Cebus imitator (Panamanian white-faced capuchin): 108291487
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Entry
108291487 CDS
T08783
Symbol
PLCG1
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
KO
K01116
phosphatidylinositol phospholipase C, gamma-1 [EC:
3.1.4.11
]
Organism
cimi
Cebus imitator (Panamanian white-faced capuchin)
Pathway
cimi00562
Inositol phosphate metabolism
cimi01100
Metabolic pathways
cimi01521
EGFR tyrosine kinase inhibitor resistance
cimi04012
ErbB signaling pathway
cimi04014
Ras signaling pathway
cimi04015
Rap1 signaling pathway
cimi04020
Calcium signaling pathway
cimi04062
Chemokine signaling pathway
cimi04064
NF-kappa B signaling pathway
cimi04066
HIF-1 signaling pathway
cimi04070
Phosphatidylinositol signaling system
cimi04072
Phospholipase D signaling pathway
cimi04360
Axon guidance
cimi04370
VEGF signaling pathway
cimi04613
Neutrophil extracellular trap formation
cimi04650
Natural killer cell mediated cytotoxicity
cimi04658
Th1 and Th2 cell differentiation
cimi04659
Th17 cell differentiation
cimi04660
T cell receptor signaling pathway
cimi04664
Fc epsilon RI signaling pathway
cimi04666
Fc gamma R-mediated phagocytosis
cimi04670
Leukocyte transendothelial migration
cimi04722
Neurotrophin signaling pathway
cimi04750
Inflammatory mediator regulation of TRP channels
cimi04919
Thyroid hormone signaling pathway
cimi04933
AGE-RAGE signaling pathway in diabetic complications
cimi04935
Growth hormone synthesis, secretion and action
cimi05012
Parkinson disease
cimi05022
Pathways of neurodegeneration - multiple diseases
cimi05135
Yersinia infection
cimi05167
Kaposi sarcoma-associated herpesvirus infection
cimi05170
Human immunodeficiency virus 1 infection
cimi05171
Coronavirus disease - COVID-19
cimi05200
Pathways in cancer
cimi05205
Proteoglycans in cancer
cimi05206
MicroRNAs in cancer
cimi05214
Glioma
cimi05223
Non-small cell lung cancer
cimi05225
Hepatocellular carcinoma
cimi05231
Choline metabolism in cancer
cimi05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
cimi05417
Lipid and atherosclerosis
Module
cimi_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
cimi00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
108291487 (PLCG1)
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
108291487 (PLCG1)
04014 Ras signaling pathway
108291487 (PLCG1)
04015 Rap1 signaling pathway
108291487 (PLCG1)
04370 VEGF signaling pathway
108291487 (PLCG1)
04064 NF-kappa B signaling pathway
108291487 (PLCG1)
04066 HIF-1 signaling pathway
108291487 (PLCG1)
04020 Calcium signaling pathway
108291487 (PLCG1)
04070 Phosphatidylinositol signaling system
108291487 (PLCG1)
04072 Phospholipase D signaling pathway
108291487 (PLCG1)
09150 Organismal Systems
09151 Immune system
04613 Neutrophil extracellular trap formation
108291487 (PLCG1)
04650 Natural killer cell mediated cytotoxicity
108291487 (PLCG1)
04660 T cell receptor signaling pathway
108291487 (PLCG1)
04658 Th1 and Th2 cell differentiation
108291487 (PLCG1)
04659 Th17 cell differentiation
108291487 (PLCG1)
04664 Fc epsilon RI signaling pathway
108291487 (PLCG1)
04666 Fc gamma R-mediated phagocytosis
108291487 (PLCG1)
04670 Leukocyte transendothelial migration
108291487 (PLCG1)
04062 Chemokine signaling pathway
108291487 (PLCG1)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
108291487 (PLCG1)
04919 Thyroid hormone signaling pathway
108291487 (PLCG1)
09156 Nervous system
04722 Neurotrophin signaling pathway
108291487 (PLCG1)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
108291487 (PLCG1)
09158 Development and regeneration
04360 Axon guidance
108291487 (PLCG1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
108291487 (PLCG1)
05206 MicroRNAs in cancer
108291487 (PLCG1)
05205 Proteoglycans in cancer
108291487 (PLCG1)
05231 Choline metabolism in cancer
108291487 (PLCG1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
108291487 (PLCG1)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
108291487 (PLCG1)
05214 Glioma
108291487 (PLCG1)
05223 Non-small cell lung cancer
108291487 (PLCG1)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
108291487 (PLCG1)
05171 Coronavirus disease - COVID-19
108291487 (PLCG1)
05167 Kaposi sarcoma-associated herpesvirus infection
108291487 (PLCG1)
09171 Infectious disease: bacterial
05135 Yersinia infection
108291487 (PLCG1)
09164 Neurodegenerative disease
05012 Parkinson disease
108291487 (PLCG1)
05022 Pathways of neurodegeneration - multiple diseases
108291487 (PLCG1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
108291487 (PLCG1)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
108291487 (PLCG1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
108291487 (PLCG1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
cimi04131
]
108291487 (PLCG1)
Enzymes [BR:
cimi01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
108291487 (PLCG1)
Membrane trafficking [BR:
cimi04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
108291487 (PLCG1)
Endocytosis
Macropinocytosis
Phospholipase C
108291487 (PLCG1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PI-PLC-X
SH2
PI-PLC-Y
EF-hand_PLCG2
PH
C2
SH3_1
EF-hand_PLCG1
SH3_9
SH3_2
PH_12
GDPD
EF-hand_6
PH_9
EF-hand_7
Motif
Other DBs
NCBI-GeneID:
108291487
NCBI-ProteinID:
XP_017367389
Ensembl:
ENSCCAG00000023196
UniProt:
A0A2K5Q6N1
LinkDB
All DBs
Position
Unknown
AA seq
1291 aa
AA seq
DB search
MAGAASPCANGCGPGAPSDAEVLHLCRSLEVGTVMTLFYSKKSQRPERKTFQVKLETRQI
TWSRGADKIEGAIDIREIKEIRPGKTSRDFDRYQEDPAFRPDQSHCFVILYGMEFRLKTL
SLQATSEDEVNMWIKGLTWLMEDTLQAPTPLQIERWLRKQFYSVDRNREDRISAKDLKNM
LSQVNYRVPNMRFLRERLTDLEQRSGDITYGQFAQLYRSLMYSAQKMMDLPFLEASTLRA
GERPELCRVSLPEFQQFLLDYQGELWAVDRLQVQEFMLSFLRDPLREIEEPYFFLDEFVT
FLFSKENSVWNSQLDAVCPDTMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLRMG
CRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHCSIA
QQRNMAQYFKKVLGDTLLTKPVDISADGLPSPNQLKRKILIKHKKLAEGSAYEEVPTSVM
YSENDISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETSSDQGNEDEEEPKEVSS
STELHSNEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSFW
RNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHYQQVPLRCNEFEMRLSEPVPQT
NAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKIKHCRVQQE
GQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEKIGTAEPDYGALYEGRNP
GFYVEANPMPTFKCAVKALFDYKAQREDELTFTKSAIIQNVEKQEGGWWRGDYGGKKQLW
FPSNYVEEMVNPVALEPEREHLDENSPLGDLLRGVLDVPACQIAIRPEGKNNRLFVFSIS
MASVAHWSLDVAADSQEELQDWVKKIREVAQTADARLSEGKMMERRKKIALELSELVVYC
RPVPFDEEKIGTERACYRDMSSFPETKAEKYVNKAKGKKFLQYNRLQLSRIYPKGQRLDS
SNYDPLPMWICGSQLVALNFQTPDKPMQMNQALFMTGRHCGYVLQPSTMRDEAFDPFDKS
SLRGLEPCAICIEVLGARHLPKNGRGIVCPFVEIEVAGAEYDSTKQKTEFVVDNGLNPVW
PAKPFHFQISNPEFAFLRFVVYEEDMFSDQNFLAQATFPVKGLKTGYRAVPLKNNYSEDL
ELASLLIKIDIFPAKQENGDLSPFSGTSLRERGSDASGQLFHGRAREGSFESRYQQPFED
FRISQEHLADHFDSRERRAPRRTRVNGDNRL
NT seq
3876 nt
NT seq
+upstream
nt +downstream
nt
atggcgggcgccgcgtccccctgcgccaacggctgcgggcctggcgcgccctcggacgca
gaggtgctgcacctctgccgcagcctcgaggtgggcaccgtcatgactttgttctactct
aagaagtcgcagcgacccgagcggaagaccttccaggtcaagctggagacgcgccagatc
acgtggagccggggcgccgacaagatcgagggggccattgatattcgcgaaatcaaggag
atccgcccagggaagacctcacgggactttgatcgctatcaagaggaccccgctttccgg
ccggaccagtcacactgctttgtcattctctatggaatggaattccgcctgaagaccctg
agcctgcaagccacatctgaggatgaagtgaacatgtggatcaagggcttaacttggctg
atggaggatacattgcaggcacccacacccttgcagattgagaggtggctccggaagcag
ttttactcagtggatcggaatcgtgaggatcgtatatcagccaaggacctgaagaacatg
ctgtcgcaggtcaactaccgggtccccaacatgcgcttcctccgagagcgactgacggac
ctggagcagcgcagtggggacatcacctacgggcagtttgctcagctgtaccgcagcctc
atgtacagcgcccagaagatgatggacctccccttcttggaagccagtactctgagggct
ggggagcggccagagctttgccgagtgtcccttcctgagttccagcagttcctccttgac
taccagggggagctgtgggctgttgatcgcctccaggtgcaggagttcatgctcagcttc
ctccgagaccccttgcgagagattgaggagccatactttttcctggatgagtttgtcacc
ttcctgttctccaaagagaacagtgtgtggaactcgcagctggacgctgtgtgcccggac
accatgaacaaccctctttcccactactggatctcctcctcccataacacgtacctgacc
ggggaccagttctccagcgaatcctccctggaagcctatgctcgctgcctgcggatgggc
tgtcgctgcattgagttggactgctgggacggtccggatgggatgccagtcatttaccat
gggcacacacttaccaccaagatcaagttctcagatgtcctgcacaccatcaaggagcat
gcctttgtggcctcagagtacccagtcatcctttccattgaggaccactgcagcattgcc
cagcagagaaacatggcccagtacttcaagaaggttctgggggacacactcctcaccaag
cccgtggatatctctgccgatgggctcccctcacccaaccagcttaagaggaagatcctc
atcaagcacaagaagctggctgagggcagtgcctacgaggaggtgcctacatccgtgatg
tactcagagaatgacatcagcaactccatcaagaatggcatcctctacctggaggaccct
gtgaaccacgaatggtatccccactacttcgttctgaccagcagcaagatctactactct
gaggagaccagcagtgaccagggcaatgaggatgaggaagagcccaaggaggtcagcagc
agtacagagctgcactccaatgagaagtggttccatgggaagcttggggcagggcgtgat
gggcggcacatcgctgagcgcctgcttactgagtactgcatcgagaccggggcccctgac
ggctccttcctcgtgcgagagagtgagaccttcgtgggagactacacgctctctttctgg
cggaatgggaaagtccagcactgccgtatccactcccggcaagatgctgggacccccaag
ttcttcttgacagacaacctcgtctttgattccctctatgacctcatcacacactaccag
caggtgcccctgcgctgcaatgagtttgagatgcgactttcagaacctgttccacagacc
aatgcccatgagagcaaagagtggtaccacgcgagcctgaccagagcacaggctgagcat
atgctaatgcgtgtcccccgtgatggggccttcctggtgcggaagcgcaatgagcccaac
tcatatgccatctctttccgggctgagggcaagatcaagcattgccgtgtccagcaagag
ggacagactgtgatgctagggaactcggagttcgacagccttgttgacctcatcagctac
tatgagaagcacccgctataccgcaagatgaagctgcgttatcccatcaatgaggaggca
ctggagaagattggcacagctgagcctgactacggagccctgtatgagggacgcaaccct
ggtttctacgtagaggcaaaccctatgccaactttcaagtgtgcagtcaaagccctcttt
gactacaaggcccagagggaggacgagctgaccttcaccaagagtgctatcatccagaac
gtggaaaagcaagagggaggctggtggcgaggggactacggagggaagaagcagctgtgg
ttcccatcaaactatgtggaagagatggtcaaccccgtggccctggagccagagagggag
cacttggacgagaacagccccttaggggacttgctgcggggggtcttggatgtaccagct
tgtcagattgccatccgtcctgagggcaagaacaaccggctcttcgtcttctccatcagc
atggcatcggtggcccactggtccctggatgttgctgccgactcacaggaggagctgcag
gactgggtgaaaaagatccgtgaagtggcccagaccgcagatgccaggctctctgagggg
aagatgatggaacggaggaagaagatcgccctggagctctctgagcttgtcgtctactgc
cggcctgttcccttcgatgaagagaagattggcacagaacgtgcttgctaccgggacatg
tcgtccttcccggaaaccaaggctgagaaatacgtgaacaaggccaaaggcaagaagttc
cttcagtacaatcgactgcagctctcccgcatctaccccaagggccagcgactggattcc
tccaactatgatcctttgcccatgtggatctgtggcagccagctcgtggccctcaacttc
cagacccctgacaagcctatgcagatgaaccaggccctcttcatgacgggcaggcactgt
ggctacgtgctgcagccaagtaccatgcgggacgaggccttcgacccctttgacaagagc
agcctccgcgggctggagccatgtgccatctgtattgaggtgctgggggcccgtcatctg
ccgaagaatggccggggcattgtgtgtccttttgtggagattgaggtggctggagctgag
tatgacagcaccaagcagaagacagagtttgtggtggacaatggactcaaccctgtatgg
ccggccaagcccttccacttccagatcagtaaccctgaatttgcctttctgcgtttcgtg
gtgtatgaggaagacatgtttagtgaccagaatttcctggctcaggctactttcccagta
aaaggcctgaagacaggatacagagcagtgcctttgaagaacaactacagcgaggacctg
gagttggcctccctgctgatcaagattgacattttccctgccaagcaagagaacggtgac
ctcagtcccttcagtggtacatccctgcgggagcggggctcagatgcctcgggccagctg
tttcatggccgagcccgggaaggctcctttgagtcccgctaccagcagccatttgaggac
ttccgcatctcccaggagcatctcgcagaccattttgacagtcgagaacgaagggcccca
agaaggactcgggtcaatggagacaaccgcctctag
DBGET
integrated database retrieval system
