KEGG   Cebus imitator (Panamanian white-faced capuchin): 108297130
Entry
108297130         CDS       T08783                                 
Name
(RefSeq) 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1-like
  KO
K00070  3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:1.1.1.145 5.3.3.1]
Organism
cimi  Cebus imitator (Panamanian white-faced capuchin)
Pathway
cimi00140  Steroid hormone biosynthesis
cimi01100  Metabolic pathways
cimi04913  Ovarian steroidogenesis
cimi04925  Aldosterone synthesis and secretion
cimi04927  Cortisol synthesis and secretion
cimi04934  Cushing syndrome
Module
cimi_M00107  Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
cimi_M00110  C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
cimi_M00976  C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
cimi_M00977  C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:cimi00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    108297130
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    108297130
   04925 Aldosterone synthesis and secretion
    108297130
   04927 Cortisol synthesis and secretion
    108297130
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    108297130
Enzymes [BR:cimi01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.145  3beta-hydroxy-Delta5-steroid dehydrogenase
     108297130
 5. Isomerases
  5.3  Intramolecular oxidoreductases
   5.3.3  Transposing C=C bonds
    5.3.3.1  steroid Delta-isomerase
     108297130
SSDB
Motif
Pfam: 3Beta_HSD Epimerase NAD_binding_4 GDP_Man_Dehyd Polysacc_synt_2 RmlD_sub_bind NAD_binding_10 KR NmrA
Other DBs
NCBI-GeneID: 108297130
NCBI-ProteinID: XP_017375263
Ensembl: ENSCCAG00000026174
UniProt: A0A2K5QLG9
LinkDB
Position
Unknown
AA seq 373 aa
MTGWSCLVTGAGGFLGRRIIRLLMEEKELKEIRALDKAFRPEFGDEFSELQSKIKLTMLE
GDILDKSCLKRACQDITVVIHTASIIDVLGAIHRESIMNVNVKGTQLLLEACVHASVPVF
IYTSTLEVAGPNSYKEVIQNGHEDQPLENTWSAPYPYSKQLAEKAVLAANGWTLKNGGTL
YTCALRPMYIYGEGSRFISATINEGLNNSGILPSVGKFSTVNPVYVGNVAWAHILALRAL
QDPKKAPSVRGQFYYISDDTPHQSYDGLNYTLSKEFGLRLDSSWSLPLFLMYWMGFLLEV
VSFLLSPIYTYRPPFNRHTVTLSNGVYTFSYKKAQRDLAYKPLYSWEEARQKTVEWVGSL
VDRHKEMLKSKTQ
NT seq 1122 nt   +upstreamnt  +downstreamnt
atgacgggctggagctgccttgtgacaggagcaggagggtttctgggtcggaggatcatc
cgccttttgatggaggagaaggagctgaaggagatcagggccttggacaaggccttcaga
ccggaatttggggatgaattttctgagctccagagcaagatcaagctgacgatgctggaa
ggagacattctggacaagtcatgcctgaagagagcctgccaggacatcacggtcgtcatc
cacacggcctccatcattgatgtcttgggtgctattcacagagagtctatcatgaatgtc
aacgtgaaaggtacccagctcctgttggaggcctgtgtccacgctagtgtgccagtcttc
atctacaccagcaccctagaggtggctgggcccaactcctacaaggaagtcatccagaac
ggccacgaagatcagcctctggaaaacacatggtctgctccctatccgtacagcaaacag
cttgctgagaaggctgtgctggcggctaatgggtggactctcaaaaatgggggcaccttg
tacacttgtgccttaagacccatgtatatctatggggaaggaagccgattcatttctgcc
actataaatgaaggcctgaacaacagtgggatcctgccaagtgttggcaagttctccaca
gtcaacccagtgtatgttggcaacgtggcctgggcacacattctggccttgagggccctg
caggaccccaagaaggccccaagtgtccgaggacagttctattacatctcagacgacacg
cctcaccaaagctatgatggccttaattacaccctgagcaaagaattcggcctccgtctt
gattccagttggagccttcctttattcctgatgtactggatgggcttcctgctggaagtg
gtgagcttcctgctcagcccaatttacacctatcggccccctttcaaccgccacacagtg
acgttgtcaaacggtgtgtacaccttctcttacaagaaggctcagcgagatctggcatat
aagccgctctacagctgggaggaagccaggcagaaaaccgtggagtgggttggttccctt
gtggaccggcacaaggagatgctgaagtccaagactcagtga

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