KEGG   Canis lupus dingo (dingo): 112651170
Entry
112651170         CDS       T08371                                 
Symbol
HK3
Name
(RefSeq) hexokinase-3 isoform X2
  KO
K00844  hexokinase [EC:2.7.1.1]
Organism
clud  Canis lupus dingo (dingo)
Pathway
clud00010  Glycolysis / Gluconeogenesis
clud00051  Fructose and mannose metabolism
clud00052  Galactose metabolism
clud00500  Starch and sucrose metabolism
clud00520  Amino sugar and nucleotide sugar metabolism
clud00524  Neomycin, kanamycin and gentamicin biosynthesis
clud01100  Metabolic pathways
clud01200  Carbon metabolism
clud01250  Biosynthesis of nucleotide sugars
clud04066  HIF-1 signaling pathway
clud04910  Insulin signaling pathway
clud04930  Type II diabetes mellitus
clud04973  Carbohydrate digestion and absorption
clud05230  Central carbon metabolism in cancer
Module
clud_M00001  Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
clud_M00549  UDP-Glc biosynthesis, Glc => UDP-Glc
clud_M01015  GDP-Man biosynthesis, Man => GDP-Man
Brite
KEGG Orthology (KO) [BR:clud00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    112651170 (HK3)
   00051 Fructose and mannose metabolism
    112651170 (HK3)
   00052 Galactose metabolism
    112651170 (HK3)
   00500 Starch and sucrose metabolism
    112651170 (HK3)
  09107 Glycan biosynthesis and metabolism
   00520 Amino sugar and nucleotide sugar metabolism
    112651170 (HK3)
  09110 Biosynthesis of other secondary metabolites
   00524 Neomycin, kanamycin and gentamicin biosynthesis
    112651170 (HK3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04066 HIF-1 signaling pathway
    112651170 (HK3)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    112651170 (HK3)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    112651170 (HK3)
 09160 Human Diseases
  09161 Cancer: overview
   05230 Central carbon metabolism in cancer
    112651170 (HK3)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    112651170 (HK3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:clud04131]
    112651170 (HK3)
Enzymes [BR:clud01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.1  hexokinase
     112651170 (HK3)
Membrane trafficking [BR:clud04131]
 Autophagy
  Mitophagy
   Other mitophagy associated  proteins
    112651170 (HK3)
SSDB
Motif
Pfam: Hexokinase_2 Hexokinase_1
Other DBs
NCBI-GeneID: 112651170
NCBI-ProteinID: XP_035570979
Ensembl: ENSCAFG00020011669
LinkDB
Position
4:36866850..36919226
AA seq 953 aa
MPHTEREELTPKESNQLLLPGGHPPMWNHMDSIGPIGLPHREGVPGCSQEGLPYPSNSSE
LVLECLQQFKVTETQLQQIQASLLDSMEQALGGQASPASAVRMLPTYVGSIPHGTEQGDF
VVLELGATGASLRVLWVTLMGTGGHRMEPRSQEFVIPPEVMLGPGQQLFDFAAHCLSEFL
DALPVGKQGLQLGFSFSFPCHQTGLDRSTLISWTKGFRCSGVEGHDVVHLLRDAIKRHGA
YNIDVVAVVNDTVGTMMGCEPGVGPCEVGLVVDTGTNACYMEEARHVAVLDEDRGRVCVS
VEWGSFGDDGVLGPMLTIFDHALDRESLNPGAQRFEKMIGGLYLGELVRLVLVHLAQRGV
LFGGCTSPALLSRGSILLEHVAEMEDPWAGAARVHALLQDLGLNVGASDVELVQYVCAAV
FTRAARLCAAALAAVLSRLQHSREQQILQIAVATGGRVFEQHPSFLSILQETVMLLTPEC
DVSFIPSVDGGGRGVAMVTAVAARLAAHRHLLEETLAPFQLNHEQLAAVQAQMREAMVKG
LRGEASSLRMLPTYVRATPDGSERGDFLALDLGGTNFRVLLVRVTAEGVKITNQIYSIPE
NVAQGSGQQLFDHIVDCIVDFQQKQGLSGQSLPLGFTFSFPCRQLGLDQGILLNWTKGFS
ASDCEGQDIVCLLREAIGRRQAVELNVVAIVNDTVGTMMSCGYEDPRCEVGLIVGTGTNA
CYMEELRNVAAVAGDSGQMCINMEWGAFGDDGSLGLLRTCFDASVDQASINPGKQSFEKM
ISGMYLGEIVRHILLHLTSLGVLFRGQQTQRLQTRDIFKTKFLSEIESDSLALRQVRAIL
EDLGLSLTSDDALMVLEVCQAVSQRAAQLCGAGVAAVVEKIRENRGLEELTVSIGVDGTL
YKLHPHFSSLVAATVRELAPRCVVTFLQSEDGSGKGAALVTAVACRLAQMARV
NT seq 2862 nt   +upstreamnt  +downstreamnt
atgcctcacactgagagagaagagctcacgcctaaggaaagtaaccaactacttctccca
ggtggccaccctccaatgtggaaccacatggactccattgggccaatagggttgccgcac
agggaaggagtccctggctgctcccaggagggcttgccctacccctcaaacagctctgag
ctggtgttggagtgtctacagcagttcaaggtgacggagacacagctgcagcagatccaa
gccagcctcctggactctatggagcaggcactggggggtcaggccagccctgcctctgct
gtccggatgctgcccacatacgtggggtccatcccacatggcactgagcaaggagatttt
gtggtgctggagctgggggccacaggggcctcactgcgtgttctgtgggtgaccctgatg
ggcactggggggcataggatggagccccggagccaggagtttgtgatccccccagaggtg
atgctgggtcctggtcagcagctctttgactttgctgcccactgcctgtctgaattcctg
gatgcactccccgtgggaaaacaaggtctacaacttgggttcagcttctccttcccttgt
caccagacaggcctggacaggagcacccttatttcctggaccaaaggttttaggtgcagt
ggtgtggaaggccacgatgtggtccatttgctgcgagatgccatcaagaggcatggggcc
tacaacatcgatgtggttgctgtggtgaatgacacagtgggcaccatgatgggctgcgag
ccaggggttgggccgtgtgaggtcgggcttgttgtagacactggcaccaatgcatgttac
atggaggaggcaaggcatgtggcagtgctggacgaggaccggggccgtgtctgcgtcagc
gttgagtggggctccttcggtgatgatggggtcctgggaccaatgctgaccatctttgat
catgctttggatcgagagtccctgaatcctggtgcccagaggtttgagaagatgattggg
ggcttgtacctgggtgagctggtgaggcttgtgttggttcacctggcccagcgaggggtc
ctctttggtggctgcacctcccctgccctgctgagccgaggtagcatcctcctggagcac
gtggctgagatggaggacccctgggctggggcagcccgtgtgcatgctctcctgcaggac
ttgggcctgaacgtgggggcctcagatgttgagctcgtgcagtatgtatgtgcagctgtg
tttactcgggctgcccggctctgtgctgccgccctggctgctgttctctctcgcctccag
cacagccgggagcagcagatacttcagattgctgtggccaccggaggccgagtatttgag
caacaccccagttttctcagcatcctgcaggagactgtaatgctcctaacccccgaatgt
gatgtctccttcattccctctgtggatgggggtggccggggcgtggcaatggtgactgct
gtggctgcccgcctggctgctcaccggcacctgctggaagagaccctggcacctttccaa
ttgaaccatgaacagctggcagcagtgcaggcacagatgcgggaggccatggtcaagggg
ctccgaggggaggcatcatccctccgcatgttgcccacttatgtccgggccacgcctgat
ggcagtgagcgtggggacttcctggccctggacctggggggcaccaacttccgggttctc
ctggtgcgtgtgactgcagaaggtgtgaagatcaccaaccagatctattccatcccagag
aatgtggcccagggctctggacagcagctctttgatcacatcgtggactgcattgtggac
ttccagcagaagcagggcctgagtgggcagagccttccgctgggtttcaccttctccttc
ccatgcaggcagcttggccttgatcagggcatcctcctaaattggacaaagggtttcagt
gcgtcagattgtgagggtcaagacattgtgtgtctgcttcgggaagccattgggcgaaga
caggcagtggagctgaatgtggttgccattgtgaatgacacggtggggaccatgatgtcc
tgtggctatgaggatccccgttgtgaggtcggcctcatcgttgggactggcaccaatgcc
tgttacatggaagagcttcggaatgtggcagctgtagctggggactcagggcagatgtgc
atcaatatggagtggggtgcctttggggatgatgggtctctgggcttacttagaacctgc
tttgatgcaagtgtggaccaggcatccatcaaccctggcaagcagagttttgagaagatg
atcagtggcatgtacctgggagagattgtccgccacattcttttgcatttgaccagcctt
ggagttcttttccggggccagcagacccagcgccttcagaccagggacatcttcaagacc
aagtttctctctgagattgaaagtgacagtctagctctgaggcaggtccgagccatcctg
gaagatctggggctgtccctgacttcagatgatgccctgatggtcctggaggtgtgccaa
gctgtgtcccagcgggctgcccagctctgtggggcaggtgtggctgctgtggtggagaag
atccgtgagaaccggggcctagaagagctgactgtgtccataggggtggatgggaccctc
tataagctacacccccacttctccagcctggtggcagccaccgtgagggagctggcccct
cgctgtgtggtcaccttcctgcagtcagaagatgggtccggcaaaggtgcagccctggtc
actgctgttgcctgccgccttgcccagatggcccgtgtttga

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