVPDKAQVSAYRVMLFKLSEEVTKSELKSF KFFLNEEIPKCKLYDDNSSLLDIFVEMEKRVILREENLDALKSICAQVNKSLLEKIEAYE KSSRGRMSLEGGAESPVSVLDGESYFRMQETWDSQREQDSDSQVSHRIYQMKSKPRGYCL IINNNDFSEARKNIPRFHKMKDRKGTNYDEEALTETFKELHFEVKPYRDCTANKIHEVLR FYQSMDHKDKDCFICCILSHGDTGIIYGTDGKEAPIYELTSYFTGSECPSLAGKPKIFFI QACQGDNYQKAVLVETDWEEMVSFLDVDSSQKSYIPDEADFLLGMATVKNCVSYRDPTQG TWYIQSLCQSLRKRCPQGDDILSILTGVNYDVSNKDDRKNMGKQMPQPIFTLRKKLFFPP K NT seq 1446 nt NT seq  +upstreamnt  +downstreamnt atggatttcagaaactgtctttacaagattgctgaaaacctggatagcagtgaactggct gccctcaagtttctgtgcttggactacatcccacagaagaagcaggagcccatcaaggat gccctgatgctatttcaggtactgcaggaaaagggactgttggaggaagacaatctgtcc ttcctgaaggagctgattttcctcatcaatcggctggacctgctgagcaacaccctaaac agcagcaaggaggagatggtgagggagctgcaggttccagacaaagcccaggtttctgcc tacagggtcatgctctttaagctctcagaagaagtgaccaagtcagaattgaaatctttt aagttttttttgaatgaagagattcctaaatgtaagctgtatgatgataactcgagcctg cttgatatttttgtggaaatggagaaaagagtcatcctgagggaagaaaacttggatgcc ctgaaatcaatctgtgcccaggtcaacaagagcctgctggagaagattgaggcttatgaa aaatcaagcagagggagaatgagccttgaaggaggggcagagtcgccagtttcagtttta gatggggagagttacttcagaatgcaggaaacgtgggactcccaaagagaacaagacagc gactcacaggtatcacacagaatttaccaaatgaagagcaaacctcggggatactgtctg atcatcaacaataatgatttcagtgaggcgaggaagaacatacccagattccacaaaatg aaggacagaaaaggaacaaactacgatgaagaggcattgactgagacctttaaagagctt cattttgaggtcaagccttacagagactgcacagccaataaaatccatgaggttctaaga ttctaccaaagcatggaccacaaggacaaggactgcttcatctgctgcatcctctcccat ggagacacgggcatcatctacggcactgatgggaaggaagcccccatttatgaactgaca tcttatttcactggttcagagtgcccttccctggctggaaaacccaaaatcttttttatt caggcttgccaaggggataactaccagaaagctgtacttgttgagactgactgggaagag atggtcagcttcttagacgtggactcatctcaaaagagctatattccagatgaggctgac tttctgttggggatggctactgtgaaaaactgtgtttcctaccgagatcccacgcaggga acctggtacatccagtcactttgccagagcctgaggaaaagatgtcctcaaggcgacgat attctcagcatcctgactggtgtgaactatgatgtgagcaataaggatgacagaaagaac atggggaagcagatgcctcagcccatcttcacactacggaagaagctgtttttccctcct aagtga

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