Capra hircus (goat): 102184858 Help Entry 102184858         CDS       T02910                                  Symbol IRS1 Name (RefSeq) insulin receptor substrate 1   KO K16172   insulin receptor substrate 1 Organism chx  Capra hircus (goat) Pathway chx04022   cGMP-PKG signaling pathway chx04068   FoxO signaling pathway chx04081   Hormone signaling chx04140   Autophagy - animal chx04150   mTOR signaling pathway chx04151   PI3K-Akt signaling pathway chx04152   AMPK signaling pathway chx04211   Longevity regulating pathway chx04213   Longevity regulating pathway - multiple species chx04722   Neurotrophin signaling pathway chx04910   Insulin signaling pathway chx04920   Adipocytokine signaling pathway chx04923   Regulation of lipolysis in adipocytes chx04930   Type II diabetes mellitus chx04931   Insulin resistance chx04932   Non-alcoholic fatty liver disease chx04935   Growth hormone synthesis, secretion and action chx04960   Aldosterone-regulated sodium reabsorption chx05010   Alzheimer disease chx05206   MicroRNAs in cancer chx05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:chx00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     102184858 (IRS1)    04022 cGMP-PKG signaling pathway     102184858 (IRS1)    04151 PI3K-Akt signaling pathway     102184858 (IRS1)    04152 AMPK signaling pathway     102184858 (IRS1)    04150 mTOR signaling pathway     102184858 (IRS1)   09133 Signaling molecules and interaction    04081 Hormone signaling     102184858 (IRS1)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     102184858 (IRS1)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     102184858 (IRS1)    04923 Regulation of lipolysis in adipocytes     102184858 (IRS1)    04920 Adipocytokine signaling pathway     102184858 (IRS1)    04935 Growth hormone synthesis, secretion and action     102184858 (IRS1)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     102184858 (IRS1)   09156 Nervous system    04722 Neurotrophin signaling pathway     102184858 (IRS1)   09149 Aging    04211 Longevity regulating pathway     102184858 (IRS1)    04213 Longevity regulating pathway - multiple species     102184858 (IRS1)  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     102184858 (IRS1)   09164 Neurodegenerative disease    05010 Alzheimer disease     102184858 (IRS1)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     102184858 (IRS1)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     102184858 (IRS1)    04932 Non-alcoholic fatty liver disease     102184858 (IRS1)    04931 Insulin resistance     102184858 (IRS1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  IRS PH PH_11 Motif Other DBs NCBI-GeneID:  102184858 NCBI-ProteinID:  XP_017914353 LinkDB All DBs Position 2:20731947..20796443 Genome browser AA seq 1235 aa AA seqDB search MASPPETDGFSDVRKVGYLRKPKSMHKRFFVLRAASEAGGPARLEYYENEKKWRHKSSAP KRSIPLESCFNINKRADSKNKHLVALYTRDEHFAIAADSEAEQDSWYQALLQLHNRAKGH HDGAAAPGAGGGGGSCSGSSGLGEAGEDLSYGDVPPGPAFKEVWQVILKPKGLGQTKNLI GIYRLCLTSKTISFVKLNSEAAAVVLQLMNIRRCGHSENFFFIEVGRSAVTGPGEFWMQV DDSVVAQNMHETILEAMRAMSDEFRPRSKSQSSSNCSNPISVPLRRHHLNNPPPSQVGLT RRSRTESITATSPASLVGGKQGSFRVRASSDGEGTMSRPASVDGSPVSPSTNRTHAHRHR GSSRLHPPLNHSRSIPMPSSRCSPSATSPVSLSSSSTSGHGSTSDCLFPRRSSASVSGSP SDGGFISSDEYGSSPCDFRSSFRSVTPDSLGHTPPARGEEELSNYICMGGKGASTLTAPN GHYILPRGGNGHRYVPAAGLGTSPALPGEEAAGAADLDNRFRKRTHSAGTSPTISHQKTP SQSSVASIEEYTEMMPAYPPGGGSGGRVPSYRHSAFVPTHSYPEEGLEMHPLERRVGHHR PDTSSLHTDDGYMPMSPGVAPVPGSRKGSGDYMPMSPKSVSAPQQIINPIRRHPQRVDPN GYMMMSPSGSCSPDIGGGPSSGGSSSGAAPSGSSYGKLWTNGVGGHHSHPLPHPKLPVES GSGKLLSCTGDYMNMSPVGDSNTSSPSDCYYGPEDPQHKPVLSYYSLPRSFKHTQRPGEL EEPRHHQHLRLSSSSGRLLYAAAAEDSSSSTSSDSLGGGYCGARPEPGLPHLHHQVLQAH LPRKVDTAAQTNNRLARPTRLSLGDPKASTLPRAREQQQPPPLLLPPEPKSPGEYVNIEF GSDQPGYLSGPVASHSSPSIRCPSQLQPAPREEETGAEEYMNMDLGPGRRATWQESVGVQ PGRVGPAPPGAASVCRPTRAVPSSRGDYMTMQMGGPRQSYVDTSPVAPISYADMRTGVVE DASLPGATADAPSSSSTASVSSTAPPGTGELAARSALLGGPSAFTRVNLSPNRNQSAKVI RADPQGCRRRHSSETFSSTPSATRVGNTVPFGAGAAVAGSGGGSSSSAEDVKRHSSASFE NVWLRPGELGGAPKELAQLCGAAGGLENGLNYIDLDLVKDFKQRPQERPPQPQPPPLPAP HQPLGSSQSGPTSRSSEDLSAYASITFQKQPEDLQ NT seq 3708 nt NT seq  +upstreamnt  +downstreamnt atggcgagccctccggagacggacggcttctcggacgtgcgcaaggtgggctacctgcgc aaacccaagagcatgcacaagcgattcttcgtgctgcgggcggccagcgaggctgggggt ccggcgcgcctcgagtactacgagaacgaaaagaagtggcggcacaagtcgagcgccccc aaacgctcgatccccctggagagctgcttcaacatcaacaagcgggcggactccaagaac aagcacctggtggccctctacacccgggacgagcactttgccatcgcggcagacagcgag gccgagcaggacagctggtaccaggccctcctgcagctgcacaaccgtgccaagggccac cacgacggggccgcggcgcctggggcgggaggcggcgggggcagctgcagtggcagctcc ggcctcggggaggccggggaggacttgagctacggggacgtgcccccaggacccgccttc aaggaggtctggcaggtgatcctgaaacccaagggcttgggtcagacaaagaacctgatt ggcatctaccgcctctgcctgaccagcaagaccatcagcttcgtgaagctgaactcggag gcggcggccgtggtgctgcagttgatgaacatcaggcgctgtggccactcagagaacttc ttcttcatcgaagtgggccgttccgcagtgacgggcccgggggagttctggatgcaggtg gatgactccgtggtggcccagaacatgcatgagacaatcctggaggccatgcgggccatg agcgatgagttccgccctagaagcaagagccagtcctcctccaactgctccaaccccatt agtgtgcccctcaggaggcaccacctcaacaaccctccacccagccaggtggggctgacc cgccgctcgcgcaccgagagcatcacggccacctccccagccagcttggtgggcgggaag cagggctccttccgcgtgcgtgcctccagtgatggcgaaggcaccatgtctcgccctgcc tcagtggacggcagtcctgtgagtcctagcaccaacaggacccacgcccaccgccatcga ggcagctcccggctgcacccgcctctcaatcacagccgctccatccccatgccttcttct cgctgctcgccttccgccaccagccccgtcagtctgtcgtccagcagcacgagtggccac ggctccacctcagactgccttttcccgcggcggtctagtgcttctgtgtctggttccccc agtgatggcggcttcatctcctccgatgagtatggctccagtccctgcgatttccgaagc tccttccgcagcgtcaccccagattccctgggccacaccccgcccgcccggggtgaggaa gagctgagcaactacatctgcatgggaggcaagggggcctccaccctcactgcccccaat ggtcactacattttgccccggggtggcaatggtcaccgctacgtgccagccgcaggcttg ggcacgagcccagccctgccaggagaagaagcagccggtgcggcagatctggataatcgg ttccgaaagcggactcattctgcgggcacctcgcctaccatttcccaccagaaaacccca tctcagtcctctgtggcttccattgaggaatatactgaaatgatgcccgcctacccacca ggaggtggcagtggaggccgagtacccagctaccggcactctgccttcgtgcccacccac tcctacccagaggagggtctggaaatgcaccccttggagcggcgtgtgggccaccaccgc ccagacacctccagccttcacaccgatgatggctacatgcccatgtccccaggggtggcc ccagtgcccggcagccggaaaggcagtggggactacatgcccatgagccctaagagcgtg tctgccccacagcagatcatcaaccccattagacgtcatccccagagagtggaccccaac ggctacatgatgatgtccccaagcggcagctgctctcctgacattggaggtgggcccagc agcggcggcagcagcagcggcgccgccccttctgggagcagctatggcaagctctggaca aacggggtagggggccaccactctcaccccctgccacaccccaaacttccggtggagagc ggtagtggcaaactcctgtcttgtacaggtgactacatgaacatgtcgcccgttggggac tccaacaccagcagcccctccgactgctattatggccccgaggacccccagcacaagccc gtcctctcctactactcattgccaaggtccttcaagcatacccagcgccctggggagctg gaggagccccggcaccaccagcacctccgcctttcctcaagttccggtcgactcctctac gctgcggccgcagaagattcctcttcgtccaccagcagcgacagcctgggcgggggatac tgtggggctcggccagagcctggcctcccacatctccatcatcaggtccttcaggcccat ctgcctcgaaaggtggacacagctgcccagaccaacaaccgcctggctcggcccacgagg ctgtctctgggggatcccaaggccagcactttacctcgggcccgagagcagcagcagccg cccccgttgctgctccctccggagcctaagagcccaggggagtatgtgaatattgaattt gggagcgatcagccaggctacttatcaggcccggtggcgtcccacagctcgccttccatc aggtgtccgtcccagctccagccagctcccagagaggaggaaacgggcgcagaagagtat atgaacatggacctggggccgggccggagggccacctggcaggagagcgtgggggtccag ccgggcagggtgggcccggcgccccctggagctgctagcgtgtgcaggccgactagggca gtgcccagcagccgcggcgactatatgaccatgcagatgggcggtccccggcagagctac gtggacacctcacctgtcgcgcccatcagctacgccgacatgcggacgggtgtcgtggag gatgccagcctgcccggggccaccgcggacgctccctcctcatcctccacggcctctgtt tcctccactgcacctccgggaacaggggagctggcggcccgctcggccctgctggggggc ccgagcgccttcacgcgggtgaacctcagtcccaaccgcaaccagagtgccaaagtgatc cgtgccgacccgcaagggtgcaggaggcggcacagctccgagaccttctcctctacgccc agtgccacacgggtgggtaacacggtgcccttcggagccggggctgccgtcgcgggcagc ggtggcggcagcagcagcagcgccgaggatgtcaaacgccacagctctgcttccttcgag aacgtgtggctgaggcctggggagcttgggggagcccccaaggagctggcccaactgtgt ggggccgctgggggtttggagaatggtcttaactacatagacttggatttggtcaaggac ttcaaacagcgccctcaagagcgcccacctcaaccgcagcctcctccactcccggcccct catcagcctctgggcagtagtcagagcggccccaccagccgctccagcgaggatctaagc gcctatgccagcatcactttccagaagcagccagaggacctccagtag

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