Capra hircus (goat): 102189798 Help Entry 102189798         CDS       T02910                                  Symbol ADCY5 Name (RefSeq) adenylate cyclase type 5   KO K08045   adenylate cyclase 5 [EC:4.6.1.1] Organism chx  Capra hircus (goat) Pathway chx00230   Purine metabolism chx01100   Metabolic pathways chx01522   Endocrine resistance chx04015   Rap1 signaling pathway chx04022   cGMP-PKG signaling pathway chx04024   cAMP signaling pathway chx04062   Chemokine signaling pathway chx04072   Phospholipase D signaling pathway chx04081   Hormone signaling chx04082   Neuroactive ligand signaling chx04114   Oocyte meiosis chx04211   Longevity regulating pathway chx04213   Longevity regulating pathway - multiple species chx04261   Adrenergic signaling in cardiomyocytes chx04270   Vascular smooth muscle contraction chx04371   Apelin signaling pathway chx04540   Gap junction chx04611   Platelet activation chx04713   Circadian entrainment chx04714   Thermogenesis chx04723   Retrograde endocannabinoid signaling chx04724   Glutamatergic synapse chx04725   Cholinergic synapse chx04726   Serotonergic synapse chx04727   GABAergic synapse chx04728   Dopaminergic synapse chx04750   Inflammatory mediator regulation of TRP channels chx04911   Insulin secretion chx04912   GnRH signaling pathway chx04913   Ovarian steroidogenesis chx04914   Progesterone-mediated oocyte maturation chx04915   Estrogen signaling pathway chx04916   Melanogenesis chx04918   Thyroid hormone synthesis chx04921   Oxytocin signaling pathway chx04923   Regulation of lipolysis in adipocytes chx04924   Renin secretion chx04925   Aldosterone synthesis and secretion chx04926   Relaxin signaling pathway chx04927   Cortisol synthesis and secretion chx04928   Parathyroid hormone synthesis, secretion and action chx04934   Cushing syndrome chx04935   Growth hormone synthesis, secretion and action chx04970   Salivary secretion chx04971   Gastric acid secretion chx04972   Pancreatic secretion chx04976   Bile secretion chx05012   Parkinson disease chx05030   Cocaine addiction chx05031   Amphetamine addiction chx05032   Morphine addiction chx05034   Alcoholism chx05163   Human cytomegalovirus infection chx05166   Human T-cell leukemia virus 1 infection chx05200   Pathways in cancer chx05207   Chemical carcinogenesis - receptor activation chx05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:chx00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     102189798 (ADCY5)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     102189798 (ADCY5)    04371 Apelin signaling pathway     102189798 (ADCY5)    04072 Phospholipase D signaling pathway     102189798 (ADCY5)    04024 cAMP signaling pathway     102189798 (ADCY5)    04022 cGMP-PKG signaling pathway     102189798 (ADCY5)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     102189798 (ADCY5)    04081 Hormone signaling     102189798 (ADCY5)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     102189798 (ADCY5)   09144 Cellular community - eukaryotes    04540 Gap junction     102189798 (ADCY5)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     102189798 (ADCY5)    04062 Chemokine signaling pathway     102189798 (ADCY5)   09152 Endocrine system    04911 Insulin secretion     102189798 (ADCY5)    04923 Regulation of lipolysis in adipocytes     102189798 (ADCY5)    04912 GnRH signaling pathway     102189798 (ADCY5)    04913 Ovarian steroidogenesis     102189798 (ADCY5)    04915 Estrogen signaling pathway     102189798 (ADCY5)    04914 Progesterone-mediated oocyte maturation     102189798 (ADCY5)    04921 Oxytocin signaling pathway     102189798 (ADCY5)    04926 Relaxin signaling pathway     102189798 (ADCY5)    04935 Growth hormone synthesis, secretion and action     102189798 (ADCY5)    04918 Thyroid hormone synthesis     102189798 (ADCY5)    04928 Parathyroid hormone synthesis, secretion and action     102189798 (ADCY5)    04916 Melanogenesis     102189798 (ADCY5)    04924 Renin secretion     102189798 (ADCY5)    04925 Aldosterone synthesis and secretion     102189798 (ADCY5)    04927 Cortisol synthesis and secretion     102189798 (ADCY5)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     102189798 (ADCY5)    04270 Vascular smooth muscle contraction     102189798 (ADCY5)   09154 Digestive system    04970 Salivary secretion     102189798 (ADCY5)    04971 Gastric acid secretion     102189798 (ADCY5)    04972 Pancreatic secretion     102189798 (ADCY5)    04976 Bile secretion     102189798 (ADCY5)   09156 Nervous system    04724 Glutamatergic synapse     102189798 (ADCY5)    04727 GABAergic synapse     102189798 (ADCY5)    04725 Cholinergic synapse     102189798 (ADCY5)    04728 Dopaminergic synapse     102189798 (ADCY5)    04726 Serotonergic synapse     102189798 (ADCY5)    04723 Retrograde endocannabinoid signaling     102189798 (ADCY5)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     102189798 (ADCY5)   09149 Aging    04211 Longevity regulating pathway     102189798 (ADCY5)    04213 Longevity regulating pathway - multiple species     102189798 (ADCY5)   09159 Environmental adaptation    04713 Circadian entrainment     102189798 (ADCY5)    04714 Thermogenesis     102189798 (ADCY5)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102189798 (ADCY5)    05207 Chemical carcinogenesis - receptor activation     102189798 (ADCY5)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     102189798 (ADCY5)    05163 Human cytomegalovirus infection     102189798 (ADCY5)   09164 Neurodegenerative disease    05012 Parkinson disease     102189798 (ADCY5)   09165 Substance dependence    05030 Cocaine addiction     102189798 (ADCY5)    05031 Amphetamine addiction     102189798 (ADCY5)    05032 Morphine addiction     102189798 (ADCY5)    05034 Alcoholism     102189798 (ADCY5)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     102189798 (ADCY5)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     102189798 (ADCY5)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     102189798 (ADCY5) Enzymes [BR:chx01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      102189798 (ADCY5) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  AC_N Guanylate_cyc Adcy_cons_dom TBK1_ULD GBR2_CC Motif Other DBs NCBI-GeneID:  102189798 NCBI-ProteinID:  XP_017901240 UniProt:  A0A452FR89 LinkDB All DBs Position 1:complement(67429732..67587603) Genome browser AA seq 1259 aa AA seqDB search MSSSKSVSPPGYAAQTAAAPASRGGPEHRSAWGEADSRANGYPQAPGGSARGSTKRPGGA VTPQQQQRLASRWRSDDEDDPPLSGDDPLAGGFGFSFRSKSAWQERGGDDCGRGSRRQRR GAAGGGSTRAPPAGSGGGSAAAAAAAGGTEVRPRSVELGLEERRGKGRAAEDLEAGAVEE DEGSGDGGSSAGSGSGPGAVLSLGACCLALLQIFRSKKFPSDKLERLYQRYFFRLNQSSL TMLMAVLVLVCLVMLAFHAARPPLQLPYLAVLAAAVGVILVMAVLCNRAAFHQDHMGLAC YALIAVVLAVQVVGLLLPQPRSASEGIWWTVFFIYTIYTLLPVRMRAAVLSGVLLSALHL AIALRTNAQDQFLLKQLVSNVLIFSCTNIVGVCTHYPAEVSQRQAFQETRECIQARLHSQ RENQQQERLLLSVLPRHVAMEMKADINAKQEDMMFHKIYIQKHDNVSILFADIEGFTSLA SQCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVEMGM DMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGKAG RIHITKATLNYLNGDYEVEPGCGGERNAYLKEHSIETFLILRCTQKRKEEKAMIAKMNRQ RTNSIGHNPPHWGAERPFYNHLGGNQVSKEMKRMGFEDPKDKNAQESSNPEDEVDEFLGR AIDARSIDRLRSEHVRKFLLTFREPDLEKKYSKQVDDRFGAYVACASLVFLFICFVQITV VPHSVFMLSFYLTCFLLLTLVVFVSVIYSCVKLFPAPLQTLSRKIVRSKMNSTLVGVFTI TLVFLSAFVNMFTCNSKDLFGCLGDEHNISASQVNACHVVESAVNYSLGDEQGFCGSSWP NCNFPEYFTYSVLLSLLACSVFLQISCIGKLVLMLAIELIYVLVVEVPGVTLFDNADLLV TANAIDFNNNGTSQCPEHPTKVALKVVTPVIISVFVLALYLHAQQVESTARLDFLWKLQA TEEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANFSE FYVELEANNEGVECLRLLNEIIADFDEIISEDRFRQLEKIKTIGSTYMAASGLNDSTYDK VGKTHIKALADFAMKLMDQMKYINEHSFNNFQMKIGLNIGPVVAGVIGARKPQYDIWGNT VNVASRMDSTGVPDRIQVTTDMYQVLAANTYQLECRGVVKVKGKGEMMTYFLNGGPPPS NT seq 3780 nt NT seq  +upstreamnt  +downstreamnt atgtccagctccaaaagcgtgagccccccgggctacgcggcgcagacagcggcggcgccg gcgtcccggggaggcccggaacaccgctccgcgtggggagaggccgactcccgcgccaat ggctacccccaagcccccgggggttcggcccgcggctccaccaagagacctgggggggcg gtgaccccgcagcagcaacagcgcctggccagccgctggcgcagcgacgacgaagacgat cctccgctgagtggcgatgaccccctggccgggggcttcggcttcagcttccgttccaag tcggcctggcaggagcgcggcggcgacgactgcggtcgcggcagccggcggcagcggcgg ggcgcggccggcgggggcagcacccgggcgccccctgcgggcagcggcggcggttcggcg gctgcggccgccgcagcgggaggaacggaggtgcgcccccgttcggtggagctaggcctg gaggagcggcgtggcaagggccgcgcggccgaagatctggaggccggcgccgtcgaggaa gacgaagggtccggggatgggggcagctcggcaggctcgggctcggggcctggcgcggtg ctgtcgctgggcgcctgctgcctggcactgctgcagatattccgctcgaagaagttccca tcggacaagctggagcggctgtaccagcgctacttcttccgtctgaaccagagcagcctc acgatgctcatggctgtgctggtgctcgtgtgcctagtcatgttggccttccacgccgca cggcccccgctgcagctgccctatctggccgtcctagcggccgccgtgggtgtgatcctc gttatggccgtgctctgcaaccgtgccgccttccaccaggaccacatgggcctggcctgc tacgcgcttatcgccgtggtgctggccgtccaggtggtgggcctgctgctgccccagccg cgcagtgcctccgagggcatctggtggactgtgtttttcatctatacgatctacacgctc ctgcccgtgcgcatgcgggctgcggtactcagcggggtgctcctgtccgccctccacctg gccatcgccctgcgcaccaacgcccaggatcagttcctgctcaagcagctcgtctccaat gtcctcattttctcctgcaccaacatcgtgggtgtgtgcacccactacccggctgaggtc tcgcagagacaggccttccaggagacccgggagtgcatccaggcgcggctccactcgcag cgggagaaccagcagcaggagcggctcctgctgtctgtccttccccgtcacgttgccatg gagatgaaagctgacatcaacgccaaacaggaggatatgatgttccataagatttacatc cagaaacatgacaacgtgagcatcctgtttgctgacatcgagggtttcaccagcctggca tcccagtgcactgcccaggagctggtcatgaccctcaatgagctcttcgcccgcttcgac aagctggctgcggagaatcactgtttacgtattaagatcctgggagattgttattactgt gtctcagggctgcctgaagccagggctgaccacgcccactgctgcgtggagatgggcatg gacatgatcgaggccatctcgctggtccgggaggtgacaggtgtgaacgtgaacatgcgt gtgggaattcacagcgggagagtgcactgcggtgtcctcggcctcaggaagtggcagttc gatgtctggtctaacgatgtcacactggccaaccacatggaggctggaggcaaggcggga cgcatccacatcaccaaggccacactcaactacttgaatggtgactacgaggtggagcca ggctgtgggggcgagcgcaacgcctacctcaaggagcacagtatcgagacctttctcatc ctgcgctgcacccagaagcggaaagaagaaaaggccatgattgccaagatgaaccgccag agaaccaactccatcgggcacaacccgcctcactggggggccgagcgccccttctataac cacctgggtggcaaccaggtgtccaaggagatgaagcggatgggctttgaagaccccaag gacaagaatgcccaggaaagttcgaaccctgaggatgaagtggatgaatttctgggccgt gccattgatgccaggagcatcgacaggctgcgatccgaacatgtgcgcaagttcctcttg accttcagggagcctgacttagagaagaagtactccaagcaagtggatgaccgattcggt gcctacgtggcctgtgcctcgctcgtcttcctcttcatctgctttgtccagatcaccgtc gtgccccactccgtgttcatgttgagtttctacctgacctgtttcctgctgctgaccttg gtggtgtttgtgtccgtgatctattcttgcgtgaagctcttcccggccccgctgcagacc ctctccaggaagatcgtgaggtccaagatgaacagcaccctagtgggggtgttcaccatc accctcgtgttcctgtcggctttcgtcaacatgttcacgtgcaactccaaggacctgttt ggctgcctgggggacgagcacaacatcagtgccagtcaggtcaacgcgtgccacgtggtg gagtcggccgtcaactacagtctgggtgatgagcagggcttctgcggcagctcctggccc aactgcaacttccccgagtacttcacctacagcgtgctgctcagcctgctggcctgctcc gtgttcctgcagatcagctgcatcgggaagctggtgctcatgctggccatcgagctcatc tacgtgctcgtcgttgaggtgcccggtgtcacactctttgacaatgccgacctcctggtc acggccaacgccatagacttcaacaacaacgggacctcccagtgccctgagcatccgacc aaggtggcgctgaaggtggtgacgcccgtcatcatctctgtcttcgtgctggccctgtac ctgcacgcccagcaggtggagtccactgcccgcctcgacttcctctggaaacttcaggcc acagaggagaaggaggagatggaggagctgcaggcttacaaccggcggctgctgcacaat attctgcccaaggacgtggccgcacacttcctggcccgtgaacggcgcaacgacgagctc tactatcagtcgtgcgagtgcgtggccgtcatgttcgcctccatcgccaacttctccgag ttctacgtggaactggaggccaacaacgagggcgtcgagtgcctgcggctgctcaacgag atcatcgcagactttgacgagatcattagtgaggaccggttcaggcagctggaaaagatc aagaccatcggcagcacctacatggccgcctcgggcctcaatgactccacctacgacaag gtgggcaagacccacatcaaagccctggccgacttcgccatgaagttgatggaccaaatg aagtacatcaacgagcactctttcaacaacttccagatgaagatcgggctcaatattggc cccgtggtggcgggcgtgatcggagcccgcaagcctcagtacgacatctggggcaatacg gtgaacgtggccagccgcatggacagcaccggtgtgcccgaccgcatccaggtcaccaca gacatgtaccaggtgctggccgccaacacgtaccagctggagtgccggggtgtggtcaag gtcaagggcaaaggcgagatgatgacctacttcctcaacggagggcccccgcccagttag

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