Capra hircus (goat): 102168375
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Entry
102168375 CDS
T02910
Symbol
HSD11B1
Name
(RefSeq) corticosteroid 11-beta-dehydrogenase isozyme 1 isoform X1
KO
K15680
corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:
1.1.1.146
]
Organism
chx
Capra hircus (goat)
Pathway
chx00140
Steroid hormone biosynthesis
chx00980
Metabolism of xenobiotics by cytochrome P450
chx01100
Metabolic pathways
chx05204
Chemical carcinogenesis - DNA adducts
Module
chx_M00109
C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:
chx00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
102168375 (HSD11B1)
09111 Xenobiotics biodegradation and metabolism
00980 Metabolism of xenobiotics by cytochrome P450
102168375 (HSD11B1)
09160 Human Diseases
09161 Cancer: overview
05204 Chemical carcinogenesis - DNA adducts
102168375 (HSD11B1)
Enzymes [BR:
chx01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.146 11beta-hydroxysteroid dehydrogenase
102168375 (HSD11B1)
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GFIT
Motif
Pfam:
adh_short
adh_short_C2
KR
DUF1776
THF_DHG_CYH_C
2-Hacid_dh_C
Pyr_redox_2
Shikimate_DH
Pyr_redox_3
NAD_binding_2
Methyltransf_25
FMO-like
ADH_zinc_N
Pyr_redox
Motif
Other DBs
NCBI-GeneID:
102168375
NCBI-ProteinID:
XP_005691100
UniProt:
A0A452FGI3
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Position
16:complement(72192175..72232663)
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AA seq
292 aa
AA seq
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MAFMKKYLLPILGIFLAYYYYSANEEFRPEMLRGKRVIVTGASKGIGREMAYHLARMGAH
VVVTARSEESLKKVVSRCLELGAASAHYVAGTMENMTFAEQFVAKAGELVGGLDMLILNH
INYTPLRVFSNDIHLLRRSLEVNLLSYVVLSTAALPMLKQTNGSIVVVSSVAGKIACPLA
AAYSASKFALDGFFSSLRTEYEATKVNVSITLCILGLIDTDTAMKAVAGIYNAEASPKEE
CALEIIKGGALRQDEVYYDNSILTSLLLKNPGRKIMEFLSLKKYNMERFINN
NT seq
879 nt
NT seq
+upstream
nt +downstream
nt
atggcttttatgaaaaaatacctcctccccattctggggatcttcttggcctactactac
tattctgcgaatgaggaattcagaccagagatgcttcgaggaaagagagtgattgtcacg
ggggccagcaagggaatcggaagagaaatggcctatcacctggcaaggatgggagctcac
gtggtagtgacagcgaggtcagaagaaagtctaaagaaggtggtatcccgctgcctggag
ctgggggcggcctcagcgcactacgtggcaggcaccatggagaacatgaccttcgcagaa
caatttgttgccaaagctggagagctcgtggggggacttgacatgctcattctcaaccac
atcaactatacgcctttgagggtgtttagcaatgacattcatctcttgcgcagaagccta
gaggtcaacctcctgagttacgtggtcctgagcacggctgccttgcccatgctgaagcag
accaacgggagtattgtggtcgtctcctccgtagccgggaaaatagcttgtccacttgct
gctgcctattctgcaagcaagtttgctctggatgggttcttctcctctctcaggacggaa
tatgaggcgaccaaggtcaatgtgtccatcaccctctgtattcttggcctcatcgacaca
gacacagccatgaaggcagttgctgggatatacaatgcagaagcatctccaaaggaagaa
tgtgccctggagattatcaaagggggagctctgcgccaagatgaagtttattatgacaat
tcaatcttgacttctctcctgctgaaaaatccaggaaggaagatcatggaatttctctcc
ttgaagaaatataatatggaaagatttataaacaactag
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