KEGG   Cricetulus griseus (Chinese hamster): 100764560
Entry
100764560         CDS       T02813                                 
Symbol
Fgfr3
Name
(RefSeq) fibroblast growth factor receptor 3 isoform X1
  KO
K05094  fibroblast growth factor receptor 3 [EC:2.7.10.1]
Organism
cge  Cricetulus griseus (Chinese hamster)
Pathway
cge01521  EGFR tyrosine kinase inhibitor resistance
cge04010  MAPK signaling pathway
cge04014  Ras signaling pathway
cge04015  Rap1 signaling pathway
cge04020  Calcium signaling pathway
cge04144  Endocytosis
cge04151  PI3K-Akt signaling pathway
cge04550  Signaling pathways regulating pluripotency of stem cells
cge04810  Regulation of actin cytoskeleton
cge05200  Pathways in cancer
cge05206  MicroRNAs in cancer
cge05219  Bladder cancer
cge05230  Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:cge00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100764560 (Fgfr3)
   04014 Ras signaling pathway
    100764560 (Fgfr3)
   04015 Rap1 signaling pathway
    100764560 (Fgfr3)
   04020 Calcium signaling pathway
    100764560 (Fgfr3)
   04151 PI3K-Akt signaling pathway
    100764560 (Fgfr3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    100764560 (Fgfr3)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    100764560 (Fgfr3)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    100764560 (Fgfr3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100764560 (Fgfr3)
   05206 MicroRNAs in cancer
    100764560 (Fgfr3)
   05230 Central carbon metabolism in cancer
    100764560 (Fgfr3)
  09162 Cancer: specific types
   05219 Bladder cancer
    100764560 (Fgfr3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    100764560 (Fgfr3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:cge01001]
    100764560 (Fgfr3)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:cge04090]
    100764560 (Fgfr3)
Enzymes [BR:cge01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     100764560 (Fgfr3)
Protein kinases [BR:cge01001]
 Receptor tyrosine kinases (RTK)
  FGFR family [OT]
   100764560 (Fgfr3)
CD molecules [BR:cge04090]
 Proteins
  100764560 (Fgfr3)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase I-set Ig_3 ig Ig_2 V-set FGFR3_TM C2-set_2 ABC1 Pkinase_fungal RFX5_DNA_bdg
Other DBs
NCBI-GeneID: 100764560
NCBI-ProteinID: XP_027243001
UniProt: A0A9J7EUZ9
LinkDB
Position
1
AA seq 803 aa
MVVPACVLAFCFAVLAGATSEPPGPEQRVVRRPAEVPGSEPSQQEQVAFGSGDTVELSCH
PPGGAPTGPTVWAKDGTGLVASHRILVGPQRLQVLNASHEDAGVYSCQQRLTQRVLCHFN
VRVTDAPSSGDDEDGEDVAEDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSI
SWLKNGKEFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVL
ERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYV
TVLKSWISENVEADARLRLANVSERDGGEYLCRATNFIGVAEKAFWLRVHGPQAAEEELM
EVDEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKVSRFPLKRQQV
SLESNSSMNSNTPLVRIARLSSGEGPVLANVSELELPADPKWELSRTRLTLGKPLGEGCF
GQVVMAEAIGIDKDRTAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLG
ACTQGGPLYVLVEYAAKGNLREFLRARRPPGMDYSFDACRLPEEQLTCKDLVSCAYQVAR
GMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAP
EALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDL
YMIMRECWHAVPSQRPTFKQLVEDLDRILTVTSTDEYLDLSVPFEQYSPGGQDTPSSSSS
GDDSVFTHDLLPSGPPTNGGPRT
NT seq 2412 nt   +upstreamnt  +downstreamnt
atggtagtcccagcctgcgtgctagcgttctgctttgcggtattggccggagctacctct
gaaccacccggcccagagcagcgagttgtgcggagacccgcagaggtcccagggtctgag
cctagccagcaggagcaggtggcctttggcagtggggacaccgtggagctaagctgccat
ccgcctggaggtgcccccacaggtcccactgtctgggctaaggatggcacagggctggtg
gcttcccaccgcatcttggtggggccccagaggctccaagtgctgaatgcctcccatgag
gatgcgggggtctacagctgccagcagcggctcactcagcgtgtgttgtgccacttcaat
gtgcgtgtgacagatgctccatcttcaggagacgacgaagatggggaggacgtggctgaa
gatacaggggccccttattggactcgaccagagcgtatggataagaaactgctggctgtg
ccagcagcaaacactgtacgtttccgctgcccagctgctggcaatcctaccccctccatc
tcctggctgaagaatggcaaagaattccgaggggagcatcgcatagggggcatcaagctt
cggcaccagcagtggagtctggtcatggagagtgtggtaccctctgatcgtggcaactat
acctgtgtggtagagaacaagtttggcagcatccggcagacgtacactctggatgtgcta
gagcgttccccacaccggcccatcctgcaggctgggctgccagccaaccagacagcagtt
ctgggcagtgacgtggagttccactgcaaggtgtacagcgatgcacagccacacatccag
tggctgaagcatgtggaagtgaatggcagcaaagtgggcccagacggcacaccctatgtc
actgtactcaagtcctggatcagtgagaatgtggaggcagacgcacgcctccgcctggcc
aatgtgtcggagcgggacgggggcgagtacctctgtcgagccaccaatttcataggcgtg
gctgagaaggccttttggctgcgtgttcacgggcctcaagcagctgaggaggagctgatg
gaagtcgatgaagctggcagcgtgtatgcaggcatcctcagctacggggtgggattcttc
ctcttcatcctggtggtggcagctgtgacgctctgtcgccttcgaagtcccccaaagaag
ggcctgggctcacccactgtgcacaaggtctctcgcttcccgcttaagcgacagcaggta
tccttggagtccaactcctctatgaactccaacacaccccttgtccgcattgcccggctg
tcctccggagaaggtcctgttctggctaatgtttctgaacttgagctgcctgctgacccc
aagtgggagctatccaggacccggctgacactcggtaagccccttggagaaggctgcttt
ggccaggttgtcatggcagaagctattggcattgacaaggaccgaactgccaagcctgtt
acggtggctgtgaagatgctgaaagatgatgccactgacaaggacctgtcggacctggtg
tctgagatggagatgatgaaaatgattggcaaacacaagaacatcatcaacctgctgggg
gcctgcacacagggtgggcccctgtatgtgctggtggagtatgcagccaagggcaaccta
cgagagttcctgcgggcacgacggcctccaggcatggactactcctttgatgcctgcagg
ctgccagaagaacagcttacttgcaaggatcttgtgtcttgtgcctaccaggtggcccgg
ggcatggaatacctggcttcccagaagtgcattcacagagacttggctgccagaaacgtg
ctggtgactgaggataatgtgatgaagattgcagactttggcctggcccgtgacgtgcat
aatctagactactacaagaagaccacaaatggccggctaccagtgaagtggatggcacca
gaggccctgtttgaccgagtctacacccaccagagtgatgtctggtcctttggggtcctt
ctctgggagatcttcacactggggggctcaccgtatcctggcatcccagtggaagagctc
ttcaagctattgaaagagggccaccgcatggacaagccagccaactgcacacatgacctg
tacatgatcatgcgggaatgttggcatgcggtaccttcacagaggcctaccttcaagcag
ctggtagaggacttagaccgcatccttactgttacgtcaactgatgaatacctggaccta
tcggtgccttttgagcagtactcgccaggtggccaggatactcctagctccagctcttca
ggagacgactctgtgttcacccatgatttgctgccctcaggtccacccactaatggggga
cctcggacgtga

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