Cricetulus griseus (Chinese hamster): 100764950
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Entry
100764950 CDS
T02813
Symbol
Bace2
Name
(RefSeq) beta-secretase 2 isoform X2
KO
K07747
beta-site APP-cleaving enzyme 2 (memapsin 1) [EC:
3.4.23.45
]
Organism
cge
Cricetulus griseus (Chinese hamster)
Pathway
cge05010
Alzheimer disease
Brite
KEGG Orthology (KO) [BR:
cge00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
100764950 (Bace2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
cge01002
]
100764950 (Bace2)
Enzymes [BR:
cge01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.23 Aspartic endopeptidases
3.4.23.45 memapsin 1
100764950 (Bace2)
Peptidases and inhibitors [BR:
cge01002
]
Aspartic peptidases
Family A1: pepsin family
100764950 (Bace2)
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Asp
TAXi_C
TAXi_N
Motif
Other DBs
NCBI-GeneID:
100764950
NCBI-ProteinID:
XP_027271511
UniProt:
A0A8C2LK34
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Position
4:complement(589608..668423)
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AA seq
514 aa
AA seq
DB search
MGAQLRALLLPLLAQWLLRATTALAPAPFTLPLQVSAATSLVASAVPGLGTPEKPRADGL
ALALEPSGAAANFLAMVDNLQGDSGRGYYLEMLIGTPPQKLQILVDTGSSNFAVAGAPHS
YVDSYFDSERSSTYHPKGFDVTVKYTQGSWTGIVGEDIVTIPKGFNSSFLVNIATIFESE
NFFLPGIKWNGILGLAYAALAKPSSSLETFFDSLVAQAKIPDIFSMQMCGAGLPVAGSGT
NGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDS
GTTLLRLPQKVFDAVVEAVARTSLIPEFSDGFWTGAQLACWTNSETPWAYFPKISIYLRD
ENSSRSFRITILPQLYIQPMMGAGLNYECYRFGISSSTNALVIGATVMEGFYVVFDRARK
RVGFAASPCAEIEGTTVSEISGPFSTEDVASNCVPAPALNEPILWIVSYALMSVCGAILL
VLILLLLLPVRCRHAPRDPEVVNDESSLVRHRWK
NT seq
1545 nt
NT seq
+upstream
nt +downstream
nt
atgggcgcgcagctccgagcgcttctgctcccgctgttggcgcagtggctcttgcgcgca
accaccgcgttggccccggcgcccttcacgctaccccttcaggtgtctgcagccacaagc
ctcgtagcctcggcagttcccgggctcgggacccctgagaagccccgtgcagatggcctg
gcgctagcgctggagccctccggggctgccgccaacttcttggctatggtggacaacctg
cagggggactctggccgcggctactacctggagatgctgatcgggaccccgccacagaag
ctacagattcttgtggacactggaagcagtaacttcgctgtggccggtgccccacattcc
tacgtagactcctactttgactcagagagatccagcacataccaccctaagggctttgat
gtcactgtgaagtacacacagggaagctggactggcatcgttggtgaggatattgtcacc
atccccaaaggcttcaacagctctttcctggtcaacattgccactatttttgagtctgag
aatttctttttgcctgggattaagtggaatggaattctcggacttgcttatgctgccttg
gccaagccatcaagctctcttgagaccttctttgattccctggtggcccaagcgaagatt
ccagacattttctccatgcagatgtgtggggccggattgccagtagccggatctggtacc
aacggaggtagtcttgtgctgggtgggattgaaccaagtttgtataaaggagacatctgg
tatacccccattaaagaggaatggtactatcagatagagatcctgaaattggaaattgga
ggccaaagcctcaacctggactgcagagagtataatgcggacaaggccattgtggacagc
ggcaccacactcctgcgcctgccccagaaggtgtttgatgcggtggtggaagctgtggcc
cgcacatctctgattccagagttttctgatggcttctggacaggggcccagctggcatgc
tggacaaattctgaaacgccatgggcatatttccctaagatctctatctacctgagagat
gagaactccagtcgctccttccgcatcactattctgccacagctctacattcagcccatg
atgggagctggtctcaattatgaatgctaccgttttggtatctcctcttccacaaatgca
ctggtgattggtgctacggtgatggagggcttctacgtggtctttgacagagctcggaag
agagtgggctttgcagcaagtccctgtgcagagatcgaaggtaccacagtgtcagaaatc
tccgggcccttttccactgaagatgtagccagcaactgtgtcccagcaccagctctgaat
gagcccatcttgtggattgtgtcctatgccctgatgagcgtgtgtggagccatcctcctt
gttctgatcctcctgctgctgctcccggtgcgctgccgacatgctccccgagaccctgag
gtcgttaatgatgagtcctcactggtcagacatcgctggaaatga
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