Cricetulus griseus (Chinese hamster): 100760475
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Entry
100760475 CDS
T02813
Name
(RefSeq) receptor tyrosine-protein kinase erbB-4 isoform X2
KO
K05085
receptor tyrosine-protein kinase erbB-4 [EC:
2.7.10.1
]
Organism
cge
Cricetulus griseus (Chinese hamster)
Pathway
cge04010
MAPK signaling pathway
cge04012
ErbB signaling pathway
cge04020
Calcium signaling pathway
cge04151
PI3K-Akt signaling pathway
cge05014
Amyotrophic lateral sclerosis
cge05205
Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:
cge00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100760475
04012 ErbB signaling pathway
100760475
04020 Calcium signaling pathway
100760475
04151 PI3K-Akt signaling pathway
100760475
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
100760475
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
100760475
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
cge01001
]
100760475
Enzymes [BR:
cge01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
100760475
Protein kinases [BR:
cge01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
100760475
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
TM_ErbB1
Kinase-like
Haspin_kinase
ABC1
Motif
Other DBs
NCBI-GeneID:
100760475
NCBI-ProteinID:
XP_035294730
UniProt:
A0A9J7K3R5
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All DBs
Position
2:complement(421665542..422324509)
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AA seq
1293 aa
AA seq
DB search
MPTGCGHHHTFTGKVRYHYTVDMCAGTENKLSSLSDLEQQYRALRKYYENCEVVMGNLEI
TSIEHNRDLSFLRSIREVTGYVLVALNQFRYLPLENLRIIRGTKLYEDRYALAIFLNYRK
DGNFGLQELGLKNLTEILNGGVYVDQNKFLCYADTIHWQDIVRNPWPSNMTLVSTNGSSG
CGRCHKSCTGRCWGPTENHCQTLTRTVCAEQCDGRCYGPYVSDCCHRECAGGCSGPKDTD
CFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNFNAKYTYGAFCVKKCPHNFVVDSSSCV
RACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLMSAQTVDSSNIDKFINCTKINGN
LIFLVTGIHGDPYNAIEAIDPEKLNVFRTVREITGFLNIQSWPPNMTDFSVFSNLVTIGG
RVLYSGLSLLILKQQGITSLQFQSLKEISAGNIYITDNSNLCYYHTINWTTLFSTINQRI
VIRDNRRADNCTAEGMVCNHLCSSDGCWGPGPDQCLSCRRFSRGKICIESCNLYDGEFRE
FENGSICVECDSQCEKMEDGLLTCHGPGPDNCTKCSHFKDGPNCVEKCPDGLQGANSFIF
KYADQDRECHPCHPNCTQGCVGSSIEDCIGLMDRTPLIAAGVIGGLFIVVIMALTFAVYV
RRKSIKKKRALRRFLETELVEPLTPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKG
IWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLLGVCLSPTIQLV
TQLMPHGCLLDYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPN
HVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMT
FGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEFS
RMARDPQRYLVIQGDDRMKLPSPNDSKFFQNLLDEEDLEDMMDAEEYLVPQAFNIPPPIY
TSRARIDSNRSEIGHSPPPAYTPMSGNQFVYQDGGFATQQGISMPYRATTNTIPEAPVAQ
GATAEMFDDSCCNGTLRKPVAPHVQEDSSTQRYSADPTVFAPERNPRGELDEEGYMTPMR
DKPKQEYLNPVEENPFVSRRKNGDLQALDNPEYHSASSGPPKAEDEYVNEPLYLNTFANA
LGNAEYLKNSVLSVPDKAKKAFDNPDYWNHSLPPRSTLQHPDYLQEYSTKYFYKQNGRIR
PIVAENPEYLSEFSLKPGTMLPPPPYRHRNTVV
NT seq
3882 nt
NT seq
+upstream
nt +downstream
nt
atgcctacaggatgtggccaccaccacacgttcactggcaaagtaagatatcactacaca
gtagatatgtgcgcaggaacagagaataaactgagctctctctctgacctggaacagcag
taccgagccttgcgcaaatactatgagaactgcgaggtagtcatgggcaacctggagatc
accagcatcgaacacaaccgggacctctccttcctgcggtctatccgagaggtcacgggc
tacgtactggtggccctcaaccagttccgttacctgcctctggagaatttacgcattatt
cgtggaacaaaactgtatgaagatcgttatgccttagcgatattcctaaactacagaaaa
gatggcaattttggacttcaagaacttggattaaagaatctgactgaaattctaaatggt
ggagtttatgtagaccagaacaagttcctgtgttatgctgacaccatacactggcaagat
attgttcggaacccatggccttccaacatgactctggtgtcaacaaatggaagctctgga
tgtggaagatgccataagtcctgtactggccgctgctggggacccaccgaaaatcactgt
cagaccttgacaagaactgtgtgtgctgaacaatgtgacggcaggtgctatggaccctac
gttagtgactgctgccatcgagaatgtgctggaggctgctccggaccaaaggacactgac
tgctttgcctgcatgaacttcaatgacagtggggcttgtgttactcaatgtccccagaca
tttgtctacaatccaactacctttcaactggaacacaactttaatgcaaagtacacatat
ggagcattctgtgttaaaaaatgcccacataactttgtggtagattccagttcctgtgtg
cgtgcttgtcctagttccaagatggaagtagaagaaaatgggattaaaatgtgtaagcct
tgcaccgacatttgccctaaagcgtgtgatggcattggcacaggatcgttgatgtcagct
cagacagtggattccagtaatattgacaaattcataaactgcacaaagatcaatgggaat
ctcatcttccttgtcactgggattcacggggacccttacaatgcaattgaagccatagac
ccagagaagctgaatgtcttccggacagtcagagaaataacaggtttcctgaacatacaa
tcctggcctccaaacatgacagatttcagtgttttctccaaccttgtcaccattggaggg
cgagtcctctacagtggtctatcactgcttatcctcaaacaacaaggcatcacttccctg
caattccagtctctgaaggaaatcagtgcgggcaacatctacattactgacaacagcaac
ctgtgttattatcataccattaactggacaacgctctttagcaccattaaccagagaata
gtgatccgagataacagaagagctgacaactgtactgctgaagggatggtgtgcaatcac
ctgtgttcaagtgacggctgttggggacctggaccagaccagtgtctatcatgtaggcgc
ttcagcaggggaaaaatctgcatagaatcttgtaatctctatgatggggaatttcgagag
tttgaaaatggctccatctgtgttgaatgtgactctcagtgtgagaagatggaagatgga
ctactcacatgccatggaccgggacctgacaactgcacaaagtgttctcattttaaggat
ggtccaaactgtgtggagaaatgtccagatggcctacagggagcaaacagtttcattttc
aagtatgcggatcaggatcgggaatgccacccatgccatccaaactgcacccaagggtgc
gtaggctcaagtattgaagattgcatcggcctgatggatagaactccattgattgcagcc
ggagtcattggcggcctcttcatcgtggtcatcatggctctcacatttgcggtatatgtc
agaaggaagagcatcaaaaagaaacgagccctgaggagattcctagaaacagagctggtg
gagcccttaacccctagtggcacagcacccaaccaagctcaactacgcattttgaaggaa
acagaactaaagagggtaaaagtccttggctccggagcttttggaactgtttataaaggt
atttgggtgcctgaaggtgagacagtgaaaattcctgtggctattaagatcctcaatgag
acaactggccccaaagccaatgtggagttcatggatgaggctctgatcatggcaagcatg
gaccacccacacctagttcgcttactgggcgtgtgcctgagccccactatccagctagtt
acccaactgatgccccatggctgcctgctggactatgtccatgaacacaaggataacata
gggtcacagctgctgctgaactggtgtgtgcagattgctaagggaatgatgtacctggaa
gaaagacggcttgttcatcgggatctggcagctcgtaatgtcttagtaaaatccccaaat
catgtgaaaatcacagattttggactagccagactcttggaaggagatgaaaaggaatac
aacgctgatggtggcaagatgccaattaaatggatggccctggaatgtatacattatagg
aaattcactcatcaaagtgatgtttggagctatggagtcacaatatgggaactgatgacc
tttggaggaaaaccctatgatggaattccaacccgagaaatccctgatttattagagaaa
ggagagcgtttgcctcaacctcccatctgcactattgacgtttacatggtcatggtcaaa
tgttggatgatcgatgctgacagcaggcctaaattcaaggaactggctgctgagttttca
aggatggctagagaccctcaaagatacctagttattcagggtgatgatcggatgaagctt
ccaagtccaaatgacagcaaattcttccagaatctcttggatgaagaagatttggaagac
atgatggatgctgaggaatacttggtcccccaggctttcaacatccctcctcctatctac
acatccagagcaagaattgactccaataggagtgaaattggacacagccctcctcctgcc
tacacccccatgtcgggaaatcagtttgtgtaccaggatgggggctttgctacacaacaa
ggaatatccatgccctacagagccacaaccaacaccataccagaagctccagtcgctcag
ggtgcaacagctgagatgtttgatgactcctgctgcaatggtaccctacgcaagccagtg
gcaccccatgtccaagaggacagtagcacacagagatatagtgctgatcccacagtgttt
gccccggaacggaacccccgaggagaactggatgaagaaggctacatgactccaatgcgt
gacaaacccaaacaagaatatctgaatcctgtggaagaaaacccttttgtatctcggaga
aaaaacggagaccttcaagctttagataatccagagtaccacagcgcttcgagcggtccg
cccaaggcagaggatgagtatgtgaatgagccactctatctcaacaccttcgcaaacgcc
ttggggaacgcggagtacctgaagaacagcgtactgtctgtgcccgacaaagccaagaaa
gcattcgacaaccctgactactggaaccacagcctgccaccccggagcacccttcagcac
ccagactacctgcaggaatacagcacaaaatatttttataaacagaatggacggatccgc
cctattgtggcggagaatcctgagtacctctcggagttctcgctgaagccaggcactatg
ctgccccctccgccctacagacacaggaatactgtggtgtga
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