Capra hircus (goat): 102171922 Help Entry 102171922         CDS       T02910                                  Symbol ADCY2 Name (RefSeq) adenylate cyclase type 2   KO K08042   adenylate cyclase 2 [EC:4.6.1.1] Organism chx  Capra hircus (goat) Pathway chx00230   Purine metabolism chx01100   Metabolic pathways chx01522   Endocrine resistance chx04015   Rap1 signaling pathway chx04020   Calcium signaling pathway chx04022   cGMP-PKG signaling pathway chx04024   cAMP signaling pathway chx04062   Chemokine signaling pathway chx04072   Phospholipase D signaling pathway chx04081   Hormone signaling chx04082   Neuroactive ligand signaling chx04114   Oocyte meiosis chx04211   Longevity regulating pathway chx04213   Longevity regulating pathway - multiple species chx04261   Adrenergic signaling in cardiomyocytes chx04270   Vascular smooth muscle contraction chx04371   Apelin signaling pathway chx04540   Gap junction chx04611   Platelet activation chx04713   Circadian entrainment chx04714   Thermogenesis chx04723   Retrograde endocannabinoid signaling chx04724   Glutamatergic synapse chx04725   Cholinergic synapse chx04727   GABAergic synapse chx04750   Inflammatory mediator regulation of TRP channels chx04911   Insulin secretion chx04912   GnRH signaling pathway chx04913   Ovarian steroidogenesis chx04914   Progesterone-mediated oocyte maturation chx04915   Estrogen signaling pathway chx04916   Melanogenesis chx04918   Thyroid hormone synthesis chx04921   Oxytocin signaling pathway chx04922   Glucagon signaling pathway chx04923   Regulation of lipolysis in adipocytes chx04925   Aldosterone synthesis and secretion chx04926   Relaxin signaling pathway chx04927   Cortisol synthesis and secretion chx04928   Parathyroid hormone synthesis, secretion and action chx04934   Cushing syndrome chx04935   Growth hormone synthesis, secretion and action chx04970   Salivary secretion chx04971   Gastric acid secretion chx04972   Pancreatic secretion chx04976   Bile secretion chx05032   Morphine addiction chx05163   Human cytomegalovirus infection chx05166   Human T-cell leukemia virus 1 infection chx05200   Pathways in cancer chx05207   Chemical carcinogenesis - receptor activation chx05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:chx00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     102171922 (ADCY2)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     102171922 (ADCY2)    04371 Apelin signaling pathway     102171922 (ADCY2)    04020 Calcium signaling pathway     102171922 (ADCY2)    04072 Phospholipase D signaling pathway     102171922 (ADCY2)    04024 cAMP signaling pathway     102171922 (ADCY2)    04022 cGMP-PKG signaling pathway     102171922 (ADCY2)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     102171922 (ADCY2)    04081 Hormone signaling     102171922 (ADCY2)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     102171922 (ADCY2)   09144 Cellular community - eukaryotes    04540 Gap junction     102171922 (ADCY2)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     102171922 (ADCY2)    04062 Chemokine signaling pathway     102171922 (ADCY2)   09152 Endocrine system    04911 Insulin secretion     102171922 (ADCY2)    04922 Glucagon signaling pathway     102171922 (ADCY2)    04923 Regulation of lipolysis in adipocytes     102171922 (ADCY2)    04912 GnRH signaling pathway     102171922 (ADCY2)    04913 Ovarian steroidogenesis     102171922 (ADCY2)    04915 Estrogen signaling pathway     102171922 (ADCY2)    04914 Progesterone-mediated oocyte maturation     102171922 (ADCY2)    04921 Oxytocin signaling pathway     102171922 (ADCY2)    04926 Relaxin signaling pathway     102171922 (ADCY2)    04935 Growth hormone synthesis, secretion and action     102171922 (ADCY2)    04918 Thyroid hormone synthesis     102171922 (ADCY2)    04928 Parathyroid hormone synthesis, secretion and action     102171922 (ADCY2)    04916 Melanogenesis     102171922 (ADCY2)    04925 Aldosterone synthesis and secretion     102171922 (ADCY2)    04927 Cortisol synthesis and secretion     102171922 (ADCY2)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     102171922 (ADCY2)    04270 Vascular smooth muscle contraction     102171922 (ADCY2)   09154 Digestive system    04970 Salivary secretion     102171922 (ADCY2)    04971 Gastric acid secretion     102171922 (ADCY2)    04972 Pancreatic secretion     102171922 (ADCY2)    04976 Bile secretion     102171922 (ADCY2)   09156 Nervous system    04724 Glutamatergic synapse     102171922 (ADCY2)    04727 GABAergic synapse     102171922 (ADCY2)    04725 Cholinergic synapse     102171922 (ADCY2)    04723 Retrograde endocannabinoid signaling     102171922 (ADCY2)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     102171922 (ADCY2)   09149 Aging    04211 Longevity regulating pathway     102171922 (ADCY2)    04213 Longevity regulating pathway - multiple species     102171922 (ADCY2)   09159 Environmental adaptation    04713 Circadian entrainment     102171922 (ADCY2)    04714 Thermogenesis     102171922 (ADCY2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102171922 (ADCY2)    05207 Chemical carcinogenesis - receptor activation     102171922 (ADCY2)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     102171922 (ADCY2)    05163 Human cytomegalovirus infection     102171922 (ADCY2)   09165 Substance dependence    05032 Morphine addiction     102171922 (ADCY2)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     102171922 (ADCY2)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     102171922 (ADCY2)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     102171922 (ADCY2) Enzymes [BR:chx01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      102171922 (ADCY2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Guanylate_cyc Adcy_cons_dom AC_N HNOBA Motif Other DBs NCBI-GeneID:  102171922 NCBI-ProteinID:  XP_017921111 UniProt:  A0A452FU52 LinkDB All DBs Position 20:complement(65363733..65826082) Genome browser AA seq 1091 aa AA seqDB search MWQEAMRRRRYLRDRAEAAAGGGDGLQRSRDWLYESYYRMSQQHPLIVFLLLIVMGACLA LLAVFFALRLEVEDHVAFLITVPTALAIFFAIFILVCIESVFKKLLRLFSLVIWICLVAM GYLFMCFGGTVSPWDQVSFFLFIIFVVYTMLPFNMRDAIIASVLTSSSHTIVLSVCLSAT PGAKQHLVWQILANVIIFICGNLAGAYHKHLMELALQQTYQDTCNCIKSRIKLEFEKRQQ ERLLLSLLPAHIAMEMKAEIIQRLQGPKAGQMENTNNFHNLYVKRHTNVSILYADIVGFT RLASDCSPGELVHMLNELFGKFDQIAKENECMRIKILGDCYYCVSGLPISLPNHAKNCVK MGLDMCEAIKKVRDATGVDINMRVGVHSGNVLCGVIGLQKWQYDVWSHDVTLANHMEAGG VPGRVHISSVTLQHLNGAYKVEEGDGDVRDPYLKQHLVKTYFVINPKGERRSPQHLFRPR HTLDGAKMRASVRMTRYLESWGAAKPFAHLHHRDSMTTENGKISTTDVPMGQHNFQNRTL RTKSQKKRFEEELNERMIQAIDGINAQKQWIKSEDIQRISLLFYNKILEKEYRATALPAF KYYVTCACLIFFGIFIVQVLVLPKTSILGISFGAAFLSLALILFVCFAGQLLQCSKKASA SLLWLLKSSGIIANRPWPRISLTVITTAIILTMAVFNMFFLSDSEETILPTANASNTSLS GTSNQAAILRAQNLFFLPYFIYSCILGLISCSVFLRVNYELKMLIMMVALVGYNTIFLHT HAPLLDDYSQVLFERPGIWKDLKTMGSVSLFIFFITLLVLGRQNEYYCRLDFLWKNKFKK EREEIETMENLNRVLLENVLPAHVAEHFLARSLKNEDLYHQSYDCVCVMFASIPDFKEFY TESDVNKEGLECLRLLNEIIADFDDLLSKPKFSGVEKIKTIGSTYMAATGLSAVPSQEHA QEPERQYMHIGTMVEFAFALVGKLDAINKHSFNDFKLRVGINHGPVIAGVIGAQKPQYDI WGNTVNVASRMDSTGVLDKIQVTEETSIILQTLGYTCTCRGIINVKGKGDLKTYFVNTEM SRSLSQSNLTS NT seq 3276 nt NT seq  +upstreamnt  +downstreamnt atgtggcaggaggcgatgcggcggcgccgctacctgcgggaccgcgccgaggcggcggcg ggcggcggagacgggctgcagcggtcccgggactggctctacgaatcctactaccgcatg agccagcagcacccgctcatcgtcttcctgctgctcatcgtcatgggcgcctgcctcgcc ctgctcgccgtcttcttcgcgctccgcctggaagttgaagaccacgtggcatttttaatc acagttccgactgccctggcgattttctttgcgatcttcatcctggtgtgcatcgagtcg gtgtttaagaagctgctgcgcctcttctctttggtgatatggatctgtctcgtggccatg ggctacttgttcatgtgttttgggggcaccgtctctccctgggaccaggtgtcgttcttc ctcttcatcatcttcgtggtgtacaccatgctgcccttcaacatgcgagatgccatcatc gccagcgtcctcacctcctcttctcacaccatcgtgctgagcgtctgcctgtctgcgacc ccaggggccaagcagcacctggtctggcagatcctggccaacgtgatcatcttcatctgc gggaacctggcgggggcgtaccataagcacctcatggagctcgctctgcagcagacgtat caggacacgtgcaactgcatcaagtcccggatcaagctggaatttgaaaaacgtcagcag gagcggctgctgctctccttgctgccggcacacatagccatggagatgaaagcggagatc atccagaggctgcagggccccaaagccggccagatggagaacaccaacaacttccacaac ctctacgtcaagcggcacaccaacgtcagtatcctctatgcggacattgttgggttcacc cgtctggccagtgactgctcccctggagagctcgtccacatgctgaatgaactctttgga aagttcgatcaaattgcaaaggagaatgaatgcatgagaataaaaattttaggggactgc tactactgtgtgtccggactgcccatatctctccctaaccatgccaagaattgtgtgaaa atgggactggatatgtgtgaagccataaagaaagtgcgggacgccaccggagtggacatc aacatgcgcgtgggagtgcattctgggaacgtcctgtgcggcgtgatcgggctgcagaag tggcagtacgacgtgtggtcacatgacgtcaccctggccaaccacatggaagctggaggg gtccctggacgtgttcacatctcttctgttaccctgcaacacttgaatggagcttacaaa gtggaagaaggcgatggtgacgtcagagacccgtatttaaagcaacacttggtgaaaact tactttgtaatcaaccccaagggagagcggcggagccctcaacacctcttcaggccccga cacacccttgacggagcgaagatgagggcttctgtccgcatgacccggtacctggagtcc tggggggcggccaagccctttgcacacctgcatcatagagacagcatgactacggagaac ggcaagatcagcaccacggatgtaccaatgggtcagcataattttcaaaaccgcacctta agaacgaagtcacaaaagaaaagatttgaagaggaattaaatgaaaggatgattcaagca attgatggaatcaatgcacagaagcaatggatcaagtccgaagacattcagagaatctca ttgcttttctacaataaaatactagaaaaagaataccgagccaccgcactgccggccttc aagtattacgtgacttgcgcttgcctcatcttcttcggcatctttatcgtgcaggttctg gtcttacccaaaacgtccattctcgggatttcctttggagcggcgtttctctcacttgcc cttatccttttcgtctgctttgctggacagcttttgcaatgcagcaagaaagcatctgct tctctcctgtggcttttaaagtcatcgggcatcatcgccaaccggccttggcctcggatc tccctgacggtcatcaccacagccatcatattgaccatggccgtgttcaatatgtttttc ctgagtgactcagaggaaacaattcttccgactgccaacgcgtccaacacgagtctttct ggcacaagtaaccaggcagcgattctgcgtgcgcaaaatttgtttttcctgccgtacttt atatacagctgcatcctcgggctgatctcctgttctgtcttcctgcgtgtgaattatgag ctgaagatgctgatcatgatggtagccttggtgggctacaacaccatcttcctccacact cacgctcccctcctggacgactacagccaggtcctgttcgagagaccaggcatttggaaa gacctaaagaccatgggctcagtatctctctttatatttttcatcacactgcttgttctg ggcagacagaatgaatattactgtaggttagacttcttatggaagaacaagttcaaaaaa gagcgggaggagatagaaaccatggagaacttgaaccgagtgctgctggagaatgtgctt cctgcgcacgtggctgagcacttcctggcccggagcctgaaaaacgaggatttataccac cagtcctatgactgcgtctgcgtcatgtttgcctccattcctgacttcaaagagttctat acggagtccgacgtgaacaaggagggtttggaatgccttcggctcctgaacgaaatcatt gccgactttgatgatctgctatccaagccgaagttcagtggcgttgaaaagatcaagacc atcggcagcacgtacatggcagcgacgggtctgagcgcggtgcccagccaggagcacgcc caggagcccgagaggcagtacatgcacattggcaccatggtggagtttgcgtttgccctg gtggggaagctggacgccatcaacaagcactccttcaatgacttcaagttacgagtaggt attaaccatggccctgtcatagccggtgtgattggagctcagaagccgcagtatgacatc tggggcaacaccgtcaatgtggccagcaggatggacagcaccggagtcctggacaaaatc caggtgacagaggagacgagcatcatcctacagaccctgggctacacgtgcacgtgtcgg ggaatcatcaacgtgaaaggaaagggagacctgaagacctacttcgtcaacacggagatg tcacggtccctttctcagagcaacctgacctcctga

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