KEGG Orthology (KO) [BR:clud00001]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
112641868
00670 One carbon pool by folate
112641868
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
112641868
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
112641868
Enzymes [BR:clud01000]
1. Oxidoreductases
1.5 Acting on the CH-NH group of donors
1.5.1 With NAD+ or NADP+ as acceptor
1.5.1.3 dihydrofolate reductase
112641868
151 aa
MAGDSSDAQLVVVVRAGGKSQGQLAWELLADCQDRINIVLSRDLKEPPQGAHFLAKSLDD
ALKLTEQPELANKVDMVWIVGGSSVYKEAMNKPGHLRLFVTRIMHEFESDTFFPEIDLEK
YKLLPEYPGVLSDVQEEKGIKYKFEVYEKND