Capra hircus (goat): 108637286 Help Entry 108637286         CDS       T02910                                  Symbol IRS2 Name (RefSeq) insulin receptor substrate 2   KO K07187   insulin receptor substrate 2 Organism chx  Capra hircus (goat) Pathway chx04022   cGMP-PKG signaling pathway chx04068   FoxO signaling pathway chx04081   Hormone signaling chx04140   Autophagy - animal chx04152   AMPK signaling pathway chx04211   Longevity regulating pathway chx04213   Longevity regulating pathway - multiple species chx04910   Insulin signaling pathway chx04920   Adipocytokine signaling pathway chx04923   Regulation of lipolysis in adipocytes chx04930   Type II diabetes mellitus chx04931   Insulin resistance chx04932   Non-alcoholic fatty liver disease chx04935   Growth hormone synthesis, secretion and action chx05010   Alzheimer disease chx05206   MicroRNAs in cancer Brite KEGG Orthology (KO) [BR:chx00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     108637286 (IRS2)    04022 cGMP-PKG signaling pathway     108637286 (IRS2)    04152 AMPK signaling pathway     108637286 (IRS2)   09133 Signaling molecules and interaction    04081 Hormone signaling     108637286 (IRS2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     108637286 (IRS2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     108637286 (IRS2)    04923 Regulation of lipolysis in adipocytes     108637286 (IRS2)    04920 Adipocytokine signaling pathway     108637286 (IRS2)    04935 Growth hormone synthesis, secretion and action     108637286 (IRS2)   09149 Aging    04211 Longevity regulating pathway     108637286 (IRS2)    04213 Longevity regulating pathway - multiple species     108637286 (IRS2)  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     108637286 (IRS2)   09164 Neurodegenerative disease    05010 Alzheimer disease     108637286 (IRS2)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     108637286 (IRS2)    04932 Non-alcoholic fatty liver disease     108637286 (IRS2)    04931 Insulin resistance     108637286 (IRS2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  IRS PH PH_11 MEKK4_N Motif Other DBs NCBI-GeneID:  108637286 NCBI-ProteinID:  XP_017911854 LinkDB All DBs Position 12:1636947..1667327 Genome browser AA seq 1327 aa AA seqDB search MASPPEHGPPGPAGGDGPNLNNNNNNNNHSVRKCGYLRKQKHGHKRFFVLRGPGAGGDEA GAGGGPAPQPPRLEYYESEKKWRSKAGAPKRVIALDCCLNINKRADAKHKYLIALYTKDE YFAVAAENEQEQEGWYRALTDLVSEGRAGAGDAPPAAAATSGSCSASLPGALGGSAGAAA ADDSYGLVAPATAAYREVWQVNLKPKGLGQSKNLTGVYRLCLSARTIGFVKLNCEQPSVT LQLMSIRRCGHSDSFFFIEVGRSAVTGPGELWMQADDSVVAQNIHETILEAMKALKELFE FRPRSKSQSSGSSATHPISVPGARRHHHLVNLPPSQTGLVRRSRTDSLAATPPAAKCSAC RVRTASEGDGGAAAGAGAGAGAGAAAGSPLSPGPVRAPLSRSHTLSGGRAGKTALAPAGG GLQHSRSMSMPVAHSPPAATSPGSLSSSSGHGSGSYPPPPGPHPHLQHPLHPQRPSSGSA SASGSPSDPGFMSLDEYGSSPGDLRVYCGHRSNTPESIAETPPARDGSAGELYGYMTMER PLSHCGGRAYRRVSGDGAPDLDRGLRKRTYSLTTPARQRPAPQPSSASLDEYTLMRATFS GSSGRLCPSCPASSPKVAYHPYPEDYGDIEIGSHRSSSSNLGTDDGYVPMTPGVALLGTG SGSCKGDDYMPMSPTSVSAPKQILQPRAAPAALPPAGAAVPTPASAAGRAFPGTAGGYKT GSPAESSPEDSGYMRMWCGSKLSMESADGKLLPNGDYLNMSPSDAGTTGTPPDFFSAAGE TPRGMPGYCYSSLPRSYKAPHACHGDSDQYVLMSSPVGRVLEEEQLEPAPGPAQPASAFP AAAAGSGHPPPPHPAVPSPGRLGGGGGSRPDGFLAQRCRAVRPTRLSLEGLPALPRMHEY PLPPEPRSPGEYINIDFGEAGARLSPPAPPLLASAASSSSLLSASSPASSLGSGTPGTSG DSRQRSPLSDYMNLDFSSPKSPQPGAQGRDPVGSLDALLSPEASVYPPLPPRPAAPSSAL QPPPPPPPPGELYRLPAAPASKGPGAASSLSSDTGDNGDYTEMAFGVAATPPQPIVAPPK PDGARVSSPVSGLKRLSLMDQVSGVEAFLQAGQPPDPHRGAKVIRADPQGGRRRHSSETF SSTTTVTPVSPSFAHTPKRHNSASVENVSLRKGSEGGGGGGSSGILGGCDEPPSSPRQLP PPTPQQARAWTPAQPGGGLVGCPGGTSSPMRRETSTGFQNGLNYIAIDVRDEPGLSPPLQ QHPHAQTGDRSAWGRTRSLGGLISAVGAGSPAAVCGGPGPGALPAANAYASIDFLTHHLK EATVVKE NT seq 3984 nt NT seq  +upstreamnt  +downstreamnt atggcgagcccgccggagcacgggccccccgggccggcgggcggggacggccccaacctc aataacaacaacaacaacaacaaccacagcgtgcgcaagtgcggctacctgcgcaagcag aagcacggccacaagcgcttcttcgtgctgcgcgggcccggcgcgggcggcgacgaggcg ggcgcgggcggaggcccggcgccgcagccgccgcggctcgagtactacgagagcgagaag aagtggcggagcaaggcgggcgccccgaagcgggtcatcgcgctcgactgctgcctgaac atcaacaagcgcgccgacgccaagcacaagtacctgatcgccctctacaccaaggacgag tacttcgccgtggccgccgagaacgagcaggagcaggagggctggtaccgcgcgctcacc gacctggtcagcgagggccgcgcgggcgccggcgacgcgccccccgccgccgccgccacc tccgggtcctgcagcgcctccctgcccggcgccctgggcggctcggcgggcgccgccgcg gccgatgacagctacgggctggtggcgcccgccacggccgcctaccgcgaggtgtggcag gtaaacctgaagcccaagggcctgggccagagcaagaacctgacgggcgtgtaccgcctg tgcctgtcggcgcgcaccatcggcttcgtgaagctcaactgcgagcagccgtcggtgacg ctgcagctcatgagcatccgccgctgcggccactcggacagcttcttcttcatcgaggtg ggccgctcggccgtgacgggccccggcgagctgtggatgcaggcggacgactcggtggtg gcgcagaacatccacgagaccatcctggaggccatgaaggcgctcaaggagctcttcgag ttccggccgcgcagcaagagccagtcgtccggctcgtcggccacgcaccccatcagcgtg cctggagcgcgccgccaccaccacttggtcaacctgcccccgagccagacgggactggtg cgccgctcgcgcaccgacagcctggctgccaccccgcccgccgccaagtgcagcgcgtgc cgggtgcgcacagccagcgagggcgacggcggcgccgcggcgggggcgggggcgggggcg ggggccggggcggcggcgggcagccccctgagcccgggcccggtgcgcgcgcccctgagc cgctcgcacacgctgagcggcggccgcgcgggcaagacggcgctggcgccggcagggggc ggcctgcagcacagccgctccatgtccatgcccgtggcgcactcgcccccggcggctacc agccccggcagcctgtcgtccagcagcgggcacggctcgggctcctacccgccgcccccc ggcccgcacccgcacctgcagcaccccctgcacccccagcgcccctccagcggcagcgcc tcggcctcgggctcccccagcgaccccggcttcatgtccttggacgagtatggctccagc cccggggacctgagggtctactgcggccaccggagcaacacgcccgagtccatagctgag acgcccccggcgcgggacggcagcgcgggcgagctgtacggctacatgaccatggagcgg ccgctgagccactgcggcggccgcgcctaccgcagggtctccggggatggcgccccagac ttggaccgagggctgagaaagcggacttactcgctgaccacgcctgcccggcagcggccc gcgccccagccgtcctccgcgtccctggatgagtacaccttgatgcgggccaccttctcg ggcagctccggccgcctgtgcccatcctgccccgcgtcttctcccaaagtggcctaccac ccgtaccctgaggactacggcgacatcgagatcggctcgcaccgcagctccagcagtaac ctgggcacggacgacggctacgtgcccatgaccccaggcgtggccctcctggggacgggc agcgggagctgcaagggcgacgactacatgcccatgagccccaccagcgtgtcggccccg aagcagatcttgcagccgcgcgccgcacccgccgccttgccccctgcgggggccgcggtg cccacgcccgcgtcggcggccggcagggctttcccgggcactgcgggcggctacaagacc ggctccccggccgagagctcccccgaggacagcgggtacatgcgcatgtggtgtggttcc aagctgtccatggagagcgccgacggcaagctgctgcccaacggggactacctcaacatg tcccccagcgacgcgggcaccacgggcaccccgcccgacttcttctcggccgcgggggag acgccgcggggcatgcccggctactgctacagctctctgccccgctcctacaaggccccc cacgcctgccacggcgacagcgaccagtacgtgctcatgagctcgcctgtgggccgggtc ctggaggaggagcagctggagccggcccccggccccgcgcagccggccagtgccttcccg gccgcggcggctggcagcggccaccccccgccccctcatcccgccgtgccttctcccggg aggctcggcggtggcggaggcagccgccccgacggcttcctggcccagcgctgccgggca gtgaggcccacgcgcctgtccctggaggggctgccggccctgccccgcatgcacgagtac ccgctgccccccgagcccaggagtccaggcgagtacatcaacatcgacttcggggaggcc ggcgcgcgcctgtcgccgcccgcgcccccactcctggcctcggccgcctcgtcgtcctcg ctgttgtccgccagcagcccggcctcgtccctgggctctggcaccccgggcacgagcggg gacagccggcagcgctccccgctctccgactacatgaacctcgacttcagctcgcctaag tcgccgcagccgggcgcccagggccgggaccccgtaggctccttggacgccctgttgtcc cccgaggcctccgtgtacccgccgctgcccccgcgcccggccgccccctcctcggccctg cagccgccgccgccgccgcccccgccaggcgagctgtaccgcctgcctgcggcacccgcc tccaagggcccgggcgcggcctcctctttgtcctcggacacgggggacaacggtgactac accgagatggcctttggcgtggccgccaccccgccacaaccaattgtggcgcccccaaag cccgacggtgcccgcgtgagcagcccggtgtcaggcctcaagaggctgagcctcatggat caggtgtcgggggtcgaggccttcctgcaggccggccagcccccagacccgcaccggggg gccaaggtcatccgcgcggacccgcaggggggccgccgccgccacagctccgagaccttc tcctcgaccaccactgtgacccccgtgtccccgtccttcgctcacacccccaagcgtcac aactcggcctcggtggagaacgtctctctcaggaaaggcagcgaaggaggcggcggcggg ggcagcagcggcatcctgggtgggtgcgatgagcccccctcgtcgccccgccagttgccc cccccgacacctcagcaggcgcgggcctggacgccggctcagcccggcggcggcctggtc ggctgtcccgggggcaccagctcaccgatgcgccgggagacctccaccggcttccagaac ggcctcaactacatcgccatcgacgtgagggacgagccggggctgtcgccgcccctgcag cagcacccgcacgcgcagacgggcgacaggagcgcctggggccgcacccggagcctcggg ggtctcatcagcgccgtgggcgccggcagccctgccgcggtgtgcggagggccgggccct ggcgccctgcccgcggccaacgcctacgccagcatcgacttcttgacgcatcacctgaag gaggccacggtggtgaaagagtga

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