Canis lupus dingo (dingo): 112655359
Help
Entry
112655359 CDS
T08371
Symbol
BRCA1
Name
(RefSeq) breast cancer type 1 susceptibility protein isoform X1
KO
K10605
breast cancer type 1 susceptibility protein [EC:
2.3.2.27
]
Organism
clud
Canis lupus dingo (dingo)
Pathway
clud01524
Platinum drug resistance
clud03440
Homologous recombination
clud03460
Fanconi anemia pathway
clud04120
Ubiquitin mediated proteolysis
clud04151
PI3K-Akt signaling pathway
clud05206
MicroRNAs in cancer
clud05224
Breast cancer
Brite
KEGG Orthology (KO) [BR:
clud00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
112655359 (BRCA1)
09124 Replication and repair
03440 Homologous recombination
112655359 (BRCA1)
03460 Fanconi anemia pathway
112655359 (BRCA1)
09130 Environmental Information Processing
09132 Signal transduction
04151 PI3K-Akt signaling pathway
112655359 (BRCA1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
112655359 (BRCA1)
09162 Cancer: specific types
05224 Breast cancer
112655359 (BRCA1)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
112655359 (BRCA1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
clud01009
]
112655359 (BRCA1)
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
clud04121
]
112655359 (BRCA1)
03036 Chromosome and associated proteins [BR:
clud03036
]
112655359 (BRCA1)
03400 DNA repair and recombination proteins [BR:
clud03400
]
112655359 (BRCA1)
Enzymes [BR:
clud01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.27 RING-type E3 ubiquitin transferase
112655359 (BRCA1)
Protein phosphatases and associated proteins [BR:
clud01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
112655359 (BRCA1)
Ubiquitin system [BR:
clud04121
]
Ubiquitin ligases (E3)
Single Ring-finger type E3
Other single Ring-finger type E3
112655359 (BRCA1)
Multi subunit type E3
BRCC complex
112655359 (BRCA1)
Chromosome and associated proteins [BR:
clud03036
]
Eukaryotic type
Centrosome formation proteins
Centrosome duplication proteins
Regulators of centriole replication
112655359 (BRCA1)
DNA repair and recombination proteins [BR:
clud03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
BRCA1-core complex
112655359 (BRCA1)
BRCA1-A complex
112655359 (BRCA1)
BRCA1-B complex
112655359 (BRCA1)
BRCA1-C complex
112655359 (BRCA1)
BRCA complex
112655359 (BRCA1)
FA (Fanconi anemia) pathway
Downstream FA components
112655359 (BRCA1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
BRCT_assoc
BRCT
zf-C3HC4
zf-RING_5
zf-C3HC4_2
zf-RING_2
BRCT_2
zf-ANAPC11
zf-C3HC4_4
zf-C3HC4_3
zf-rbx1
zf-RING_UBOX
RING_XB3-XBAT31
zf-RING_10
zf-RING_4
TRAF3_RING
Prok-RING_4
Motif
Other DBs
NCBI-GeneID:
112655359
NCBI-ProteinID:
XP_025296215
LinkDB
All DBs
Position
9:21082388..21149264
Genome browser
AA seq
1934 aa
AA seq
DB search
MVREQGPFLRLSQALSCAHIRASGSDSSHLCDVISPEWKPKEKMDLSADRVEEVQNVLNA
MQKILECPICHLPMLETQNANTRLELIKEPVSTKCDHIFCKFCMLKLLNQRKGPSQCPLC
KNDITKRSLQESTRFSQLVEELLKIIHAFELDTGLQFADSYNFSKKENNSPEHLKEEVSI
IQSMGYRNRAKRLRQSEPENPTLETSLSVQLSNLGIVRSLRTKQQIQPQNKSVYIELGSD
SSEDTVNKASSCSVGDDKLEITSQGARAEASLNPAKKAACEFSGDITNIEHHQSGNKDLT
TTEKHATKKHPEKYQGISVSNLHVEPCGTNTHASSLQHENSSLLLTKHRMNVEKAEICNN
SKQPGLARSQQSRWAESKETCNDRQIPSTEKKVVVNADLLCGRKELNKQKPPHSDSPRDS
QDVPWITLNSSIRKVNEWFSRSDEILTSDDSHDRGSELNTEVGGAVEVPNEVGEYSGSSE
KIDLMASDPQDAFICESERVHTKPVGGNIEDKIFGKTYRRKASLPKVSHTTEVLTIGACA
IEPQTMQTHPFMNKAEHKRRTTSSLHPEDFIKKVELGIVPKTPEKLIEGINQIKRDGHVI
NITNNGPENETEGDYVQKEKNANPTESLEKESAFRTKTEPMSSRISNMELELNSSSSKAP
KKNRLRRKSSARHTCALEFVVNRNLNPPDHSELQIESCSSSEEMKKQHLDQVPVRHNKTL
QLMQDKEPAGRAKKSSKPGEQINKRLASHAFPELTLTNVSGFFANYSSSSKPQECINPGL
RREEIEESRRMTQVSDSTRDPKELVLSGGRGLQTERSVESTSISLVLDTDYGTQDSISLL
EADTLRKAKTVSNQQANLCATIENPKEPIHGCSKDTRNDTEGFVVPLTCKDNHTQETSIE
MEESELDTQCLRNMFKVSKRQSFALFSYPRDPEEDCVTVCPRSGAFGKQGPKVTLECGQK
EESQGKKESEIRHVQAVHTNAGFSAVSQKAKKPGDFAKCSIKGVSRLCLSSQFKGKETEL
LIANYHGISQNPYHIPPLSPIRSCVKTLCQENLSEEKFEQHSMSPERAVGNERVIQSTVS
TISQNNIRECASKEVGSSSVNEVVSSTNEVGSSVNEVGSSGENIQAELGRNRGPKLNAML
RLGLMQPEVCKQSLSLSNCKHPEMKWQGQSEGAVLSVSADFSPCLISDNPEQPMGSSRSS
QVCSETPDDLLNGDKIKGKVSFAESDIKEKSAVFSKSVQSGEFSRSPSPSDHTRLAQGYQ
RGTKKLESSEENMSSEEEELPCFQHLIFGKVTNMPSQSTSHNAVAAEGLSNKTEENLDSL
KNSLSDISNQVPSAKASQEHHLSEEARCSGSLFSSQCSALEDLTVNTNTQDPFSMFDPTS
KQVRHQSENLDVLNDKELVSDDDDEREPGLEEDSPQEEQSVDSDLGEVASGYESETSLSE
DCSRLSSQSDILTTQQRDTMQDNLIKLQQEMAELEAVLEQHESQPSNSSPSLIADSCSPE
DLLNPEQNASERVLTSEKSSDSPISQNPESLSTDKFQVFLDSSTSKNGEPGMIRSSPSQS
RLLDTRWYVHSCPRSLQDTNCPSQKELTKVVSMEEQQPTESEARDLMEQSYLSRPDLEGA
PYLESGISLFSDDPESDPSSHRASELAHVSSMPTSTSALKLPQFQVEESAKSTAAVHIAS
TAGYNKSEDSVGIEKPEVISSTRGVNKRISMVASGLTPKEFMLVHKFARKHHISLTNLIS
EETTHVIMKTDAEFVCERTLKYFLGIAGGKWVVSYFWVTQSIKERKILDEHDFEVRGDVV
NGRNHQGPKRARESQDRESQDRKIFRGLEICCYGPFTNMPTDQLEWMVHLCGASVVKEPS
LFTLSKGTHPVVVVQPDAWTEDSGFHAIGQMCEAPVVTREWVLDSVALYQCQELDTYLIP
QIPRAAADSSQPCV
NT seq
5805 nt
NT seq
+upstream
nt +downstream
nt
atggtgagggaacagggcccctttttgcgactgtctcaggcactatcttgcgctcatatt
cgggcctcaggcagtgattccagccatctctgtgacgtgataagcccagagtggaaaccc
aaggaaaaaatggatttatctgcggatcgtgttgaagaagtacaaaatgttcttaatgct
atgcagaaaatcttagagtgtccaatatgtcacttacccatgttggaaacccaaaatgca
aatacgcgtctggagttgatcaaagagcctgtttctacaaagtgtgatcacatattttgc
aaattttgtatgctgaaacttctcaaccagaggaaggggccttcacagtgtcctttgtgt
aagaacgatataaccaaaaggagcctacaagaaagtacaagatttagtcaacttgttgaa
gagttgttgaaaatcattcatgcttttgagctggacacaggattgcagtttgcagacagc
tataacttttccaaaaaggaaaataactctcctgagcatctaaaggaggaagtttctatt
atccaaagtatgggctatcgaaaccgtgccaaaagacttcgacagagtgaacctgaaaac
cctaccttggaaaccagtcttagtgtccaactctctaaccttggaattgtgagatctctg
aggacaaagcagcagatacagcctcagaataagtctgtctacattgaattggggtctgat
tcttctgaagatacagttaataaggcaagttcttgcagtgtgggagatgacaagttagaa
atcacctctcaaggagccagggctgaagccagtttgaatcctgcaaaaaaggctgcttgt
gaattttctggggacataacaaatattgaacatcatcaatccggtaataaagatttgacc
accactgagaagcatgcaactaagaagcatccagaaaagtatcagggtatttctgtttca
aacttgcatgtggagccatgtggcacaaatactcatgccagctcattacagcatgagaac
agcagtttattactcactaaacacagaatgaatgtagaaaaggctgaaatctgtaataac
agcaaacagcctggcttagcaaggagccaacagagcagatgggctgaaagtaaggaaaca
tgtaatgataggcagattcccagcacagagaaaaaggtagttgtgaatgctgatctcctg
tgtgggagaaaagaactgaataaacagaaacctccacactctgatagtcctagagattcc
caagatgttccttggataacactgaatagtagcatacggaaagttaatgagtggttttcc
agaagtgacgaaatattaacttctgatgattcacatgacagaggatctgaattgaatact
gaagtaggtggtgcagtagaagttccaaatgaagtgggtgaatattctggttcttctgag
aaaatagacttaatggccagtgatcctcaggatgctttcatatgtgaaagtgaaagagtc
cacaccaagccagtaggaggtaatatcgaagataaaatatttggaaaaacctatcggagg
aaggcaagcctccctaaggtgagccacacaactgaagttctaactataggagcgtgtgct
atagaacctcagacaatgcaaacccatcccttcatgaataaagcagagcataaaaggaga
actacatctagccttcatcctgaggattttatcaagaaagtagagttaggcattgttcca
aagactcctgaaaagctaattgagggaatcaaccaaatcaagcgagatggtcatgtgata
aatattacaaataatggtcctgagaatgaaacagaaggtgattatgttcagaaagagaaa
aatgctaacccaacagaatcattggaaaaagaatctgcttttagaaccaaaactgaacca
atgagcagcaggataagcaatatggaactggaattaaatagctccagttcaaaagcacct
aagaagaacaggctgaggaggaagtcctctgccaggcacacttgtgcccttgaattcgta
gtcaatagaaatctaaacccacctgatcatagtgaactacagattgaaagttgttctagc
agtgaagagatgaagaaacagcatctggaccaagtaccagtcagacacaacaaaacactt
cagctcatgcaagataaagaacctgcaggtagagctaagaaaagtagtaagccaggagaa
caaataaataagagactcgccagccatgcttttccagagctaactttaacaaatgtatct
ggtttttttgctaactattcaagttctagtaagcctcaagagtgcatcaaccctggcctt
cgaagagaagaaatagaagagagccgaagaatgactcaagtgtctgatagtaccagagat
cccaaagagctggtattgagtggaggaagaggtttgcaaactgagagatctgtagagagt
accagtatttcattggtacttgatactgattatggtacacaggacagtatctcattactg
gaagctgacaccctgaggaaggcaaaaacagtatcaaatcaacaggcgaatctgtgtgca
acaattgagaaccccaaggaacctatccatggttgttctaaggacactagaaatgacaca
gagggttttgtagttccattgacgtgcaaagataaccacactcaagagacaagcatagaa
atggaagagagtgaacttgacacgcagtgcttacgcaatatgttcaaggtttcaaagcgt
cagtcatttgctctgttttcatatccaagagatccggaagaggactgtgtaacagtctgt
ccccgctctggggcctttggaaaacaaggtccaaaagtcactctagaatgtggacagaaa
gaagaaagtcagggaaagaaagagtctgaaatcagacatgtgcaggcagttcatacaaat
gcaggcttttctgcagttagtcagaaagctaagaagccaggcgattttgccaaatgtagc
ataaagggagtctctcggctttgtctgtcatctcagttcaaaggcaaggaaactgaactc
cttattgcaaattaccatggaatttcccaaaacccttatcatataccaccactttctccc
atcagatcatgtgttaaaactctatgtcaggaaaacctgtcagaggaaaagtttgagcaa
cattcaatgtcacccgaaagagcagtgggaaatgagagagtcattcaaagtacagtgagc
acaattagccaaaataacattagagaatgtgcttctaaagaagtcggctcaagcagtgtt
aatgaagtagtttccagtactaatgaagtaggctctagtgttaatgaagtaggttccagt
ggtgaaaacattcaagcagaactaggtagaaaccgaggacctaaattaaatgctatgctc
agattaggtcttatgcaacctgaagtctgtaagcaaagcctttctttaagtaattgtaaa
catccagaaatgaaatggcaaggacaaagtgaaggagcagttctgtctgttagtgcagat
ttctctccatgtctgatttcagataacccagaacaacctatgggaagtagtcggtcttct
caggtttgttctgagacacctgatgacctattaaatggtgacaaaataaagggaaaagtc
agctttgctgaaagtgacattaaggaaaaatctgctgtgtttagcaaaagtgtccagagt
ggagagttcagcagaagccctagcccttcagaccatacacgtttggcccagggttaccag
agagggaccaagaaattagagtcctcagaagagaacatgtctagtgaggaggaagagctt
ccctgcttccaacacttaatatttggtaaagtaaccaacatgccttctcagtctaccagt
cacaatgcagttgccgcagagggtctatctaacaaaacagaggagaacctagactcattg
aagaatagtttaagtgacatcagtaaccaggtaccgtcagcaaaggcatcccaggaacat
caccttagtgaggaagcaagatgttctggcagcttattttcttcacagtgcagtgctttg
gaagacttgactgtaaatacaaatacccaggatcctttctcgatgtttgatcctacttcc
aaacaagtgaggcatcaatctgaaaatctggacgttctgaatgacaaggaattggtttca
gatgatgatgatgaaagggaacctggcctggaagaggatagtcctcaagaagagcagagt
gtggattcagacttaggtgaagtggcatctggatatgagagtgaaacgagcctctctgaa
gactgttccaggttgtcctctcagagtgatattttaaccactcagcagagagataccatg
caagataacctgataaagctccagcaggaaatggctgaactggaagctgtgttagagcag
catgagagccagccctctaacagctccccttcccttatagcagattcttgttcgcctgag
gatctgctgaatccggaacaaaacgcatcagaaagagtattaacttcagagaaaagtagt
gactctcctataagccagaatcccgaaagcctttctactgacaaatttcaagtatttctg
gatagttccaccagtaaaaatggagaaccaggaatgatacggtcttccccttcacagtcc
cggttgttagatactagatggtatgtacacagctgcccaaggagtcttcaggacactaac
tgcccatctcagaaggagctcactaaggttgtcagtatggaggagcaacaaccaactgag
tcagaagcaagagatctcatggagcaatcttatttgtcaagaccagatctggagggagcc
ccttacctcgaatctggaatcagccttttctctgatgaccctgagtctgatccctcgtca
cacagagcctcagagctggctcatgttagcagcatgccaacttcaacctctgcgttgaaa
ttaccccaatttcaggtcgaagaatcagccaagagtacagctgctgtccatattgctagt
actgctgggtataataaaagcgaagacagtgtgggcatagaaaagccagaagtgatatct
tcaacaagaggagtcaacaaaagaatatctatggtggcatcaggcttgaccccaaaagaa
tttatgcttgtgcacaagtttgccagaaaacaccacatctctttaactaatctaatttct
gaagagacaactcatgtcattatgaaaacagatgctgagtttgtgtgcgaacgaacactg
aaatattttctgggtattgcaggaggaaaatgggtagttagctatttctgggtaacccag
tctattaaagaaagaaagatactagatgagcatgattttgaagtcagaggagatgttgtg
aatggaagaaatcaccagggtccgaagcgagcaagagaatcccaggacagagaatcccaa
gacagaaagatcttcaggggcctagaaatctgttgctatggaccctttaccaacatgccc
acagatcaattagagtggatggtgcacctctgtggggcttctgtggtgaaggagccttcg
ttattcaccctcagcaagggcactcatccagtggtagtcgtgcagccggacgcctggaca
gaggacagtggcttccatgcgattgggcagatgtgtgaggcacctgtggtgacccgagag
tgggtactggacagtgtagccctctaccagtgccaggagctggacacctacctgatcccg
cagattcccagagctgctgcagactccagccagccatgcgtgtaa
DBGET
integrated database retrieval system
