Capra hircus (goat): 102187812
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Entry
102187812 CDS
T02910
Symbol
BACE2
Name
(RefSeq) beta-secretase 2
KO
K07747
beta-site APP-cleaving enzyme 2 (memapsin 1) [EC:
3.4.23.45
]
Organism
chx
Capra hircus (goat)
Pathway
chx05010
Alzheimer disease
Brite
KEGG Orthology (KO) [BR:
chx00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
102187812 (BACE2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
chx01002
]
102187812 (BACE2)
Enzymes [BR:
chx01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.23 Aspartic endopeptidases
3.4.23.45 memapsin 1
102187812 (BACE2)
Peptidases and inhibitors [BR:
chx01002
]
Aspartic peptidases
Family A1: pepsin family
102187812 (BACE2)
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Motif
Pfam:
Asp
TAXi_C
TAXi_N
Motif
Other DBs
NCBI-GeneID:
102187812
NCBI-ProteinID:
XP_017907120
UniProt:
A0A452FB32
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Position
1:140945938..141050506
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AA seq
514 aa
AA seq
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MGALARALLLPLLAQWLLRAAPALASAPFTLPLRVASATSRGAVPTPGPGPPAKPRADGL
ALALEPAGGAANFLAMVDNLQGDSGRGYYLEMQIGTPPQKLQILVDTGSSNFAVAGAPHP
YIDSYFDAERSSTYRPKGFDVTVKYTQGSWTGFVGEDVVTIPKGFNSSFLVNIATIFESE
NFFLPGIRWNGILGLAYATLAKPSSSLETFFDSLVAQAKIPNIFSMQMCGAGLPVAGSGT
NGGSLVLGGIEPTLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDS
GTTLLRLPQKVFDAVVEAVARTSLIPEFSEGFWTGSQLACWTNSETPWSYFPKISIYLRD
ENSSRSFRITILPQLYIQPMMGAGLNYECYRFGISPSTNALVIGATVMEGFYVVFDRARK
RVGFAASPCAEIAGAPVSEISGPFSTEDIASNCVPALPLNEPILWIVSYTLMSVCGLILL
VLITLLLLPVRCRHHPRDPEVVNDESSLVRHRWK
NT seq
1545 nt
NT seq
+upstream
nt +downstream
nt
atgggcgcgctggcccgggcgctgctgctgccgctgctggctcagtggctcctacgagcg
gccccggcgctggcctccgcgcccttcacgctgcctctccgggtggcctcggccacgagc
cggggggctgtgcctaccccggggcccggaccccccgctaagccccgcgcggacggcctg
gcgctcgccctggagcccgctgggggtgcggccaacttcttggctatggtggataacctg
cagggggactccggccgcggctactacctggagatgcagatcgggacccccccgcagaag
ctgcagatactcgttgacaccggaagcagcaactttgccgtggctggggccccgcatccc
tatatcgactcttactttgatgcggagaggtccagcacgtaccgccccaagggttttgat
gtcactgtgaagtacacgcaggggagctggaccggctttgttggggaggacgtggtcacc
atccccaaaggcttcaacagttcttttcttgtcaacatcgccaccatatttgagtcagag
aatttctttctgcctgggattagatggaatgggatacttggactggcttatgctaccctg
gccaagccttcaagttctctggagaccttctttgattccctcgtggcacaagcaaaaatc
cccaacatcttctccatgcagatgtgtggggccggactgccagtagctggatctggtacc
aacggaggtagtcttgtcctaggtggaattgaaccaactttgtacaaaggagacatctgg
tacacccctattaaggaggagtggtattatcagatagaaattctaaaattggaaatcgga
ggccagagccttaatctggactgcagagagtacaatgcagacaaggccatcgtggacagt
ggcaccacgctgctgcgcctgccccagaaggtgtttgacgccgtggtggaggctgtggcc
cgcacgtctctgattccagaattctctgaaggtttctggactggttcccagctggcatgc
tggacgaattctgaaacaccttggtcttatttccctaaaatctccatctacctgagagac
gagaactccagcagatcattccgtataactatcctgcctcagctttacattcagcccatg
atgggggctggcctgaattatgaatgttaccggttcggcatctcgccttccaccaacgca
ctggtgattggtgctactgtcatggagggcttctacgtggtctttgacagagctcggaag
agagtgggcttcgcagccagcccctgtgcagaaattgcaggtgctccggtgtctgaaatt
tctgggcctttctcaacagaggacatagccagcaactgcgtccctgccctgccgttgaac
gagcccattttgtggatcgtctcctatactctcatgagcgtgtgtggactcatccttctt
gttttaatcaccctgctgctacttccggtccggtgtaggcatcacccccgagatcccgag
gtggtcaacgatgagtcctcgctcgtacggcatcgctggaaatga
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