Cricetulus griseus (Chinese hamster): 100759316
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Entry
100759316 CDS
T02813
Symbol
Lck
Name
(RefSeq) tyrosine-protein kinase Lck isoform X1
KO
K05856
lymphocyte cell-specific protein tyrosine kinase [EC:
2.7.10.2
]
Organism
cge
Cricetulus griseus (Chinese hamster)
Pathway
cge04064
NF-kappa B signaling pathway
cge04380
Osteoclast differentiation
cge04650
Natural killer cell mediated cytotoxicity
cge04658
Th1 and Th2 cell differentiation
cge04659
Th17 cell differentiation
cge04660
T cell receptor signaling pathway
cge05135
Yersinia infection
cge05166
Human T-cell leukemia virus 1 infection
cge05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
cge05340
Primary immunodeficiency
Brite
KEGG Orthology (KO) [BR:
cge00001
]
09130 Environmental Information Processing
09132 Signal transduction
04064 NF-kappa B signaling pathway
100759316 (Lck)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
100759316 (Lck)
04660 T cell receptor signaling pathway
100759316 (Lck)
04658 Th1 and Th2 cell differentiation
100759316 (Lck)
04659 Th17 cell differentiation
100759316 (Lck)
09158 Development and regeneration
04380 Osteoclast differentiation
100759316 (Lck)
09160 Human Diseases
09161 Cancer: overview
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
100759316 (Lck)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
100759316 (Lck)
09171 Infectious disease: bacterial
05135 Yersinia infection
100759316 (Lck)
09163 Immune disease
05340 Primary immunodeficiency
100759316 (Lck)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
cge01001
]
100759316 (Lck)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
cge03036
]
100759316 (Lck)
Enzymes [BR:
cge01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
100759316 (Lck)
Protein kinases [BR:
cge01001
]
Non-receptor tyrosine kinases
SRC family
100759316 (Lck)
Chromosome and associated proteins [BR:
cge03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
100759316 (Lck)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
SH2
SH3_1
SH3_2
SH3_9
ABC1
Haspin_kinase
SH3_16
SH2_1
SH3_3
DUF4390
Motif
Other DBs
NCBI-GeneID:
100759316
NCBI-ProteinID:
XP_035295490
UniProt:
A0A9J7GRE5
LinkDB
All DBs
Position
2:23479550..23490300
Genome browser
AA seq
458 aa
AA seq
DB search
MGCGCSSNPEDDWMENIDVCENCHYPIVPLDSKTTLPMRNGSEVRDPLVTYEGSIPPASP
LQDNLVIALHSYEPSHDGDLGFEKGEQLRILEQSGEWWKAQSLTTGQEGFIPFNFVAKAN
SLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKH
YKIRNLDNGGFYISPRITFPGLHELVRHYTRYYNGHTKVAVKSLKQGSMSPDAFLAEANL
MKQLQHQRLVRLYAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLNINKLLDMAAQIAEG
MAFIEEQNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEA
INYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQ
IMMLCWKERPEERPTFDYLRSVLDDFFTATEGQYQPQP
NT seq
1377 nt
NT seq
+upstream
nt +downstream
nt
atgggctgtggctgcagctcaaaccctgaagatgactggatggagaacattgatgtgtgt
gaaaactgccattatcccatagttccactggacagcaagaccacgctgcccatgcggaat
ggctctgaagttcgggacccactggtcacctatgagggctccatcccaccagcctccccg
ctgcaagacaacctagttatcgctctgcacagctatgaaccctcccatgatggagatctg
ggctttgagaagggtgaacagctccgaattctggagcagagcggtgagtggtggaaggct
cagtccctgaccaccggccaagaaggcttcatccccttcaacttcgtggcgaaggcaaac
agcctggagcctgaaccctggttcttcaagaatctgagccgtaaggacgctgagcggcag
cttttggcgcctgggaacacgcacggatccttcctgatccgggaaagtgaaagcaccgcg
ggatctttttcactgtcggtcagagacttcgaccagaaccagggagaagtggtgaaacat
tacaagatccgcaacctagacaacggtggcttctacatctcccctcgtatcacttttccc
ggcctgcacgagctggtccgccattacaccaggtactacaacgggcacacgaaggtggca
gtgaagagcctgaagcaagggagcatgtcccccgatgccttcctggcggaagctaacctc
atgaaacagctgcagcaccagcggctggtccggctttacgcagtggtcacccaggagccc
atctacatcatcacagaatacatggagaacgggagcctagtagattttctcaagactccc
tcaggcatcaaactgaacatcaacaagctgttggacatggcagcacagattgcagagggc
atggcattcattgaagagcaaaattacatccatcgcgaccttcgggctgccaacatcctg
gtgtccgacacattgagctgcaagattgcggactttggcctggcacgtctcattgaggac
aatgagtacacagccagggagggggccaaatttcccattaaatggacagcaccagaagcc
attaactatgggaccttcaccatcaagtccgatgtgtggtctttcgggatcttgctgaca
gagatcgtcacccatggcagaatcccttacccagggatgactaaccctgaagtgattcag
aatctggagcgaggctaccgcatggttcgacctgacaactgtccagaggagctgtaccaa
atcatgatgctatgctggaaggagcgtccagaggagcggcccacatttgactatcttcga
agtgttctggatgacttcttcacagccacggagggccagtaccagccccagccttga
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