KEGG   Citrobacter sp. CFNIH10: C2U53_11455
Entry
C2U53_11455       CDS       T05324                                 
Name
(GenBank) methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
cir  Citrobacter sp. CFNIH10
Pathway
cir00270  Cysteine and methionine metabolism
cir00450  Selenocompound metabolism
cir00670  One carbon pool by folate
cir01100  Metabolic pathways
cir01110  Biosynthesis of secondary metabolites
cir01230  Biosynthesis of amino acids
cir04980  Cobalamin transport and metabolism
cir04981  Folate transport and metabolism
Module
cir_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:cir00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    C2U53_11455
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    C2U53_11455
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    C2U53_11455
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    C2U53_11455
   04980 Cobalamin transport and metabolism
    C2U53_11455
Enzymes [BR:cir01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     C2U53_11455
SSDB
Motif
Pfam: Met_synt_B12 S-methyl_trans Pterin_bind B12-binding_2 B12-binding
Other DBs
NCBI-ProteinID: AUZ64397
UniProt: A0A3Q8DG27
LinkDB
Position
1672794..1676477
AA seq 1227 aa
MSSKVEQLRAQLNERILVLDGGMGTMIQSYRLSEEDFRGERFADWPCDLKGNNDLLVLSK
PEVIAAIHNAYFDAGADIIETNTFNSTPIAMADYQMESLSAEINFAAAKLARACADEWTA
RTPEKPRYVAGVLGPTNRTASISPDVNDPAFRNITFDQLVAAYRESTKALVEGGSDLILI
ETVFDTLNAKAAIFAVKEELEALGIDLPIMISGTITDASGRTLSGQTTEAFYNSLRHAEP
LTFGLNCALGPDELRQYVQELSRIAECYVTAHPNAGLPNAFGEYDLDADTMAKQIREWAE
AGFLNIVGGCCGTTPEHIAAMSRAVEGLAPRPLPEIPVACRLSGLEPLNIGDDSLFVNVG
ERTNVTGSAKFKRLIKEEKYSEALDVARQQVESGAQIIDINMDEGMLDAEAAMVRFLNLI
AGEPDIARVPIMIDSSKWDVIEKGLKCIQGKGIVNSISMKEGVETFIHHAKLLRRYGAAV
VVMAFDEQGQADTRARKIEICRRAYRILTEEVGFPPEDIIFDPNIFAVATGIDEHNNYAQ
DFIGACEDIKRELPHALISGGVSNVSFSFRGNDPVREAIHAVFLYYAIRNGMDMGIVNAG
QLAIYDDLPAELRDAVEDVILNRRDDGTERLLELAERYRGSKSDEAANAQLAEWRTWEVK
KRLEYSLVKGITEFIEQDTEEARQQAARPIEVIEGPLMDGMNVVGDLFGEGKMFLPQVVK
SARVMKQAVAYLEPFIEASKEKGSSNGKMVIATVKGDVHDIGKNIVGVVLQCNNYEIVDL
GVMVPAEKILRTAKEVNADLIGLSGLITPSLDEMVNVAKEMERQGFTIPLLIGGATTSKA
HTAVKIEQNYSGPTVYVQNASRTVGVVAALLSDTQRDDFVARTRKEYETVRIQHGRKKPR
TPPVTLAAARDNDLAFDWESYTPPVAHRLGVQEVEASIETLRNYIDWTPFFMTWSLAGKY
PRILEDEVVGEEAKRLFNDANDMLDKLSAEKALNPRGVVGLFPANRVGDDIEIYRDETRT
HVLTVSHHLRQQTEKVGFANYCLSDFVAPKLTGKADYIGAFAVTGGLEEDALADAFEAQH
DDYNKIMVKALADRLAEAFAEYLHERVRKVYWGYAPNENLSNEELIRENYQGIRPAPGYP
ACPEHTEKGTIWQLLEVEKHTGMKLTESFAMWPGASVSGWYFSHPDSKYYAVAQIQRDQV
EDYAFRKGMSVSDVERWLAPNLGYDAD
NT seq 3684 nt   +upstreamnt  +downstreamnt
gtgagcagcaaagttgaacaactgcgtgcgcagttaaatgaacgtattctggtgctggac
ggcggtatgggcacgatgatccagagctatcgtctgagtgaagaggatttccgtggtgaa
cgctttgccgactggccgtgcgacctgaaaggcaacaatgacctgctggtgctgagtaag
ccagaggtgatcgccgcgattcataacgcgtactttgacgcgggcgcggacatcattgaa
accaacacgtttaactccacccccatcgcgatggcggattaccagatggaatccctgtcg
gcggagatcaactttgccgccgcgaaactggcgcgtgcctgtgccgatgagtggactgcc
cgtaccccggaaaaaccgcgctatgttgcgggcgttctcggcccaaccaaccggaccgca
tcgatctcgccggatgtgaatgacccggcatttcgtaatatcacctttgatcaactggtg
gctgcttaccgcgaatccaccaaagcgctggtggaaggtggcagtgacttgattttgatc
gaaaccgtcttcgatacgctgaacgcgaaagcggcgatttttgcggtgaaagaggagctg
gaagcgctgggcatcgacctgccgatcatgatttccggcaccatcaccgatgcttctgga
cgtaccctttccgggcaaacgacagaggcgttttacaactccctgcgccatgctgaacct
ctcactttcggcctcaactgcgcgctggggccggatgaactgcgtcagtatgtgcaggaa
ctgtctcgcattgctgaatgttacgtgactgcacacccgaacgccgggctgcccaacgct
ttcggtgaatacgatctcgatgccgatacgatggcaaaacagatccgcgaatgggccgaa
gcgggcttcctgaatatcgttggcggctgctgcggcaccacaccggaacacatcgcggca
atgagcagggcggtcgagggactggcaccgcgcccgttgccggagatcccggtggcctgc
cgcttatccggtctcgaaccgctgaatattggcgacgacagcctgtttgtaaacgtcggt
gagcgtaccaacgttaccggctccgccaaatttaagcgcctgatcaaagaagaaaaatac
agcgaagcgctggacgttgcccgtcagcaggtagaaagcggcgcacagattattgatatc
aacatggatgaggggatgctcgacgccgaagcggcgatggtgcgctttctcaacctgatc
gccggtgagcctgacattgctcgtgtgccgatcatgattgactcctcaaaatgggacgtc
atcgagaaagggctgaagtgcatccaggggaaaggcatcgttaactccatctcgatgaaa
gagggggttgaaacctttatccatcatgcgaagctgctgcgccgctacggtgcggcggtg
gtggtgatggcctttgatgagcagggccaggcggatacgcgtgcgcgtaaaatcgagatt
tgccgccgggcgtacaggatcctcaccgaggaggtgggcttcccgccggaagacatcatt
ttcgacccgaatattttcgcagtagcaaccgggatcgatgagcacaacaactacgcgcag
gactttatcggtgcctgtgaagacatcaaacgcgagctgccgcatgcgttgatctccggc
ggcgtgtccaacgtgtcattctcgttccgtggcaacgatccggtgcgcgaagccattcac
gcggtgttcctctactatgccattcgtaacggtatggacatggggattgtcaacgccggg
caactggcgatttacgacgatctccctgccgagctgcgcgatgcggtggaggatgtgatc
ctcaatcggcgtgatgacggcaccgaacgattgctggagttggcggagagatatcgcggt
agcaagagtgatgaggcggccaacgcacaactggcggagtggcgcacctgggaagtgaaa
aagcgcctcgaatactcgctggttaaaggcatcaccgagtttatcgagcaggacaccgaa
gaggcgcgtcagcaggcggcccgcccgattgaggtgattgaagggccgctgatggacggg
atgaacgtcgtcggcgacctgttcggcgaaggaaaaatgttcctgccgcaggtagtgaaa
tccgcccgcgtaatgaaacaggcggtggcgtatctcgaaccgtttatcgaagccagtaaa
gagaaaggctccagcaatggcaaaatggtcatcgccaccgtgaagggcgatgtccacgat
atcggcaaaaatatcgttggcgtggtcctgcaatgtaacaactacgaaatcgtcgatctt
ggcgtgatggtgccggcggagaaaattctccgaaccgccaaagaggtgaatgcggatctg
ataggcctttccgggctgattaccccgtcgctggacgaaatggtcaacgtggcgaaagag
atggagcgtcagggcttcaccataccgctgctgattggcggcgcgacgacctcgaaagcg
cacacggcggtgaaaatcgagcagaactacagcggccctacggtgtatgtgcagaacgct
tcgcgcaccgtcggcgtggtcgccgcgttgctttctgatacccagcgcgatgactttgtc
gcccgtacccgtaaagagtatgaaaccgtgcgcatccagcatgggcgtaagaaaccgcgc
acgccgccggtgacgctcgccgccgcgcgggataacgatctggcgtttgactgggaaagc
tataccccgccagtggcgcaccgtctgggtgtgcaggaggtcgaagccagcatcgaaacg
ctgcgtaactacatcgactggacgccgttctttatgacctggtcgctggccgggaagtat
ccgcgcattctggaagatgaagtggtaggtgaagaggcgaagcgcctgtttaacgatgcc
aacgacatgctggataaattgagcgcagagaaggcgctgaatccgcgcggtgtggtgggg
ctgttcccggcaaaccgcgtgggtgatgacatcgaaatctatcgtgacgaaacgcgaacg
cacgtgctgacggtcagccatcatctgcgtcaacagactgaaaaagtgggctttgctaac
tactgtctgtctgacttcgtggcgccgaagctgaccggcaaagcggactacatcggtgct
tttgcggtgaccggtggtctggaggaggacgcgctggcggatgcgtttgaagcgcagcac
gatgattacaacaagatcatggtgaaagcgcttgccgaccgtctggcggaagccttcgcg
gaatacctgcatgagcgcgtgcgtaaggtctactggggctatgcgccgaacgaaaatctc
agcaatgaagagctgattcgcgaaaactaccagggaattcgtccggcgccggggtacccg
gcctgtccggagcataccgagaaaggcaccatctggcagttgctggaagtggaaaagcac
accggcatgaagcttaccgaatccttcgccatgtggcctggcgcatcggtttccggctgg
tacttcagccatccggacagcaagtattacgcggttgcacagattcagcgcgatcaggtg
gaagactacgcgttccgtaaagggatgagtgtttctgacgttgagcgctggctggcccct
aacctgggctacgacgccgactga

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