KEGG   Citrobacter sp. CFNIH10: C2U53_02605
Entry
C2U53_02605       CDS       T05324                                 
Symbol
dfrA
Name
(GenBank) trimethoprim-resistant dihydrofolate reductase DfrA14
  KO
K18589  dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
Organism
cir  Citrobacter sp. CFNIH10
Pathway
cir00670  One carbon pool by folate
cir00790  Folate biosynthesis
cir01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:cir00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    C2U53_02605 (dfrA)
   00670 One carbon pool by folate
    C2U53_02605 (dfrA)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   01504 Antimicrobial resistance genes [BR:cir01504]
    C2U53_02605 (dfrA)
Enzymes [BR:cir01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     C2U53_02605 (dfrA)
Antimicrobial resistance genes [BR:cir01504]
 Gene variants
  Trimethoprim resistance genes
   Dihydrofolate reductases
    C2U53_02605 (dfrA)
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-ProteinID: AUZ62827
LinkDB
Position
pKPC-933d:145865..146347
AA seq 160 aa
MRTLKVSLMAAKAKNGVIGCGPDIPWSAKGEQLLFKALTYNQWLLVGRKTFESMGALPNR
KYAVVTRSGWTSNDDNVVVFQSIEEAMDRLAEFTGHVIVSGGGEIYRETLPMASTLHLST
IDIEPEGDVFFPSIPNTFEVVFEQHFTSNINYCYQIWKKG
NT seq 483 nt   +upstreamnt  +downstreamnt
atgagaaccttgaaagtatcattgatggctgcgaaagcgaaaaacggcgtgattggttgc
ggtccagacataccctggtccgcgaaaggggagcagctactttttaaagcattgacctac
aatcagtggcttctggtgggtcgcaagacgtttgaatctatgggcgcactccccaatagg
aaatacgcggtcgttacccgctcaggttggacatcaaatgatgacaatgtagttgtattt
cagtcaatcgaagaggccatggacaggctagctgaattcaccggtcacgttatagtgtct
ggtggcggagaaatttaccgagaaacattacccatggcctctacgctccacttatcgacg
atcgacatcgagccagagggggatgttttcttcccgagtattccaaataccttcgaagtt
gtttttgagcaacactttacttcaaacattaactattgctatcaaatttggaaaaagggt
taa

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