Entry Name ABC transporters - Corynebacterium hadale
Description The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class Environmental Information Processing; Membrane transportBRITE hierarchy
Pathway map Other DBs Organism Corynebacterium hadale [GN:
chad ]
Gene CHAD_01575 ecfT1; Energy-coupling factor transporter transmembrane protein EcfT [KO:K16785 ]
CHAD_01590 irtB1; Iron import ATP-binding/permease protein IrtB [KO:K14699 ] [EC:7.-.-.-]
CHAD_01595 irtA1; Iron import ATP-binding/permease protein IrtA [KO:K14698 ] [EC:7.-.-.-]
CHAD_01880 metI; D-methionine transport system permease protein MetI [KO:K02072 ]
CHAD_02270 phnV1; Putative 2-aminoethylphosphonate transport system permease protein PhnV [KO:K02011 ]
CHAD_04700 ecfT2; Energy-coupling factor transporter transmembrane protein EcfT [KO:K16785 ]
CHAD_05315 drrA2; Daunorubicin/doxorubicin resistance ATP-binding protein DrrA [KO:K20459 ]
CHAD_05570 phnV2; Putative 2-aminoethylphosphonate transport system permease protein PhnV [KO:K02011 ]
CHAD_07265 glnH2; ABC transporter glutamine-binding protein GlnH precursor [KO:K10005 ]
CHAD_07270 glnM; putative glutamine ABC transporter permease protein GlnM [KO:K10006 ]
CHAD_07275 gltK; Glutamate/aspartate transport system permease protein GltK [KO:K10007 ]
CHAD_07300 bioM; Biotin transport ATP-binding protein BioM [KO:K16784 ] [EC:7.6.2.-]
CHAD_07305 ecfT3; Energy-coupling factor transporter transmembrane protein EcfT [KO:K16783 ]
CHAD_08015 irtB2; Iron import ATP-binding/permease protein IrtB [KO:K14699 ] [EC:7.-.-.-]
CHAD_08020 irtA2; Iron import ATP-binding/permease protein IrtA [KO:K14698 ] [EC:7.-.-.-]
CHAD_11315 ecfT4; Energy-coupling factor transporter transmembrane protein EcfT [KO:K16785 ]
CHAD_11325 irtB3; Iron import ATP-binding/permease protein IrtB [KO:K14699 ] [EC:7.-.-.-]
CHAD_11330 irtA3; Iron import ATP-binding/permease protein IrtA [KO:K14698 ] [EC:7.-.-.-]
CHAD_11550 yusV2; putative siderophore transport system ATP-binding protein YusV [KO:K23188 ]
CHAD_11555 fepG; Ferric enterobactin transport system permease protein FepG [KO:K23187 ]
CHAD_11560 yfiZ; putative siderophore transport system permease protein YfiZ precursor [KO:K23186 ]
CHAD_11705 ugpB; sn-glycerol-3-phosphate-binding periplasmic protein UgpB precursor [KO:K05813 ]
CHAD_11715 ugpA; sn-glycerol-3-phosphate transport system permease protein UgpA [KO:K05814 ]
CHAD_12010 ytrE3; ABC transporter ATP-binding protein YtrE [KO:K09814 ] [EC:7.6.2.-]
CHAD_12475 ugpC; sn-glycerol-3-phosphate import ATP-binding protein UgpC [KO:K10112 ] [EC:7.5.2.-]
Compound C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference Authors Tomii K, Kanehisa M.
Title A comparative analysis of ABC transporters in complete microbial genomes.
Journal Reference Authors Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal Reference Authors Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal Reference Authors Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal Reference Authors Quintero MJ, Montesinos ML, Herrero A, Flores E
Title Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal Reference Authors Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal Reference Authors Valladares A, Montesinos ML, Herrero A, Flores E.
Title An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal Reference Authors Richard-Fogal CL, Frawley ER, Kranz RG
Title Topology and function of CcmD in cytochrome c maturation.
Journal Reference Authors Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal Reference Authors Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal Reference Authors Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal Reference Authors Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal KO pathway
