KEGG Orthology (KO) [BR:cjc00001]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
100896506 (DHFR2)
00670 One carbon pool by folate
100896506 (DHFR2)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
100896506 (DHFR2)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
100896506 (DHFR2)
Enzymes [BR:cjc01000]
1. Oxidoreductases
1.5 Acting on the CH-NH group of donors
1.5.1 With NAD+ or NADP+ as acceptor
1.5.1.3 dihydrofolate reductase
100896506 (DHFR2)
142 aa
MGIGKKGDLPWPPLRNEFRYFQRMTTTSSIEGKQNLVITGRKTWFSIPEKNRPLKDRINF
VLSRELQEPPQGAHFLARSLDDALNLTEQPELANKVDMIWIVGGSSVYKEAMNRPGHLKL
FVTRIMQDFESDTFFPEIDLEK