Callithrix jacchus (white-tufted-ear marmoset): 100405879
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Entry
100405879 CDS
T03264
Name
(RefSeq) 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2-like isoform X1
KO
K00070
3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:
1.1.1.145
5.3.3.1
]
Organism
cjc
Callithrix jacchus (white-tufted-ear marmoset)
Pathway
cjc00140
Steroid hormone biosynthesis
cjc01100
Metabolic pathways
cjc04913
Ovarian steroidogenesis
cjc04925
Aldosterone synthesis and secretion
cjc04927
Cortisol synthesis and secretion
cjc04934
Cushing syndrome
Module
cjc_M00107
Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
cjc_M00110
C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
cjc_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
cjc_M00977
C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
cjc00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
100405879
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
100405879
04925 Aldosterone synthesis and secretion
100405879
04927 Cortisol synthesis and secretion
100405879
09160 Human Diseases
09167 Endocrine and metabolic disease
04934 Cushing syndrome
100405879
Enzymes [BR:
cjc01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
100405879
5. Isomerases
5.3 Intramolecular oxidoreductases
5.3.3 Transposing C=C bonds
5.3.3.1 steroid Delta-isomerase
100405879
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Motif
Pfam:
3Beta_HSD
Epimerase
NAD_binding_4
GDP_Man_Dehyd
Polysacc_synt_2
NAD_binding_10
NmrA
KR
Motif
Other DBs
NCBI-GeneID:
100405879
NCBI-ProteinID:
XP_035108519
LinkDB
All DBs
Position
7:154783927..154790871
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AA seq
153 aa
AA seq
DB search
MGWSCLVTGAGGFLGRRIVRLLVEEKELKEIRALDKTFRPESREEFSKNFPARSGNPSID
LTGVHTELQSKTKLTMLEGDILDEPFLKRACQDVTVVIHTASIIDVLGAIHRESIMNVNV
KGTVAWEGDKILWEGVRIKDQKEGQGREENSLR
NT seq
462 nt
NT seq
+upstream
nt +downstream
nt
atgggctggagctgccttgtgacaggagcaggagggtttctgggtcggaggatcgtccgc
ctgttggtggaggagaaggagctgaaggagatcagggccttggacaagaccttcagaccg
gagtcgagggaggaattttccaaaaacttcccagccagatctggaaatccttccattgac
ctgaccggtgttcacacagagctccagagcaagaccaagctgacgatgctggagggagac
attctggatgagccattcctgaagagagcctgccaggacgtcacggttgtcatccacacg
gcctctatcattgatgtcttgggtgccattcacagagaatccatcatgaacgtcaacgtg
aaaggtaccgtagcctgggaaggggataaaatactgtgggaaggcgtgagaattaaggat
cagaaagaaggacaaggaagggaagagaattccctccgctga
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