Cricetulus griseus (Chinese hamster): 100770724
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Entry
100770724 CDS
T02813
Symbol
Brca1
Name
(RefSeq) breast cancer type 1 susceptibility protein isoform X1
KO
K10605
breast cancer type 1 susceptibility protein [EC:
2.3.2.27
]
Organism
cge
Cricetulus griseus (Chinese hamster)
Pathway
cge01524
Platinum drug resistance
cge03440
Homologous recombination
cge03460
Fanconi anemia pathway
cge04120
Ubiquitin mediated proteolysis
cge04151
PI3K-Akt signaling pathway
cge05206
MicroRNAs in cancer
cge05224
Breast cancer
Brite
KEGG Orthology (KO) [BR:
cge00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
100770724 (Brca1)
09124 Replication and repair
03440 Homologous recombination
100770724 (Brca1)
03460 Fanconi anemia pathway
100770724 (Brca1)
09130 Environmental Information Processing
09132 Signal transduction
04151 PI3K-Akt signaling pathway
100770724 (Brca1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
100770724 (Brca1)
09162 Cancer: specific types
05224 Breast cancer
100770724 (Brca1)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
100770724 (Brca1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
cge01009
]
100770724 (Brca1)
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
cge04121
]
100770724 (Brca1)
03036 Chromosome and associated proteins [BR:
cge03036
]
100770724 (Brca1)
03400 DNA repair and recombination proteins [BR:
cge03400
]
100770724 (Brca1)
Enzymes [BR:
cge01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.27 RING-type E3 ubiquitin transferase
100770724 (Brca1)
Protein phosphatases and associated proteins [BR:
cge01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
100770724 (Brca1)
Ubiquitin system [BR:
cge04121
]
Ubiquitin ligases (E3)
Single Ring-finger type E3
Other single Ring-finger type E3
100770724 (Brca1)
Multi subunit type E3
BRCC complex
100770724 (Brca1)
Chromosome and associated proteins [BR:
cge03036
]
Eukaryotic type
Centrosome formation proteins
Centrosome duplication proteins
Regulators of centriole replication
100770724 (Brca1)
DNA repair and recombination proteins [BR:
cge03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
BRCA1-core complex
100770724 (Brca1)
BRCA1-A complex
100770724 (Brca1)
BRCA1-B complex
100770724 (Brca1)
BRCA1-C complex
100770724 (Brca1)
BRCA complex
100770724 (Brca1)
FA (Fanconi anemia) pathway
Downstream FA components
100770724 (Brca1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
BRCT_assoc
BRCT
zf-C3HC4
zf-C3HC4_2
BRCT_2
zf-RING_UBOX
zf-C3HC4_4
zf-RING_5
zf-RING_2
zf-C3HC4_3
RING_XB3-XBAT31
zf-ANAPC11
zf-Nse
zf-RING_6
zf-RING_10
Prok-RING_4
Prot_ATP_ID_OB_C
Motif
Other DBs
NCBI-GeneID:
100770724
NCBI-ProteinID:
XP_027283849
UniProt:
A0A8C2M647
LinkDB
All DBs
Position
7:complement(114526055..114593477)
Genome browser
AA seq
1813 aa
AA seq
DB search
MRALGWHKEKFCFVLFCSPYLEEMDLSAVQIEEVQNVLHAMQKILECPICLELIKEPIST
KCDHIFCKFCMLKLLNQKKGPSQCPLCKNEITKRSLQGSTRFSQLVEELLKITDAFELDT
GIQYANGYSISKLKNSSEPLNEEASIIQSVGYRNRGKRLRQIESGNATLKDSLSVQLSNL
GIVRSTKKNHQTQPRNKSVYIELESDSSEETVSKPDDCSVRDQELLQTTSLGAGDEVSLD
SSTRAACEFSEDVTNIDLHQCSNKDLDPIENHATGRYPEKCQDISVSNLHVEPCGTDIHA
SSLQHENSSLLLTEDRMNVEKAEFYNKSKQSGLARSQQNRWAESKETCNDRQIPSTEKKV
DPNTDSFCGRKKWKNQKSLCPENSRATQDVPWMTLNSSIQKVNEWFSKTGEMLTCDGTSD
RRHESNAGAAVVLEVSDEVDGCSSSSKEMDLVASDPHNALKCKSESDLSKPVENNIRDKI
FGKTYQRKGSLPHLNHVTEIIGTFIAEPQITQEHPFTNKLKRKRRTTCLHPEDFIKKADL
TVTQKTSKNVNQGTDQMEPDGLVMGITSNGQENETQGNNLQKEKNANPVKSLEKGSVSTT
KAKTISNSISDLELELNVHNSQAPKKSRLRRKSSTRCVLALEPVSRNPSPPACTEFQIDS
CSSSEETEKNNSNPTPVKNIRKPQLTEDTEPAADSKKNKEPNEQRRKRRASDPFPEEKFM
PGLLTNCPSSSKPQGPANPSPQRKEVEKLETSQMSDSTKDLRDLLLDGEQGLPTERSEES
TSVSLVPDTDYDTQNSVSLLEANAVRYAKTVSSQCMTQFVASDNPNELVHGSKDAGSGTE
CFKHPLRHELSHIQETIEMEESELDTQYLQNTFQASKRQSFTLFSKPRDPQEECVTACAS
SVSLRDMSPKVTSEGEQQEESRGHEEAEISHIQAGPATVGVPLPRQEGDPGADTMHAAVC
SLCPSSQYRSNENSHPKQSASPIMSSIKTGHGKTLSEEQSEKHTLSNEKAMGNETFVQST
MHTISQNHRKNGCQEANSGSINEVPSSGENFQGQLGRNRRTKLNTVLPLGLMQPGVCKHS
FPVSDYKYLEIKKQEGENVGAHFSSCLFSDKLEQPVGSGNVFQICSETPDDLLDDVEIQE
NTSFGEVDIMEKSAVFNGSVQRRELSRSPSPLTHASLARNLQRRSRKLESSEDSGSCEDE
DLPCFQHLLGQVSKTPEPSSVVTQPLSEKAEGTQVPWKSSVGDSDNEVILIEASQEHHPS
EDAKYSGSMFSSQPSAVQGSTANTSSQDPLFNLSKQKSHQSEDEEDFLSDKELISDDEEM
GTCLEEDNDQEEDIIIPDSAEAASGYESETNLSEDCSQSDILTTQQRATMKDNLIKLQQE
MAHLEAVLEQQGDQPSVHSSSLTAEPCAPEDLPNAEQNLSGTAILTSKNINENPVSRNPA
CVSADKFQPQPPDSSSSENKESREGRPSLFKSPLAGSRCSAHSRSGSLQNRNCPSQEELL
WTVEAGKSEGTPYLESGISLFSNRDPESESPKEPAYVCTTPASTSARTISQYQVSDSFES
PAATHAHTAVIETVSKKKPELTSSKGRANKGISMVVSGLTPKEVMIVQKFAEKYRLTLTD
AITEETTHVIMKTDAELVCERTLKYFLGIAGGKWIVSYSWVIQSIQERKLLSVHEFEVRG
DVVTGRNHQGPKRSRESQEKLFKGLTICCCEPFTNMPKDELEKMLQLCGASVVKELSSLT
PDTGVHPIVIVQPSAWTEENGCPEIDQLCGAHLVMWDWVLDSISVYRCRDLDAYLVQNIT
HGHDSSEPQDPND
NT seq
5442 nt
NT seq
+upstream
nt +downstream
nt
atgagggctctaggatggcataaagagaagttttgttttgttttgttttgttcaccatac
ctggaagaaatggatttatctgctgttcaaatcgaagaagtacaaaatgtccttcatgct
atgcagaaaatcctggagtgtccaatctgtttggaattgatcaaagaacccatttccaca
aagtgtgaccacatattttgcaaattttgtatgctgaaacttcttaaccagaagaaaggg
ccttcacaatgtcctttgtgtaagaatgagataaccaaaaggagcctgcaaggaagcacg
aggtttagtcagcttgttgaagagctgttgaaaatcactgatgcttttgagcttgacaca
ggaatacagtatgcaaacggttacagtatttcaaaattgaaaaattcttctgaacctttg
aatgaggaagcttccatcatccagagtgtgggctaccgaaaccgcggcaaaagacttaga
cagattgaatctggaaatgccaccttgaaggacagtctcagtgtccagctgtctaacctt
ggaattgtgagatcaacaaagaaaaatcatcagacacagcctcgaaataaatctgtgtac
attgaattagagtctgattcttctgaagagacagttagtaaaccagatgactgcagtgtg
agagaccaggaactgttacaaaccacctctctgggagctggagatgaagtcagtttggat
tcttcaaccagagctgcttgtgagttttctgaggacgtaacaaatattgatctgcaccag
tgcagtaataaagatttggaccccattgagaatcatgcaactggaagatatccagaaaaa
tgtcaggatatttctgtttcaaacttacatgtggagccatgtggcacagatattcatgcc
agctcgttacagcatgagaacagcagcttattactcactgaagacagaatgaatgtagaa
aaggctgagttctataataaaagcaaacagtctggcttagccaggagccaacagaacaga
tgggctgaaagtaaagaaacatgtaatgataggcagattcccagcactgagaaaaaggta
gatccaaatactgattccttctgtgggagaaaaaaatggaaaaatcagaaaagtctgtgt
cctgagaattctagagctacccaggatgttccttggatgacactgaatagcagcattcag
aaagtcaacgagtggttttccaaaactggtgaaatgctaacttgtgatggcacatctgac
aggaggcatgagtcaaatgctggagcagctgttgtgttagaagtttcagatgaagtagat
ggatgttccagttcttcaaaagaaatggacttagtggcctctgatccccataatgcttta
aagtgtaaaagtgaaagcgacctctccaaaccagtagagaacaatatccgagataaaata
tttgggaaaacgtatcagagaaagggaagtctccctcacttgaaccacgtaactgaaatt
ataggcacatttattgcagaaccacagataacacaagaacaccccttcacaaataaatta
aaacgtaaaaggagaactacatgccttcatcctgaggattttatcaagaaagcagattta
acagttactcaaaagacttctaaaaatgtaaatcaaggaactgaccaaatggagccagat
ggcctagtgatgggtattaccagtaatggtcaagagaatgaaacacaaggtaataatctt
cagaaagagaaaaatgctaatccagtgaagtccttggaaaaggggtctgtttccacaact
aaagccaaaactataagcaacagtataagtgatttggagctagaattaaatgtccacaat
tcacaggcacctaagaaaagtcggctgaggaggaagtcttcaaccagatgtgttcttgca
ctggaaccagtcagtaggaatccaagcccacctgcttgtactgaatttcaaattgatagt
tgtagcagcagtgaagaaacagagaaaaacaattccaacccaacaccagtcaagaacatt
agaaagcctcaactcacggaggacacagaacctgcagcagattccaagaagaataaagag
ccaaatgaacaaagaaggaagagaagggccagtgatcctttcccagaagagaaatttatg
cctggcttattaactaactgtccaagttctagtaaacctcaaggacctgccaatcctagc
cctcagagaaaggaagtagagaaacttgaaacaagccaaatgtctgacagtaccaaagac
ctgagggatctgttgctggatggagaacagggtttgcccactgagaggtcggaggagagt
accagtgtttcattggtgcctgacactgattatgacactcagaacagtgtgtcattgctg
gaagctaatgctgtcagatatgcaaaaacagtatcaagccagtgtatgacccagtttgta
gcaagtgataaccctaacgaactggtccatggttctaaagatgctggaagtggcacagag
tgcttcaagcatccattgagacacgaacttagccacattcaggagaccatagaaatggaa
gagagtgaacttgatactcagtatttacagaatacatttcaagcttcaaagcgtcagtca
tttactttattttcaaaaccaagagatccccaagaggagtgtgtaacagcttgtgcttcc
tctgtgtccttaagggacatgagtccaaaagtgacttctgaaggtgaacaacaagaagaa
agtcggggacacgaagaggctgaaatcagtcacatacaggcagggcctgcgacagtgggc
gtgcctctgcctcgtcaggaaggtgatccaggcgctgatacaatgcatgctgcagtgtgc
agcctttgtccatcatctcagtacagaagcaatgaaaactcacatcctaaacaatcagct
tctcccatcatgtcttctataaaaactggccatgggaaaaccctgtcagaggaacaatct
gagaaacatacattgtcaaatgaaaaggcaatgggaaatgagacctttgttcaaagcaca
atgcacacaattagccaaaaccacagaaaaaatggttgtcaagaagccaactcaggcagt
attaatgaagtgccttccagtggtgaaaacttccaaggacagctaggccgaaacagaagg
actaagttaaacactgtgcttccactaggtcttatgcaacctggagtctgtaagcatagt
tttcctgtcagtgattataaatatcttgaaataaaaaagcaggaaggtgagaatgttggt
gcacacttctcttcgtgtctgttttcagataagctcgaacaacctgtagggagtggtaat
gtttttcagatttgttctgagacacctgatgacctgttggatgatgttgaaatacaggaa
aatactagctttggtgaagttgacataatggagaagtctgctgtttttaacgggagtgtc
cagagacgagagctcagtaggagccctagccctttaacccatgcatcgctggctcggaat
ctccagagacggtctaggaagttagagtcctcagaagacagcggatcttgtgaggatgaa
gaccttccctgcttccaacacttacttggccaagtaagcaaaacacctgaacctagcagt
gttgtgacacagcctctgtcagagaaagcagaggggacccaagtgccatggaagagtagt
gttggtgactctgataacgaggtgatcttgatagaggcatctcaggaacatcaccctagt
gaggatgcaaaatactctggcagcatgttctcttctcagcccagtgctgtacaaggttca
actgcaaatacaagctcccaggaccccttgtttaacctttccaaacaaaagagtcaccag
tctgaggatgaggaagattttctaagtgacaaggaattgatttcagatgatgaggaaatg
ggaacttgcctagaagaagataatgatcaagaagaggatattataatcccagattcagct
gaagcggcatctggatatgagagtgaaacaaacctttctgaagattgctcacagagtgat
attttaaccactcagcagagggccaccatgaaggataacctgataaagctccagcaggag
atggcccacctggaggctgtgctagaacagcaaggggaccagccttctgtccactcctcg
tctctcacagctgaaccttgtgcccctgaagacctaccaaacgcagaacaaaacttatca
ggaacagcaattttaacttcaaagaatattaatgaaaatcctgtaagccggaatccagca
tgcgtttctgctgacaagttccaaccacaacctccagacagttccagcagtgaaaataaa
gagtcaagggaaggaaggccttccctttttaaatctccgttggcaggcagtaggtgctct
gcacacagccgctctgggagtcttcaaaacagaaactgcccatctcaagaggagctcctt
tggactgttgaagcagggaagtcagaaggaacgccatacctggaatctggaatcagcctt
ttctctaatagagaccctgaatctgagtcccctaaagagccagcttatgtttgcaccaca
ccagcttcaacctctgcacggacaatatcccagtatcaggtttctgactctttcgagagt
ccggctgctactcatgctcatactgcagtgatagaaactgtgagcaagaaaaagccagaa
ttgacatcttcaaaaggaagagccaataaaggaatatccatggtggtgtcaggcttgacc
cccaaagaagtaatgattgtgcaaaagtttgctgaaaaataccgcctcactttaactgat
gcaattactgaggagactacccatgtcattatgaaaacagatgctgagcttgtgtgtgaa
cggacactgaaatattttctgggaattgcaggaggaaaatggatagttagctattcatgg
gtgattcagtctattcaagaaagaaaacttctgagtgtgcatgaatttgaagtcagagga
gatgttgtgactggaagaaaccaccaaggtccaaagcgatccagagaatcccaggaaaag
ctcttcaaaggcctaacaatctgttgttgtgagcccttcaccaacatgcccaaagatgag
ctggagaagatgctgcagctgtgtggggcttccgtggtgaaggagctttcgtcactcacc
cctgacaccggtgttcatccaattgtgattgtacagccaagtgcctggacagaagagaat
ggctgccctgagattgaccagctgtgtggggcgcacctggtgatgtgggactgggtgttg
gacagtatatccgtctaccggtgtcgggatctggacgcctacctggtacagaatatcacc
catggccacgacagcagcgagccacaggaccccaatgattag
DBGET
integrated database retrieval system
