Cedecea lapagei: NCTC11466_04324
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Entry
NCTC11466_04324 CDS
T05810
Symbol
metH
Name
(GenBank) Methionine synthase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
clap
Cedecea lapagei
Pathway
clap00270
Cysteine and methionine metabolism
clap00450
Selenocompound metabolism
clap00670
One carbon pool by folate
clap01100
Metabolic pathways
clap01110
Biosynthesis of secondary metabolites
clap01230
Biosynthesis of amino acids
clap04981
Folate transport and metabolism
Module
clap_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
clap00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
NCTC11466_04324 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
NCTC11466_04324 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
NCTC11466_04324 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
NCTC11466_04324 (metH)
04980 Cobalamin transport and metabolism
NCTC11466_04324 (metH)
Enzymes [BR:
clap01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
NCTC11466_04324 (metH)
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Gene cluster
GFIT
Motif
Pfam:
Met_synt_B12
S-methyl_trans
Pterin_bind
B12-binding_2
B12-binding
Motif
Other DBs
NCBI-ProteinID:
VEC01616
UniProt:
A0A3S4IH69
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All DBs
Position
1:complement(4338427..4342215)
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AA seq
1262 aa
AA seq
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MLNISHVSDVRLFRPCSLCKYGSASPSGREKVEVKVSNNVEKLKQQLSERILVLDGGMGT
MIQSYRLDESDFRGERFAAWPCDLKGNNDLLVLTKPEIIAAIHYAYFEAGADIVETNTFN
STTIAMADYQMESLSAEINYEAAKLARACADEWTARTPGKPRYVAGVLGPTNRTASISPD
VNDPAFRNITFDQLVAAYRESTRALVEGGADLIMIETVFDTLNAKAAIFAVKEEFDALGV
DLPIMISGTITDASGRTLSGQTTEAFYNSLRHADALSFGLNCALGPDELRQYVAELSRIA
ECYVTAHPNAGLPNAFGEYDLDAEVMARQIGEWAQAGFLNIVGGCCGTTPAHIAAMSKAV
EGVAPRKLPELPIACRLAGLEPLNIGADSLFVNVGERTNVTGSAKFKRLIKEEKYSEALD
VALQQVASGAQVIDINMDEGMLDAEAAMVRFLNLIAGEPDIARVPIMIDSSKWEVIEKGL
KCIQGKGIVNSISMKEGIEPFIHHAKLVRRYGAAMVVMAFDEVGQADTRERKIEICRRAY
KILTEEVGFPPEDIIFDPNIFAVATGIEEHNNYAQDFIGACEDIKRELPHAMISGGVSNV
SFSFRGNDPVREAIHAVFLYYAIRNGMDMGIVNAGQLAIYDDLPAELRDAVEDVILNRRD
DSTERLLELAEKYRGSKSDDGANAQQAEWRSWDVVKRLEYSLVKGITEFIETDTEEARQQ
STRPIEVIEGPLMAGMNVVGDLFGEGKMFLPQVVKSARVMKQAVAYLEPYIEASKEKGAT
NGKIVLATVKGDVHDIGKNIVGVVLQCNNYEIIDLGVMVPGEKILKTARDVGADIIGLSG
LITPSLDEMVNVAKEMERQGFTLPLLIGGATTSKAHTAVKIEQNYSGPTVYVQNASRTVG
VVSALLSETQHEEFVARTRKEYEVVRTQHARKKPRTPPVTLQAARDNDLAFDWESYTPPV
AHRLGVQEVTASIETLRNYIDWTPFFMTWSLAGKYPRILEDEVVGDEAKRLFKDANDMLD
MLHRSKTMTPRGVVGLFPANRVDDDVEIYTDETRTRVKAVSRHLRQQTEKSGFPNYCIAD
FVAPKHSGKADYIGAFAVTGGIEEDDLAGAYDAQHDDYNKIMVKAVADRLAEAFAEYLHE
RVRKVYWGYAATENLSNEELIRENYQGIRPAPGYPACPEHTEKAAIWELLDVENVIGMKL
TESYAMWPGASVSGWYFSHPDSKYFAVAQIQRDQVEDYARRKGMPVSEVERWLAPNLGYD
AD
NT seq
3789 nt
NT seq
+upstream
nt +downstream
nt
atgctgaacatctctcatgtttctgacgtgcggcttttccgaccctgtagtttgtgcaag
tatgggtctgcaagtccgtcaggccgggaaaaggtggaagtgaaagtgagtaacaacgta
gagaagctgaagcaacaactgagtgaacgcatcctggtgctggacggcggtatgggaacc
atgatccagagctatcgcctcgatgagagcgacttccgtggcgagcgttttgccgcctgg
ccgtgcgacctcaaaggcaacaatgacctgctggtgctcactaagcctgaaattatcgcc
gcgattcactacgcctactttgaagctggcgcggacatcgttgaaaccaacaccttcaac
tccaccacgattgcgatggcggactaccagatggagtcgctgtcggcggaaattaactac
gaagccgctaagctggcacgagcctgtgccgatgaatggacggcgcgtacgccgggaaaa
ccacgctatgtcgccggtgttttagggccgactaaccgcacggcctccatttctccggac
gtgaacgatcctgccttccgcaatatcaccttcgatcagcttgtagcggcctatcgcgaa
tccaccagggcgctggtggaaggcggcgctgacctgatcatgatcgaaacggtgttcgat
accctgaacgctaaggccgctatctttgccgtgaaggaagagttcgatgcgcttggcgtt
gacctgccgatcatgatttccggcaccatcaccgatgcatcaggccgcacgctttccggt
cagacgacggaagctttctataactccttacgccatgccgacgcgctctccttcggccta
aactgtgcgctggggccggacgagctgcgccagtatgtcgctgagctgtcgcgcattgcc
gaatgctacgtaaccgctcaccctaacgccgggctgccgaacgcctttggtgaatacgat
ctggacgcggaagtcatggcccggcagattggcgaatgggcgcaggccgggttcctgaat
attgtcggcggctgctgcgggactacgcctgcgcacattgctgcgatgagcaaagcggtg
gagggcgttgcgccgcgtaagcttcctgagctgccgattgcctgccgcctggccgggctt
gagccgctgaacatcggcgcggacagcctgtttgttaacgtgggtgaacgcaccaacgtt
accggctctgctaaattcaaacggctgattaaagaagagaaatacagcgaggcgctggac
gttgcgctgcagcaggtcgccagcggggcgcaggtcatcgacatcaacatggatgagggg
atgcttgacgccgaagcggcgatggtgcgcttcctcaatctgattgccggcgagccggat
attgcccgcgtgccaatcatgatcgactcttcgaaatgggaagtcatcgagaaagggctg
aagtgtattcagggcaaaggcatcgttaactcaatttcgatgaaggaagggattgagccg
tttatccaccacgcgaagctggtgcggcgctacggcgcggccatggtggtgatggcgttc
gacgaagtgggccaggcggatacccgcgagcgcaaaatcgagatctgccgccgtgcctac
aaaattcttaccgaagaggtgggcttcccgccggaagacatcatcttcgacccgaacatc
tttgcggtggcgaccgggatagaagagcacaataactatgcccaggactttatcggcgcc
tgcgaagatattaagcgcgagctgccgcatgcgatgatctccggcggcgtatccaacgtc
tccttctctttccgcggcaacgaccctgtgcgcgaagccatccacgcggtattcctttac
tacgcgatccgcaacggtatggacatggggattgtgaatgccgggcagctggctatttac
gacgatctcccagcagagctgcgtgacgccgtagaagacgtcattcttaaccgccgcgac
gacagtaccgagcggctgctggagctggccgagaaatatcgcggcagcaaaagcgatgac
ggcgccaatgctcaacaggccgagtggcgcagctgggatgtcgttaagcgccttgaatac
tcgctggtgaaagggatcaccgagtttatcgaaaccgataccgaagaagcccgccagcag
tcgacccgcccaatcgaagtgatcgaaggcccgctgatggcagggatgaacgtggtcggt
gacctgttcggagaggggaaaatgttcctgccgcaggtggtgaaatcggcccgcgttatg
aagcaggcggtggcttatctggagccgtatatcgaagccagtaaggaaaaaggggcgact
aacggcaagatcgtcctcgcgacggtgaaaggcgatgtacacgatatcggcaagaacatc
gtcggcgtggtgctgcaatgtaacaactacgaaattatcgatctcggcgtaatggtgccc
ggtgagaagattttaaaaaccgcccgtgatgtgggcgcggatattatcggcctctccggg
ctgattaccccttcgctggacgaaatggtgaacgttgccaaagagatggagcgccagggc
tttacgctgccgctgctgatcggcggggctacgacgtcaaaagcccataccgcggtgaaa
atcgagcaaaactacagcggcccgaccgtttatgtgcagaacgcctcgcgtaccgtgggc
gtagtctctgcgctgctttcagaaacccagcatgaagagtttgttgcccgtacccgcaaa
gagtacgaagtggttcgtacgcagcacgcgcgtaaaaaacctcgcacgcctccggtcacg
ctgcaggccgcgcgggataacgacctggcgtttgactgggaaagttatacgccgccggtg
gcccatcgcctcggcgtgcaggaagtgaccgccagcatcgaaacgctgcgaaactacatc
gactggacgccgttctttatgacctggtcgctggccgggaaatacccgcgcatcctggaa
gatgaggtggtaggcgatgaggcgaaacgcctgtttaaagatgccaacgatatgctcgat
atgctccaccgtagtaagacgatgacaccgcgcggcgtggtcggcctgttcccggcgaac
cgtgttgacgatgatgtggagatttataccgatgagacaaggacgcgggttaaagccgta
agccgtcatctgcgccagcaaactgaaaaaagtggcttcccgaattactgcattgccgac
tttgtcgcgccgaagcacagcggtaaagcggactacatcggcgcctttgcggtcaccggc
gggattgaagaggatgacctggccggcgcctatgacgcacagcacgatgattacaacaaa
atcatggtgaaggccgtcgccgatcgtctggccgaggcctttgcggagtatctccacgag
cgagtgcgtaaagtctattggggctatgccgctacggaaaacctcagcaacgaggagctg
atccgcgagaattatcaggggattcgcccggctccaggttacccggcctgcccggagcac
acggaaaaagcggctatctgggaactgcttgacgtagaaaacgtgattggcatgaagctc
accgagtcttacgctatgtggcccggcgcgtcggtttctggctggtacttcagccatccg
gacagcaagtacttcgccgtggcgcagattcagcgcgaccaggttgaagactatgcgagg
cgtaaagggatgccggtcagtgaagttgagcgctggctggcgccgaacctgggctatgat
gctgactag
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