KEGG   Carboxydothermus hydrogenoformans: CHY_1100
Entry
CHY_1100          CDS       T00287                                 
Symbol
ligA
Name
(GenBank) DNA ligase, NAD-dependent
  KO
K01972  DNA ligase (NAD+) [EC:6.5.1.2]
Organism
chy  Carboxydothermus hydrogenoformans
Pathway
chy03030  DNA replication
chy03410  Base excision repair
chy03420  Nucleotide excision repair
chy03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:chy00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    CHY_1100 (ligA)
   03410 Base excision repair
    CHY_1100 (ligA)
   03420 Nucleotide excision repair
    CHY_1100 (ligA)
   03430 Mismatch repair
    CHY_1100 (ligA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:chy03032]
    CHY_1100 (ligA)
   03400 DNA repair and recombination proteins [BR:chy03400]
    CHY_1100 (ligA)
Enzymes [BR:chy01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.2  DNA ligase (NAD+)
     CHY_1100 (ligA)
DNA replication proteins [BR:chy03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    Other elongation factors
     CHY_1100 (ligA)
DNA repair and recombination proteins [BR:chy03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA ligase
     CHY_1100 (ligA)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     CHY_1100 (ligA)
   MMR (mismatch excision repair)
    DNA ligase
     CHY_1100 (ligA)
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHDIR (short-homology-dependent illegitimate recombination)
     RecET pathway
      CHY_1100 (ligA)
SSDB
Motif
Pfam: DNA_ligase_aden DNA_ligase_OB HHH_2 BRCT HHH_5 DNA_ligase_ZBD Nlig-Ia HHH PTCB-BRCT HHH_8 BRCT_2 5_3_exonuc
Other DBs
NCBI-ProteinID: ABB14207
UniProt: Q3AD38
LinkDB
Position
974637..976631
AA seq 664 aa
MDKEAVKKRIEELRALLHYHNYRYYVLDQPEISDAEYDRMLRELISLEQQYPEFITPDSP
SQRVGGEVAKEFREVAHLKPMYSLDNAFGPEDLKEFDRRVRSLLPGQEVEYEVELKIDGL
AISLVYENGVLVRGATRGNGTTGEDITANVKTIKAIPLKLRNPIPLLEVRGEAYMPKESF
ARLNEQREERGEPLFANPRNAAAGSLRQLDPKVTAERDLSAFMYAIGEVQGYEPKTQAEL
MEWLSELGFKVNPYREVFNNIDDVINYCQSWHEKRFSLPYVIDGLVIKVNSLAQQEALGF
TAKSPRWAIAYKFPAEIAETRLKDIIVRVGRTGVLTPTAIFEPVSLAGTTVTRASLHNED
YIREKDIRIGDIIRVQKAGEIIPEVVEVVKEKRTGAEKEFVMPDTCPVCQGKAVRLPGEA
AWRCTNASCPAQLKEGIVHFASRGAMNIEGLGPAVAELLLEAGLIHNYADLYYLSAEEVA
RLPRMGKKSAENLINAIEKSKQNSLERLIYGLGIRLVGEKAARDLAVHFKELDKLIAAGE
EEIMAIPSVGPKMAASIKAFFAQKENLELIEKLKAAGVNTKYLAEVRDNRLEGLTFVLTG
TLSSFTRKEAEQLILSLGGKVSSSVSKKTSYVVVGEDPGSKLTKAKELGIPILTEEEFRQ
MVMS
NT seq 1995 nt   +upstreamnt  +downstreamnt
atggataaggaagctgtcaaaaagcgtatcgaagaacttagggcccttcttcattatcac
aactaccggtattatgttttggaccagccggaaataagcgatgccgaatatgaccggatg
ctccgggagttaatttctttggagcagcagtatcccgagtttatcactcccgattctcca
tcccagcgggtgggaggggaagttgccaaagaatttcgggaagtggctcatttaaaaccg
atgtacagtcttgataacgcctttggaccggaggatttaaaggaatttgaccggagggtc
cggtcactgttacccgggcaggaggtagagtatgaggtagagttaaaaatcgacggtctg
gctatatctttggtgtatgaaaacggagttttggtgcgaggagccacccggggtaacggt
accacgggggaagatattacggctaacgttaaaaccattaaagctatacctctaaaatta
cgaaaccccataccccttttagaagttcggggcgaagcgtacatgcccaaggaatctttt
gcccgcttaaatgagcagcgggaagagcggggggagcccttatttgccaatccccggaat
gcagcagcagggtcgttacggcagcttgaccccaaagttaccgctgaacgggacttaagt
gcttttatgtatgctattggggaagttcagggatacgagcccaaaacccaggcggaatta
atggagtggctttcggagcttgggtttaaagtaaatccttaccgggaagtatttaacaat
attgatgacgttattaattactgccagagctggcacgaaaagaggttttccctgccctat
gttattgatggtttggtaattaaagtaaatagtcttgcccagcaggaagctttggggttt
accgcaaagtctccccggtgggcgattgcttataagtttccagcggaaattgccgagacc
cggttaaaagatattatcgtacgggttggccgtaccggggttttaacaccgacggctatt
tttgaaccggtaagcctggctggcactaccgtgacgcgagcatcgctccataacgaagat
tacatccgggaaaaggatattcggattggcgatatcattagggtgcaaaaagctggcgaa
ataattccggaagtagtggaagtagtgaaggaaaagaggaccggtgctgagaaggagttt
gtcatgcctgatacttgtccggtctgccaggggaaagcggtaagacttcccggggaagca
gcctggcggtgtaccaatgcttcctgtcctgctcagttaaaagaaggcatcgtgcatttt
gcgtcaagaggagctatgaatattgaaggcctgggaccggcggtggccgagctcttattg
gaagctggcttaattcataattatgccgacctttactacttatctgccgaagaggttgcc
aggcttccgcggatggggaaaaaatcggccgaaaacctgattaatgctattgaaaaaagt
aagcaaaacagtttagaacggcttatttacggccttggaattcggcttgtaggggaaaaa
gctgcgcgggatttggcagttcattttaaggagcttgacaagttaattgccgccggggaa
gaggagatcatggcgattccttctgtggggcccaaaatggcggcttcaattaaggcgttt
tttgcccaaaaggaaaatttagaacttatcgaaaagttaaaagcagcaggagtaaacact
aagtacctggccgaggtgcgggataaccgcttagaaggattaacttttgtcttaaccgga
accctttcatccttcacccgcaaagaagcggagcaactcattttaagtctcggcggaaaa
gtaagttcttccgtttcgaaaaaaaccagttatgtagtggttggcgaagacccgggcagt
aaattaaccaaagccaaagagctgggtattccaattttaaccgaagaggagtttcgccag
atggtgatgagctaa

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