Cricetulus griseus (Chinese hamster): 100764620
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Entry
100764620 CDS
T02813
Symbol
Alox12
Name
(RefSeq) polyunsaturated fatty acid lipoxygenase ALOX12 isoform X3
KO
K00458
arachidonate 12-lipoxygenase [EC:
1.13.11.31
]
Organism
cge
Cricetulus griseus (Chinese hamster)
Pathway
cge00590
Arachidonic acid metabolism
cge01100
Metabolic pathways
cge01523
Antifolate resistance
cge04726
Serotonergic synapse
cge04750
Inflammatory mediator regulation of TRP channels
Brite
KEGG Orthology (KO) [BR:
cge00001
]
09100 Metabolism
09103 Lipid metabolism
00590 Arachidonic acid metabolism
100764620 (Alox12)
09150 Organismal Systems
09156 Nervous system
04726 Serotonergic synapse
100764620 (Alox12)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
100764620 (Alox12)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
100764620 (Alox12)
Enzymes [BR:
cge01000
]
1. Oxidoreductases
1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
1.13.11 With incorporation of two atoms of oxygen
1.13.11.31 arachidonate 12-lipoxygenase
100764620 (Alox12)
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GFIT
Motif
Pfam:
Lipoxygenase
PLAT
Motif
Other DBs
NCBI-GeneID:
100764620
NCBI-ProteinID:
XP_027282737
UniProt:
A0A9J7JYW8
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Position
7:complement(84067242..84078962)
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AA seq
663 aa
AA seq
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MGRYRVRVATGAWLFSGSLNRVRLWLVGAHREAKLELQLRPVRGKEEEFDFDIPEDLGPL
QFVRLHKQHWVVDDAWFCNLITVQEPLTSAEAVFPCYCWLQGEGVLSLPEGTARLAGDNA
SDVFQKHREKELKERQQTYRWATWKEGLPQTIAADCKDDLPVNMRFHEEKRLDFEWTLKA
GVLEMRLKRIYTLLRSWNRLEDFDQIFWGQKSALAEKVHRCWQDDEFFGYQFLNGANPML
LRRCTSLPSRLVLPSGTEELQAQLDRELQNGSLFEVDFILLDGIPANVIGGEQQYLAAPL
VMLRMDPNGKLLPMAIQIQPPSPSSPAPTLFLPSDPPLAWLLAKIWVRSSDFQLHELQFH
LLNTHLVAEVIAVATMRCLPGLHPIFKLLVPHIRYTMEINTRSRTQLISDGGLFDQGVST
GGGGHIQLLTRALAQLTYSSLCPPEDLANRGLLRIPSALYAQDALQLWEVTARYVEGMVH
LFYQSDDIVRGDKELQAWCWEITEVGLCHAQDRGFPVSFQTRAQLCHFLTTCVFTCTSQH
AAINQGQMDWYGWVPNAPCTMRMPPPTNKEDVTMEMVMGSLPDIQKSCLQMTITWHLSRL
QPDMIPLGQHKEKYFSDPRTKTVLSRFQADLENLEREITARNEHLDLPYEYLKPSHIENS
ITI
NT seq
1992 nt
NT seq
+upstream
nt +downstream
nt
atgggccgctaccgcgtccgagtggccactggagcctggctcttctcgggatccctcaac
cgagtgcggctgtggctggttggggcgcatcgggaggcgaaactggagctgcagctgagg
ccggtgcggggcaaggaggaggaatttgacttcgatattcccgaggacttggggccactg
cagtttgtgagactgcacaaacagcactgggtggtggacgacgcctggttctgcaatctc
atcacggttcaggagcccttaacaagtgcagaggcagtattcccctgctactgctggctg
cagggagagggagtactgagcctgccggagggtacagcccgcctggcaggagacaatgcc
tcggatgtcttccagaagcatcgagaaaaggagctgaaggaaagacaacagacctaccgc
tgggccacctggaaggaaggcttacctcagacaatagcagcagactgtaaggatgaccta
cctgtgaatatgagattccatgaggagaagaggctggacttcgagtggacactgaaggca
ggggttctggaaatgcgtctcaaacgtatttacaccctgttgagaagctggaaccgtctg
gaagactttgatcagatcttctggggccagaagagtgccttggcagagaaggttcaccgc
tgctggcaggacgatgagttttttggctaccagttcctcaatggtgccaaccccatgctg
ttgagacgctgcacctctctgccctccaggctggtactgccctctgggacagaggagctc
caagcccagttggacagagaactccagaatggttccctgtttgaagttgactttatcctg
ctggatggaattccagccaatgtgatcggaggagaacagcagtacctggctgcccccctt
gtcatgctgaggatggaccccaatgggaagctgctacccatggctatccagattcagcct
cccagtcccagctccccagctccaacattgttcctgccctcagatcctccacttgcctgg
ctcttggctaagatctgggttcgaagttcagatttccagctgcacgagctccagttccat
ttgctgaatactcatctggtggctgaggtcatcgctgttgccaccatgaggtgcctccca
ggactgcaccctatcttcaagctcctagttccccacattcgttacactatggaaatcaac
acacgaagccggacccagctcatctcagatgggggactatttgatcagggagtgagcaca
ggtggagggggccacattcagttgctcactcgggcactggcacagctgacttactcctcc
ctctgtccccctgaagacctggctaaccgaggcctgctgagaatcccaagtgccctctat
gctcaggatgctttacagctctgggaagtcactgccaggtacgtggaggggatggtccac
ctcttctaccagagtgatgatatcgtgaggggagacaaagagctgcaggcctggtgttgg
gagatcactgaggtgggactgtgccatgcccaggacagaggtttccctgtctccttccag
acccgggctcagctctgccatttccttaccacgtgtgtcttcacatgtacttcccagcat
gctgccatcaaccagggccagatggactggtatggttgggtacctaatgctccatgcaca
atgaggatgcccccacccaccaacaaggaagatgtgacaatggagatggtgatggggtcg
ctacctgatattcagaagtcctgtcttcaaatgaccatcacatggcatctaagtcgcctc
cagccggacatgatacctctaggacaacacaaagaaaagtatttctcagatcccaggacc
aaaactgtgctgagccgatttcaagcagatttggaaaatttggaaagagagattacagcc
cggaatgagcaccttgacctgccctatgaatacctcaagcccagccacatagagaacagt
atcaccatctga
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