Cricetulus griseus (Chinese hamster): 100755710 Help Entry 100755710         CDS       T02813                                  Symbol Irs1 Name (RefSeq) insulin receptor substrate 1   KO K16172   insulin receptor substrate 1 Organism cge  Cricetulus griseus (Chinese hamster) Pathway cge04022   cGMP-PKG signaling pathway cge04068   FoxO signaling pathway cge04081   Hormone signaling cge04140   Autophagy - animal cge04150   mTOR signaling pathway cge04151   PI3K-Akt signaling pathway cge04152   AMPK signaling pathway cge04211   Longevity regulating pathway cge04213   Longevity regulating pathway - multiple species cge04722   Neurotrophin signaling pathway cge04910   Insulin signaling pathway cge04920   Adipocytokine signaling pathway cge04923   Regulation of lipolysis in adipocytes cge04930   Type II diabetes mellitus cge04931   Insulin resistance cge04932   Non-alcoholic fatty liver disease cge04935   Growth hormone synthesis, secretion and action cge04960   Aldosterone-regulated sodium reabsorption cge05010   Alzheimer disease cge05206   MicroRNAs in cancer cge05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:cge00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     100755710 (Irs1)    04022 cGMP-PKG signaling pathway     100755710 (Irs1)    04151 PI3K-Akt signaling pathway     100755710 (Irs1)    04152 AMPK signaling pathway     100755710 (Irs1)    04150 mTOR signaling pathway     100755710 (Irs1)   09133 Signaling molecules and interaction    04081 Hormone signaling     100755710 (Irs1)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     100755710 (Irs1)  09150 Organismal Systems   09152 Endocrine system    04923 Regulation of lipolysis in adipocytes     100755710 (Irs1)    04935 Growth hormone synthesis, secretion and action     100755710 (Irs1)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     100755710 (Irs1)   09156 Nervous system    04722 Neurotrophin signaling pathway     100755710 (Irs1)   09149 Aging    04211 Longevity regulating pathway     100755710 (Irs1)    04213 Longevity regulating pathway - multiple species     100755710 (Irs1)  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     100755710 (Irs1)   09164 Neurodegenerative disease    05010 Alzheimer disease     100755710 (Irs1)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     100755710 (Irs1)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     100755710 (Irs1)    04932 Non-alcoholic fatty liver disease     100755710 (Irs1)    04931 Insulin resistance     100755710 (Irs1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  IRS PH PH_11 Motif Other DBs NCBI-GeneID:  100755710 NCBI-ProteinID:  XP_027253161 UniProt:  A0A9J7FAG9 LinkDB All DBs Position 2:complement(434639615..434694587) Genome browser AA seq 1233 aa AA seqDB search MASPPDTDGFSDVRKVGYLRKPKSMHKRFFVLRAASEAGGPARLEYYENEKKWRHKSSAP KRSIPLESCFNINKRADSKNKHLVALYTRDEHFAIAADSEAEQDSWYQALLQLHNRAKAH HDGAGGGGCGGSCSGSSGVGEAGEDLSYDTGPGPAFKEVWQVILKPKGLGQTKNLIGIYR LCLTSKTISFVKLNSEAAAVVLQLMNIRRCGHSENFFFIEVGRSAVTGPGEFWMQVDDSV VAQNMHETILEAMRAMSDEFRPRSKSQSSSSCSNPISVPLRRHHLNNPPPSQVGLTRRSR TESITATSPASMVGGKPGSFRVRASSDGEGTMSRPASVDGSPVSPSTNRTHAHRHRGSSR LHPPLNHSRSIPMPSSRCSPSATSPVSLSSSSTSGHGSTSDCLFPRRSSASVSGSPSDGG FISSDEYGSSPCDFRSSFRSVTPDSLGHTPPARGEEELSNYICMGGKGASTLTAPNGHYI LSRGGNGHRYIPGANLGTSPALTGDEATSAADLDNRFRKRTHSAGTSPTISHQKTPSQSS VASIEEYTEMMPAAYPPGGGSGGRLPSYRHSAFVPTHSYPEEGLEMHPLERRGGHHRPDT STLHTDDGYMPMSPGVAPVPSNRKGNGDYMPMSPKSVSAPQQIINPIRRHPQRVDPNGYM MMSPSGSCSPDIGGGSSSSSGAAASGSSYGKPWTNGVGGHHSHALPHSKPPTESGSGKLL PCTGDYMNMSPVGDSNTSSPSECYYGPEDPQHKPVLSYYSLPRSFKHTQRPGEPEEGARH QHLRLSSSSGRLLYAATAEDSSSSTSSDSLGGAYCGARPESGLPHPHHHVVQPHGPRKVD TAAQTNRRLPRPTRLSLGDPKASTLPRVREQQQPSLHPPEPKSPGEYVNIEFGSGQPGYL AGPATSHSSPSVRCPPQLHPAPREETGSEEYMNMDLGPGRRATWQESGGVELGRVGPAPP GAATICRPTRSVPGSRGDYMTMQIGCPRQSYVDTSPVAPVSYADMRTSIGAEKVSLPRTT GAAPSSSSTASASPAAPEGAAEQAAHSSLLGGPQGPGGMSAFTRVNLSPNHNQSAKVIRA DTQGCRRRHSSETFSAPTRAGNTVSFGAGAAVGGSGGGAGGGSSSSEDVKRHSSASFENV WLRPGDLGGASKETAQVCGAAGGLESNLNYIDLDLAKDVRQRPQECPSQQQPLPPPAPHQ PSRNNEGSSPRRSSEDLSTYASINFQKQPEDHQ NT seq 3702 nt NT seq  +upstreamnt  +downstreamnt atggcgagccctccggataccgatggcttctcggacgtgcgcaaggtgggctacctgcgc aaacccaagagtatgcacaagcgctttttcgtactgcgggcagccagcgaggccgggggc ccggcgcgcctggaatactatgagaacgagaagaagtggcggcacaagtcgagcgccccc aaacgctcgatccccttggagagctgtttcaacatcaacaagcgggctgactccaagaac aagcacctggtggctctctacacccgagacgaacactttgccattgcggcagatagcgag gctgagcaagacagctggtaccaggctcttctgcagctgcataaccgagcaaaggcccac catgacggcgctggaggtggaggctgcggcggtagttgcagcggcagctctggcgtcgga gaagcaggggaggacttgagctatgacacgggcccaggacctgcgttcaaggaggtctgg caggttatcctgaaacccaaaggtctgggtcagacaaagaacttaattggcatctaccgc ctctgcctgaccagcaagaccatcagctttgtgaagctcaactccgaggcagcggctgtg gtgctacagctaatgaacatcagacgctgtggccactcagagaacttcttcttcatcgag gtggggcgttctgccgtgacaggacccggcgagttctggatgcaagtggatgactccgtg gtagcccagaacatgcatgagaccattctagaggccatgcgggccatgagcgatgagttt cgcccacgcagcaaaagccagtcttcatccagttgctccaaccccatcagtgttcccctt cgcaggcaccacctcaacaaccctccacccagccaggtggggctgactcgccgatctcgc actgagagcatcaccgccacctcccctgccagcatggtgggagggaaaccaggttccttc cgagtgcgagcctccagcgatggcgaaggcaccatgtcccgtccagcatcagtggatggt agtcctgtgagcccgagcaccaacaggacccacgcccatcggcaccgagggagctccagg cttcaccccccactcaaccacagccgctccatccctatgccttcttcccgctgctcacct tcagccaccagcccagtaagtctgtcatccagtagcactagtggccatggctccacctca gactgtctcttcccgagacgatctagtgcttccgtgtcaggttctcctagtgatggcggt ttcatctcttctgatgagtatggttctagtccctgcgatttccgcagttccttccgcagt gtcaccccagattccctgggtcacaccccaccagccaggggtgaggaagaactgagcaac tatatctgcatgggtggcaagggagcctccaccctgactgctcccaatggtcactacatt ttgtctaggggtggcaatggccatcgctacatcccaggtgctaacttggggacaagccca gcgttgactggggatgaagccaccagtgcagcagatctggacaaccggtttcggaagaga actcactccgcaggcacgtcccctaccatttcccatcagaagaccccctcgcagtcttca gtggcttctattgaggagtatacagagatgatgcctgctgcctacccaccaggaggtggc agtggaggccgactgcccagctatcggcattccgccttcgtgcccacccactcctacccc gaagagggtctcgagatgcaccccttggagcgtcgtgggggccaccaccgtccagacacc tccaccctgcacactgatgatggctacatgcccatgtctccaggggtggcgccagtgcca agcaaccgtaaagggaatggggactatatgcccatgagccccaagagtgtctctgcccca caacagatcattaaccccatcagacgtcaccctcagagagtggaccccaatggctacatg atgatgtctcccagtggcagttgctcccctgacattggaggtgggtccagcagcagcagc ggtgcagccgcttcggggagtagctacgggaagccatggacaaatggagtaggggggcac catagtcatgccctgcctcattccaaaccccctactgagagtggcagtggcaagctcttg ccctgcacaggcgactacatgaacatgtcaccagtgggagactccaacaccagcagcccc tcagaatgctactatggcccagaagatccccagcacaagccagtcctctcctactactca ttgccaaggtctttcaagcacacccagcgccctggggagccagaggagggtgccaggcac cagcatcttcgtctctcttctagctctggacgccttctctatgctgcaactgcagaagat tcttcctcttctaccagcagtgacagcctgggtggggcttactgtggggctaggccagag tccggcctcccacatccccaccaccatgtcgtgcaaccccatgggccccgaaaggtagac acggctgcacagaccaaccgccgcctgccccggcccacaaggctctccttgggagatccc aaggcaagtaccttaccccgggtacgggagcagcagcagccttcgttgcaccctcccgag cccaagagcccaggggaatatgtgaatattgaattcgggagtggccagcctggctattta gcgggcccggcgacttcccacagctctccttcggttcggtgtccaccccagctccaccca gctccccgagaagagactggctcagaagagtacatgaacatggacttggggccaggccgg agggcaacgtggcaggagagtggtggggttgagttgggtagagtaggccctgcacctcca ggggctgctaccatttgcaggccaacccggtcagtgccaggtagccgtggtgactacatg accatgcagataggttgtcctcgtcaaagctatgtggatacctcaccagtggccccagtc agctatgctgacatgcggacaagcattggcgccgagaaggtgagcctgcccagaaccaca ggggctgctccatcttcatcctccacagcctctgcttctcctgctgcacctgaaggcgca gctgagcaggctgctcactcttctctgctgggaggccctcagggacctgggggcatgagt gcattcaccagagtgaacctcagtcccaaccataaccagagtgccaaagtgattcgtgca gacactcaaggctgccggaggaggcacagctccgagaccttctcagcacctactcgggct ggcaacacggtgtcctttggagcaggggctgcagtagggggcagtggcggtggagctggc ggtggcagcagcagcagtgaggatgtaaaacgccacagctctgcatcatttgagaatgtg tggctgagacctggggatctagggggagcctccaaggagacggctcaagtgtgtggggct gctgggggtttggagagtaatcttaactacatagacctggatttagccaaggatgttaga cagcgtcctcaggaatgcccttctcaacagcagccccttccaccccctgcccctcaccag ccctcacgcaacaacgagggcagctcccccagacgctccagtgaggatttaagcacctat gccagcatcaacttccagaagcagccagaggaccatcaatag

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