Capra hircus (goat): 102171746 Help Entry 102171746         CDS       T02910                                  Symbol LCK Name (RefSeq) tyrosine-protein kinase Lck   KO K05856   lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2] Organism chx  Capra hircus (goat) Pathway chx04064   NF-kappa B signaling pathway chx04380   Osteoclast differentiation chx04650   Natural killer cell mediated cytotoxicity chx04658   Th1 and Th2 cell differentiation chx04659   Th17 cell differentiation chx04660   T cell receptor signaling pathway chx05135   Yersinia infection chx05166   Human T-cell leukemia virus 1 infection chx05235   PD-L1 expression and PD-1 checkpoint pathway in cancer chx05340   Primary immunodeficiency Brite KEGG Orthology (KO) [BR:chx00001]  09130 Environmental Information Processing   09132 Signal transduction    04064 NF-kappa B signaling pathway     102171746 (LCK)  09150 Organismal Systems   09151 Immune system    04650 Natural killer cell mediated cytotoxicity     102171746 (LCK)    04660 T cell receptor signaling pathway     102171746 (LCK)    04658 Th1 and Th2 cell differentiation     102171746 (LCK)    04659 Th17 cell differentiation     102171746 (LCK)   09158 Development and regeneration    04380 Osteoclast differentiation     102171746 (LCK)  09160 Human Diseases   09161 Cancer: overview    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     102171746 (LCK)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     102171746 (LCK)   09171 Infectious disease: bacterial    05135 Yersinia infection     102171746 (LCK)   09163 Immune disease    05340 Primary immunodeficiency     102171746 (LCK)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:chx01001]     102171746 (LCK)   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:chx03036]     102171746 (LCK) Enzymes [BR:chx01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      102171746 (LCK) Protein kinases [BR:chx01001]  Non-receptor tyrosine kinases   SRC family    102171746 (LCK) Chromosome and associated proteins [BR:chx03036]  Eukaryotic type   Centrosome formation proteins    Kinases and associated factors     102171746 (LCK) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase SH2 SH3_1 SH3_2 SH3_9 ABC1 SH2_1 Haspin_kinase Kdo Motif Other DBs NCBI-GeneID:  102171746 NCBI-ProteinID:  XP_017913242 UniProt:  A0A452EIH9 LinkDB All DBs Position 2:14417074..14437371 Genome browser AA seq 509 aa AA seqDB search MGCSCSSNPEDDWMENIDVCENCHYPIVPLDGKTTLPMRNGSEVRDPLVTYEGSNPPASP LQDNLVIALHSYVPSHDGDLGFEKDEQLRILEQNGEWWKAQSLTTGQEGFIPFNFVAKAN SLEPEPWFFKTLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQTQGEVVKH YKIRNLDKGGFYISPRVTFPGLHELVRHYMNTSDGLCTRLSRPCQTQKPQKPWWEDEWEV PRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRL VRLYAVVTQEPIYIITEYMENGSLVDFLKTSEGIKLTINKLLDMAAQIAEGMAFIEERNY IHRDLRAANILVSHSLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIK SDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMMLCWKER PEDRPTFDYLRSVLEDFFTATEGQYQPQP NT seq 1530 nt NT seq  +upstreamnt  +downstreamnt atgggctgtagctgcagctcaaacccagaagatgactggatggaaaacatcgatgtttgt gaaaactgccactaccccatagtcccactggatggcaagaccacgctgcccatgcggaat ggctctgaagtgcgtgatccactggtcacctacgagggatccaaccccccagcttctcca ctgcaagacaacctggttatcgccctgcacagctatgtgccttctcacgacggagacctg ggcttcgagaaggatgaacagctccgtatcctggagcagaacggcgagtggtggaaggcg cagtccctgaccaccggccaggaaggtttcatccccttcaacttcgtggccaaagcgaac agcctggagcccgaaccctggttcttcaagaccctgagccgcaaggacgctgagaggcag ctcctggcgccggggaacacgcacggctctttcctgatccgggagagcgagagcactgcg ggatcgttttcactgtcggtccgggacttcgaccagacccagggagaagtggtgaaacat tacaagatccggaacctggacaaaggcggcttctacatctcgccccgcgtcacttttccc ggcttgcacgagctggtccgccattacatgaatacttcggacgggctgtgcacacggttg agccgcccctgccagacccagaagccccagaagccgtggtgggaggatgagtgggaggtt cccagggagactctgaagctggtggagcggctgggggctggccagttcggagaggtgtgg atggggtactacaacgggcacacgaaggtggcagtcaagagcctgaagcagggcagcatg tcccccgatgccttcctggccgaggccaacctcatgaagcagctgcaacaccagcggctg gtccggctctacgcggtggtcacccaggagccaatctacatcatcacggaatatatggag aacggaagcctggtggattttctcaagacctccgaaggcatcaagctgactatcaacaaa ctcttggacatggcagcccaaattgcagagggtatggcattcattgaagagcggaattat atccaccgtgacttgagggctgccaacatcctggtgtcccatagcctgagctgcaagatc gcagactttggtctagcacgcctcattgaggacaacgagtacacagccagggagggtgcc aagtttcccattaagtggacagcaccagaagccattaactatgggacattcaccatcaag tcggacgtgtggtctttcgggatcctgctgacggagattgtcactcatggtcgcatccct tacccagggatgaccaatcctgaggtgattcagaacctggagcgaggctaccgcatggta cgacctgacaactgcccggaggagttgtaccagcttatgatgctgtgctggaaggagcgc ccggaggaccggcccacctttgactacctgcgcagcgtgttggaggacttcttcacggcc acggagggccagtaccaaccccaaccctga

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